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The map label for this gene is agaS [H]

Identifier: 209400641

GI number: 209400641

Start: 4126599

End: 4127753

Strand: Direct

Name: agaS [H]

Synonym: ECH74115_4453

Alternate gene names: 209400641

Gene position: 4126599-4127753 (Clockwise)

Preceding gene: 209398649

Following gene: 209399873

Centisome position: 74.06

GC content: 56.36

Gene sequence:

>1155_bases
ATGCCAGAAAATTACACCCCTGCTGCCGCCGCAACCGGTACATGGACTGAAGAAGAGATCCGCCATCAGCCTCGCGCATG
GATCCGTTCGCTCACCAACATCGACGCGCTACATTCCGCGCTTAATAACTTCCTTGAACCGTTACTGCGCAAAGAGAATC
TGCGGATCATCCTGACCGGAGCCGGAACCTCGGCATTTATCGGTGACATCATCGCGCCGTGGCTCGCCAGCCATACCGGT
AAAAACTTCAGCGCCGTACCGACCACCGATCTGGTCACTAATCCGATGGACTACCTGAACCCAGCCCATCCGCTGCTGTT
GATCTCCTTCGGTCGATCCGGCAACAGCCCGGAAAGCGTCGCAGCCGTGGAACTGGCAAATCAATTTGTACCGGAATGCT
ATCACCTGCCGATCACCTGCAACGAAGCGGGCGCTCTTTACCAAAACGCGATCAACAGCGATAACGCGTTTGCCGTGCTG
ATGCCCGCAGAAACGCACGATCGCGGCTTTGCGATGACCAGCAGCATTACCACCATGATGGCCAGCTGCCTCGCGGTTTT
CGCACCTGAGACGATCAACAGCCAAACCTTCCGCGACGTGGCGGATCGTTGCCAGGCGATCCTGACCTCACTGGGCGATT
TCAGCGAAGGTGTGTTTGGTTACGCACCGTGGAAACGGATCGTTTATCTCGGCAGCGGTGGCTTACAGGGCGCAGCACGC
GAGTCGGCGCTGAAAGTGCTGGAACTGACGGCGGGTAAACTGGCGGCCTTTTATGATTCTCCAACCGGATTCCGTCATGG
ACCAAAATCGCTGGTCGATAACGAAACACTGGTGGTGGTATTTGTCTCCAGCCACCCTTACACCCGTCAGTATGATCTTG
ATCTGCTGGCTGAACTTCACCGTGACAACCAGGCAATGCGTGTAATCGCCATCGCCGCGGAAAGCAGCGACATCGTCGCT
GCCGGTCCACATATCATCCTGCCACCGTCACGTCACTTTATCGACGTTGAGCAGGCATTTTGCTTCCTGATGTACGCCCA
GACGTTTGCACTGATGCAGTCGCTGCACATGGGCAATACGCCGGATACCCCATCAGCCAGTGGCACCGTTAACCGCGTGG
TGCAAGGCGTAATCATTCATCCGTGGCAGGCATAA

Upstream 100 bases:

>100_bases
AGATTTTAATCAACGAAAGACATCACCAAGTGAAATGAAACGAAAGGCAAGTGAAAGCGACAACGCCCGACGTCAAGTTC
ATCAGACTAAGGATTGAGTT

Downstream 100 bases:

>100_bases
GAGGATCGCATTATGAGCATTATCTCCACCAAATATCTGTTACAGGACGCCCAGGCCAATGGCTACGCGGTGCCTGCTTT
TAACATTCATAACGCCGAGA

Product: putative sugar isomerase, AgaS family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALHSALNNFLEPLLRKENLRIILTGAGTSAFIGDIIAPWLASHTG
KNFSAVPTTDLVTNPMDYLNPAHPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFAVL
MPAETHDRGFAMTSSITTMMASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGVFGYAPWKRIVYLGSGGLQGAAR
ESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDNETLVVVFVSSHPYTRQYDLDLLAELHRDNQAMRVIAIAAESSDIVA
AGPHIILPPSRHFIDVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVIIHPWQA

Sequences:

>Translated_384_residues
MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALHSALNNFLEPLLRKENLRIILTGAGTSAFIGDIIAPWLASHTG
KNFSAVPTTDLVTNPMDYLNPAHPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFAVL
MPAETHDRGFAMTSSITTMMASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGVFGYAPWKRIVYLGSGGLQGAAR
ESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDNETLVVVFVSSHPYTRQYDLDLLAELHRDNQAMRVIAIAAESSDIVA
AGPHIILPPSRHFIDVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVIIHPWQA
>Mature_383_residues
PENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALHSALNNFLEPLLRKENLRIILTGAGTSAFIGDIIAPWLASHTGK
NFSAVPTTDLVTNPMDYLNPAHPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFAVLM
PAETHDRGFAMTSSITTMMASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGVFGYAPWKRIVYLGSGGLQGAARE
SALKVLELTAGKLAAFYDSPTGFRHGPKSLVDNETLVVVFVSSHPYTRQYDLDLLAELHRDNQAMRVIAIAAESSDIVAA
GPHIILPPSRHFIDVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVIIHPWQA

Specific function: May be a tagatose-6-phosphate ketose/aldose isomerase [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Escherichia coli, GI1789525, Length=384, Percent_Identity=98.9583333333333, Blast_Score=787, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001347
- InterPro:   IPR014180 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: 5.-.-.- [C]

Molecular weight: Translated: 41730; Mature: 41599

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALHSALNNFLEPLLRKENLRIILTG
CCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
AGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPAHPLLLISFGRSGNSPESV
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHCCCCCCEEEEEECCCCCCCHHH
AAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFAVLMPAETHDRGFAMTSSITTMM
HHHHHHHHHCHHHEECCEEECCCHHHHHHHCCCCCCEEEEEECCCCCCCEEHHHHHHHHH
ASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGVFGYAPWKRIVYLGSGGLQGAAR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCEEEEEECCCCCCCHHH
ESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDNETLVVVFVSSHPYTRQYDLDLLAELH
HHHHHHHHHHHCHHEEEECCCCCCCCCCHHHCCCCEEEEEEECCCCCCEECCHHHHHHHH
RDNQAMRVIAIAAESSDIVAAGPHIILPPSRHFIDVEQAFCFLMYAQTFALMQSLHMGNT
CCCCEEEEEEEEECCCCEEEECCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCC
PDTPSASGTVNRVVQGVIIHPWQA
CCCCCCCCHHHHHHCCEEECCCCC
>Mature Secondary Structure 
PENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALHSALNNFLEPLLRKENLRIILTG
CCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
AGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPAHPLLLISFGRSGNSPESV
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHCCCCCCEEEEEECCCCCCCHHH
AAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFAVLMPAETHDRGFAMTSSITTMM
HHHHHHHHHCHHHEECCEEECCCHHHHHHHCCCCCCEEEEEECCCCCCCEEHHHHHHHHH
ASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGVFGYAPWKRIVYLGSGGLQGAAR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCEEEEEECCCCCCCHHH
ESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDNETLVVVFVSSHPYTRQYDLDLLAELH
HHHHHHHHHHHCHHEEEECCCCCCCCCCHHHCCCCEEEEEEECCCCCCEECCHHHHHHHH
RDNQAMRVIAIAAESSDIVAAGPHIILPPSRHFIDVEQAFCFLMYAQTFALMQSLHMGNT
CCCCEEEEEEEEECCCCEEEECCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCC
PDTPSASGTVNRVVQGVIIHPWQA
CCCCCCCCHHHHHHCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 8932697 [H]