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The map label for this gene is rnhB [H]

Identifier: 209400402

GI number: 209400402

Start: 207817

End: 208413

Strand: Direct

Name: rnhB [H]

Synonym: ECH74115_0193

Alternate gene names: 209400402

Gene position: 207817-208413 (Clockwise)

Preceding gene: 209399982

Following gene: 209398477

Centisome position: 3.73

GC content: 56.62

Gene sequence:

>597_bases
ATGATCGAATTTGTCTATCCGCACACGCAGCTGGTTGCGGGTGTGGATGAAGTCGGACGCGGGCCGTTAGTTGGCGCGGT
CGTCACCGCTGCGGTGATTCTCGACCCGGCGCGCCCGATTGCCGGGCTGAATGATTCCAAAAAGCTGAGCGAAAAACGTC
GTCTGGCGCTCTGTGAAGAGATCAAAGAGAAAGCGTTGAGCTGGAGTCTGGGCCGCGCGGAACCTCACGAAATCGACGAA
CTGAATATTTTACATGCGACCATGCTGGCGATGCAGCGAGCCGTCGCTGGGCTGCATATTGCGCCGGAATATGTGTTGAT
TGATGGTAACCGCTGCCCGAAATTACCGATGCCTGCGATGGCTGTGGTGAAAGGCGATAGCCGCGTACCGGAAATCAGTG
CCGCGTCTATCCTGGCGAAAGTGACGCGTGACGCCGAAATGGCGGCGCTGGATATTGTTTTCCCGCAATATGGTTTTGCC
CAACACAAAGGGTATCCAACCGCTTTTCATCTGGAAAAACTGGCTGAACACGGCGCGACCGAACACCATCGGCGCAGCTT
TGGGCCTGTCAAACGCGCACTGGGACTTGCGTCCTGA

Upstream 100 bases:

>100_bases
AAACCAGCCACGCGATGCACGATACCTTCCGTGAACTGCATCAGCAGATCCGCTGCAATGCCGATGAGCAGGCGGCACAA
GCCGTTCTGGAGTTAGCACA

Downstream 100 bases:

>100_bases
TTCTTGTGTCGAGATTAAGTAAACCGGAATCTGAAGATGTCTGAACCACGTTTCGTACACCTGCGGGTGCACAGCGACTA
CTCGATGATCGATGGCCTGG

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDE
LNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS

Sequences:

>Translated_198_residues
MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDE
LNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS
>Mature_198_residues
MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDE
LNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=198, Percent_Identity=99.4949494949495, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 21466; Mature: 21466

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALCEE
CCEEECCHHHHHHCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
IKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAM
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEECCCEEEEECCCCCCCCCCCE
AVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEHGAT
EEEECCCCCCCHHHHHHHHHHHCCHHHHEEEEECCCCCCHHHCCCCHHHHHHHHHHCCCC
EHHRRSFGPVKRALGLAS
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALCEE
CCEEECCHHHHHHCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
IKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAM
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEECCCEEEEECCCCCCCCCCCE
AVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEHGAT
EEEECCCCCCCHHHHHHHHHHHCCHHHHEEEEECCCCCCHHHCCCCHHHHHHHHHHCCCC
EHHRRSFGPVKRALGLAS
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA