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The map label for this gene is uspC

Identifier: 209400371

GI number: 209400371

Start: 2487199

End: 2487627

Strand: Direct

Name: uspC

Synonym: ECH74115_2632

Alternate gene names: 209400371

Gene position: 2487199-2487627 (Clockwise)

Preceding gene: 209401004

Following gene: 209398984

Centisome position: 44.64

GC content: 45.22

Gene sequence:

>429_bases
ATGAGCTATAGCAATATTCTTGTCGCTGTTGCGGTTACACCGGAAAGTCAGCAACTGCTGGCAAAAGCGGTATCTATCGC
CAGGCCAGTAAAGGGACACATCAGTTTAATTACTCTCGCTTCCGACCCGGAAATGTACAATCAATTAGCTGCGCCGATGC
TTGAAGATTTACGCAGCGTGATGCAGGAAGAAACGCAAAGCTTTCTTGATAAGTTAATTCAGGATGCGGGGTATCCCGTT
GACAAGACGTTTATTGCCTACGGTGAGTTAAGCGAACATATTCTGGAAGTTTGTCGCAAATATCATTTCGATTTGGTGAT
TTGCGGTAATCACAATCACAGTTTCTTTTCGCGAGCATCCTGCTCGGCGAAAAGAGTGATTGCCTCAAGTGAGGTCGATG
TGCTGTTAGTTCCACTTACGGGAGATTAA

Upstream 100 bases:

>100_bases
GACTAATATTTACCTGTTTGACTGAGTTGGGATTGCGTCGTTTCTCCATTAGGAGTAAAGCTTTAATGTCACCTGAAGTT
CACAGAATAAGGAACAGGTT

Downstream 100 bases:

>100_bases
CCGCTCCTACACAAGCTTAGGAAAGGTAGCAACTTTATCGCGCTGCTGGCTTTCCGCGCTTCGCGGAACTATCTGCTTTA
GGTCGCTAATGAAGCACTCC

Product: universal stress protein UspC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPEMYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPV
DKTFIAYGELSEHILEVCRKYHFDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD

Sequences:

>Translated_142_residues
MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPEMYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPV
DKTFIAYGELSEHILEVCRKYHFDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD
>Mature_141_residues
SYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPEMYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPVD
KTFIAYGELSEHILEVCRKYHFDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD

Specific function: Required for resistance to DNA-damaging agents

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family

Homologues:

Organism=Escherichia coli, GI1788205, Length=142, Percent_Identity=97.887323943662, Blast_Score=286, Evalue=4e-79,
Organism=Escherichia coli, GI1789909, Length=140, Percent_Identity=39.2857142857143, Blast_Score=105, Evalue=8e-25,
Organism=Escherichia coli, GI1790358, Length=140, Percent_Identity=32.1428571428571, Blast_Score=79, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): USPC_ECO57 (Q8X560)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   C90954
- PIR:   H85802
- RefSeq:   NP_288331.1
- RefSeq:   NP_310630.1
- ProteinModelPortal:   Q8X560
- SMR:   Q8X560
- EnsemblBacteria:   EBESCT00000025395
- EnsemblBacteria:   EBESCT00000059402
- GeneID:   915311
- GeneID:   961866
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2948
- KEGG:   ecs:ECs2603
- GeneTree:   EBGT00050000009429
- HOGENOM:   HBG733992
- OMA:   SIARPVN
- ProtClustDB:   PRK10116
- BioCyc:   ECOL83334:ECS2603-MONOMER
- GO:   GO:0005737
- InterPro:   IPR014729
- InterPro:   IPR006016
- Gene3D:   G3DSA:3.40.50.620

Pfam domain/function: PF00582 Usp

EC number: NA

Molecular weight: Translated: 15669; Mature: 15538

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPEMYNQLAAPMLEDLRSV
CCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
MQEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCRKYHFDLVICGNHNHSFFSRAS
HHHHHHHHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHCC
CSAKRVIASSEVDVLLVPLTGD
CCHHHHEECCCCCEEEEEECCC
>Mature Secondary Structure 
SYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPEMYNQLAAPMLEDLRSV
CCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
MQEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCRKYHFDLVICGNHNHSFFSRAS
HHHHHHHHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHCC
CSAKRVIASSEVDVLLVPLTGD
CCHHHHEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796