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The map label for this gene is 209400359

Identifier: 209400359

GI number: 209400359

Start: 2613805

End: 2614464

Strand: Direct

Name: 209400359

Synonym: ECH74115_2810

Alternate gene names: NA

Gene position: 2613805-2614464 (Clockwise)

Preceding gene: 209397362

Following gene: 209398453

Centisome position: 46.91

GC content: 42.58

Gene sequence:

>660_bases
TTGCAGGAGAAAATGATGGAAAGCCTTGGCTTCAGGCTTAAGAGACTTAGAAAAGATAAGGGGCTGACCCAAGTAGAACT
GGGTAAGCTTTCAGGCGTGACTGGGGTTACTATAGGGTACTGGGAGAAAGATCTAAACGAACCAGGTAGCAAAGCTCTAA
GTAAGTTAGCCCAGGCATTAGGAACTACTGAGTCCTATCTCCTATATGGAGTATCGTCTCCTGAATTATCTTTTGTACAA
AGTACCTCAGGCACCAAGATCCCCTACCTTTCGTGGGGTGAGGCGATTTCTTTCCTAATCTTAAAAGGAGAGAAAACAAT
GGGAAATGTCGATAGAATCACCACATTCTTTGATGTCGAGGAAGGTGATTTTGCCGTTTCAATGCCTGATGACACAATGC
ATAACCCATCAGGATCACCGAGTATCCCAGTTGGTGCTACTGTGATCCTAAGGCCAGGAGAAAGTTATAAAAATGGCAGC
ATCGTCGCTGTAATAGTTCCGGATCCGCTTAAAAATGAACCATCTATGACTATAAAGAAATTAGTTATTGATGGGAAGCT
TGTGTATTTAAGCCCTCTCAATCCACGCTATCAGTCATCCTTACTTACACCAGAGTGTAAAATTGTTGCCGTAGCAAAAG
GTGTACAGTTCAACTTATAA

Upstream 100 bases:

>100_bases
AAGTTCATCAACTCGCATTTTACCTCCCAAATCTAAGTATTTTTAGATTACAAGATAATTTTTTTTAGGTCAATGCAATC
TAAAATAATTTATATTCAAT

Downstream 100 bases:

>100_bases
CCCGCCACGTCCTTTACTTGAGGTCGGCAATGCCGACCTTTTTTTTAAATTAATCTAGATTTACCTTGACTGAAAAACTA
AATACTTTTAGATTTATTAC

Product: putative repressor protein

Products: NA

Alternate protein names: ORF-96 protein [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MQEKMMESLGFRLKRLRKDKGLTQVELGKLSGVTGVTIGYWEKDLNEPGSKALSKLAQALGTTESYLLYGVSSPELSFVQ
STSGTKIPYLSWGEAISFLILKGEKTMGNVDRITTFFDVEEGDFAVSMPDDTMHNPSGSPSIPVGATVILRPGESYKNGS
IVAVIVPDPLKNEPSMTIKKLVIDGKLVYLSPLNPRYQSSLLTPECKIVAVAKGVQFNL

Sequences:

>Translated_219_residues
MQEKMMESLGFRLKRLRKDKGLTQVELGKLSGVTGVTIGYWEKDLNEPGSKALSKLAQALGTTESYLLYGVSSPELSFVQ
STSGTKIPYLSWGEAISFLILKGEKTMGNVDRITTFFDVEEGDFAVSMPDDTMHNPSGSPSIPVGATVILRPGESYKNGS
IVAVIVPDPLKNEPSMTIKKLVIDGKLVYLSPLNPRYQSSLLTPECKIVAVAKGVQFNL
>Mature_219_residues
MQEKMMESLGFRLKRLRKDKGLTQVELGKLSGVTGVTIGYWEKDLNEPGSKALSKLAQALGTTESYLLYGVSSPELSFVQ
STSGTKIPYLSWGEAISFLILKGEKTMGNVDRITTFFDVEEGDFAVSMPDDTMHNPSGSPSIPVGATVILRPGESYKNGS
IVAVIVPDPLKNEPSMTIKKLVIDGKLVYLSPLNPRYQSSLLTPECKIVAVAKGVQFNL

Specific function: May control the expression of the integrase and inhibit excision of the mobile element R391, and regulate the expression of other genes as well [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR010982
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF01381 HTH_3; PF00717 Peptidase_S24 [H]

EC number: NA

Molecular weight: Translated: 23820; Mature: 23820

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKMMESLGFRLKRLRKDKGLTQVELGKLSGVTGVTIGYWEKDLNEPGSKALSKLAQAL
CCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECHHHCCCCHHHHHHHHHHHH
GTTESYLLYGVSSPELSFVQSTSGTKIPYLSWGEAISFLILKGEKTMGNVDRITTFFDVE
CCCCEEEEEECCCCCEEEEECCCCCCCCEEECCCEEEEEEEECCCCCCCHHHEEEEEEEC
EGDFAVSMPDDTMHNPSGSPSIPVGATVILRPGESYKNGSIVAVIVPDPLKNEPSMTIKK
CCCEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCCEEEE
LVIDGKLVYLSPLNPRYQSSLLTPECKIVAVAKGVQFNL
EEECCEEEEECCCCCHHHHCCCCCCEEEEEEECCEEECC
>Mature Secondary Structure
MQEKMMESLGFRLKRLRKDKGLTQVELGKLSGVTGVTIGYWEKDLNEPGSKALSKLAQAL
CCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECHHHCCCCHHHHHHHHHHHH
GTTESYLLYGVSSPELSFVQSTSGTKIPYLSWGEAISFLILKGEKTMGNVDRITTFFDVE
CCCCEEEEEECCCCCEEEEECCCCCCCCEEECCCEEEEEEEECCCCCCCHHHEEEEEEEC
EGDFAVSMPDDTMHNPSGSPSIPVGATVILRPGESYKNGSIVAVIVPDPLKNEPSMTIKK
CCCEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCCEEEE
LVIDGKLVYLSPLNPRYQSSLLTPECKIVAVAKGVQFNL
EEECCEEEEECCCCCHHHHCCCCCCEEEEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157923; 12193633 [H]