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The map label for this gene is yrfF

Identifier: 209400230

GI number: 209400230

Start: 4341743

End: 4343878

Strand: Direct

Name: yrfF

Synonym: ECH74115_4703

Alternate gene names: 209400230

Gene position: 4341743-4343878 (Clockwise)

Preceding gene: 209398170

Following gene: 209400928

Centisome position: 77.92

GC content: 53.09

Gene sequence:

>2136_bases
ATGAGCACCATTGTGATTTTTTTAGCTGCTTTGCTGGCCTGCTCACTACTTGCGGGATGGCTGATAAAAGTGCGATCCAG
ACGGCGTCAGCTGCCCTGGACCAACGCCTTCGCGGATGCGCAAACGCGTAAACTCACACCTGAAGAACGTAGCGCCGTTG
AAAATTATCTTGAGAGCCTGACGCAGGTATTACAGGTGCCTGGCCCAACGGGAGCCAGCGCGGCACCGATCTCTCTGGCG
CTGAATGCCGAAAGCAACAACGTCATGATGCTGACACACGCTATCACGCGTTACGGCATCTCTACCGACGATCCGAATAA
ATGGCGTTACTACCTCGATTCGGTAGAAGTCCACCTGCCCCCTTTCTGGGAGCAGTACATCAACGATGAGAATACCGTTG
AACTGATTCATACCGATTCGCTGCCGCTGGTTATTTCACTCAACGGTCATACGCTGCAGGAGTACATGCAGGAAACTCGC
GGCTATGCCTTGCAACCTGTTCCGTCCACGCAGGCGTCGATTCGCGGGGAAGAGAGTGAGCAAATCGAGCTACTCAATAT
TCGCAAAGAAACGCATGAAGAATATGCGCTGAGTCGTCCGCGCGGGCTGCGTGAAGCGTTGCTGATCGTCGCCTCCTTCC
TGATGTTCTTTTTCTGCCTGATTACCCCGGATGTATTTGTTCCGTGGCTGGCAGGCGGCGCGTTACTGCTGCTGGGCGCA
GGTCTGTGGGGGCTATTCGCCCCCCCGGCAAAATCCTCCCTGCGGGAAATTCATTGTCTGCGCGGTACACCCCGTCGTTG
GGGATTGTTTGGCGAAAACGATCAGGAACAGATCAACAATATTTCACTCGGTATTATCGACCTGGTCTATCCCGCACACT
GGCAGCCATACATTGCTCAGGATCTCGGTCAACAAACCGATATTGATATCTATCTCGACCGCCACCTAGTGCGTCAGGGG
CGATATCTTTCGCTGCATGATGAAGTAAAAAACTTTCCGTTACAGCACTGGCTGCGCAGTACGATTATCGCTGCGGGCTC
GCTGCTGGTGCTGTTTATGCTGTTATTCTGGATCCCGCTGGATATGCCGCTGAAATTCACTCTCTCATGGATGAAAGGTG
CGCAGACCATTGAAGCCACCAGCGTAAAACAACTGGCTGACGCTGGCGTGCGGGTAGGCGATACATTGCGTATTAGCGGT
ACGGGAATGTGTAATATTCGCACTTCCGGAACCTGGAGCGCGAAAACCAATTCACCTTTTTTACCGTTTGACTGCTCGCA
GATCATCTGGAACGACGCCCGCTCATTACCATTACCAGAATCTGAACTGGTCAACAAAGCGACGGCATTGACTGAAGCAG
TTAATCGCCAGCTGCACCCTAAACCGGAAGATGAATCTCGCGTCAGCGCCTCATTACGTTCAGCAATTCAAAAATCCGGC
ATGGTATTGCTTGATGATTTTGGCGACATTGTACTGAAGACAGCGGATCTGTGTTCTGCCAAAGATGACTGTGTGCGACT
GAAAAATGCGCTGGTCAATCTCGGCAACAGTAAAGACTGGGACGCGCTGGTAAAACGCGCCAACGCCGGGAAGCTCGATG
GCGTGAATGTGTTATTACGCCCGGTGAGTGCGGAATCGCTGGATAACCTGGTGGCAACCTCCACCGCGCCGTTTATCACG
CATGAAACGGCGCGAGCGGCACAATCACTAAACAGTCCGGCCCCCGGCGGATTCCTGATTGTCAGCGACGAAGGCAGCGA
TTTTGTTGATCAGCCCTGGCCTTCGGCATCACTTTACGACTACCCGCCGCAAGAACAGTGGAACGCTTTCCAGAAACTGG
CACAAATGCTGATGCATACGCCGTTTAACGCCGAGGGTATCGTCACAAAAATCTTCACTGACGCCAATGGTACGCAGCAT
ATAGGCCTTCATCCGATCCCGGATCGTTCCGGCCTGTGGCGCTATCTCAGCACCACGCTGCTGCTACTGACGATGCTGGG
TAGCGCCATTTATAATGGCGTACAGGCCTGGCGGCGTTACCAGCGTCATCGCACTCGCATGATGAAGATTCAGGCCTATT
ATGAAAGCTGCCTGAACCCGCAACTGATCACCCCTTCAGAAAGCCTTATCGAATAA

Upstream 100 bases:

>100_bases
TCAAGTTAAACTCCACGCTTGCCGATAGCCAACCGCAGAATCATGTATTGTGTCCGGTGCGACTGACCACGCCTGACAGA
CTAAGTAAGATGGGGAAAGC

Downstream 100 bases:

>100_bases
CACGTTTGCGCGGCAGGTTATGCTACCCTGTCGCGCAAATTGCTTCACTCTGGAGATTTTCCTCATGCATATCAACATTG
CCTGGCAGGACGTAGATACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 711; Mature: 710

Protein sequence:

>711_residues
MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRKLTPEERSAVENYLESLTQVLQVPGPTGASAAPISLA
LNAESNNVMMLTHAITRYGISTDDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQETR
GYALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFFCLITPDVFVPWLAGGALLLLGA
GLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQEQINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHLVRQG
RYLSLHDEVKNFPLQHWLRSTIIAAGSLLVLFMLLFWIPLDMPLKFTLSWMKGAQTIEATSVKQLADAGVRVGDTLRISG
TGMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATALTEAVNRQLHPKPEDESRVSASLRSAIQKSG
MVLLDDFGDIVLKTADLCSAKDDCVRLKNALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFIT
HETARAAQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNAEGIVTKIFTDANGTQH
IGLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQRHRTRMMKIQAYYESCLNPQLITPSESLIE

Sequences:

>Translated_711_residues
MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRKLTPEERSAVENYLESLTQVLQVPGPTGASAAPISLA
LNAESNNVMMLTHAITRYGISTDDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQETR
GYALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFFCLITPDVFVPWLAGGALLLLGA
GLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQEQINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHLVRQG
RYLSLHDEVKNFPLQHWLRSTIIAAGSLLVLFMLLFWIPLDMPLKFTLSWMKGAQTIEATSVKQLADAGVRVGDTLRISG
TGMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATALTEAVNRQLHPKPEDESRVSASLRSAIQKSG
MVLLDDFGDIVLKTADLCSAKDDCVRLKNALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFIT
HETARAAQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNAEGIVTKIFTDANGTQH
IGLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQRHRTRMMKIQAYYESCLNPQLITPSESLIE
>Mature_710_residues
STIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRKLTPEERSAVENYLESLTQVLQVPGPTGASAAPISLAL
NAESNNVMMLTHAITRYGISTDDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQETRG
YALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFFCLITPDVFVPWLAGGALLLLGAG
LWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQEQINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHLVRQGR
YLSLHDEVKNFPLQHWLRSTIIAAGSLLVLFMLLFWIPLDMPLKFTLSWMKGAQTIEATSVKQLADAGVRVGDTLRISGT
GMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATALTEAVNRQLHPKPEDESRVSASLRSAIQKSGM
VLLDDFGDIVLKTADLCSAKDDCVRLKNALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFITH
ETARAAQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNAEGIVTKIFTDANGTQHI
GLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQRHRTRMMKIQAYYESCLNPQLITPSESLIE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the igaA family

Homologues:

Organism=Escherichia coli, GI1789801, Length=711, Percent_Identity=99.57805907173, Blast_Score=1460, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IGAA_ECO57 (P58720)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   F86004
- PIR:   H91158
- RefSeq:   NP_289937.1
- RefSeq:   NP_312267.1
- EnsemblBacteria:   EBESCT00000025137
- EnsemblBacteria:   EBESCT00000058611
- GeneID:   915906
- GeneID:   959306
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4752
- KEGG:   ecs:ECs4240
- GeneTree:   EBGT00050000010175
- HOGENOM:   HBG417125
- OMA:   ISLNGHS
- ProtClustDB:   CLSK880647
- BioCyc:   ECOL83334:ECS4240-MONOMER
- InterPro:   IPR010771
- ProDom:   PD147088

Pfam domain/function: PF07095 IgaA

EC number: NA

Molecular weight: Translated: 79474; Mature: 79343

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x120748fc)-; HASH(0x1182c238)-; HASH(0x11b9ef8c)-; HASH(0x11de8a88)-; HASH(0x10703740)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRKLTPEERSAVENYLESL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHH
TQVLQVPGPTGASAAPISLALNAESNNVMMLTHAITRYGISTDDPNKWRYYLDSVEVHLP
HHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHCCCCCCCCCCCEEEEECEEEECC
PFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQETRGYALQPVPSTQASIRGEESE
CHHHHHCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHCCCEECCCCCCHHHCCCCCCC
QIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFFCLITPDVFVPWLAGGALLLLGA
CEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHH
GLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQEQINNISLGIIDLVYPAHWQPYIAQ
HHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHCCCEEHHEECCCCCCCCHHHH
DLGQQTDIDIYLDRHLVRQGRYLSLHDEVKNFPLQHWLRSTIIAAGSLLVLFMLLFWIPL
HCCCCCCEEEEECHHHHHCCCEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DMPLKFTLSWMKGAQTIEATSVKQLADAGVRVGDTLRISGTGMCNIRTSGTWSAKTNSPF
CCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCC
LPFDCSQIIWNDARSLPLPESELVNKATALTEAVNRQLHPKPEDESRVSASLRSAIQKSG
CCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
MVLLDDFGDIVLKTADLCSAKDDCVRLKNALVNLGNSKDWDALVKRANAGKLDGVNVLLR
CEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEEEE
PVSAESLDNLVATSTAPFITHETARAAQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYD
CCCHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCC
YPPQEQWNAFQKLAQMLMHTPFNAEGIVTKIFTDANGTQHIGLHPIPDRSGLWRYLSTTL
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEECCCCCCCCCCHHHHHHHHHH
LLLTMLGSAIYNGVQAWRRYQRHRTRMMKIQAYYESCLNPQLITPSESLIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHCH
>Mature Secondary Structure 
STIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRKLTPEERSAVENYLESL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHH
TQVLQVPGPTGASAAPISLALNAESNNVMMLTHAITRYGISTDDPNKWRYYLDSVEVHLP
HHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHCCCCCCCCCCCEEEEECEEEECC
PFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQETRGYALQPVPSTQASIRGEESE
CHHHHHCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHCCCEECCCCCCHHHCCCCCCC
QIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFFCLITPDVFVPWLAGGALLLLGA
CEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHH
GLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQEQINNISLGIIDLVYPAHWQPYIAQ
HHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHCCCEEHHEECCCCCCCCHHHH
DLGQQTDIDIYLDRHLVRQGRYLSLHDEVKNFPLQHWLRSTIIAAGSLLVLFMLLFWIPL
HCCCCCCEEEEECHHHHHCCCEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DMPLKFTLSWMKGAQTIEATSVKQLADAGVRVGDTLRISGTGMCNIRTSGTWSAKTNSPF
CCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCC
LPFDCSQIIWNDARSLPLPESELVNKATALTEAVNRQLHPKPEDESRVSASLRSAIQKSG
CCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
MVLLDDFGDIVLKTADLCSAKDDCVRLKNALVNLGNSKDWDALVKRANAGKLDGVNVLLR
CEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEEEE
PVSAESLDNLVATSTAPFITHETARAAQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYD
CCCHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCC
YPPQEQWNAFQKLAQMLMHTPFNAEGIVTKIFTDANGTQHIGLHPIPDRSGLWRYLSTTL
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEECCCCCCCCCCHHHHHHHHHH
LLLTMLGSAIYNGVQAWRRYQRHRTRMMKIQAYYESCLNPQLITPSESLIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796