Click here to switch to the map view.

The map label for this gene is treC [H]

Identifier: 209400031

GI number: 209400031

Start: 5393775

End: 5395430

Strand: Reverse

Name: treC [H]

Synonym: ECH74115_5761

Alternate gene names: 209400031

Gene position: 5395430-5393775 (Counterclockwise)

Preceding gene: 209399645

Following gene: 209399416

Centisome position: 96.83

GC content: 53.14

Gene sequence:

>1656_bases
ATGACTAATCTTCCCCACTGGTGGCAAAACGGCGTTATCTACCAGATTTATCCAAAGAGTTTTCAGGACACCACGGGTAG
CGGCACCGGCGATTTACGTGGCGTTATCCAACGCCTGGACTATCTGCATAAACTGGGCGTTGATGCCATCTGGCTAACCC
CCTTTTATGTCTCTCCGCAGGTCGATAACGGTTACGATGTAGCGAACTATACGGCGATTGATCCCACCTACGGCACGCTG
GACGATTTTGACGAACTGGTGACGCAGGCAAAATCGCGCGGGATTCGTATCATTCTCGATATGGTGTTTAACCATACCTC
TACCCAACATGCCTGGTTTCGCGAGGCGCTGAACAAAGAAAGCCCTTACCGCCAGTTTTATATCTGGCGCGATGGCGAAC
CAGAAACGCCACCGAACAACTGGCGTTCAAAATTTGGCGGTAGTGCGTGGCGCTGGCATGCGGAAAGCGAACAGTACTAT
TTGCATCTCTTTGCACCAGAACAGGCGGATCTCAACTGGGAGAATCCAGCGGTACGCGCAGAGCTGAAAAAAGTCTGTGA
GTTCTGGGCCGATCGTGGGGTCGACGGGTTGCGCCTGGATGTGGTGAATCTGATCTCCAAAGACCCGCGTTTCCCTGATG
ACCTGGATGGCGACGGGCGTCGCTTCTACACCGACGGGCCACGAGCACACGAGTTTTTGCACGAGATGAACCGCGATGTG
TTTACGCCACGCGGGTTAATGACCGTAGGTGAAATGTCCTCCACCAGCCTTGAGCATTGCCAGCGATACGCGGCACTGAC
AGGCAGTGAATTGTCGATGACCTTTAATTTTCATCACCTGAAGGTCGATTATCCCGGTGGTGAAAAATGGACGCTGGCTA
AACCTGACTTTGTGGCGTTGAAAACATTGTTCCGCCACTGGCAACAAGGAATGCACAACGTAGCATTGAATGCCTTGTTC
TGGTGTAACCACGATCAGCCGCGCATTGTTTCTCGCTTTGGTGATGAAGGTGAATACCGCGTGCCTGCGGCAAAAATGCT
GGCGATGGTGCTGCATGGCATGCAGGGAACGCCGTATATCTACCAGGGCGAAGAGATTGGCATGACCAACCCGCATTTCA
CGCGCATTACTGACTATCGCGACGTAGAGAGCCTCAATATGTTTGCCGAGCTGCGCAACGATGGGCGTGATGCCGACGAG
TTATTGGCAATCCTCGCCAGTAAATCCCGTGACAACAGCCGCACGCCCATGCAATGGAGCAACGGCGATAATGCCGGGTT
TACGGCTGGCGAACCGTGGATTGGCCTGGGCGATAACTATCAACAAATCAACGTAGAAGCCGCGCTGGCCGATGAGTCCT
CGGTGTTTTACACCTACCAAAAGTTAATCGCACTGCGTAAGCAGGAAGCCATCCTGACATGGGGCAATTACCAGGATCTG
CTGCCAAACAGCCCTGTATTGTGGTGCTATCGCCGTGAATGGAAGGGGCAAACCTTGCTGGTCATTGCCAACCTTAGCCG
TGAGATCCAACCCTGGCAGCTAGGGCAAATGCGCGGCAACTGGCAGCTTGTGATGCATAACTACGAAGAAGCCTCACCAC
AACCCTGTGCCATGACTTTACGGCCTTTTGAGGCTGTCTGGTGGTTACAGAAGTAA

Upstream 100 bases:

>100_bases
TCGTTTATCTATCAGCGGAAATACCGCCTGGGCACGCTGGACATTGTTTAATTTTCTTCGGGGCGCAATTGCGCCCCCTC
GCATTTGCAGGAATAACGTA

Downstream 100 bases:

>100_bases
ATCTTCCCTAAGCCCCGGTAATGCCGGTCATTCCGGGGTTTTGTCTGTCAGCATGTTGTTTTTGTTGATTTTTCAACCAG
CAAATTCATTAAAAAATTTA

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MTNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTL
DDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPDDLDGDGRRFYTDGPRAHEFLHEMNRDV
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVALNALF
WCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADE
LLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALADESSVFYTYQKLIALRKQEAILTWGNYQDL
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQLGQMRGNWQLVMHNYEEASPQPCAMTLRPFEAVWWLQK

Sequences:

>Translated_551_residues
MTNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTL
DDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPDDLDGDGRRFYTDGPRAHEFLHEMNRDV
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVALNALF
WCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADE
LLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALADESSVFYTYQKLIALRKQEAILTWGNYQDL
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQLGQMRGNWQLVMHNYEEASPQPCAMTLRPFEAVWWLQK
>Mature_550_residues
TNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTLD
DFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYYL
HLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPDDLDGDGRRFYTDGPRAHEFLHEMNRDVF
TPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVALNALFW
CNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADEL
LAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALADESSVFYTYQKLIALRKQEAILTWGNYQDLL
PNSPVLWCYRREWKGQTLLVIANLSREIQPWQLGQMRGNWQLVMHNYEEASPQPCAMTLRPFEAVWWLQK

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=524, Percent_Identity=29.7709923664122, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI65506891, Length=108, Percent_Identity=36.1111111111111, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI61744479, Length=108, Percent_Identity=36.1111111111111, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI61744483, Length=108, Percent_Identity=36.1111111111111, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI61744481, Length=108, Percent_Identity=36.1111111111111, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI61744475, Length=107, Percent_Identity=36.4485981308411, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI61744477, Length=107, Percent_Identity=36.4485981308411, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1790687, Length=551, Percent_Identity=98.7295825771325, Blast_Score=1140, Evalue=0.0,
Organism=Escherichia coli, GI1786604, Length=188, Percent_Identity=31.3829787234043, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789995, Length=137, Percent_Identity=32.8467153284672, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25147709, Length=495, Percent_Identity=26.8686868686869, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32565753, Length=528, Percent_Identity=23.1060606060606, Blast_Score=112, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6321726, Length=576, Percent_Identity=36.1111111111111, Blast_Score=356, Evalue=6e-99,
Organism=Saccharomyces cerevisiae, GI6322245, Length=578, Percent_Identity=36.3321799307958, Blast_Score=355, Evalue=1e-98,
Organism=Saccharomyces cerevisiae, GI6324416, Length=576, Percent_Identity=36.4583333333333, Blast_Score=343, Evalue=5e-95,
Organism=Saccharomyces cerevisiae, GI6322241, Length=576, Percent_Identity=36.4583333333333, Blast_Score=343, Evalue=5e-95,
Organism=Saccharomyces cerevisiae, GI6322021, Length=576, Percent_Identity=36.4583333333333, Blast_Score=343, Evalue=5e-95,
Organism=Saccharomyces cerevisiae, GI6321731, Length=589, Percent_Identity=35.4838709677419, Blast_Score=333, Evalue=3e-92,
Organism=Saccharomyces cerevisiae, GI6319776, Length=589, Percent_Identity=35.3140916808149, Blast_Score=332, Evalue=7e-92,
Organism=Drosophila melanogaster, GI24583745, Length=537, Percent_Identity=36.1266294227188, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI221330053, Length=499, Percent_Identity=37.4749498997996, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24583747, Length=552, Percent_Identity=35.5072463768116, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24583749, Length=552, Percent_Identity=35.5072463768116, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24586599, Length=578, Percent_Identity=32.0069204152249, Blast_Score=286, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24586597, Length=532, Percent_Identity=34.2105263157895, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24586587, Length=503, Percent_Identity=33.5984095427435, Blast_Score=274, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24586593, Length=531, Percent_Identity=32.5800376647834, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI45549022, Length=541, Percent_Identity=33.826247689464, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24586589, Length=546, Percent_Identity=32.7838827838828, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24586591, Length=494, Percent_Identity=33.1983805668016, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI281360393, Length=477, Percent_Identity=29.979035639413, Blast_Score=199, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 63790; Mature: 63659

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQ
CCCCCCHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKE
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEHHHCCCCCHHHHHHHHHCCC
SPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYYLHLFAPEQADLNWENPAVRA
CCCEEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHH
ELKKVCEFWADRGVDGLRLDVVNLISKDPRFPDDLDGDGRRFYTDGPRAHEFLHEMNRDV
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCC
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVAL
CCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCEEEECCCCHHHH
KTLFRHWQQGMHNVALNALFWCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYI
HHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCEE
YQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADELLAILASKSRDNSRTPMQWS
EECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEC
NGDNAGFTAGEPWIGLGDNYQQINVEAALADESSVFYTYQKLIALRKQEAILTWGNYQDL
CCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCHHH
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQLGQMRGNWQLVMHNYEEASPQPCAMTL
CCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEE
RPFEAVWWLQK
CCCHHEEEECC
>Mature Secondary Structure 
TNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQ
CCCCCHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKE
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEHHHCCCCCHHHHHHHHHCCC
SPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYYLHLFAPEQADLNWENPAVRA
CCCEEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHH
ELKKVCEFWADRGVDGLRLDVVNLISKDPRFPDDLDGDGRRFYTDGPRAHEFLHEMNRDV
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCC
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVAL
CCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCEEEECCCCHHHH
KTLFRHWQQGMHNVALNALFWCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYI
HHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCEE
YQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADELLAILASKSRDNSRTPMQWS
EECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEC
NGDNAGFTAGEPWIGLGDNYQQINVEAALADESSVFYTYQKLIALRKQEAILTWGNYQDL
CCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCHHH
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQLGQMRGNWQLVMHNYEEASPQPCAMTL
CCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEE
RPFEAVWWLQK
CCCHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083158; 7610040; 9278503; 8421692 [H]