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The map label for this gene is yfgC

Identifier: 209399555

GI number: 209399555

Start: 3436354

End: 3437817

Strand: Direct

Name: yfgC

Synonym: ECH74115_3716

Alternate gene names: 209399555

Gene position: 3436354-3437817 (Clockwise)

Preceding gene: 209397824

Following gene: 209397583

Centisome position: 61.67

GC content: 53.96

Gene sequence:

>1464_bases
ATGTTCAGGCAGTTGAAAAAAAACCTGGTTGCAACCCTCATTGCTGCTATGACCATTGGTCAGGTAGCCCCGGCATTTGC
CGACAGCGCAGACACCTTGCCGGATATGGGAACCTCCGCAGGAAGCACGCTTTCCATTGGTCAGGAAATGCAGATGGGCG
ACTATTATGTCCGCCAGCTACGCGGCAGCGCGCCGTTAATTAATGACCCGCTGTTAACGCAATATATTAATTCGCTGGGG
ATGCGTCTGGTTTCGCATGCCAATTCGGTTAAGACACCGTTTCATTTCTTTCTGATCAACAACGACGAAATTAACGCCTT
TGCTTTCTTTGGCGGCAACGTGGTGCTGCACTCTGCCCTGTTCCGTTATTCCGATAACGAAAGTCAACTGGCTTCAGTTA
TGGCGCACGAAATCTCCCACGTCACCCAACGTCACCTGGCGCGAGCGATGGAAGATCAGCAGCGCAACGCGCCGCTGACC
TGGGTCGGCGCGTTAGGTTCTATTTTACTGGCGATGGCCAGTCCGCAGGCGGGGATGGCGGCGCTGACCGGTACACTGGC
GGGAACGCGTCAGGGGATGATCAGTTTCACCCAGCAAAATGAACAGGAAGCGGACCGCATTGGTATTCAGGTGCTGCAAC
GCTCGGGATTCGATCCGCAGGCGATGCCAACCTTCCTCGAAAAATTACTCGATCAGGCGCGTTACTCCTCGCGCCCGCCG
GAAATTTTACTGACTCACCCGTTGCCGGAAAGTCGTCTGGCAGATGCCCGCAACCGTGCTAATCAGATGCGCCCGATGGT
GGTGCAGTCGTCGGAAGATTTCTATCTGGCGAAAGCGCGCACACTGGGGATGTATAATTCCGGACGTAACCAGCTCACCA
GTGATTTGCTGGATGAATGGGCGAAAGGAAACGTTCGTCAGCAACGAGCGGCGCAATATGGTCGTGCTTTACAGGCGATG
GAAGCCAATAAATACGACGAGGCGCGAAAAACGCTGCAACCGTTACTGGCGGCAGAACCTGGCAACGCATGGTATCTCGA
TCTGGCTACTGATATCGATCTTGGGCAAAACAAAGCCAATGAGGCGATCAATCGTCTGAAAAATGCCCGCGATTTGCGCA
CCAATCCTGTGTTGCAGCTCAACCTGGCGAACGCTTATCTACAAGGCGGTCAACCACAAGAAGCGGCCAATATTCTTAAT
CGCTACACCTTTAATAATAAAGATGACAGCAACGGCTGGGATTTGCTGGCACAGGCGGAAGCCGCGCTAAATAACCGCGA
TCAGGAGCTGGCTGCGCGAGCAGAAGGTTATGCGCTCGCCGGACGACTCGATCAGGCCATTTCGCTGTTGAGTAGCGCCA
GTTCGCAGGTGAAATTAGGCAGCCTGCAACAAGCGCGTTACGATGCGCGCATCGACCAGTTGCGCCAGCTGCAGGAACGC
TTTAAGCCTTATACCAAGATGTAA

Upstream 100 bases:

>100_bases
GTGGGCTAATCTTCGCCGTTACACTCAAAGGCGGCGCGGTGGGAACGATATTTCACAGTATCGGTCAAATGACTATCTTC
AGAAATACAGGATAGAGGTT

Downstream 100 bases:

>100_bases
TTCGCATTAAAGGAAGAACAATGACCAAACAGGTAAAAATCTACCATAACCCACGCTGTTCAAAGAGCCGGGAAACGCTG
AACCTGCTGAAAGAAAACGG

Product: peptidase, M48 family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTLSIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLG
MRLVSHANSVKTPFHFFLINNDEINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRNAPLT
WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFDPQAMPTFLEKLLDQARYSSRPP
EILLTHPLPESRLADARNRANQMRPMVVQSSEDFYLAKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAM
EANKYDEARKTLQPLLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQPQEAANILN
RYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLLSSASSQVKLGSLQQARYDARIDQLRQLQER
FKPYTKM

Sequences:

>Translated_487_residues
MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTLSIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLG
MRLVSHANSVKTPFHFFLINNDEINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRNAPLT
WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFDPQAMPTFLEKLLDQARYSSRPP
EILLTHPLPESRLADARNRANQMRPMVVQSSEDFYLAKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAM
EANKYDEARKTLQPLLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQPQEAANILN
RYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLLSSASSQVKLGSLQQARYDARIDQLRQLQER
FKPYTKM
>Mature_487_residues
MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTLSIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLG
MRLVSHANSVKTPFHFFLINNDEINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRNAPLT
WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFDPQAMPTFLEKLLDQARYSSRPP
EILLTHPLPESRLADARNRANQMRPMVVQSSEDFYLAKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAM
EANKYDEARKTLQPLLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQPQEAANILN
RYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLLSSASSQVKLGSLQQARYDARIDQLRQLQER
FKPYTKM

Specific function: Unknown

COG id: COG4783

COG function: function code R; Putative Zn-dependent protease, contains TPR repeats

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats

Homologues:

Organism=Escherichia coli, GI1788840, Length=487, Percent_Identity=99.7946611909651, Blast_Score=990, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YFGC_ECO57 (Q8XAD2)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   D91048
- PIR:   H85892
- RefSeq:   NP_289047.1
- RefSeq:   NP_311383.1
- ProteinModelPortal:   Q8XAD2
- SMR:   Q8XAD2
- EnsemblBacteria:   EBESCT00000027156
- EnsemblBacteria:   EBESCT00000055198
- GeneID:   915227
- GeneID:   957750
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3757
- KEGG:   ecs:ECs3356
- GeneTree:   EBGT00050000009224
- HOGENOM:   HBG701418
- OMA:   LSQRHFA
- ProtClustDB:   CLSK874698
- BioCyc:   ECOL83334:ECS3356-MONOMER
- GO:   GO:0016020
- GO:   GO:0005488
- GO:   GO:0006508
- InterPro:   IPR001915
- InterPro:   IPR011990
- Gene3D:   G3DSA:1.25.40.10

Pfam domain/function: PF01435 Peptidase_M48

EC number: NA

Molecular weight: Translated: 53936; Mature: 53936

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS50005 TPR; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTLSIGQEMQMGDYYVRQL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINNDEINAFAFFGGNVVLHSAL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCHHHHHHHH
FRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRNAPLTWVGALGSILLAMASPQAGMA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCCHH
ALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFDPQAMPTFLEKLLDQARYSSRPP
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
EILLTHPLPESRLADARNRANQMRPMVVQSSEDFYLAKARTLGMYNSGRNQLTSDLLDEW
CEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEHHHHHCCCCCCHHHHHHHHHHHH
AKGNVRQQRAAQYGRALQAMEANKYDEARKTLQPLLAAEPGNAWYLDLATDIDLGQNKAN
HCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHH
EAINRLKNARDLRTNPVLQLNLANAYLQGGQPQEAANILNRYTFNNKDDSNGWDLLAQAE
HHHHHHHHHHHCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
AALNNRDQELAARAEGYALAGRLDQAISLLSSASSQVKLGSLQQARYDARIDQLRQLQER
HHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FKPYTKM
HCCCCCC
>Mature Secondary Structure
MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTLSIGQEMQMGDYYVRQL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINNDEINAFAFFGGNVVLHSAL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCHHHHHHHH
FRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRNAPLTWVGALGSILLAMASPQAGMA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCCHH
ALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFDPQAMPTFLEKLLDQARYSSRPP
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
EILLTHPLPESRLADARNRANQMRPMVVQSSEDFYLAKARTLGMYNSGRNQLTSDLLDEW
CEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEHHHHHCCCCCCHHHHHHHHHHHH
AKGNVRQQRAAQYGRALQAMEANKYDEARKTLQPLLAAEPGNAWYLDLATDIDLGQNKAN
HCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHH
EAINRLKNARDLRTNPVLQLNLANAYLQGGQPQEAANILNRYTFNNKDDSNGWDLLAQAE
HHHHHHHHHHHCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
AALNNRDQELAARAEGYALAGRLDQAISLLSSASSQVKLGSLQQARYDARIDQLRQLQER
HHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FKPYTKM
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796