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The map label for this gene is ilvH [H]

Identifier: 209399406

GI number: 209399406

Start: 91913

End: 92434

Strand: Direct

Name: ilvH [H]

Synonym: ECH74115_0087

Alternate gene names: 209399406

Gene position: 91913-92434 (Clockwise)

Preceding gene: 209398207

Following gene: 209399285

Centisome position: 1.65

GC content: 49.04

Gene sequence:

>522_bases
GTGGTTAAGCAAAACGGAGAGAACCTGATTATGCGCCGGATATTATCAGTCTTACTCGAAAATGAATCAGGCGCGTTATC
CCGCGTGATTGGCCTTTTTTCCCAGCGTGGCTACAACATTGAAAGCCTGACCGTTGCGCCAACCGACGATCCGACATTAT
CGCGTATGACCATCCAGACCGTGGGCGATGAAAAAGTGCTTGAGCAGATCGAAAAGCAATTATACAAGCTGGTCGATGTC
TTGCGCGTGAGTGAGTTGGGGCAGGGCGCGCATGTTGAGAGGGAAATCATGCTGGTGAAAATTCAGGCCAGCGGTTACGG
GCGTGACGAAGTTAAACGTAATACGGAAATATTCCGTGGGCAAATTATTGATGTCACACCCTCGCTTTATACCGTTCAAT
TAGCAGGCACCAGCGATAAGCTTGATGCATTTTTAGCATCGATTCGCGATGTGGCGAAAATTGTGGAAGTTGCTCGCTCT
GGTGTGGTCGGACTTTCGCGCGGCGATAAAATAATGCGTTGA

Upstream 100 bases:

>100_bases
AACAGGTGCGTAATAATCGCCTGGTATTTGTTGATGTCACCGTCGATGGCAGTGAGCACGTCTACCCGATGCAGATTCGC
GGGGGCGGAATGGATGAAAT

Downstream 100 bases:

>100_bases
GAATGATCTCAATGCGCAATTTACAGCCCAACATGTCACGTTGGGCTTTTTTTGCGAAATCAGTGGGAACCTGGAATAAA
AGCAGTTGCCGCAGTTAATT

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: ALS-III; Acetohydroxy-acid synthase III small subunit; AHAS-III [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MVKQNGENLIMRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDEKVLEQIEKQLYKLVDV
LRVSELGQGAHVEREIMLVKIQASGYGRDEVKRNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARS
GVVGLSRGDKIMR

Sequences:

>Translated_173_residues
MVKQNGENLIMRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDEKVLEQIEKQLYKLVDV
LRVSELGQGAHVEREIMLVKIQASGYGRDEVKRNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARS
GVVGLSRGDKIMR
>Mature_173_residues
MVKQNGENLIMRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDEKVLEQIEKQLYKLVDV
LRVSELGQGAHVEREIMLVKIQASGYGRDEVKRNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARS
GVVGLSRGDKIMR

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=163, Percent_Identity=98.7730061349693, Blast_Score=318, Evalue=9e-89,
Organism=Saccharomyces cerevisiae, GI6319837, Length=205, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 19189; Mature: 19189

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKQNGENLIMRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQT
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHEEEEE
VGDEKVLEQIEKQLYKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVKRNTEIFRG
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCC
QIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDKIMR
EEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
>Mature Secondary Structure
MVKQNGENLIMRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQT
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHEEEEE
VGDEKVLEQIEKQLYKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVKRNTEIFRG
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCC
QIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDKIMR
EEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6308579; 1630901; 9278503; 1851954; 2198273 [H]