Click here to switch to the map view.

The map label for this gene is ygfA [H]

Identifier: 209399336

GI number: 209399336

Start: 3897713

End: 3898315

Strand: Direct

Name: ygfA [H]

Synonym: ECH74115_4205

Alternate gene names: 209399336

Gene position: 3897713-3898315 (Clockwise)

Preceding gene: 209397387

Following gene: 209400353

Centisome position: 69.95

GC content: 51.58

Gene sequence:

>603_bases
ATGACGCAACTACCAGAACTCCCACTGACATTATCCCGACAAGAAATCCGCAAAATGATTCGGCAACGTCGTCGTGCGTT
AACGCCGGAACAACAGCAGGAAATGGGTCAACAAGCCGCTACCCGGATGATGACTTATCCCCCGGTGGTGATGGCGCATA
CGGTCGCTGTATTCCTCTCTTTTGATGGTGAACTCGACACCCAGCCGCTTATAGAACAACTCTGGCGCGCCGGTAAGCGC
GTATATCTTCCAGTTTTGCATCCCTTTAGTGCCGGTAATTTGCTGTTCCTGAATTACCATCCGCAAAGCGAACTGGTGAT
GAACAGGTTGAAAATCCATGAGCCAAAACTGGATGTGCGTGACGTGCTCCCCCTTTCCCGATTAGACGTGCTGATCACAC
CGCTGGTCGCCTTTGATGAGTACGGTCAGCGCCTGGGAATGGGCGGTGGTTTTTATGATCGGACCTTACAAAACTGGCAG
CACTATAAAACGCAACCGGTGGGTTATGCGCATGATTGTCAGTTGGTGGAAAAACTCCCCGTTGAAGAGTGGGATATCCC
TCTTCCTGCGGTGGTTACACCGTCGAAAGTCTGGGAGTGGTAA

Upstream 100 bases:

>100_bases
AGCCTTAAAACTGCGACGACACATTCACCTTGAACCAAGGGTTCAAGGGTTACAGCCTGCGGCGGCATCTCGGAGATTCC
CTTCTTATCTGGCACCAGCC

Downstream 100 bases:

>100_bases
GGGCGATACACCTGCATCGCCCTGATTGACATCGTTGATTCTTTAACCTAATTTAGTGAGTAAGGGTAAGGGAGGATGAC
TCCTCCCCTGAGACTGACTG

Product: putative ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMMTYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKR
VYLPVLHPFSAGNLLFLNYHPQSELVMNRLKIHEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQ
HYKTQPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW

Sequences:

>Translated_200_residues
MTQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMMTYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKR
VYLPVLHPFSAGNLLFLNYHPQSELVMNRLKIHEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQ
HYKTQPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW
>Mature_199_residues
TQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMMTYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRV
YLPVLHPFSAGNLLFLNYHPQSELVMNRLKIHEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQH
YKTQPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=192, Percent_Identity=24.4791666666667, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1789278, Length=182, Percent_Identity=100, Blast_Score=377, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17510857, Length=193, Percent_Identity=23.8341968911917, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI161077430, Length=189, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 23241; Mature: 23110

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMMTYPPVVMAHTVAVFLS
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
FDGELDTQPLIEQLWRAGKRVYLPVLHPFSAGNLLFLNYHPQSELVMNRLKIHEPKLDVR
CCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCHH
DVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQHYKTQPVGYAHDCQLVEKLP
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
VEEWDIPLPAVVTPSKVWEW
CCCCCCCCCCEECCHHHCCC
>Mature Secondary Structure 
TQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMMTYPPVVMAHTVAVFLS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
FDGELDTQPLIEQLWRAGKRVYLPVLHPFSAGNLLFLNYHPQSELVMNRLKIHEPKLDVR
CCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCHH
DVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQHYKTQPVGYAHDCQLVEKLP
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
VEEWDIPLPAVVTPSKVWEW
CCCCCCCCCCEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]