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The map label for this gene is tldD [H]

Identifier: 209398830

GI number: 209398830

Start: 4227584

End: 4229029

Strand: Reverse

Name: tldD [H]

Synonym: ECH74115_4561

Alternate gene names: 209398830

Gene position: 4229029-4227584 (Counterclockwise)

Preceding gene: 209398580

Following gene: 209399458

Centisome position: 75.9

GC content: 54.7

Gene sequence:

>1446_bases
ATGAGTCTTAACCTGGTAAGTGAACAATTGCTAGCGGCGAACGGCCTGAAACATCAGGACTTGTTCGTGATCCTCGGTCA
ACTGGCCGAACGTCGCCTTGATTATGGCGATCTCTATTTTCAGTCGAGCTATCACGAATCCTGGGTTTTAGAAGACCGCA
TTATTAAAGATGGTTCTTACAACATCGATCAGGGCGTTGGTGTGCGTGCAATCAGCGGTGAAAAAACCGGATTTGCTTAC
GCTGACCAAATCAGCCTGCTGGCGCTGGAACAGAGTGCGCAAGCGGCGCGCACCATCGCCCGTGATAGCGGTGATGGCAA
AGTACAGACGCTGGGCGCGGTAGAGCATAGCCCGTTGTATACCTCGGTAGATCCGCTGCAAAGCATGAGCCGTGAAGAGA
AGCTGGATATCCTGCGTCGCGTCGATAAGGTTGCCCGCGAAGCGGACAAGCGCGTACAGGAAGTGACTGCCAGCCTCAGT
GGTGTCTATGAATTAATTCTGGTTGCGGCCACCGACGGCACGCTAGCGGCGGATGTCCGTCCGCTGGTGCGTCTTTCCGT
GAGCGTTCTGATCGAAGAAGATGGCAAACGCGAACGCGGTGCCAGTGGCGGCGGCGGTCGTTTTGGTTATGAGTTCTTCC
TTGCCGATCTCGACGGCGAAGTCCGTGCGGATGCATGGGCAAAAGAAGCAGTACGTATGGCGCTGGTCAATCTTTCTGCC
GTTGCTGCACCAGCGGGCACCATGCCGGTAGTACTTGGCGCAGGTTGGCCGGGCGTGCTGTTGCATGAAGCGGTAGGTCA
CGGTCTGGAAGGCGACTTCAACCGCCGTGGCACTTCAGTATTTAGTGGACAGGTCGGGGAGCTGGTGGCTTCAGAACTGT
GTACCGTGGTTGATGACGGTACGATGGTCGATCGCCGTGGTTCGGTGGCGATTGATGACGAAGGTACGCCAGGCCAGTAC
AACGTGCTGATTGAGAACGGCATTCTGAAAGGCTACATGCAGGATAAACTCAACGCGCGTTTGATGGGGATGACGCCGAC
TGGCAACGGTCGCCGTGAATCCTACGCCCATCTGCCCATGCCGCGTATGACCAACACCTATATGCTGCCGGGTAAATCGA
CCCCGCAGGAAATTATTGAATCCGTTGAGTACGGTATCTATGCACCGAACTTTGGTGGCGGTCAGGTGGATATCACCTCC
GGCAAATTCGTTTTCTCCACTTCAGAAGCATATCTGATTGAAAACGGTAAAGTAACGAAGCCGGTGAAAGGCGCAACGTT
GATTGGTTCCGGTATCGAAACCATGCAGCAGATTTCGATGGTTGGCAACGACCTGAAACTGGATAACGGCGTGGGTGTCT
GCGGTAAAGAAGGGCAAAGTTTGCCGGTTGGCGTGGGCCAGCCAACGCTGAAAGTTGATAACCTGACTGTTGGCGGTACT
GCGTAA

Upstream 100 bases:

>100_bases
AACGAGCCAGAACATAACCGTAGGCTGGATAGGGCGTTCACGCCGCATCCGGCAGCCGTAAAAAATCCTCTACTGCAGTA
ACTAACGAGTAGCAAAAACG

Downstream 100 bases:

>100_bases
TAATTTCAGTATTTTCAGAAGGATAATTAATCCTTCCTCGTGCACGAACGGTCCCCTCGCCCCTTTGGGGAGAGGGTTAG
GGTGAGGGGAACCCGTTGGC

Product: protease TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSLNLVSEQLLAANGLKHQDLFVILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAY
ADQISLLALEQSAQAARTIARDSGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
GVYELILVAATDGTLAADVRPLVRLSVSVLIEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQY
NVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITS
GKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
A

Sequences:

>Translated_481_residues
MSLNLVSEQLLAANGLKHQDLFVILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAY
ADQISLLALEQSAQAARTIARDSGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
GVYELILVAATDGTLAADVRPLVRLSVSVLIEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQY
NVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITS
GKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
A
>Mature_480_residues
SLNLVSEQLLAANGLKHQDLFVILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYA
DQISLLALEQSAQAARTIARDSGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSG
VYELILVAATDGTLAADVRPLVRLSVSVLIEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSAV
AAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYN
VLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSG
KFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=481, Percent_Identity=99.3762993762994, Blast_Score=969, Evalue=0.0,
Organism=Escherichia coli, GI1790682, Length=408, Percent_Identity=20.5882352941176, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51379; Mature: 51248

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNLVSEQLLAANGLKHQDLFVILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSY
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEHHHEECCCCC
NIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIARDSGDGKVQTLGAVEHSPLY
CCCCCCCEEEECCCCCCCEECCCEEEEEEHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
TSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSGVYELILVAATDGTLAADVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHH
PLVRLSVSVLIEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
HHHHEEEEEEEECCCCHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDG
HCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCC
TMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPM
EEEECCCCEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCC
PRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTK
CCCCCEEECCCCCCHHHHHHHHHCCEECCCCCCCEEEEECCEEEEECCCEEEEECCCCCC
PVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
CCCCCEEECCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C
>Mature Secondary Structure 
SLNLVSEQLLAANGLKHQDLFVILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSY
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEHHHEECCCCC
NIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIARDSGDGKVQTLGAVEHSPLY
CCCCCCCEEEECCCCCCCEECCCEEEEEEHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
TSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSGVYELILVAATDGTLAADVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHH
PLVRLSVSVLIEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
HHHHEEEEEEEECCCCHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDG
HCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCC
TMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPM
EEEECCCCEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCC
PRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTK
CCCCCEEECCCCCCHHHHHHHHHCCEECCCCCCCEEEEECCEEEEECCCEEEEECCCCCC
PVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
CCCCCEEECCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]