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The map label for this gene is xni [H]

Identifier: 209398738

GI number: 209398738

Start: 3757852

End: 3758607

Strand: Direct

Name: xni [H]

Synonym: ECH74115_4062

Alternate gene names: 209398738

Gene position: 3757852-3758607 (Clockwise)

Preceding gene: 209396781

Following gene: 209399079

Centisome position: 67.44

GC content: 52.91

Gene sequence:

>756_bases
GTGGCTGTTCATTTGCTTATTGTCGATGCACTGAATCTTATTCGTCGCATTCATGCCGTTCAGGGGTCGCCCTGTGTCGA
AACCTGCCAGCATGCGCTCGATCAGCTCATTATGCACAGCCAGCCAACCCACGCGGTCGCCGTTTTTGACGATGAAAACC
GCAGTAGCGGCTGGCGTCATCAGCGTTTACCAGATTACAAAGCGGGTCGACCGCCAATGCCGGAAGAGTTGCACGACGAG
ATGCCTGCATTACGCGCCGCCTTTGAGCAACGCGGCGTCCCGTGCTGGTCAACCAGCGGCAACGAAGCCGATGACTTAGC
CGCCACGCTGGCGGTCAAAGTGACACAGGCCGGGCATCAGGCAACGATTGTTTCGACAGATAAAGGCTACTGTCAGTTAC
TTTCACCGACATTACGTATTCGTGATTACTTCCAGAAACGTTGGCTGGATGCGCCATTTATCGATAAAGAATTTGGCGTT
CAACCGCAGCAGTTGCCCGATTACTGGGGACTTGCGGGGATCAGCAGTTCAAAGGTACCGGGTGTTGCGGGAATCGGACC
AAAAAGCGCCACGCAGCTGCTGGTCGAGTTTCAGAGTCTGGAAGGGATATATGAGAATCTGGATGCGGTTGCCGAAAAGT
GGCGCAAAAAATTAGAAACCCATAAAGAGATGGCGTTTCTGTGCCGCGATATTGCCCGCTTACAAACCGATTTGCATATC
GACGGCAATTTACAGCAATTGCGGTTGGTACGGTAA

Upstream 100 bases:

>100_bases
AGGCCTCGTTTTGCGAGGCCTCTTCCCGATTTCTCATCCAGCCATAGCCTGTTCCAGTATCGAATGTTACCCTTATCGCC
TGATCTTTAAGGGGGTTATC

Downstream 100 bases:

>100_bases
CGGCGTGCCGGATACGCCGCAAACGTCGCATCCGGCATTATCACATCAGCGCATTTACCAGGCGGTATGGTAAAGCTCTA
CAATATCCTCAAGCGTTGCT

Product: exonuclease IX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDE
MPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGV
QPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHI
DGNLQQLRLVR

Sequences:

>Translated_251_residues
MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDE
MPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGV
QPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHI
DGNLQQLRLVR
>Mature_250_residues
AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEM
PALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQ
PQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHID
GNLQQLRLVR

Specific function: May have a role in processing of nucleic acids. It is probably not an exonuclease; metal-binding residues found in paralogs are missing [H]

COG id: COG0258

COG function: function code L; 5'-3' exonuclease (including N-terminal domain of PolI)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain [H]

Homologues:

Organism=Escherichia coli, GI226510970, Length=251, Percent_Identity=100, Blast_Score=522, Evalue=1e-149,
Organism=Escherichia coli, GI1790294, Length=261, Percent_Identity=31.8007662835249, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR002421
- InterPro:   IPR020047
- InterPro:   IPR008918
- InterPro:   IPR022895 [H]

Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 28166; Mature: 28035

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRH
CEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCC
QRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCE
ATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVP
EEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHCCCHHCCCCCCCCCCC
GVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DGNLQQLRLVR
CCCHHHHEECC
>Mature Secondary Structure 
AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRH
EEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCC
QRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCE
ATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVP
EEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHCCCHHCCCCCCCCCCC
GVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DGNLQQLRLVR
CCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA