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The map label for this gene is lsrF [H]

Identifier: 209398692

GI number: 209398692

Start: 2044623

End: 2045498

Strand: Direct

Name: lsrF [H]

Synonym: ECH74115_2130

Alternate gene names: 209398692

Gene position: 2044623-2045498 (Clockwise)

Preceding gene: 209400955

Following gene: 209396806

Centisome position: 36.69

GC content: 49.89

Gene sequence:

>876_bases
ATGGCAGATTTAGACGATATTAAAGATGGTAAAGATTTTCGTACCGATCAACCGCAAAAAAATATCCCTTTTACCCTGAA
AGGTTGCGGTGCGCTGGATTGGGGAATGCAGTCACGCTTATCGCGGATATTTAATCCGAAAACGGGTAAAACCGTGATGC
TGGCTTTTGACCATGGTTATTTTCAGGGACCAACTACCGGACTTGAACGCATTGATATAAATATCGCCCCGCTGTTTGAA
CATGCCGATGTATTAATGTGTACGCGCGGGATTTTGCGCAGCGTAGTTCCCCCGGCGACCAATAAGCCGGTGGTACTGCG
GGCGTCAGGTGCGAACTCTATCCTGGCGGAATTAAGCAATGAAGCCGTGGCGTTATCGATGGATGACGCCGTGCGCCTGA
ACAGTTGCGCGGTGGCGGCGCAGGTTTATATCGGCAGCGAATATGAACATCAGTCGATCAAAAATATTATTCAGCTGGTC
GATGCCGGAATGAAAGTGGGAATGCCGACCATGGCCGTGACTGGCGTGGGCAAAGACATGGTGCGCGATCAGCGTTATTT
CTCGCTCGCGACTCGAATCGCCGCTGAAATGGGGACGCAAATTATCAAAACCTATTATGTCGAAAAAGGTTTTGAACGGA
TTGTTGCCGGATGTCCGGTACCCATTGTTATTGCTGGCGGTAAAAAATTACCGGAGCGCGAGGCGCTGGAAATGTGCTGG
CAGGCTATCGATCAGGGCGCTTCTGGTGTGGATATGGGGCGTAATATTTTCCAGTCTGACCATCCGGTGGCGATGATGAA
AGCCGTACAGGCGGTGGTTCACCATAACGAAACGGCTGATCGGGCATATGAACTCTATCTGAGTGAAAAACAGTAA

Upstream 100 bases:

>100_bases
ATGGTAATGGCATCGTACTGTTACCGGAGCGCGTGATATTCAACAAAGAGAATATCGGCAAATACGATTTCTGATGTGCA
TTACTTAACCGGAGTAAGTT

Downstream 100 bases:

>100_bases
CTGCGGATTTAAGGAGAAGAATTATGCACGTCACACTGGTTGAAATTAACGTTCATGAAGACAAGGTTGACGAGTTTATC
GAAGTTTTTCGCCAGAACCA

Product: aldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MADLDDIKDGKDFRTDQPQKNIPFTLKGCGALDWGMQSRLSRIFNPKTGKTVMLAFDHGYFQGPTTGLERIDINIAPLFE
HADVLMCTRGILRSVVPPATNKPVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLV
DAGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGTQIIKTYYVEKGFERIVAGCPVPIVIAGGKKLPEREALEMCW
QAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHNETADRAYELYLSEKQ

Sequences:

>Translated_291_residues
MADLDDIKDGKDFRTDQPQKNIPFTLKGCGALDWGMQSRLSRIFNPKTGKTVMLAFDHGYFQGPTTGLERIDINIAPLFE
HADVLMCTRGILRSVVPPATNKPVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLV
DAGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGTQIIKTYYVEKGFERIVAGCPVPIVIAGGKKLPEREALEMCW
QAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHNETADRAYELYLSEKQ
>Mature_290_residues
ADLDDIKDGKDFRTDQPQKNIPFTLKGCGALDWGMQSRLSRIFNPKTGKTVMLAFDHGYFQGPTTGLERIDINIAPLFEH
ADVLMCTRGILRSVVPPATNKPVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLVD
AGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGTQIIKTYYVEKGFERIVAGCPVPIVIAGGKKLPEREALEMCWQ
AIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHNETADRAYELYLSEKQ

Specific function: Could be involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle [H]

COG id: COG1830

COG function: function code G; DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787796, Length=291, Percent_Identity=99.3127147766323, Blast_Score=605, Evalue=1e-174,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002915 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 31895; Mature: 31764

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLDDIKDGKDFRTDQPQKNIPFTLKGCGALDWGMQSRLSRIFNPKTGKTVMLAFDHGY
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCC
FQGPTTGLERIDINIAPLFEHADVLMCTRGILRSVVPPATNKPVVLRASGANSILAELSN
CCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHCC
EAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLVDAGMKVGMPTMAVTGVGKDM
CEEEEECCCCHHHHHHHEEEHEEECCCCCHHHHHHHHHHHHHHHHCCCCHHEEECCCHHH
VRDQRYFSLATRIAAEMGTQIIKTYYVEKGFERIVAGCPVPIVIAGGKKLPEREALEMCW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHH
QAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHNETADRAYELYLSEKQ
HHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHEEEEEECCC
>Mature Secondary Structure 
ADLDDIKDGKDFRTDQPQKNIPFTLKGCGALDWGMQSRLSRIFNPKTGKTVMLAFDHGY
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCC
FQGPTTGLERIDINIAPLFEHADVLMCTRGILRSVVPPATNKPVVLRASGANSILAELSN
CCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHCC
EAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLVDAGMKVGMPTMAVTGVGKDM
CEEEEECCCCHHHHHHHEEEHEEECCCCCHHHHHHHHHHHHHHHHCCCCHHEEECCCHHH
VRDQRYFSLATRIAAEMGTQIIKTYYVEKGFERIVAGCPVPIVIAGGKKLPEREALEMCW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHH
QAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHNETADRAYELYLSEKQ
HHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA