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The map label for this gene is exoX [H]

Identifier: 209398184

GI number: 209398184

Start: 2434245

End: 2434907

Strand: Direct

Name: exoX [H]

Synonym: ECH74115_2580

Alternate gene names: 209398184

Gene position: 2434245-2434907 (Clockwise)

Preceding gene: 209399166

Following gene: 209400324

Centisome position: 43.69

GC content: 52.04

Gene sequence:

>663_bases
ATGTTGCGCATTATCGATACAGAAACCTGCGGTTTGCAGGGAGGGATCGTTGAGATTGCCTCTGTTGATGTCATTGACGG
GAAAATCGTCAACCCCATGAGCCACCTGGTGCACCCCGATCGTCCTATTAGTCCACAAGCGATGGCGATTCATCGCATCA
CCGAAGCCATGGTCGCCGATAAACCGTGGATTGAAGATGTGATCCCACACTATTACGGTAGTGAATGGTATGTCGCGCAT
AACGCCAGCTTTGACCGCCGCGTACTGCCTGAGATGCCCGGTGAGTGGATTTGCACTATGAAACTGGCCCGTCGTTTGTG
GCCAGGGATCAAGTACAGCAATATGGCGTTATATAAAACACGGAAGCTCAATGTACAGACGCCGCCGGGCCTGCATCATC
ACCGCGCGTTGTATGACTGTTATATCACCGCCGCGTTGCTTATCGATATTATGAACACCTCCGGCTGGACGGCAGAACAG
ATGGCCGATATGACCGGACGTCCGTCGTTGATGACGACCTTCACCTTTGGCAAATACCGTGGCAAAGCGGTTTCCGACGT
TGCCGAACGCGATCCGGGCTATCTGCGCTGGTTGTTTAATAACCTGGACAGCATGAGCCCGGAGCTGCGTTTAACACTGA
AACATTATCTGGAAAATACCTAA

Upstream 100 bases:

>100_bases
CCGATCGTGGTTCATTATTGTTAGTCGGTCAGCGTTCATCACAGGGTTGGCAAGGCGATATCATTCCATTACGCTAGGCT
TTTTCGGCCTGGAGCATGCC

Downstream 100 bases:

>100_bases
TCCGCAGGCCTAGCGGGTAATGTTCCCTGCGCCAGCGCGACCAGAAAAGCATATTCCATCGCTACGCCTTCGTACGATTT
AAAGCGACCAGATTTACCGC

Product: exodeoxyribonuclease X

Products: NA

Alternate protein names: Exodeoxyribonuclease X; Exo X; Exonuclease X [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVHPDRPISPQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAH
NASFDRRVLPEMPGEWICTMKLARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
MADMTGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLENT

Sequences:

>Translated_220_residues
MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVHPDRPISPQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAH
NASFDRRVLPEMPGEWICTMKLARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
MADMTGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLENT
>Mature_220_residues
MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVHPDRPISPQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAH
NASFDRRVLPEMPGEWICTMKLARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
MADMTGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLENT

Specific function: Capable of degrading both single-strand and double- strand DNA with 3' to 5' polarity. Has higher affinity for ssDNA ends than for dsDNA. May facilitate recombinational repair by pre- synaptic and/or post-synaptic DNA degradation [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788149, Length=220, Percent_Identity=99.0909090909091, Blast_Score=457, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 25132; Mature: 25132

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVHPDRPISPQAMAIHRITEAMVAD
CEEEEECCCCCCCCCEEEEEEEEEECCCEECHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
KPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKLARRLWPGIKYSNMALYKT
CCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCEEEEEE
RKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQMADMTGRPSLMTTFTFGKYR
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEECCCCC
GKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLENT
CCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVHPDRPISPQAMAIHRITEAMVAD
CEEEEECCCCCCCCCEEEEEEEEEECCCEECHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
KPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKLARRLWPGIKYSNMALYKT
CCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCEEEEEE
RKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQMADMTGRPSLMTTFTFGKYR
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEECCCCC
GKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLENT
CCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]