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The map label for this gene is xerC [H]

Identifier: 209397621

GI number: 209397621

Start: 4893060

End: 4893956

Strand: Direct

Name: xerC [H]

Synonym: ECH74115_5250

Alternate gene names: 209397621

Gene position: 4893060-4893956 (Clockwise)

Preceding gene: 209398950

Following gene: 209399544

Centisome position: 87.81

GC content: 54.07

Gene sequence:

>897_bases
ATGACCGATTTACACACCGATGTAGAACGCTACCTACGTTATCTGAGCGTGGAGCGGCAGCTTAGTCCGATAACTCTGCT
TAACTACCAGCGACAGCTTGAGGCGATCATCAATTTTGCCAGCGAAAACGGCCTGCAAAACTGGCAGCAATGCGATGCAG
CGATGGTGCGCAATTTTGCTGTACGCAGTCGCCGTAAAGGGCTGGGCGCGGCAAGCCTCGCATTACGCCTCTCTGCGCTA
CGTAGCTTTTTTGACTGGCTGGTCAGCCAGAACGAACTCAAAGCTAACCCGGCGAAAGGTGTTTCGGCACCGAAAACGCC
ACGTCATCTGCCGAAAAATATCGACGTCGATGATATAAATCGCCTGTTGGATATTGATATCAACGATCCCCTCGCTGTGC
GCGACCGTGCAATGCTGGAAGTGATGTACGGCGCGGGCCTGCGTCTTTCCGAGCTGGTGGGGCTGGACATCAAACACCTC
GACCTGGAGTCCGGCGAAGTGTGGGTGATGGGGAAAGGCAGCAAAGAGCGCCGCCTGCCGATTGGTCGTAACGCTTTGTC
ATGGATTGAGCACTGGCTTGATTTGCGCGACCTGTTTGGTAGCGAAGACGACGCGCTTTTTCTGTCGAAACTGGGCAAGC
GTATCTCCGCGCGTAATGTGCAGAAACGCTTTGCCGAATGGGGCATAAAACAAGGGCTGAATAATCACGTTCACCCGCAT
AAATTACGTCACTCGTTCGCTACGCATATGCTGGAGTCGAGCGGCGATCTTCGTGGTGTGCAGGAGCTGCTGGGTCATGC
CAACCTCTCCACCACGCAAATCTATACTCATCTTGATTTTCAACACCTTGCCTCGGTGTACGATGCGGCGCATCCACGCG
CCAAACGGGGGAAATAA

Upstream 100 bases:

>100_bases
GCCGCGATGCCAGTCACTATCAACAAGGGCAGGGAACGCAGTTACTTCATGAAATTGCGCTGATGTTGCCGGAGCTTCTG
GAGCGTTGGATTGAACGCGT

Downstream 100 bases:

>100_bases
TGCGTTTTTACCGGCCTTTGGGGCGCATCTCGGCGCTCACCTTTGACCTGGATGATACCCTTTACGATAACCGTCCGGTG
ATTTTGCGCACCGAGCAGGA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQNWQQCDAAMVRNFAVRSRRKGLGAASLALRLSAL
RSFFDWLVSQNELKANPAKGVSAPKTPRHLPKNIDVDDINRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHL
DLESGEVWVMGKGSKERRLPIGRNALSWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPH
KLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK

Sequences:

>Translated_298_residues
MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQNWQQCDAAMVRNFAVRSRRKGLGAASLALRLSAL
RSFFDWLVSQNELKANPAKGVSAPKTPRHLPKNIDVDDINRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHL
DLESGEVWVMGKGSKERRLPIGRNALSWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPH
KLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
>Mature_297_residues
TDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQNWQQCDAAMVRNFAVRSRRKGLGAASLALRLSALR
SFFDWLVSQNELKANPAKGVSAPKTPRHLPKNIDVDDINRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLD
LESGEVWVMGKGSKERRLPIGRNALSWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPHK
LRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerD binding sites by a short central region, forming

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=298, Percent_Identity=97.6510067114094, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=37.3287671232877, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1790768, Length=167, Percent_Identity=29.3413173652695, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790767, Length=182, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33879; Mature: 33748

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQNWQQCDAAMVRNFA
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKTPRHLPKNIDVDDIN
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLP
HEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHEEECCCCCEEEEECCCCCCCCC
IGRNALSWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPH
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
KLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQNWQQCDAAMVRNFA
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKTPRHLPKNIDVDDIN
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLP
HEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHEEECCCCCEEEEECCCCCCCCC
IGRNALSWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPH
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
KLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA