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The map label for this gene is yhfK

Identifier: 209397460

GI number: 209397460

Start: 4309789

End: 4311879

Strand: Direct

Name: yhfK

Synonym: ECH74115_4668

Alternate gene names: 209397460

Gene position: 4309789-4311879 (Clockwise)

Preceding gene: 209398039

Following gene: 209396309

Centisome position: 77.35

GC content: 52.8

Gene sequence:

>2091_bases
ATGTGGCGCAGACTGATTTATCACCCCGATATTAACTATGCACTGCGACAAACGCTGGTGCTATGTTTGCCCGTGGCCGT
TGGGTTAATGCTTGGCGAATTACGATTCGGTCTGCTCTTCTCTCTCGTTCCTGCCTGTTGCAATATTGCGGGCCTTGATA
CGCCTCATAAACGTTTTTTCAAACGCTTAATCATTGGTGCGTCGCTGTTTGCCACCTGTAGCTTACTGACACAGCTGCTA
CTGGCAAAAGATGTTCCCCTGCCTTTTTTGCTGACCGGATTAACGCTGGTACTTGGCGTCACTGCTGAGTTGGGGCCATT
GCACGCAAAATTGCTTCCCGCATCGCTGCTGGCAGCCATTTTTACCCTCAGTCTGGCGGGATACATGCCGGTCTGGGAAC
CGTTGCTCATCTATGCGTTGGGCACTCTCTGGTACGGATTGTTTAACTGGTTTTGGTTCTGGATCTGGCGCGAACAACCG
CTGCGCGAGTCACTAAGTCTGCTGTACCGTGAACTGGCAGATTATTGTGAAGCCAAATACAGCCTGCTTACCCAGCACAC
CGACCCTGAAAAAGCGCTGCCGCCGCTGCTGGTGCGCCAGCAAAAAGCGGTCGATCTAATTACCCAGTGCTATCAGCAAA
TGCATATGCTTTCCGCGCAAAATAATACTGACTACAAGCGGATGCTGCGTATTTTCCAGGAGGCGCTGGATTTACAGGAA
CATATTTCGGTCAGTTTGCATCAGCCGGAAGAGGTGCAAAAGCTGGTCGAGCGTAGCCATGCGGAAGAAGTTATCCGCTG
GAATGCGCAAACCGTCGCCGCTCGCCTGCGCGTGCTGGCTGATGACATTCTTTACCATCGCCTGCCGACGCGTTTTACGA
TGGAAAAGCAAATTGGCGCACTGGAAAAAATCGCCCGCCAGCATCCGGATAATCCGGTTGGGCAATTCTGCTATTGGCAC
TTCAGCCGCATCGCCCGCGTGCTGCGCACCCAAAAACCGCTCTATGCCCGTGACTTACTGGCCGATAAACAGCGGCGAAT
GCCGTTACTTCCGGCGCTGAAAAGTTATTTGTCACTAAAGTCTCCGGCGCTACGCAATGCCGGACGACTCAGTGTGATGT
TAAGCGTTGCCAGCTTGATGGGCACCGCGCTGCATCTGCCGAAGTCGTACTGGATCCTGATGACGGTATTGCTGGTGACG
CAAAATGGCTATGGCGCAACCCGTCTGAGGATTGTGAATCGCTCCGTGGGAACCGTGGTCGGGTTAATCATTGCGGGCGT
GGCGCTGCACTTTAAAATTCCCGAAGGTTACACCCTGACCTTGATGCTGATTACCACCCTTGCCAGCTACCTGATATTGC
GCAAAAACTACGGCTGGGCGACGGTCGGTTTTACTATTACCGCAGTGTATACCCTGCAACTGTTGTGGCTGAACGGTGAG
CAGTACATCCTTCCGCGTCTTATCGATACCATTATTGGTTGTTTAATTGCTTTCGGTGGTACCGTCTGGCTGTGGCCGCA
GTGGCAGAGCGGGTTATTGCGTAAAAACGCCCATGACGCTTTAGAAGCCTATCAGGAAGCGATTCGCTTGATTCTGAGCG
AGGATCCGCAACCAACGCCACTGGCCTGGCAGCGAATGCGGGTAAATCAGGCGCATAACACTCTGTATAACTCATTGAAT
CAGGCGATGCAGGAACCAGCGTTCAACAGCCATTATCTGGCAGATATGAAACTGTGGGTAACGCACAGTCAGTTTATTGT
TGAACATATTAATGCCATGACCACGCTGGCGCGGGAACACCGGGCATTGCCACCTGAACTGGCACAAGAGTATTTACAGT
CTTGTGAAATCGCCATTCAGCGTTGTCAGCAGCGACTGGAGTATGACGAACCGGGTAGTTCTGGCGATGCCAATATCATG
GATGCGCCGGAGATGCAGCCGCACGAAGGCGCGGCAGGTACGCTGGAGCAGCATTTACAGCGGGTTATTGGTCATCTGAA
CACCATGCACACCATTTCGTCGATGGCATGGCGTCAGCGACCGCATCACGGGATTTGGCTGAGTCGCAAGTTGCGGGATT
CGAAGGCGTAA

Upstream 100 bases:

>100_bases
ACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAATCCCGTCGGAGTGGCGCGTTACCTGGTAGC
GCGCCATTTTGTTTCCCCCG

Downstream 100 bases:

>100_bases
TGCAGGCTAAACCATCGGATAAGGCATGCACGCCGCATCCGACATCTTTTGCCTGATGCGTCTTATTTACGCCCCAACCA
CCTTCGCCACCGCGTGGGCG

Product: integral membrane protein, YccS/YhfK family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVPACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQLL
LAKDVPLPFLLTGLTLVLGVTAELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQP
LRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLSAQNNTDYKRMLRIFQEALDLQE
HISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARLRVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWH
FSRIARVLRTQKPLYARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWILMTVLLVT
QNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASYLILRKNYGWATVGFTITAVYTLQLLWLNGE
QYILPRLIDTIIGCLIAFGGTVWLWPQWQSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLN
QAMQEPAFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQRLEYDEPGSSGDANIM
DAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPHHGIWLSRKLRDSKA

Sequences:

>Translated_696_residues
MWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVPACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQLL
LAKDVPLPFLLTGLTLVLGVTAELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQP
LRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLSAQNNTDYKRMLRIFQEALDLQE
HISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARLRVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWH
FSRIARVLRTQKPLYARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWILMTVLLVT
QNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASYLILRKNYGWATVGFTITAVYTLQLLWLNGE
QYILPRLIDTIIGCLIAFGGTVWLWPQWQSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLN
QAMQEPAFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQRLEYDEPGSSGDANIM
DAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPHHGIWLSRKLRDSKA
>Mature_696_residues
MWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVPACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQLL
LAKDVPLPFLLTGLTLVLGVTAELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQP
LRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLSAQNNTDYKRMLRIFQEALDLQE
HISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARLRVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWH
FSRIARVLRTQKPLYARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWILMTVLLVT
QNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASYLILRKNYGWATVGFTITAVYTLQLLWLNGE
QYILPRLIDTIIGCLIAFGGTVWLWPQWQSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLN
QAMQEPAFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQRLEYDEPGSSGDANIM
DAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPHHGIWLSRKLRDSKA

Specific function: Unknown

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the yccS/yhfK family

Homologues:

Organism=Escherichia coli, GI87082248, Length=696, Percent_Identity=100, Blast_Score=1427, Evalue=0.0,
Organism=Escherichia coli, GI87081808, Length=205, Percent_Identity=33.6585365853659, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHFK_ECOLI (P45537)

Other databases:

- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_004431.1
- RefSeq:   NP_417817.2
- ProteinModelPortal:   P45537
- STRING:   P45537
- EnsemblBacteria:   EBESCT00000002449
- EnsemblBacteria:   EBESCT00000017808
- GeneID:   947866
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5701
- KEGG:   eco:b3358
- EchoBASE:   EB2743
- EcoGene:   EG12906
- eggNOG:   COG1289
- GeneTree:   EBGT00050000009269
- HOGENOM:   HBG417113
- OMA:   DANIMDS
- ProtClustDB:   CLSK880639
- BioCyc:   EcoCyc:G7721-MONOMER
- Genevestigator:   P45537
- InterPro:   IPR006726
- InterPro:   IPR010020
- TIGRFAMs:   TIGR01667

Pfam domain/function: PF04632 FUSC

EC number: NA

Molecular weight: Translated: 79500; Mature: 79500

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1208024c)-; HASH(0xed50600)-; HASH(0x113d79fc)-; HASH(0x12202524)-; HASH(0x119dcd68)-; HASH(0x11f3645c)-; HASH(0x12039380)-; HASH(0x11f3239c)-; HASH(0x12249380)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503