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The map label for this gene is yeiQ [H]

Identifier: 209396686

GI number: 209396686

Start: 3042536

End: 3044002

Strand: Direct

Name: yeiQ [H]

Synonym: ECH74115_3310

Alternate gene names: 209396686

Gene position: 3042536-3044002 (Clockwise)

Preceding gene: 209400095

Following gene: 209395981

Centisome position: 54.6

GC content: 52.69

Gene sequence:

>1467_bases
ATGAATACAATCGCCTCCGTTACGCTCCCGCATCATGTACACGCTCCACGCTACGATCGCCAGCAGTTGCAATCACGTAT
CGTTCATTTTGGCTTTGGAGCCTTTCACCGCGCACATCAGGCGTTACTGACCGATCGTGTGCTGAATGCCCAGGGCGGCG
ACTGGGGGATCTGTGAAATCAGCTTGTTCAGCGGTGATCAACTGATGAGCCAGCTCCGCGCACAGAACCATTTATATACC
GTGCTGGAGAAAGGGGCGGACGGCAATCAGGCGATAATTGTCGGTGCCGTTCACGAATGCCTGAATGCAAAACTGGATTC
CTTAGCGGCAATTATTGAGAAATTTTGCGAGCCACAGGTGGCAATTGTTTCCCTGACGATTACCGAAAAAGGCTATTGTA
TTGACCCGGCCACCGGTGCACTCGACACCAGCAATCCGCGGATTATTCACGATCTACAAACCCCTGAAGAACCTCACTCC
GCACCGGGTATTCTCGTCGAAGCACTGAAACGCCGCCGTGAGCGCGGCCTTACACCGTTTACCGTGCTCTCCTGCGACAA
TATTCCCGACAATGGCCATGTGGTGAAAAACGCGGTGCTGGGAATGGCAGAAAAACGTTCGCCAGAACTCGCCGGGTGGA
TAAAAGAACACGTCAGTTTTCCGGGAACCATGGTCGACCGCATTGTTCCGGCTGCAACCGACGAATCACTGGCAGAAATC
AGCCAGCATCTGGGGGTAAATGATCCCTGCGCGATTAGCTGCGAACCGTTTATCCAGTGGGTGGTGGAAGATAACTTCGT
CGCTGGGCGTCCTGCCTGGGAAGTCGCAGGTGTACAAATGGTGAATGATGTCCTGCCATGGGAAGAGATGAAACTGCGGA
TGCTTAATGGCAGCCACTCTTTTCTCGCTTATCTGGGTTACCTCTCAGGATTCGCCCATATCAGTGATTGCATGCAGGAT
CGCGCATTTCGCCATGCCGCCAGAACATTAATGCTGGATGAGCAAGCGCCGACACTGCGGATTAAAGATGTCGATTTAAC
ACAATATGCGGATAAGTTAATTGCACGTTTTGCTAATCCGGCGCTGAAACATAAGACCTGGCAAATCGCGATGGATGGCA
GCCAGAAATTACCGCAACGCATGCTGGCAGGTATTCGCATACATCTGGGGCGCGAAACGGACTGGTCGTTGCTGGCATTA
GGCGTTGCAGGCTGGATGCGTTACGTCAGCGGCGTTGATGATGCCGGAAATGCCATTGATGTTCGCGATCCGCTTAGCGA
TAAAATTCGCGATCTTGTTGCGGGCAGCATCAGTGAGCAACGCGTCACCGCCCTGCTTTCCCTGCGTGAAGTTTTCGGTG
ATGATCTGCCAGATAACCCGCATTTTGTGCAGGCCATCGAACAAGCCCGGCAACAAATCGCACAATTCGGCGCGCATCAG
GCGCTATTAAACACCCTCAAAATTTAA

Upstream 100 bases:

>100_bases
CCTCACACTTCATCGCATTAACAATCCAGACCAATTTCAATTGCTGTCATATAACTTTACACTGTCATTGTTAATTAATC
GTTACTAAGACATGACTCCT

Downstream 100 bases:

>100_bases
CGATTTCTGCGGTTAAAGCGGATGAAGCTCGCCTTCGTCCGCTCTCCCCTTCTCTTTTCTGCCGTTTTTAGCCAGGATTA
ACGCTCAGTTAACTTACCAG

Product: mannitol dehydrogenase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQAIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
APGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQD
RAFRHAARTLMLDEQAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKIRDLVAGSISEQRVTALLSLREVFGDDLPDNPHFVQAIEQARQQIAQFGAHQ
ALLNTLKI

Sequences:

>Translated_488_residues
MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQAIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
APGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQD
RAFRHAARTLMLDEQAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKIRDLVAGSISEQRVTALLSLREVFGDDLPDNPHFVQAIEQARQQIAQFGAHQ
ALLNTLKI
>Mature_488_residues
MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQAIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
APGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQD
RAFRHAARTLMLDEQAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKIRDLVAGSISEQRVTALLSLREVFGDDLPDNPHFVQAIEQARQQIAQFGAHQ
ALLNTLKI

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family. UxuB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788497, Length=488, Percent_Identity=98.3606557377049, Blast_Score=992, Evalue=0.0,
Organism=Escherichia coli, GI1790779, Length=485, Percent_Identity=56.2886597938144, Blast_Score=554, Evalue=1e-159,
Organism=Escherichia coli, GI1787823, Length=464, Percent_Identity=55.1724137931034, Blast_Score=547, Evalue=1e-157,
Organism=Escherichia coli, GI1790028, Length=232, Percent_Identity=28.8793103448276, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI48994885, Length=482, Percent_Identity=22.8215767634855, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6324401, Length=476, Percent_Identity=39.7058823529412, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320765, Length=476, Percent_Identity=39.7058823529412, Blast_Score=363, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR023027
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 53943; Mature: 53943

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEI
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
SLFSGDQLMSQLRAQNHLYTVLEKGADGNQAIIVGAVHECLNAKLDSLAAIIEKFCEPQV
EECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCE
AIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHSAPGILVEALKRRRERGLTPF
EEEEEEEECCCEEECCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
TVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
EEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHH
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHS
HHHCCCCCCCEECHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHH
FLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDEQAPTLRIKDVDLTQYADKLIARFANP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHHCCH
ALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLALGVAGWMRYVSGVDDAGNAID
HHHCCEEEEEECCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
VRDPLSDKIRDLVAGSISEQRVTALLSLREVFGDDLPDNPHFVQAIEQARQQIAQFGAHQ
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALLNTLKI
HHHHHHCC
>Mature Secondary Structure
MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEI
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
SLFSGDQLMSQLRAQNHLYTVLEKGADGNQAIIVGAVHECLNAKLDSLAAIIEKFCEPQV
EECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCE
AIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHSAPGILVEALKRRRERGLTPF
EEEEEEEECCCEEECCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
TVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
EEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHH
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHS
HHHCCCCCCCEECHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHH
FLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDEQAPTLRIKDVDLTQYADKLIARFANP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHHCCH
ALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLALGVAGWMRYVSGVDDAGNAID
HHHCCEEEEEECCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
VRDPLSDKIRDLVAGSISEQRVTALLSLREVFGDDLPDNPHFVQAIEQARQQIAQFGAHQ
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALLNTLKI
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]