Click here to switch to the map view.

The map label for this gene is envY [H]

Identifier: 209396048

GI number: 209396048

Start: 660580

End: 661341

Strand: Reverse

Name: envY [H]

Synonym: ECH74115_0639

Alternate gene names: 209396048

Gene position: 661341-660580 (Counterclockwise)

Preceding gene: 209399136

Following gene: 209400942

Centisome position: 11.87

GC content: 46.19

Gene sequence:

>762_bases
ATGCAATTGAGCAGCAGTGAACCTTGCGTGGTGATCCTGACCGAAAAAGAGGTAGAGGTAAGCGTCAATAACCATGCTAC
GTTTACCCTTCCGAAAAACTACCTGGCCGCCTTCGCGTGCAACAATAACGTCATTGAACTCTCAACGTTAAATCACGTAT
TAATCACCCACATCAACCGTAACATCATCAACGATTATCTGTTGTTTTTAAATAAGAACTTAACCTGTGTAAAGCCCTGG
TCGCGGCTGGCTACCCCGGTTATCGCTTGTCATAGCCGTACACCGGAAGTGTTCCGGCTAGCCGCCAACCACAGCAAGCA
GCAACCCAGCAAACCCTGCGAAGCGGAGTTGACGCGCGCATTGCTTTTTACCGTATTGTCTAACTTTCTTGAGCAATCGC
GGTTTATTGCCCTACTGATGTATATCTTACGCAGCAGCGTCCGCGACAGCGTCTGCCGCATTATTCAAAGCGATATTCAG
CATTACTGGAATCTGCGAATTGTCGCCAGTTCGCTATGTTTAAGCCCCAGCCTGCTCAAAAAGAAATTAAAAAACGAAAA
TACCAGCTATAGCCAGATTGTCACAGAGTGTCGTATGCGTTACGCCGTACAGATGTTATTGATGGATAACAAAAATATCA
CTCAGGTGGCGCAATTATGTGGCTATAGCAGCACGTCGTACTTTATCTCTGTTTTTAAGGCGTTTTACGGCCTGACACCG
TTGAATTATCTCGCCAAACAGCGACAAAAAGTGATGTGGTGA

Upstream 100 bases:

>100_bases
CGTGCTAAAGAAAGAAGATCGTTATCGGCGAACGGGCCGATCACTCATGCAGGAAGCATAGATCCTTTGAGCGGAGTTTC
TGATATCTGAGGAGTGCGAA

Downstream 100 bases:

>100_bases
AGGGCAAAGCGGAAACGGATAAGACGGGCATAAATAAAGAAGAAATGGCGCGCCCTGCAGGATTCGAACCTGCGGCCCAC
GACTTAGAAGGTCGTTGCTC

Product: transcriptional regulator, AraC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNVIELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPW
SRLATPVIACHSRTPEVFRLAANHSKQQPSKPCEAELTRALLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQLCGYSSTSYFISVFKAFYGLTP
LNYLAKQRQKVMW

Sequences:

>Translated_253_residues
MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNVIELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPW
SRLATPVIACHSRTPEVFRLAANHSKQQPSKPCEAELTRALLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQLCGYSSTSYFISVFKAFYGLTP
LNYLAKQRQKVMW
>Mature_253_residues
MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNVIELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPW
SRLATPVIACHSRTPEVFRLAANHSKQQPSKPCEAELTRALLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQLCGYSSTSYFISVFKAFYGLTP
LNYLAKQRQKVMW

Specific function: Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins ompF and ompC and the lambda receptor, lamB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786778, Length=253, Percent_Identity=99.604743083004, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1790557, Length=252, Percent_Identity=56.7460317460317, Blast_Score=303, Evalue=7e-84,
Organism=Escherichia coli, GI1789933, Length=194, Percent_Identity=39.1752577319588, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1786776, Length=96, Percent_Identity=43.75, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789932, Length=127, Percent_Identity=40.1574803149606, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787776, Length=124, Percent_Identity=38.7096774193548, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 28991; Mature: 28991

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNVIELSTLNHVLITHINR
CCCCCCCCEEEEEECCCEEEEECCCEEEEECHHHHEEEEECCCEEEEEHHHHHHHHHHHH
NIINDYLLFLNKNLTCVKPWSRLATPVIACHSRTPEVFRLAANHSKQQPSKPCEAELTRA
HHHHHHHHHHCCCCEEECCHHHHCCHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHH
LLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQHYWNLRIVASSLCLSPSLLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQLCGYSSTSYFISVFKAFYGLTP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCH
LNYLAKQRQKVMW
HHHHHHHHHHCCC
>Mature Secondary Structure
MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNVIELSTLNHVLITHINR
CCCCCCCCEEEEEECCCEEEEECCCEEEEECHHHHEEEEECCCEEEEEHHHHHHHHHHHH
NIINDYLLFLNKNLTCVKPWSRLATPVIACHSRTPEVFRLAANHSKQQPSKPCEAELTRA
HHHHHHHHHHCCCCEEECCHHHHCCHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHH
LLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQHYWNLRIVASSLCLSPSLLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQLCGYSSTSYFISVFKAFYGLTP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCH
LNYLAKQRQKVMW
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2536924; 8905232; 9278503 [H]