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The map label for this gene is malZ [H]

Identifier: 209395918

GI number: 209395918

Start: 488084

End: 489898

Strand: Direct

Name: malZ [H]

Synonym: ECH74115_0480

Alternate gene names: 209395918

Gene position: 488084-489898 (Clockwise)

Preceding gene: 209396652

Following gene: 209400742

Centisome position: 8.76

GC content: 54.71

Gene sequence:

>1815_bases
ATGTTAAATGCATGGCACCTGCCGGTGCCCCCATTTGTTAAACAAAGCAAAGATCAACTGCTCATTACACTGTGGCTGAC
GGGCGAAGACCCACCGCAGCGCATTATGCTGCGTACAGAACACGATAACGAAGAAATGTCAGTACCAATGCATAAGCAGC
GCAGTCAGCCGCAGCCAGGCGTCACCGCATGGCGTGCGGCGATTGATCTCTCCAGCGGACAACCCCGGCGGCGTTACAGT
TTCAAACTGCTGTGGCACGATCGCCAGCGTTGGTTTACACCGCAGGGCTTCAGCCGAATGCCGCCGGCACGACTGGAGCA
GTTTGCCGTCGATGTACCGGATATCGGCCCACAATGGGCTGCGGATCAGATTTTTTATCAGATCTTCCCTGATCGTTTTG
CGCGTAGTCTTCCTCGTGAAGCTGAACAGGATCATGTCTATTACCATCATGCAGCCGGACAAGAGATCATCTTGCGTGAC
TGGGATGAACCGGTCACGGCGCAGGCGGGCGGATCAACGTTCTATGGCGGCGATCTGGACGGGATAAGCGAAAAACTGCC
GTATCTGAAAAAGCTTGGCGTGACGGCGCTGTATCTCAATCCGGTGTTTAAAGCTCCCAGCGTACATAAATACGATACCG
AGGATTATCGCCATGTCGATCCGCAGTTTGGCGGTGATGGGGCGTTGCTGCGCTTACGCCACAATACGCAGCAGCTGGGA
ATGCGGCTGGTGCTGGATGGCGTGTTTAACCACAGTGGCGATTCCCATGCCTGGTTTGACAGGCACAATCGTGGCACGGG
GGGAGCTTGTCACAACCCCGAATCGCCCTGGCGCGACTGGTACTCGTTTAGTGATGATGGCACGGCGCTCGACTGGCTTG
GCTATGCCAGCTTGCCGAAGCTGGATTATCAGTCGGAAAGTCTGGTGAATGAAATTTATCGCGGGGAAGACAGTATTGTC
CGCCACTGGCTGAAAGCGCCGTGGAATATGGACGGCTGGCGGCTGGATGTGGTGCATATGCTGGGGGAAGCGGGTGGGGC
GCGCAATAATTTGCAGCACGTTGCTGGGATCACCGAAGCGGCGAAAGAAACCCAGCCGGAAGCGTATATAGTTGGAGAGC
ATTTTGGCGATGCACGGCAATGGTTACAGGCCGATGTGGAAGATGCCGCCATGAACTATCGCGGCTTCACATTCCCGTTG
TGGGGATTTCTTGCCAATACCGACATCTCTTACGATCCGCAGCAAATTGACGCTCAAACCTGTATGGCCTGGATGGATAA
TTACCGCGCAGGGCTTTCTCATCAACAGCAATTACGTATGTTTAATCAGCTCGACAGCCACGATACTGCGCGATTTAAAA
CGCTGCTCGGTCGGGAGGTTGCGCGCCTGCCCCTGGCAGTGGTCTGGCTGTTCACCTGGCCTGGTGTACCGTGCATTTAT
TACGGTGATGAAGTGGGACTGGATGGCAAAAATGATCCGTTTTGCCGTAAGCCGTTCCCCTGGCAGGTGGAAAAACAGGA
TATGGCGTTATTCGCGTTGTACCAGCGAATGATTGCGCTGCGTAAGAAAAGTCAGGCGCTGCGTCGTGGCGGCTGTCAGG
TGCTGTATGCGGAAGATAACGTGGTGGTATTTGTCCGCGTGCTGAATCAGCAGCGTGTACTGGTGGCAATTAACCGTGGC
GAAGCCTGTGAAGTGGTGCTACCCGCGTCACCGTTTCTTAATGTCGTGCAATGGCAACGCAAAGAAGGCCATGGGCAACT
GACAGACGGGATTCTGGCTTTGCCTGCCATTTCGGCTACGGTGTGGATGAACTAA

Upstream 100 bases:

>100_bases
ATCCGCCCCCGTCCTCCTCCCCCAAATATCCTTCAGATGATGAGTGATCCTGCATTAGGCTATGGCAAGGTGATCAGATT
TTCATCACAGGGGAATTATG

Downstream 100 bases:

>100_bases
AGCATCTGTTTTATTTGTTACGTCGTTAGTCACCAGCCCTGACACTACGCAGCGCAAAAAAGCTGCTCAATGTCAGGGCT
GAATTTGTTAAATATTTGTC

Product: maltodextrin glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase [H]

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEEMSVPMHKQRSQPQPGVTAWRAAIDLSSGQPRRRYS
FKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILRD
WDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHNTQQLG
MRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIV
RHWLKAPWNMDGWRLDVVHMLGEAGGARNNLQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFPL
WGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGREVARLPLAVVWLFTWPGVPCIY
YGDEVGLDGKNDPFCRKPFPWQVEKQDMALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINRG
EACEVVLPASPFLNVVQWQRKEGHGQLTDGILALPAISATVWMN

Sequences:

>Translated_604_residues
MLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEEMSVPMHKQRSQPQPGVTAWRAAIDLSSGQPRRRYS
FKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILRD
WDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHNTQQLG
MRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIV
RHWLKAPWNMDGWRLDVVHMLGEAGGARNNLQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFPL
WGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGREVARLPLAVVWLFTWPGVPCIY
YGDEVGLDGKNDPFCRKPFPWQVEKQDMALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINRG
EACEVVLPASPFLNVVQWQRKEGHGQLTDGILALPAISATVWMN
>Mature_604_residues
MLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEEMSVPMHKQRSQPQPGVTAWRAAIDLSSGQPRRRYS
FKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILRD
WDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHNTQQLG
MRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIV
RHWLKAPWNMDGWRLDVVHMLGEAGGARNNLQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFPL
WGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGREVARLPLAVVWLFTWPGVPCIY
YGDEVGLDGKNDPFCRKPFPWQVEKQDMALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINRG
EACEVVLPASPFLNVVQWQRKEGHGQLTDGILALPAISATVWMN

Specific function: May play a role in regulating the intracellular level of maltotriose. Cleaves glucose from the reducing end of maltotriose and longer maltodextrins with a chain length of up to 7 glucose units [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Escherichia coli, GI1786604, Length=604, Percent_Identity=98.841059602649, Blast_Score=1242, Evalue=0.0,
Organism=Escherichia coli, GI1790687, Length=188, Percent_Identity=31.3829787234043, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789995, Length=143, Percent_Identity=30.0699300699301, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32565753, Length=351, Percent_Identity=25.3561253561254, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322245, Length=194, Percent_Identity=27.8350515463918, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321726, Length=262, Percent_Identity=24.4274809160305, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322241, Length=198, Percent_Identity=26.7676767676768, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6322021, Length=198, Percent_Identity=26.7676767676768, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6324416, Length=198, Percent_Identity=26.7676767676768, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6321731, Length=172, Percent_Identity=28.4883720930233, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319776, Length=172, Percent_Identity=28.4883720930233, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24586599, Length=505, Percent_Identity=24.7524752475248, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586593, Length=508, Percent_Identity=23.8188976377953, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24586589, Length=372, Percent_Identity=26.8817204301075, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24586597, Length=500, Percent_Identity=24.2, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24586591, Length=203, Percent_Identity=28.0788177339901, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45549022, Length=199, Percent_Identity=28.643216080402, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24583747, Length=374, Percent_Identity=25.4010695187166, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583749, Length=374, Percent_Identity=24.8663101604278, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24586587, Length=93, Percent_Identity=40.8602150537634, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583745, Length=236, Percent_Identity=24.1525423728814, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221330053, Length=492, Percent_Identity=21.7479674796748, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004185
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783
- InterPro:   IPR014756
- InterPro:   IPR017069 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02903 Alpha-amylase_N [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 69154; Mature: 69154

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEEMSVPMHKQRSQPQPG
CCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCHHHHCCCCCCC
VTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWA
HHHHHHEEECCCCCCCCEEEEEEEEECCHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCHH
ADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILRDWDEPVTAQAGGSTFYGGDLD
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEECCCCCC
GISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHNTQQLG
CHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHH
MRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPK
HHHEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCCCC
LDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGWRLDVVHMLGEAGGARNNLQHVAGITEA
CCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHHH
AKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFPLWGFLANTDISYDPQQIDAQT
HHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHHHH
CMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGREVARLPLAVVWLFTWPGVPCIY
HHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEE
YGDEVGLDGKNDPFCRKPFPWQVEKQDMALFALYQRMIALRKKSQALRRGGCQVLYAEDN
ECCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
VVVFVRVLNQQRVLVAINRGEACEVVLPASPFLNVVQWQRKEGHGQLTDGILALPAISAT
EEEEEEEECCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEHHHHCEE
VWMN
EECC
>Mature Secondary Structure
MLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEEMSVPMHKQRSQPQPG
CCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCHHHHCCCCCCC
VTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWA
HHHHHHEEECCCCCCCCEEEEEEEEECCHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCHH
ADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILRDWDEPVTAQAGGSTFYGGDLD
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEECCCCCC
GISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHNTQQLG
CHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHH
MRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPK
HHHEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCCCC
LDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGWRLDVVHMLGEAGGARNNLQHVAGITEA
CCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHHH
AKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFPLWGFLANTDISYDPQQIDAQT
HHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHHHH
CMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGREVARLPLAVVWLFTWPGVPCIY
HHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEE
YGDEVGLDGKNDPFCRKPFPWQVEKQDMALFALYQRMIALRKKSQALRRGGCQVLYAEDN
ECCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
VVVFVRVLNQQRVLVAINRGEACEVVLPASPFLNVVQWQRKEGHGQLTDGILALPAISAT
EEEEEEEECCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEHHHHCEE
VWMN
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1918057; 9278503; 1706703 [H]