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The map label for this gene is yneE

Identifier: 209395864

GI number: 209395864

Start: 2046631

End: 2047545

Strand: Reverse

Name: yneE

Synonym: ECH74115_2133

Alternate gene names: 209395864

Gene position: 2047545-2046631 (Counterclockwise)

Preceding gene: 209396611

Following gene: 209397971

Centisome position: 36.75

GC content: 48.2

Gene sequence:

>915_bases
ATGATTGTTCGTCCACAACAACACTGGCTGCGCCGTATTTTTGTCTGGCATGGCTCAGTATTATCCAAGATATCCTCGCG
CTTACTACTCAATTTTCTCTTTTCTATCGCTGTTATTTTCATGCTGCCCTGGTACACGCATCTGGGCATCAAATTCACCC
TCGCACCGTTCAGCATTCTCGGTGTCGCCATCGCCATTTTTCTTGGTTTTCGTAATAATGCCGGTTACGCCCGTTACGTT
GAAGCGCGCAAACTTTGGGGGCAGTTGATGATTGCCTCACGGTCGTTACTGCGCGAGGTAAAAACGACATTGCCGGATTC
GGCAAGTGTAAGGGAGTTTGCCCGGCTGCAAATCGCCTTCGCCCACTGTTTACGCATGACATTACGCAAACAGCCACAGG
TGGAAGTGCTGGCTCATTATCTCAAGACTGAAGATCTTCAGCGTGTACTGGCTTCGAACTCTCCAGCTAACCGCATCTTG
TTAATAATGGGGGAGTGGTTGGCGGTTCAGCGACGCAATGGACAACTTTCAGATATCCTGTTTATTAGCCTCAACGATCG
GCTTAACGATATTTCAGCGGTTCTGGCAGGCTGCGAGCGCATTGCCTACACGCCAATTCCCTTTGCCTACACCCTGATTT
TGCATCGTACCGTTTATCTGTTTTGTATCATGCTGCCGTTCGCGCTGGTCGTGGACCTGCATTACATGACGCCTTTTATC
TCTGTGCTGATTTCCTATACTTTTATTTCGCTGGATTGTCTGGCGGAAGAACTGGAAGATCCGTTCGGTACTGAAAACAA
TGATTTACCGCTGGATGCCATCTGTAACGCTATTGAAATTGACCTCTTACAGATGAACGATGAAGCCGAAATTCCAGCAA
AAGTTCTTCCCGATCGCCATTACCAACTGACGTGA

Upstream 100 bases:

>100_bases
TGTTAATGTTGTAATTTTGTAGGTAATTTGTAAGTAGTGTCTTGAGAATGTGATCGTAATCACGTTTAATAGGGCGACTT
TTCCACGCCTGAAGATAACC

Downstream 100 bases:

>100_bases
TATTTACTCCGTACGGCGGGCAACAATAAACAGACGCGGAAATGCCAGCAGTATCTGTCCGTTCTCTTGCAGTGGATACT
GCTCTTTCAGCATCTGATGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPWYTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYV
EARKLWGQLMIASRSLLREVKTTLPDSASVREFARLQIAFAHCLRMTLRKQPQVEVLAHYLKTEDLQRVLASNSPANRIL
LIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTVYLFCIMLPFALVVDLHYMTPFI
SVLISYTFISLDCLAEELEDPFGTENNDLPLDAICNAIEIDLLQMNDEAEIPAKVLPDRHYQLT

Sequences:

>Translated_304_residues
MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPWYTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYV
EARKLWGQLMIASRSLLREVKTTLPDSASVREFARLQIAFAHCLRMTLRKQPQVEVLAHYLKTEDLQRVLASNSPANRIL
LIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTVYLFCIMLPFALVVDLHYMTPFI
SVLISYTFISLDCLAEELEDPFGTENNDLPLDAICNAIEIDLLQMNDEAEIPAKVLPDRHYQLT
>Mature_304_residues
MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPWYTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYV
EARKLWGQLMIASRSLLREVKTTLPDSASVREFARLQIAFAHCLRMTLRKQPQVEVLAHYLKTEDLQRVLASNSPANRIL
LIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTVYLFCIMLPFALVVDLHYMTPFI
SVLISYTFISLDCLAEELEDPFGTENNDLPLDAICNAIEIDLLQMNDEAEIPAKVLPDRHYQLT

Specific function: Unknown

COG id: COG3781

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0187 family

Homologues:

Organism=Escherichia coli, GI87081925, Length=304, Percent_Identity=99.3421052631579, Blast_Score=620, Evalue=1e-179,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YNEE_ECO57 (Q8XAZ3)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B85723
- PIR:   G90894
- RefSeq:   NP_287634.1
- RefSeq:   NP_310154.1
- EnsemblBacteria:   EBESCT00000027095
- EnsemblBacteria:   EBESCT00000055500
- GeneID:   917350
- GeneID:   960646
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2185
- KEGG:   ecs:ECs2127
- GeneTree:   EBGT00050000010167
- HOGENOM:   HBG520274
- OMA:   RIRSTPV
- ProtClustDB:   CLSK880028
- BioCyc:   ECOL83334:ECS2127-MONOMER
- InterPro:   IPR021134

Pfam domain/function: PF01062 Bestrophin

EC number: NA

Molecular weight: Translated: 34823; Mature: 34823

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2066e024)-; HASH(0x208bb3f0)-; HASH(0x1ef84724)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPWYTHLGIKFTLAPFSIL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHH
GVAIAIFLGFRNNAGYARYVEARKLWGQLMIASRSLLREVKTTLPDSASVREFARLQIAF
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AHCLRMTLRKQPQVEVLAHYLKTEDLQRVLASNSPANRILLIMGEWLAVQRRNGQLSDIL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHCCCCEEEEE
FISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTVYLFCIMLPFALVVDLHYMTPFI
EEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVLISYTFISLDCLAEELEDPFGTENNDLPLDAICNAIEIDLLQMNDEAEIPAKVLPDRH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHEEEEEECCCCCCCHHHCCCCC
YQLT
CCCH
>Mature Secondary Structure
MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPWYTHLGIKFTLAPFSIL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHH
GVAIAIFLGFRNNAGYARYVEARKLWGQLMIASRSLLREVKTTLPDSASVREFARLQIAF
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AHCLRMTLRKQPQVEVLAHYLKTEDLQRVLASNSPANRILLIMGEWLAVQRRNGQLSDIL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHCCCCEEEEE
FISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTVYLFCIMLPFALVVDLHYMTPFI
EEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVLISYTFISLDCLAEELEDPFGTENNDLPLDAICNAIEIDLLQMNDEAEIPAKVLPDRH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHEEEEEECCCCCCCHHHCCCCC
YQLT
CCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796