Click here to switch to the map view.

The map label for this gene is katG

Identifier: 209395777

GI number: 209395777

Start: 5043830

End: 5046010

Strand: Direct

Name: katG

Synonym: ECH74115_5403

Alternate gene names: 209395777

Gene position: 5043830-5046010 (Clockwise)

Preceding gene: 209401006

Following gene: 209396472

Centisome position: 90.52

GC content: 55.89

Gene sequence:

>2181_bases
ATGAGCACGTCAGACGATATCCATAACACGACAGCCACTGGCAAATGCCCGTTCCATCAGGGCGGTCACGACCAGAGCGC
GGGGGCGGGCACAACCACTCGCGACTGGTGGCCAAATCAACTCCGTGTTGACCTGTTAAACCAACATTCTAATCGTTCTA
ACCCGCTGGGTGAGGACTTTGACTACCGCAAAGAATTCAGCAAATTAGATTACTACGGCCTGAAAAAAGATCTGAAAGCC
CTGCTGACAGAATCTCAGCCGTGGTGGCCAGCCGACTGGGGCAGCTACGCCGGTCTGTTTATTCGTATGGCCTGGCACGG
CGCGGGGACTTACCGATCAATCGATGGACGCGGTGGCGCGGGTCGTGGTCAGCAACGTTTTGCACCGCTGAACTCCTGGC
CGGATAACGTAAGCCTCGATAAAGCGCGTCGCTTGTTGTGGCCAATCAAACAGAAATATGGTCAGAAAATCTCCTGGGCC
GACCTGTTTATCCTCGCGGGTAACGTGGCGCTGGAAAACTCCGGCTTCCGTACCTTCGGTTTTGGTGCCGGTCGTGAAGA
CGTCTGGGAACCGGATCTGGATGTTAACTGGGGTGATGAAAAAGCCTGGCTGACTCACCGTCATCCGGAAGCGCTGGCGA
AAGCACCGCTGGGTGCAACCGAGATGGGTCTGATTTACGTTAACCCGGAAGGCCCGGATCACAGCGGCGAACCGCTTTCT
GCGGCAGCAGCTATCCGCGCGACCTTCGGCAACATGGGTATGAACGACGAAGAAACCGTGGCGCTGATTGCGGGTGGTCA
TACGCTGGGTAAAACCCACGGTGCTGGTCCGACATCAAATGTAGGTCCTGATCCAGAAGCTGCGCCGATTGAAGAACAAG
GTTTAGGTTGGGCGAGCACTTACGGCAGCGGCGTTGGCGCAGATGCCATTACCTCTGGTCTGGAAGTGGTCTGGACCCAG
ACGCCGACCCAGTGGAGCAACTATTTCTTCGAGAACCTGTTCAAGTATGAGTGGGTACAGACCCGCAGTCCGGCTGGCGC
AATCCAGTTCGAAGCGGTAGACGCACCGGAAATTATCCCGGATCCGTTCGATCCGTCGAAGAAACGTAAACCGACGATGC
TGGTGACCGACCTGACGCTGCGTTTTGATCCTGAGTTCGAGAAGATCTCTCGTCGTTTCCTCAACGATCCGCAGGCGTTC
AACGAAGCCTTTGCCCGTGCCTGGTTCAAACTGACGCACAGGGATATGGGGCCGAAATCTCGTTACATCGGGCCGGAAGT
ACCGAAAGAAGATCTGATCTGGCAAGATCCGCTGCCGCAGCCGATCTACAACCCGACCGAGCAGGACATTATCGATCTGA
AATTCGCGATTGCGGATTCTGGTCTGTCTGTTAGTGAGCTGGTATCGGTGGCCTGGGCTTCTGCTTCTACCTTCCGTGGT
GGCGACAAACGCGGTGGTGCCAACGGTGCGCGTCTGGCATTAATGCCGCAGCGCGACTGGGATGTGAACGCCGCAGCCGT
TCGTGCTCTGCCTGTTCTGGAGAAAATTCAGAAAGAGTCTGGTAAAGCCTCGCTGGCGGATATCATCGTGCTGGCAGGTG
TGGTTGGCGTTGAGAAAGCCGCAAGCGCCGCTGGTTTGAGCATTCATGTACCGTTTGCGCCGGGTCGCGTTGATGCGCGT
CAGGATCAGACTGACATTGAGATGTTCGAACTGCTGGAGCCAATTGCTGACGGTTTCCGTAACTATCGCGCTCGTCTGGA
TGTTTCCACCACCGAGTCACTGCTGATTGATAAAGCCCAGCAACTGACCCTGACCGCGCCGGAAATGACCGCGCTGGTGG
GCGGGATGCGTGTACTGGGTGCCAACTTCGATGGCAGCAAAAACGGCGTCTTCACTGACCGCGTTGGCGTATTGAGCAAT
GACTTCTTCGTGAACTTGCTGGATATGCGTTACGAGTGGAAAGCGACCGACGAATCGAAAGAGCTGTTCGAAGGCCGTGA
CCGCGAAACCGGCGAAGTGAAATACACTGCCAGCCGTGCGGATCTGGTATTTGGTTCTAACTCTGTCCTGCGTGCGGTGG
CTGAAGTTTACGCCAGCAGCGATGCTCACGAGAAGTTTGTTAAAGACTTCGTGGCGGCATGGGTGAAAGTGATGAACCTC
GACCGTTTCGACCTGCTGTAA

Upstream 100 bases:

>100_bases
TATGTAAGATCTCAACTATCGCATCCGTGGATTAATTCAATTATAACTTCTCTCTAACGCTGTGTATCGTAACGGTAACA
CTGTAGAGGGGAGCACATTG

Downstream 100 bases:

>100_bases
TCTGACCTTCTTCAGCGACTGCCTTTCAGGCAGTCGCTGAAGTTTCTTTACCGGCGTATAGTGTCCACAGGAAAACTACA
CACTGGATCTCTCATGTCTG

Product: catalase/peroxidase HPI

Products: NA

Alternate protein names: CP 1; Peroxidase/catalase 1

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKA
LLTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLS
AAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQ
TPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAF
NEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRG
GDKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDAR
QDQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFDGSKNGVFTDRVGVLSN
DFFVNLLDMRYEWKATDESKELFEGRDRETGEVKYTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNL
DRFDLL

Sequences:

>Translated_726_residues
MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKA
LLTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLS
AAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQ
TPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAF
NEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRG
GDKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDAR
QDQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFDGSKNGVFTDRVGVLSN
DFFVNLLDMRYEWKATDESKELFEGRDRETGEVKYTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNL
DRFDLL
>Mature_725_residues
STSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKAL
LTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWAD
LFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLSA
AAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQT
PTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFN
EAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRGG
DKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDARQ
DQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFDGSKNGVFTDRVGVLSND
FFVNLLDMRYEWKATDESKELFEGRDRETGEVKYTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNLD
RFDLL

Specific function: Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity

COG id: COG0376

COG function: function code P; Catalase (peroxidase I)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peroxidase family. Peroxidase/catalase subfamily

Homologues:

Organism=Escherichia coli, GI1790378, Length=726, Percent_Identity=99.8622589531681, Blast_Score=1484, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KATG1_ECO57 (Q7A978)

Other databases:

- EMBL:   BA000007
- EMBL:   AE005174
- PIR:   C86085
- PIR:   G91237
- RefSeq:   NP_290579.1
- RefSeq:   NP_312898.1
- HSSP:   P13029
- ProteinModelPortal:   Q7A978
- SMR:   Q7A978
- PeroxiBase:   2718
- EnsemblBacteria:   EBESCT00000025740
- EnsemblBacteria:   EBESCT00000057213
- GeneID:   915019
- GeneID:   960189
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5497
- KEGG:   ecs:ECs4871
- GeneTree:   EBGT00050000011618
- HOGENOM:   HBG285610
- OMA:   FEWELTK
- ProtClustDB:   PRK15061
- BioCyc:   ECOL83334:ECS4871-MONOMER
- HAMAP:   MF_01961
- InterPro:   IPR000763
- InterPro:   IPR010255
- InterPro:   IPR002016
- InterPro:   IPR019794
- InterPro:   IPR019793
- PRINTS:   PR00460
- PRINTS:   PR00458
- TIGRFAMs:   TIGR00198

Pfam domain/function: PF00141 peroxidase; SSF48113 Peroxidase_super

EC number: =1.11.1.6; =1.11.1.7

Molecular weight: Translated: 80040; Mature: 79909

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00435 PEROXIDASE_1; PS00436 PEROXIDASE_2; PS50873 PEROXIDASE_4

Important sites: ACT_SITE 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
DYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEEEEEEECCCCCEEECCCCCCC
GRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCEEEC
FGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLS
CCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHH
AAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWAST
HHHHHHHHHCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCHHH
YGSGVGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIP
CCCCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
DPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKS
CCCCCCCCCCCEEEEEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
RYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRG
CCCCCCCCHHCCCCCCCCCCCCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHCCHHCCC
GDKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKA
CCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ASAAGLSIHVPFAPGRVDARQDQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQ
HCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHCCH
QLTLTAPEMTALVGGMRVLGANFDGSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESK
HEEEECHHHHHHHCCHHEEECCCCCCCCCEEECCCCCCCCCCEEEEECCEEEECCCCCHH
ELFEGRDRETGEVKYTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNL
HHHCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
DRFDLL
CHHHCC
>Mature Secondary Structure 
STSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
DYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEEEEEEECCCCCEEECCCCCCC
GRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCEEEC
FGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLS
CCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHH
AAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWAST
HHHHHHHHHCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCHHH
YGSGVGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIP
CCCCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
DPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKS
CCCCCCCCCCCEEEEEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
RYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRG
CCCCCCCCHHCCCCCCCCCCCCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHCCHHCCC
GDKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKA
CCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ASAAGLSIHVPFAPGRVDARQDQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQ
HCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHCCH
QLTLTAPEMTALVGGMRVLGANFDGSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESK
HEEEECHHHHHHHCCHHEEECCCCCCCCCEEECCCCCCCCCCEEEEECCEEEECCCCCHH
ELFEGRDRETGEVKYTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNL
HHHCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
DRFDLL
CHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11258796; 11206551