Click here to switch to the map view.

The map label for this gene is yeaP [H]

Identifier: 209696224

GI number: 209696224

Start: 3053485

End: 3054483

Strand: Direct

Name: yeaP [H]

Synonym: VSAL_I2820

Alternate gene names: 209696224

Gene position: 3053485-3054483 (Clockwise)

Preceding gene: 209696219

Following gene: 209696225

Centisome position: 91.83

GC content: 37.34

Gene sequence:

>999_bases
ATGGATGTGCGTATGACAGCGTTTTTCACTTCTCATTTTGATTCACAAGACAACATTATTGACCTATCAAAATGGCAAGA
ACTTGCAGATTTAATTGTTGATATTTTTGGGGCCGACTGTGGTGCCGTTATCGAATTTACAGGTCATTCTTTCCATACCC
TTATAAGCAGCAATAATAAAACAAATTTTCTTCGCCAAGGTTCTGAATGGCCTAGTGACAGCAAAAGCTTTTGTCGTGCC
ATTGTAGAAACAGGCAAAGAGTTATATGTACCTGATGCGTTAAAGAACGAATATTGGATTAATGCCCCAGCAGTTGAAGA
TGGCCCAGTAAGATCTTATTGTGGTGTTCCTGTCTTTCACCCTGATGGCTCTATTTATGGCACTATTTGTGCGATAGATA
CAAAGCATACTAATTATAAAAGTGCATTAGTTAAGCTACTGCATCACCTGTCAAAGCTCATTACGGCTGATTTGAAAATG
GCAGAAGAAGCTGAGCAACATCGACAAATGGCACTTACCGATTCAATGACAGGGTTACTTAATCGTCGTGGATTAGACAT
TCTAGGTAAGCAGAAATTAAAAGATTCAAAAAGGTACCAAGATAATATTGGCATCCTATATTTTGATATTGATAATTTAA
AACAAGTAAATGACAACCATGGCCACGAATTCGGAGATCAATGCATTCAACTATTGGCCAATATTTTAAAAAGCACAATC
AGAGAATCCGATTTAACCGCTCGTACTGGCGGGGATGAATTTATTGTTTTAGCCTTGCTGAATAAGGAAAACGACAATGA
ACTTGCCTTACTCGCAGAACAAATCCGCCAACGTTACCAAGAAAAAACGATGCATCAACCAGGCTTAAACCTCACCAATA
TTAGTATTGGTCGTCATCTTGAACCTTATGATTCAGTACTATCACTTAAAGACATGTTCATTAATACAGATACCGCTATG
TATAAAGAAAAAGATCAAAAAAAAGCCACCAGTAAATAA

Upstream 100 bases:

>100_bases
AAAAGGTAAATGATTTGATTTTGAACCTAATGACAATGAAATTAACATTTAATAATGATAGTTTTATAACTATACAAAAT
TCAAATAATTATAGCCCTAC

Downstream 100 bases:

>100_bases
TCTATAAAAATAAAAAATAACTATTACATATCAGTAAAGGTGATTTTCTATTTAAGGCTATTATCACTATTATAGAAACA
AATATAATACTCACATTGAA

Product: hypothetical protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MDVRMTAFFTSHFDSQDNIIDLSKWQELADLIVDIFGADCGAVIEFTGHSFHTLISSNNKTNFLRQGSEWPSDSKSFCRA
IVETGKELYVPDALKNEYWINAPAVEDGPVRSYCGVPVFHPDGSIYGTICAIDTKHTNYKSALVKLLHHLSKLITADLKM
AEEAEQHRQMALTDSMTGLLNRRGLDILGKQKLKDSKRYQDNIGILYFDIDNLKQVNDNHGHEFGDQCIQLLANILKSTI
RESDLTARTGGDEFIVLALLNKENDNELALLAEQIRQRYQEKTMHQPGLNLTNISIGRHLEPYDSVLSLKDMFINTDTAM
YKEKDQKKATSK

Sequences:

>Translated_332_residues
MDVRMTAFFTSHFDSQDNIIDLSKWQELADLIVDIFGADCGAVIEFTGHSFHTLISSNNKTNFLRQGSEWPSDSKSFCRA
IVETGKELYVPDALKNEYWINAPAVEDGPVRSYCGVPVFHPDGSIYGTICAIDTKHTNYKSALVKLLHHLSKLITADLKM
AEEAEQHRQMALTDSMTGLLNRRGLDILGKQKLKDSKRYQDNIGILYFDIDNLKQVNDNHGHEFGDQCIQLLANILKSTI
RESDLTARTGGDEFIVLALLNKENDNELALLAEQIRQRYQEKTMHQPGLNLTNISIGRHLEPYDSVLSLKDMFINTDTAM
YKEKDQKKATSK
>Mature_332_residues
MDVRMTAFFTSHFDSQDNIIDLSKWQELADLIVDIFGADCGAVIEFTGHSFHTLISSNNKTNFLRQGSEWPSDSKSFCRA
IVETGKELYVPDALKNEYWINAPAVEDGPVRSYCGVPVFHPDGSIYGTICAIDTKHTNYKSALVKLLHHLSKLITADLKM
AEEAEQHRQMALTDSMTGLLNRRGLDILGKQKLKDSKRYQDNIGILYFDIDNLKQVNDNHGHEFGDQCIQLLANILKSTI
RESDLTARTGGDEFIVLALLNKENDNELALLAEQIRQRYQEKTMHQPGLNLTNISIGRHLEPYDSVLSLKDMFINTDTAM
YKEKDQKKATSK

Specific function: Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger (Probable). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081977, Length=253, Percent_Identity=28.8537549407115, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786584, Length=171, Percent_Identity=29.8245614035088, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693134, Length=155, Percent_Identity=34.1935483870968, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787541, Length=181, Percent_Identity=34.2541436464088, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87081974, Length=160, Percent_Identity=30.625, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787262, Length=196, Percent_Identity=27.5510204081633, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87081881, Length=161, Percent_Identity=33.5403726708075, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=190, Percent_Identity=31.0526315789474, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082007, Length=114, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=31.875, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR003018 [H]

Pfam domain/function: PF01590 GAF; PF00990 GGDEF [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 37575; Mature: 37575

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRMTAFFTSHFDSQDNIIDLSKWQELADLIVDIFGADCGAVIEFTGHSFHTLISSNNK
CCCEEEEHHHHCCCCCCCEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHCCCCCC
TNFLRQGSEWPSDSKSFCRAIVETGKELYVPDALKNEYWINAPAVEDGPVRSYCGVPVFH
CHHHHCCCCCCCCHHHHHHHHHHCCCEEECCHHHCCCEEECCCCCCCCCCHHHCCCEEEC
PDGSIYGTICAIDTKHTNYKSALVKLLHHLSKLITADLKMAEEAEQHRQMALTDSMTGLL
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRRGLDILGKQKLKDSKRYQDNIGILYFDIDNLKQVNDNHGHEFGDQCIQLLANILKSTI
HCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RESDLTARTGGDEFIVLALLNKENDNELALLAEQIRQRYQEKTMHQPGLNLTNISIGRHL
HHCCCCEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
EPYDSVLSLKDMFINTDTAMYKEKDQKKATSK
CHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDVRMTAFFTSHFDSQDNIIDLSKWQELADLIVDIFGADCGAVIEFTGHSFHTLISSNNK
CCCEEEEHHHHCCCCCCCEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHCCCCCC
TNFLRQGSEWPSDSKSFCRAIVETGKELYVPDALKNEYWINAPAVEDGPVRSYCGVPVFH
CHHHHCCCCCCCCHHHHHHHHHHCCCEEECCHHHCCCEEECCCCCCCCCCHHHCCCEEEC
PDGSIYGTICAIDTKHTNYKSALVKLLHHLSKLITADLKMAEEAEQHRQMALTDSMTGLL
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRRGLDILGKQKLKDSKRYQDNIGILYFDIDNLKQVNDNHGHEFGDQCIQLLANILKSTI
HCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RESDLTARTGGDEFIVLALLNKENDNELALLAEQIRQRYQEKTMHQPGLNLTNISIGRHL
HHCCCCEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
EPYDSVLSLKDMFINTDTAMYKEKDQKKATSK
CHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]