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The map label for this gene is dipZ [H]

Identifier: 209696215

GI number: 209696215

Start: 3042841

End: 3044715

Strand: Direct

Name: dipZ [H]

Synonym: VSAL_I2811

Alternate gene names: 209696215

Gene position: 3042841-3044715 (Clockwise)

Preceding gene: 209696214

Following gene: 209696216

Centisome position: 91.51

GC content: 41.81

Gene sequence:

>1875_bases
ATGACGAATTTACTCCGATTTAGAGCCGCCCTTTTATCATTCTTCATTTTATTTGCGTCCTTTGCACCCCAAGCGGTTGC
GGCTTTTGATTTAACTAAACTACAAAATCAACAAGACTCTTCTTTTGTGACCGTAAATGAAGCCTTCCCATTCAACTTCA
TGCAACAAGGGGATCGCGTCTATTTAGATTGGCAAGTAAAACCTGATTATTACTTATATCAGCAGCGTATTTCAGTCTCA
GCGCATGATGCTAACATTGCCGACTTAGTCATGGAACAAGGCACGCCTCATAACGATGAATTTTTTGGTGATGTTAATAT
CTACACCAAGCCATTGACCATCACTGTGCCACTCATCTCAGTCGATAAAGATGCAGAGCTAACCGTTCGTTATCAAGGGT
GTGCAAAAGCAGGATTCTGTTATCCACCAGAAATCCGTAAAATCCCATTATCCATGCTCACAGCCTCAAGCTCAAGCTCA
TACCAAAACGAAACGGCAAATACTCATGTGGTAGCCAAAAGCGAAACCGCACCAGTGAGCGTAGAAAAAGCGACATCACC
ATCGGTAAATAGTCTAAATACCGCTGGTATTCAACAACCAAAAAATCAAACTCAACAGCAAGCGCTTGCAAGCGATCTGG
GTGATGCTTGGTGGACTCCGTTTTTATTCTTAGCGTTAGGTATTGGTCTTGCGTTTACTCCTTGTGTGTTACCTATGTAC
CCTATTTTAACGGGCATTGTTTTAGGTGGCGGTAAACTTTCTCACGGTAAAGCCTTCAAACTGTCTTTTGTCTATGTTCA
AGGCATGGCTCTTACTTACACCTTACTTGGGTTAGTCGTTGCTTCTGCCGGTCTACAATTCCAAGCAGCATTACAACATC
CCTACGTTCTTATTGGTTTGAGTGTGATGTTTGTGCTGTTGGCACTGTCCATGTTTGGTGTTTACACCATTCAATTACCA
AGCAGCTTACAAACCAAATTAAACGACATCAGTAACCAACAAAAAGGCGGTAACTTAGGTGGCGTATTTGCGATGGGTGC
GATCTCTGGTTTAGTGTGCTCACCATGTACGACTGCACCACTGTCTGGTGCGTTACTTTATGTAGCAAAAAGTGGGGACT
TACTAACAGGCGCTGTTGCGTTGTATGCCTTAGCGATTGGTATGGGTATCCCATTAATTTTAGCCGCAGTATTTGGTAAT
AAGCTACTACCAAAAGCAGGCGTATGGATGACGTATGTGAAAACCCTATTTGGTTTTATTCTTCTCGCGGTTCCAGTCTT
CTTATTAGAGCGAATTCTTCCTCATAACATCACGCCATTTATTTGGTCTGCTCTTGGGATCGTAGCATTTGGTTGGTTAT
ATCATGTCAAAGCAACGATGCCCCAATCATGGAAAACAAGTGTTGCTGGTATCATCGCTATTTTAGGTATCGTCGGCTCA
GCTATTCCTGTCATCGATGCCATATCAGGGAAAACATCGAGCCAAGTTGCCACTACTCAAGCGGTAGCCTTTAAGCGCAT
CTCTACTATTGATGAATTAAACAAAGAGCTTAAGGTAGCAAAAATTCAAGGCAAGCCTGTGATGCTCGATTTCTATGCAG
ATTGGTGTGTCGCTTGTAAAGAATTTGAAAAATACACCTTTCATGATGAAAACGTTGAACCGTTACTATCCAACTTTATT
TTGTTGCAAGCCGATGTCACCAAAAACAGCCCAGTTGATATTGAATTATTAAAACAACTTAAGGTGTTAGGTTTGCCTAC
CATAGATTTTTGGAATGCAAATGGCGATTATTTATCAGACTCTCGTCTTACGGGATTCATGAAAGCAGAGCCGTTTATTC
AGCATTTGCAACAAAATGTGAGCTTGGTTGAATAA

Upstream 100 bases:

>100_bases
AAAACGGATCATAGATGTTAGTGCGAATTGATATTATACTTGCTGAACTCTTGACCATTTCGATAGTCATATCCGTATCT
ATTTTTATAAAGACCCCCAC

Downstream 100 bases:

>100_bases
TTTTGCTCCTTTATTGACCAAAATCATTAGCATTACGAAGGTACTTATTTTACAATGCGAATTAACGCAATTAAGCGAAC
AATTACATTAATTTTTTGAG

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 624; Mature: 623

Protein sequence:

>624_residues
MTNLLRFRAALLSFFILFASFAPQAVAAFDLTKLQNQQDSSFVTVNEAFPFNFMQQGDRVYLDWQVKPDYYLYQQRISVS
AHDANIADLVMEQGTPHNDEFFGDVNIYTKPLTITVPLISVDKDAELTVRYQGCAKAGFCYPPEIRKIPLSMLTASSSSS
YQNETANTHVVAKSETAPVSVEKATSPSVNSLNTAGIQQPKNQTQQQALASDLGDAWWTPFLFLALGIGLAFTPCVLPMY
PILTGIVLGGGKLSHGKAFKLSFVYVQGMALTYTLLGLVVASAGLQFQAALQHPYVLIGLSVMFVLLALSMFGVYTIQLP
SSLQTKLNDISNQQKGGNLGGVFAMGAISGLVCSPCTTAPLSGALLYVAKSGDLLTGAVALYALAIGMGIPLILAAVFGN
KLLPKAGVWMTYVKTLFGFILLAVPVFLLERILPHNITPFIWSALGIVAFGWLYHVKATMPQSWKTSVAGIIAILGIVGS
AIPVIDAISGKTSSQVATTQAVAFKRISTIDELNKELKVAKIQGKPVMLDFYADWCVACKEFEKYTFHDENVEPLLSNFI
LLQADVTKNSPVDIELLKQLKVLGLPTIDFWNANGDYLSDSRLTGFMKAEPFIQHLQQNVSLVE

Sequences:

>Translated_624_residues
MTNLLRFRAALLSFFILFASFAPQAVAAFDLTKLQNQQDSSFVTVNEAFPFNFMQQGDRVYLDWQVKPDYYLYQQRISVS
AHDANIADLVMEQGTPHNDEFFGDVNIYTKPLTITVPLISVDKDAELTVRYQGCAKAGFCYPPEIRKIPLSMLTASSSSS
YQNETANTHVVAKSETAPVSVEKATSPSVNSLNTAGIQQPKNQTQQQALASDLGDAWWTPFLFLALGIGLAFTPCVLPMY
PILTGIVLGGGKLSHGKAFKLSFVYVQGMALTYTLLGLVVASAGLQFQAALQHPYVLIGLSVMFVLLALSMFGVYTIQLP
SSLQTKLNDISNQQKGGNLGGVFAMGAISGLVCSPCTTAPLSGALLYVAKSGDLLTGAVALYALAIGMGIPLILAAVFGN
KLLPKAGVWMTYVKTLFGFILLAVPVFLLERILPHNITPFIWSALGIVAFGWLYHVKATMPQSWKTSVAGIIAILGIVGS
AIPVIDAISGKTSSQVATTQAVAFKRISTIDELNKELKVAKIQGKPVMLDFYADWCVACKEFEKYTFHDENVEPLLSNFI
LLQADVTKNSPVDIELLKQLKVLGLPTIDFWNANGDYLSDSRLTGFMKAEPFIQHLQQNVSLVE
>Mature_623_residues
TNLLRFRAALLSFFILFASFAPQAVAAFDLTKLQNQQDSSFVTVNEAFPFNFMQQGDRVYLDWQVKPDYYLYQQRISVSA
HDANIADLVMEQGTPHNDEFFGDVNIYTKPLTITVPLISVDKDAELTVRYQGCAKAGFCYPPEIRKIPLSMLTASSSSSY
QNETANTHVVAKSETAPVSVEKATSPSVNSLNTAGIQQPKNQTQQQALASDLGDAWWTPFLFLALGIGLAFTPCVLPMYP
ILTGIVLGGGKLSHGKAFKLSFVYVQGMALTYTLLGLVVASAGLQFQAALQHPYVLIGLSVMFVLLALSMFGVYTIQLPS
SLQTKLNDISNQQKGGNLGGVFAMGAISGLVCSPCTTAPLSGALLYVAKSGDLLTGAVALYALAIGMGIPLILAAVFGNK
LLPKAGVWMTYVKTLFGFILLAVPVFLLERILPHNITPFIWSALGIVAFGWLYHVKATMPQSWKTSVAGIIAILGIVGSA
IPVIDAISGKTSSQVATTQAVAFKRISTIDELNKELKVAKIQGKPVMLDFYADWCVACKEFEKYTFHDENVEPLLSNFIL
LQADVTKNSPVDIELLKQLKVLGLPTIDFWNANGDYLSDSRLTGFMKAEPFIQHLQQNVSLVE

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=581, Percent_Identity=50.4302925989673, Blast_Score=551, Evalue=1e-158,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 67847; Mature: 67715

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLLRFRAALLSFFILFASFAPQAVAAFDLTKLQNQQDSSFVTVNEAFPFNFMQQGDRV
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHCCCCEE
YLDWQVKPDYYLYQQRISVSAHDANIADLVMEQGTPHNDEFFGDVNIYTKPLTITVPLIS
EEEEEECCCHHHHHHHHEEECCCCHHHHHHHHCCCCCCCCEEECEEEEECCEEEEEEEEE
VDKDAELTVRYQGCAKAGFCYPPEIRKIPLSMLTASSSSSYQNETANTHVVAKSETAPVS
ECCCCEEEEEECCCCCCCCCCCCHHHHCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCE
VEKATSPSVNSLNTAGIQQPKNQTQQQALASDLGDAWWTPFLFLALGIGLAFTPCVLPMY
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
PILTGIVLGGGKLSHGKAFKLSFVYVQGMALTYTLLGLVVASAGLQFQAALQHPYVLIGL
HHHHHHHCCCCEECCCCEEEEEEEEEHHHHHHHHHHHHHHHHCCCCEEHHHCCCCHHHHH
SVMFVLLALSMFGVYTIQLPSSLQTKLNDISNQQKGGNLGGVFAMGAISGLVCSPCTTAP
HHHHHHHHHHHHCEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
LSGALLYVAKSGDLLTGAVALYALAIGMGIPLILAAVFGNKLLPKAGVWMTYVKTLFGFI
CCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LLAVPVFLLERILPHNITPFIWSALGIVAFGWLYHVKATMPQSWKTSVAGIIAILGIVGS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AIPVIDAISGKTSSQVATTQAVAFKRISTIDELNKELKVAKIQGKPVMLDFYADWCVACK
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEHHHHHHHHH
EFEKYTFHDENVEPLLSNFILLQADVTKNSPVDIELLKQLKVLGLPTIDFWNANGDYLSD
HHHHCCCCCCCHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCC
SRLTGFMKAEPFIQHLQQNVSLVE
CCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TNLLRFRAALLSFFILFASFAPQAVAAFDLTKLQNQQDSSFVTVNEAFPFNFMQQGDRV
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHCCCCEE
YLDWQVKPDYYLYQQRISVSAHDANIADLVMEQGTPHNDEFFGDVNIYTKPLTITVPLIS
EEEEEECCCHHHHHHHHEEECCCCHHHHHHHHCCCCCCCCEEECEEEEECCEEEEEEEEE
VDKDAELTVRYQGCAKAGFCYPPEIRKIPLSMLTASSSSSYQNETANTHVVAKSETAPVS
ECCCCEEEEEECCCCCCCCCCCCHHHHCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCE
VEKATSPSVNSLNTAGIQQPKNQTQQQALASDLGDAWWTPFLFLALGIGLAFTPCVLPMY
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
PILTGIVLGGGKLSHGKAFKLSFVYVQGMALTYTLLGLVVASAGLQFQAALQHPYVLIGL
HHHHHHHCCCCEECCCCEEEEEEEEEHHHHHHHHHHHHHHHHCCCCEEHHHCCCCHHHHH
SVMFVLLALSMFGVYTIQLPSSLQTKLNDISNQQKGGNLGGVFAMGAISGLVCSPCTTAP
HHHHHHHHHHHHCEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
LSGALLYVAKSGDLLTGAVALYALAIGMGIPLILAAVFGNKLLPKAGVWMTYVKTLFGFI
CCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LLAVPVFLLERILPHNITPFIWSALGIVAFGWLYHVKATMPQSWKTSVAGIIAILGIVGS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AIPVIDAISGKTSSQVATTQAVAFKRISTIDELNKELKVAKIQGKPVMLDFYADWCVACK
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEHHHHHHHHH
EFEKYTFHDENVEPLLSNFILLQADVTKNSPVDIELLKQLKVLGLPTIDFWNANGDYLSD
HHHHCCCCCCCHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCC
SRLTGFMKAEPFIQHLQQNVSLVE
CCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]