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The map label for this gene is hflX [H]

Identifier: 209696182

GI number: 209696182

Start: 3005754

End: 3007073

Strand: Reverse

Name: hflX [H]

Synonym: VSAL_I2776

Alternate gene names: 209696182

Gene position: 3007073-3005754 (Counterclockwise)

Preceding gene: 209696183

Following gene: 209696181

Centisome position: 90.43

GC content: 41.29

Gene sequence:

>1320_bases
TTGTTTGACCGTTATGAATCCGGTGAACAGGCTATTCTTGTGCACATCAGCTTTACTTATGAAGGGGAGTTGGAAGATCT
CAACGAGTGTAAAATGTTGATATCTTCTGCTGGAGCCAACACATTAGGTGTTGTGACGGGGACCCGTCAATCTCCGCTCC
CTAAATATTATGTTGGTTTAGGTAAAGCACAAGAAATTGCCAATATGGTTCGAGCTAAGAATGCGGATATTGTGATTTTT
AATCATGCGCTTTCTCCTGCTCAAGAACGAAATTTAGAGGCATTATGTGAATGTCGAGTGATAGACCGTAATGGGTTAAT
ACTGGATATTTTTGCTCAACGTGCACGAACCTATGAAGGTAAGTTGCAAGTCGAGCTCGCACAATTACGTCATATATCTA
CTCGATTGATCCGAGGATGGACACACCTTGAACGCCAAAAAGGCGGGATTGGTTTACGTGGTCCTGGTGAAACTCAGTTG
GAAAGCGATAGACGATTATTACGAGATCGTATTAAAGCAATTCAACGTCGATTGGCTAAAGTCGCAAAACAACGCGAACA
AGGTCGTCGGGCAAGATATCGTGCAGAAATCCCAACCATTTCTTTAGTTGGTTATACTAACGCAGGTAAATCTACGTTAT
TTAATCGAATTACAGATGCGGGGGTTTATGCCGCTGACCAGCTGTTTGCTACGCTTGATCCTACATTACGTAAGATAGAC
GTTACAGATGTTGGTACAGCAATACTTGCTGATACGGTGGGCTTTATACGTCATTTACCTCATGATCTTGTTGCCGCGTT
TAAAGCGACACTTCAAGAAACGCAAGAAGCAAATATCTTGTTACATGTTGTTGATGCCAGTGATGAACGCTTTCGTGAGA
ACATTGAAGCGGTAGATATTGTTCTAGAAGAGATAGATGCCAATGAGGTACCTTATCTTCTCGTAATGAATAAGATTGAT
GACTTAGAAGATCAACAACCACGAATTGACCGTGATGAAGAGGGCGTTCCTCGATGTGTTTGGGTTTCAGCAATGGAAGG
CGAAGGCATTGATTTACTTTTTCAAGCATTAACGGAGCGATTAGCAGGGCAGATGGTAGAGCATACATTGCGGTTACCTC
CTGAATTGGTTGGGCGTTTTCGAAGTAAATTCTTTCAAATGCAAAGCATTATAAAAGAAGAATATCAGGATGATGGCAGC
TTGCTTATTGATATACGTATGCAGCAAGTTGATTGGTCTAAGTTAGAAAAACGTGAAGAGACTCCGTTAAGTTATTTTTT
AATGACTGACGAGAGTACACCGAATTCTTTATCTTCATAA

Upstream 100 bases:

>100_bases
ACACTGCTAGTGATCGACCACAAGGCGAGCGCCCACAAGAAACAACAGAAGAGTAAGACTATTTTATTTTTAAATAGACA
ATCTGTTAAGGAGTTAGCGC

Downstream 100 bases:

>100_bases
TTACTTTGGAGTTTTCTAATGGCGTGGAATGAGCCTGGAAATAACAACAATAACGACAAGAACGGCGGTGGCGATAATAA
AGACCCTTGGGGTAATAAAA

Product: GTPase HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MFDRYESGEQAILVHISFTYEGELEDLNECKMLISSAGANTLGVVTGTRQSPLPKYYVGLGKAQEIANMVRAKNADIVIF
NHALSPAQERNLEALCECRVIDRNGLILDIFAQRARTYEGKLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQL
ESDRRLLRDRIKAIQRRLAKVAKQREQGRRARYRAEIPTISLVGYTNAGKSTLFNRITDAGVYAADQLFATLDPTLRKID
VTDVGTAILADTVGFIRHLPHDLVAAFKATLQETQEANILLHVVDASDERFRENIEAVDIVLEEIDANEVPYLLVMNKID
DLEDQQPRIDRDEEGVPRCVWVSAMEGEGIDLLFQALTERLAGQMVEHTLRLPPELVGRFRSKFFQMQSIIKEEYQDDGS
LLIDIRMQQVDWSKLEKREETPLSYFLMTDESTPNSLSS

Sequences:

>Translated_439_residues
MFDRYESGEQAILVHISFTYEGELEDLNECKMLISSAGANTLGVVTGTRQSPLPKYYVGLGKAQEIANMVRAKNADIVIF
NHALSPAQERNLEALCECRVIDRNGLILDIFAQRARTYEGKLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQL
ESDRRLLRDRIKAIQRRLAKVAKQREQGRRARYRAEIPTISLVGYTNAGKSTLFNRITDAGVYAADQLFATLDPTLRKID
VTDVGTAILADTVGFIRHLPHDLVAAFKATLQETQEANILLHVVDASDERFRENIEAVDIVLEEIDANEVPYLLVMNKID
DLEDQQPRIDRDEEGVPRCVWVSAMEGEGIDLLFQALTERLAGQMVEHTLRLPPELVGRFRSKFFQMQSIIKEEYQDDGS
LLIDIRMQQVDWSKLEKREETPLSYFLMTDESTPNSLSS
>Mature_439_residues
MFDRYESGEQAILVHISFTYEGELEDLNECKMLISSAGANTLGVVTGTRQSPLPKYYVGLGKAQEIANMVRAKNADIVIF
NHALSPAQERNLEALCECRVIDRNGLILDIFAQRARTYEGKLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQL
ESDRRLLRDRIKAIQRRLAKVAKQREQGRRARYRAEIPTISLVGYTNAGKSTLFNRITDAGVYAADQLFATLDPTLRKID
VTDVGTAILADTVGFIRHLPHDLVAAFKATLQETQEANILLHVVDASDERFRENIEAVDIVLEEIDANEVPYLLVMNKID
DLEDQQPRIDRDEEGVPRCVWVSAMEGEGIDLLFQALTERLAGQMVEHTLRLPPELVGRFRSKFFQMQSIIKEEYQDDGS
LLIDIRMQQVDWSKLEKREETPLSYFLMTDESTPNSLSS

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=216, Percent_Identity=36.1111111111111, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI310133118, Length=218, Percent_Identity=35.7798165137615, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI310124269, Length=204, Percent_Identity=36.2745098039216, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI310124267, Length=204, Percent_Identity=36.2745098039216, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI310124171, Length=204, Percent_Identity=36.2745098039216, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI310124169, Length=204, Percent_Identity=36.2745098039216, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1790615, Length=427, Percent_Identity=70.4918032786885, Blast_Score=625, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17561038, Length=344, Percent_Identity=26.453488372093, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24650079, Length=282, Percent_Identity=30.8510638297872, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49768; Mature: 49768

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYESGEQAILVHISFTYEGELEDLNECKMLISSAGANTLGVVTGTRQSPLPKYYVGL
CCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCC
GKAQEIANMVRAKNADIVIFNHALSPAQERNLEALCECRVIDRNGLILDIFAQRARTYEG
CHHHHHHHHHHCCCCCEEEEECCCCCHHHCCHHHHHHEEEECCCCCEEHHHHHHHHCCCC
KLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQLESDRRLLRDRIKAIQRRLAK
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VAKQREQGRRARYRAEIPTISLVGYTNAGKSTLFNRITDAGVYAADQLFATLDPTLRKID
HHHHHHHHHHHHEEECCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHEEE
VTDVGTAILADTVGFIRHLPHDLVAAFKATLQETQEANILLHVVDASDERFRENIEAVDI
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
VLEEIDANEVPYLLVMNKIDDLEDQQPRIDRDEEGVPRCVWVSAMEGEGIDLLFQALTER
HHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
LAGQMVEHTLRLPPELVGRFRSKFFQMQSIIKEEYQDDGSLLIDIRMQQVDWSKLEKREE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCC
TPLSYFLMTDESTPNSLSS
CCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MFDRYESGEQAILVHISFTYEGELEDLNECKMLISSAGANTLGVVTGTRQSPLPKYYVGL
CCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCC
GKAQEIANMVRAKNADIVIFNHALSPAQERNLEALCECRVIDRNGLILDIFAQRARTYEG
CHHHHHHHHHHCCCCCEEEEECCCCCHHHCCHHHHHHEEEECCCCCEEHHHHHHHHCCCC
KLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQLESDRRLLRDRIKAIQRRLAK
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VAKQREQGRRARYRAEIPTISLVGYTNAGKSTLFNRITDAGVYAADQLFATLDPTLRKID
HHHHHHHHHHHHEEECCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHEEE
VTDVGTAILADTVGFIRHLPHDLVAAFKATLQETQEANILLHVVDASDERFRENIEAVDI
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
VLEEIDANEVPYLLVMNKIDDLEDQQPRIDRDEEGVPRCVWVSAMEGEGIDLLFQALTER
HHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
LAGQMVEHTLRLPPELVGRFRSKFFQMQSIIKEEYQDDGSLLIDIRMQQVDWSKLEKREE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCC
TPLSYFLMTDESTPNSLSS
CCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]