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The map label for this gene is aroK [H]

Identifier: 209696128

GI number: 209696128

Start: 2948361

End: 2948879

Strand: Direct

Name: aroK [H]

Synonym: VSAL_I2722

Alternate gene names: 209696128

Gene position: 2948361-2948879 (Clockwise)

Preceding gene: 209696126

Following gene: 209696129

Centisome position: 88.67

GC content: 42.77

Gene sequence:

>519_bases
ATGGCTGAAAAACGAAATATTTTCCTTGTTGGCCCAATGGGCGCCGGCAAAAGTACAATTGGTAGGCACTTAGCACAGCA
ACTTCACATGGAGTTTCTTGATTCTGATACGGTAATTGAAGAACGCACAGGCGCAGATATCGCTTGGGTATTCGACGTTG
AAGGTGAAGAAGGTTTCCGTATACGTGAGGAAGGTGTAATTAACGATTTAACTCAAGAGCAAGGTATTGTACTTGCGACG
GGTGGTGGCTCTGTAATTAGTAAAGAGAGTCGCAATCGTTTATCTGCTCGTGGTGTTGTTGTATATCTTGAAACTACGAT
TGAGAAGCAATTAGCTCGCACACAACGCGATAAAAAACGTCCGTTGCTTCAAACTGATGAGCCTCGAGAAGTGTTAGAAG
CACTAGCGAAAGAACGTAACGCACTTTATGAAGAAGTGTCTGATTACGTTGTTCGTACCGATGATCAAAGTGCAAAAGTG
GTAGCAAATCAAATCATCCAAATGCTTGAAGAGCGTTAA

Upstream 100 bases:

>100_bases
TCACGAAATATCTGTGAGGAATATGGTGCCACAGAAGCATGTCTGTTGAAGAGACAACTGTTGGCAATGTCGTTAATGAA
CTTTGCATAATTTCTAAAAA

Downstream 100 bases:

>100_bases
TTCAAGTCATTTTATAAGACGGATATTGGGAACGAATCATGGAAACGATTCATGTAGATTTAGCAGAACGTAGCTATCCC
ATCTCTATCGGCGCCGAGTT

Product: shikimate kinase I

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MAEKRNIFLVGPMGAGKSTIGRHLAQQLHMEFLDSDTVIEERTGADIAWVFDVEGEEGFRIREEGVINDLTQEQGIVLAT
GGGSVISKESRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQTDEPREVLEALAKERNALYEEVSDYVVRTDDQSAKV
VANQIIQMLEER

Sequences:

>Translated_172_residues
MAEKRNIFLVGPMGAGKSTIGRHLAQQLHMEFLDSDTVIEERTGADIAWVFDVEGEEGFRIREEGVINDLTQEQGIVLAT
GGGSVISKESRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQTDEPREVLEALAKERNALYEEVSDYVVRTDDQSAKV
VANQIIQMLEER
>Mature_171_residues
AEKRNIFLVGPMGAGKSTIGRHLAQQLHMEFLDSDTVIEERTGADIAWVFDVEGEEGFRIREEGVINDLTQEQGIVLATG
GGSVISKESRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQTDEPREVLEALAKERNALYEEVSDYVVRTDDQSAKVV
ANQIIQMLEER

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=171, Percent_Identity=82.4561403508772, Blast_Score=283, Evalue=4e-78,
Organism=Escherichia coli, GI1786587, Length=159, Percent_Identity=30.8176100628931, Blast_Score=89, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320332, Length=154, Percent_Identity=33.1168831168831, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19357; Mature: 19226

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKRNIFLVGPMGAGKSTIGRHLAQQLHMEFLDSDTVIEERTGADIAWVFDVEGEEGFR
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEECCCCCCE
IREEGVINDLTQEQGIVLATGGGSVISKESRNRLSARGVVVYLETTIEKQLARTQRDKKR
ECCCCCHHHHHHHCCEEEEECCCCEECHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHCC
PLLQTDEPREVLEALAKERNALYEEVSDYVVRTDDQSAKVVANQIIQMLEER
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEKRNIFLVGPMGAGKSTIGRHLAQQLHMEFLDSDTVIEERTGADIAWVFDVEGEEGFR
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEECCCCCCE
IREEGVINDLTQEQGIVLATGGGSVISKESRNRLSARGVVVYLETTIEKQLARTQRDKKR
ECCCCCHHHHHHHCCEEEEECCCCEECHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHCC
PLLQTDEPREVLEALAKERNALYEEVSDYVVRTDDQSAKVVANQIIQMLEER
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA