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The map label for this gene is nahR [H]

Identifier: 209695869

GI number: 209695869

Start: 2617733

End: 2618659

Strand: Direct

Name: nahR [H]

Synonym: VSAL_I2445

Alternate gene names: 209695869

Gene position: 2617733-2618659 (Clockwise)

Preceding gene: 209695866

Following gene: 209695870

Centisome position: 78.72

GC content: 36.57

Gene sequence:

>927_bases
ATGGCAAAAGATCTCTTTGCAACGTTAGATTTAAACTTACTAAGAACTTTTTTAATTCTCTCTCAAGAATTGAATATGCG
AAAAGCTTCTGAGCGTTTATTTGTGTCTCAACCCGCAATCAGCCAAGCATTACAAAAGCTGCGTAATCATTTTGATGACG
AGCTCTTTGTGAAAGTTCATCATGGCCTAAAAGCTACGCCATTTTCTGAAGAGTTAGCGGAAAGCATTCACCCTTATCTT
GATGGATTATCATCGGTATTAAATACCTCAAAAAACTTTCAGCCAAGCGAGTTACAACAGACACTAAAAATAGCACTGGC
TCCTCAAGTATTGACCTGCCTATCTGGTGCTTTATTTCACGAAATAAGAGAAAACGCGCCTAATGTCGACTTACAATTAT
TTAATTGGTCAGCATCAACCTTCAGCGATCTAACCAAAGGAAAGCTAGATATCGCGATTAATTATGAGTATGACAACGTT
CCAAAAGAGCTCATTTCAAGTAACTTAATGACTATTAAAGGCTGTGTGATTGTTAGAACCGATCACCCAATAAAAAAACA
AATAGCAACCCCTCATGACTTTGAAGGATATGAACTTGCCTCTTTAATTATTCCAGGTTGGAACGATAATAAAAGTCTCG
CAGGTAAAGTCTTAGAAAATTTAAATATCAAACATAAAATTGGTTTTCGCTCAGAGTTACCAATGGCGTTAATTGATGTT
GTTCAACATACTAATATGTATTTTCCTTCAACGTCGTTGTTTCCTACTCACCAGTACTTAGGCTTAAGGCGCATTGATCT
TGCACTGGATCATATTCCTTTAAATTACCCTATTTACAGCTATTACCATCAAAGACATAAGAAAAACGCGTTGCACTCGT
GGCTAAATCAACTCATTACTGATTTATTATCTGATGCCCACCACTAA

Upstream 100 bases:

>100_bases
CATACTTTTTCATCATAAATTCAATACAATAAGAAGAGTTAACGAAGGATGCGTGAAGAGTTATTTAATAACTCAATTTA
TTGATAGGAAATAAGTAGAT

Downstream 100 bases:

>100_bases
ATACTTATAAATAAAGGGTAAAACAAACCAAATAATAAGCAGTACTTATTATTGATATAATAACTGGTGATTAGAAAGTA
ATCACCATTCTCAATATTAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MAKDLFATLDLNLLRTFLILSQELNMRKASERLFVSQPAISQALQKLRNHFDDELFVKVHHGLKATPFSEELAESIHPYL
DGLSSVLNTSKNFQPSELQQTLKIALAPQVLTCLSGALFHEIRENAPNVDLQLFNWSASTFSDLTKGKLDIAINYEYDNV
PKELISSNLMTIKGCVIVRTDHPIKKQIATPHDFEGYELASLIIPGWNDNKSLAGKVLENLNIKHKIGFRSELPMALIDV
VQHTNMYFPSTSLFPTHQYLGLRRIDLALDHIPLNYPIYSYYHQRHKKNALHSWLNQLITDLLSDAHH

Sequences:

>Translated_308_residues
MAKDLFATLDLNLLRTFLILSQELNMRKASERLFVSQPAISQALQKLRNHFDDELFVKVHHGLKATPFSEELAESIHPYL
DGLSSVLNTSKNFQPSELQQTLKIALAPQVLTCLSGALFHEIRENAPNVDLQLFNWSASTFSDLTKGKLDIAINYEYDNV
PKELISSNLMTIKGCVIVRTDHPIKKQIATPHDFEGYELASLIIPGWNDNKSLAGKVLENLNIKHKIGFRSELPMALIDV
VQHTNMYFPSTSLFPTHQYLGLRRIDLALDHIPLNYPIYSYYHQRHKKNALHSWLNQLITDLLSDAHH
>Mature_307_residues
AKDLFATLDLNLLRTFLILSQELNMRKASERLFVSQPAISQALQKLRNHFDDELFVKVHHGLKATPFSEELAESIHPYLD
GLSSVLNTSKNFQPSELQQTLKIALAPQVLTCLSGALFHEIRENAPNVDLQLFNWSASTFSDLTKGKLDIAINYEYDNVP
KELISSNLMTIKGCVIVRTDHPIKKQIATPHDFEGYELASLIIPGWNDNKSLAGKVLENLNIKHKIGFRSELPMALIDVV
QHTNMYFPSTSLFPTHQYLGLRRIDLALDHIPLNYPIYSYYHQRHKKNALHSWLNQLITDLLSDAHH

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=300, Percent_Identity=25.3333333333333, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081684, Length=310, Percent_Identity=22.9032258064516, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786820, Length=277, Percent_Identity=26.3537906137184, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35118; Mature: 34987

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDLFATLDLNLLRTFLILSQELNMRKASERLFVSQPAISQALQKLRNHFDDELFVKVH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEC
HGLKATPFSEELAESIHPYLDGLSSVLNTSKNFQPSELQQTLKIALAPQVLTCLSGALFH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRENAPNVDLQLFNWSASTFSDLTKGKLDIAINYEYDNVPKELISSNLMTIKGCVIVRT
HHHHCCCCCEEEEEECCCHHHHHHCCCCEEEEEEECCCCCHHHHHCCCCEEEEEEEEEEC
DHPIKKQIATPHDFEGYELASLIIPGWNDNKSLAGKVLENLNIKHKIGFRSELPMALIDV
CCCHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCCCHHHHHH
VQHTNMYFPSTSLFPTHQYLGLRRIDLALDHIPLNYPIYSYYHQRHKKNALHSWLNQLIT
HHHCCCCCCCCCCCCCHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLLSDAHH
HHHHCCCC
>Mature Secondary Structure 
AKDLFATLDLNLLRTFLILSQELNMRKASERLFVSQPAISQALQKLRNHFDDELFVKVH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEC
HGLKATPFSEELAESIHPYLDGLSSVLNTSKNFQPSELQQTLKIALAPQVLTCLSGALFH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRENAPNVDLQLFNWSASTFSDLTKGKLDIAINYEYDNVPKELISSNLMTIKGCVIVRT
HHHHCCCCCEEEEEECCCHHHHHHCCCCEEEEEEECCCCCHHHHHCCCCEEEEEEEEEEC
DHPIKKQIATPHDFEGYELASLIIPGWNDNKSLAGKVLENLNIKHKIGFRSELPMALIDV
CCCHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCCCHHHHHH
VQHTNMYFPSTSLFPTHQYLGLRRIDLALDHIPLNYPIYSYYHQRHKKNALHSWLNQLIT
HHHCCCCCCCCCCCCCHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLLSDAHH
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]