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The map label for this gene is cutC

Identifier: 209695866

GI number: 209695866

Start: 2615595

End: 2616338

Strand: Direct

Name: cutC

Synonym: VSAL_I2442

Alternate gene names: 209695866

Gene position: 2615595-2616338 (Clockwise)

Preceding gene: 209695865

Following gene: 209695869

Centisome position: 78.66

GC content: 40.73

Gene sequence:

>744_bases
ATGCCTATCCAAATTGAAGTCTGTATCGACAACTTAGAATCTCTGCATAATGCGATAAATGGTGGTGCCGATAGAATTGA
GCTTTGCTCTTCCCTTGCTCTCGGTGGTTTAACACCAAGCTTTGGTTTTATGAAAAAAGCAGCAGCGATCTCTTCTGTTC
CGGTTTATGCCATGATCCGTCCTCGTCAAGGCGATTTTCTCTATGATAATGATGATATCTCCGCCATGATTGAAGACATT
CATGCAGCTAAACTAGCTGGTTTACAGGGCGTTGTATTTGGGGTGCTAAAAGCAAACGGTGATATCGACATGCCGTTGTC
CACTCGATTGATGAAAATAGCGAATGATAATGACTTGGGTGTGACTTTCCACCGTGCTGTAGATCAATGTTCCAATTATA
AAAAAGCGATTGAGAACATTGCTGAGTTAGGTTGTGAGAGAATACTCACGTCAGGATTAGCGGCGAATGCTTATGATGGT
ATGACAGTATTAAATGATATGGTAAAACTGGCTAATGGCCGCTTTAAAATACTTGCAGGAGCTGGTGTCACCGCAGAAAA
TGCCAAAGAGATCATTGAAAAAACAGGCGTTACTGAAATTCATTTATCAGGTAAATCAACACGCCCAAGTAAAATGAAAT
TGATGCTAGACGGCGTAAAAATGGGGGCCGGTGATTTAGATGATTTTATTGTCCCTGTTACTGACTCTAAAAAAATCGAT
GCGGTAAGACAAAACATCAAATAA

Upstream 100 bases:

>100_bases
AATCTCTTAATCTGCTCATCAATTTTGACGTACTCTTCACACATCCAAAGTCGACTTTCCCTTACACTAAAAAATTCTCT
ATTATTTTGACTAAACTCTC

Downstream 100 bases:

>100_bases
ATACACTATAAAATAAAAAGGCCAGAGAATTATCTCTGGCCTTTTTCATCGAAAACAATCAGCTCATTATTTTGCTAGTT
GAACCGTATTTACATCAACG

Product: copper homeostasis protein CutC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MPIQIEVCIDNLESLHNAINGGADRIELCSSLALGGLTPSFGFMKKAAAISSVPVYAMIRPRQGDFLYDNDDISAMIEDI
HAAKLAGLQGVVFGVLKANGDIDMPLSTRLMKIANDNDLGVTFHRAVDQCSNYKKAIENIAELGCERILTSGLAANAYDG
MTVLNDMVKLANGRFKILAGAGVTAENAKEIIEKTGVTEIHLSGKSTRPSKMKLMLDGVKMGAGDLDDFIVPVTDSKKID
AVRQNIK

Sequences:

>Translated_247_residues
MPIQIEVCIDNLESLHNAINGGADRIELCSSLALGGLTPSFGFMKKAAAISSVPVYAMIRPRQGDFLYDNDDISAMIEDI
HAAKLAGLQGVVFGVLKANGDIDMPLSTRLMKIANDNDLGVTFHRAVDQCSNYKKAIENIAELGCERILTSGLAANAYDG
MTVLNDMVKLANGRFKILAGAGVTAENAKEIIEKTGVTEIHLSGKSTRPSKMKLMLDGVKMGAGDLDDFIVPVTDSKKID
AVRQNIK
>Mature_246_residues
PIQIEVCIDNLESLHNAINGGADRIELCSSLALGGLTPSFGFMKKAAAISSVPVYAMIRPRQGDFLYDNDDISAMIEDIH
AAKLAGLQGVVFGVLKANGDIDMPLSTRLMKIANDNDLGVTFHRAVDQCSNYKKAIENIAELGCERILTSGLAANAYDGM
TVLNDMVKLANGRFKILAGAGVTAENAKEIIEKTGVTEIHLSGKSTRPSKMKLMLDGVKMGAGDLDDFIVPVTDSKKIDA
VRQNIK

Specific function: Involved in copper homeostasis

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family

Homologues:

Organism=Homo sapiens, GI148596990, Length=246, Percent_Identity=43.9024390243902, Blast_Score=199, Evalue=2e-51,
Organism=Escherichia coli, GI87081995, Length=224, Percent_Identity=37.9464285714286, Blast_Score=162, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17556905, Length=224, Percent_Identity=40.1785714285714, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21355415, Length=237, Percent_Identity=36.2869198312236, Blast_Score=139, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CUTC_ALISL (B6EK72)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263796.1
- ProteinModelPortal:   B6EK72
- GeneID:   6987753
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2442
- HOGENOM:   HBG535337
- OMA:   PVYAMIR
- ProtClustDB:   CLSK874089
- GO:   GO:0005737
- HAMAP:   MF_00795
- InterPro:   IPR005627
- Gene3D:   G3DSA:3.20.20.380
- PANTHER:   PTHR12598

Pfam domain/function: PF03932 CutC; SSF110395 CutC

EC number: NA

Molecular weight: Translated: 26470; Mature: 26339

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIQIEVCIDNLESLHNAINGGADRIELCSSLALGGLTPSFGFMKKAAAISSVPVYAMIR
CCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEE
PRQGDFLYDNDDISAMIEDIHAAKLAGLQGVVFGVLKANGDIDMPLSTRLMKIANDNDLG
CCCCCEEECCCHHHHHHHHHHHHHHHCHHHHHHEEEECCCCCCCCHHHHHHHHCCCCCCC
VTFHRAVDQCSNYKKAIENIAELGCERILTSGLAANAYDGMTVLNDMVKLANGRFKILAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEC
AGVTAENAKEIIEKTGVTEIHLSGKSTRPSKMKLMLDGVKMGAGDLDDFIVPVTDSKKID
CCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHEEEEECCCCCCCCCCCEEEECCCCHHHH
AVRQNIK
HHHHCCC
>Mature Secondary Structure 
PIQIEVCIDNLESLHNAINGGADRIELCSSLALGGLTPSFGFMKKAAAISSVPVYAMIR
CEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEE
PRQGDFLYDNDDISAMIEDIHAAKLAGLQGVVFGVLKANGDIDMPLSTRLMKIANDNDLG
CCCCCEEECCCHHHHHHHHHHHHHHHCHHHHHHEEEECCCCCCCCHHHHHHHHCCCCCCC
VTFHRAVDQCSNYKKAIENIAELGCERILTSGLAANAYDGMTVLNDMVKLANGRFKILAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEC
AGVTAENAKEIIEKTGVTEIHLSGKSTRPSKMKLMLDGVKMGAGDLDDFIVPVTDSKKID
CCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHEEEEECCCCCCCCCCCEEEECCCCHHHH
AVRQNIK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA