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The map label for this gene is malX [H]

Identifier: 209695116

GI number: 209695116

Start: 1722394

End: 1723971

Strand: Reverse

Name: malX [H]

Synonym: VSAL_I1615

Alternate gene names: 209695116

Gene position: 1723971-1722394 (Counterclockwise)

Preceding gene: 209695120

Following gene: 209695115

Centisome position: 51.85

GC content: 41.25

Gene sequence:

>1578_bases
ATGCAGCAAAAAGCGAATAAAACGACGTTATGGGAGTTCTTACAAAGCTTAGGGAAAACCTTTATGGTTCCTGTTGCTTT
GCTTGCATTCTCGGGTATCTTACTCGGTATCGGGAGTTCTTTTTCAAGTGCGGCATTAAAAGAAGCAATGCCATTTTTTG
ATAATGTTATCTTCCAGTATTTATTTATATGGATGACCAAAATTGGTTTAGTTGCGTTTATTTATCTGCCTGTCATGTTT
GCGATTGCGATTCCTATGGGTCTTGCTCGTGAAGAGAAAGGGGTGGCTGCATTCTCGGGTTTAGTTGGTTACGCAGCATT
AAATTTAGCGGTTAACTTCTACCTAACGGTGAACGGTGTACTTGATAATGAAGTACTACGTGAAGCTTACGGTGTGAAAT
CTATCTTAGGGACCGAATCGATTGATACGGGTATTTTAGGGGCGGTTATCGTTGGTATTATCGTTGCTAAGCTGCATGTT
CGCTTCTACACATTTAAAATGCCTGATGCATTGGCTTTCTTTGGTGGTGCTCGTTTTGTTCCTATTATCTCAACCATTAC
GTTAGGTGTTGTTGGTTTATTGGTTCCTTTTATTTGGCCTTACTTTGCGGCAGGTATTAATGGTATTGGTCATGTAATTG
CTGGTGCCGGTGATTTTGGTCCTTTCTTATTTGGCATGAGCGAACGTCTACTTTTACCTATTGGTCTTCATCATATTTTA
GTTGCGCTTATCCGTTTTACTGAAGCGGGCGGTACGATGGAAGTGTGTGGTGATACGGTGTCTGGTGCATTAAACATTTT
CTATTCAGAGCTTTCTTGTTCTGAAACTCAAGGCTTTACTCCATCAGTTACTGCTTTCTTATCTCAAGGTAAAATGCCTG
CGTTCTTAGGTGGCCTTCCTGGTGCCGCTTTAGCGATGTACCATTGTGCTAAAGTTGAAAACCGCAGCAAGATTAAAGCG
TTATTAGTTTCTGGTGTGGTTGCTTGTATTGTTGGTGGTATCACCGAACCTCTTGAGTTCTTGTTCCTATTCGTTGCGCC
AGTTTTGTATTTTATCCACGTAATTTTAACTGGCTTTGGCTTCATGATCATGGGGATGCTAGACGTTACTATTGGTAATA
CCGATGGCAACATTATTGATTTCTTAGTCTTTGGTGTACTTCAGGGGATGTCTACTAAATGGTACTTAGTTCCTGTGGTT
GCAGGTGTTTGGTTCGCGGTTTATTACTTTGTATTTAAGTTCGCAATTCTTAAGTTCAACCTTAAAACTCCGGGCCGTGA
AGCTGAAGATATTGCGATGTCTAGAGAAGAAGCGGCGATTATTGCCACGGCTGGTGGTAAAGGTAAACTTATCCTTGCTG
CACTTGGTGGTGCAGAAAATATCACGTCATTAGACAACTGTATTACACGTTTACGCATGACGGTTGAAGACATGAGTTTG
GTTGACGATGCACAGCTCAAACTGTATGGGGCGCTTGGTGTGGTTAAGCTTGATCAACATAGCTTGCAGGTTGTTATTGG
TGCGCAAGTTCATATTGTTAAAAATGAAATGCAATCATTAATGTCAGCAACAGCTTAA

Upstream 100 bases:

>100_bases
AAATACTCATTTTAATACCATATGGATATATGGATATATGGTAAAGGCGAAATCTTCATTCTCGAAAACTTATCATTAAC
TACTTAATTAAGGATATTTT

Downstream 100 bases:

>100_bases
TTTTTATAGGTGGAGGTTCTCTCCACCTTTTTCACACTCTTTGTTTTTTAGTTCACATAAATATGAGCTTTTGGAGTCGC
TATGTTTACTTTCTCTGAGC

Product: bifunctional PTS system maltose and glucose-specific transporter subunits IICB

Products: NA

Alternate protein names: Maltose and glucose permease IIC component; PTS system maltose- and glucose-specific EIIC component; Maltose- and glucose-specific phosphotransferase enzyme IIB component; PTS system maltose- and glucose-specific EIIB component [H]

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MQQKANKTTLWEFLQSLGKTFMVPVALLAFSGILLGIGSSFSSAALKEAMPFFDNVIFQYLFIWMTKIGLVAFIYLPVMF
AIAIPMGLAREEKGVAAFSGLVGYAALNLAVNFYLTVNGVLDNEVLREAYGVKSILGTESIDTGILGAVIVGIIVAKLHV
RFYTFKMPDALAFFGGARFVPIISTITLGVVGLLVPFIWPYFAAGINGIGHVIAGAGDFGPFLFGMSERLLLPIGLHHIL
VALIRFTEAGGTMEVCGDTVSGALNIFYSELSCSETQGFTPSVTAFLSQGKMPAFLGGLPGAALAMYHCAKVENRSKIKA
LLVSGVVACIVGGITEPLEFLFLFVAPVLYFIHVILTGFGFMIMGMLDVTIGNTDGNIIDFLVFGVLQGMSTKWYLVPVV
AGVWFAVYYFVFKFAILKFNLKTPGREAEDIAMSREEAAIIATAGGKGKLILAALGGAENITSLDNCITRLRMTVEDMSL
VDDAQLKLYGALGVVKLDQHSLQVVIGAQVHIVKNEMQSLMSATA

Sequences:

>Translated_525_residues
MQQKANKTTLWEFLQSLGKTFMVPVALLAFSGILLGIGSSFSSAALKEAMPFFDNVIFQYLFIWMTKIGLVAFIYLPVMF
AIAIPMGLAREEKGVAAFSGLVGYAALNLAVNFYLTVNGVLDNEVLREAYGVKSILGTESIDTGILGAVIVGIIVAKLHV
RFYTFKMPDALAFFGGARFVPIISTITLGVVGLLVPFIWPYFAAGINGIGHVIAGAGDFGPFLFGMSERLLLPIGLHHIL
VALIRFTEAGGTMEVCGDTVSGALNIFYSELSCSETQGFTPSVTAFLSQGKMPAFLGGLPGAALAMYHCAKVENRSKIKA
LLVSGVVACIVGGITEPLEFLFLFVAPVLYFIHVILTGFGFMIMGMLDVTIGNTDGNIIDFLVFGVLQGMSTKWYLVPVV
AGVWFAVYYFVFKFAILKFNLKTPGREAEDIAMSREEAAIIATAGGKGKLILAALGGAENITSLDNCITRLRMTVEDMSL
VDDAQLKLYGALGVVKLDQHSLQVVIGAQVHIVKNEMQSLMSATA
>Mature_525_residues
MQQKANKTTLWEFLQSLGKTFMVPVALLAFSGILLGIGSSFSSAALKEAMPFFDNVIFQYLFIWMTKIGLVAFIYLPVMF
AIAIPMGLAREEKGVAAFSGLVGYAALNLAVNFYLTVNGVLDNEVLREAYGVKSILGTESIDTGILGAVIVGIIVAKLHV
RFYTFKMPDALAFFGGARFVPIISTITLGVVGLLVPFIWPYFAAGINGIGHVIAGAGDFGPFLFGMSERLLLPIGLHHIL
VALIRFTEAGGTMEVCGDTVSGALNIFYSELSCSETQGFTPSVTAFLSQGKMPAFLGGLPGAALAMYHCAKVENRSKIKA
LLVSGVVACIVGGITEPLEFLFLFVAPVLYFIHVILTGFGFMIMGMLDVTIGNTDGNIIDFLVFGVLQGMSTKWYLVPVV
AGVWFAVYYFVFKFAILKFNLKTPGREAEDIAMSREEAAIIATAGGKGKLILAALGGAENITSLDNCITRLRMTVEDMSL
VDDAQLKLYGALGVVKLDQHSLQVVIGAQVHIVKNEMQSLMSATA

Specific function: MalX encodes a phosphotransferase system enzyme II that can recognize glucose and maltose as substrates even though these sugars may not represent the natural substrates of the system [H]

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=526, Percent_Identity=66.9201520912547, Blast_Score=706, Evalue=0.0,
Organism=Escherichia coli, GI1787343, Length=510, Percent_Identity=35.8823529411765, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI1786894, Length=514, Percent_Identity=33.852140077821, Blast_Score=223, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011301 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 56342; Mature: 56342

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQKANKTTLWEFLQSLGKTFMVPVALLAFSGILLGIGSSFSSAALKEAMPFFDNVIFQY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LFIWMTKIGLVAFIYLPVMFAIAIPMGLAREEKGVAAFSGLVGYAALNLAVNFYLTVNGV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEECCC
LDNEVLREAYGVKSILGTESIDTGILGAVIVGIIVAKLHVRFYTFKMPDALAFFGGARFV
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHCCCHHH
PIISTITLGVVGLLVPFIWPYFAAGINGIGHVIAGAGDFGPFLFGMSERLLLPIGLHHIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHH
VALIRFTEAGGTMEVCGDTVSGALNIFYSELSCSETQGFTPSVTAFLSQGKMPAFLGGLP
HHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHCCCC
GAALAMYHCAKVENRSKIKALLVSGVVACIVGGITEPLEFLFLFVAPVLYFIHVILTGFG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FMIMGMLDVTIGNTDGNIIDFLVFGVLQGMSTKWYLVPVVAGVWFAVYYFVFKFAILKFN
HHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
LKTPGREAEDIAMSREEAAIIATAGGKGKLILAALGGAENITSLDNCITRLRMTVEDMSL
CCCCCCCHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
VDDAQLKLYGALGVVKLDQHSLQVVIGAQVHIVKNEMQSLMSATA
HCCCHHEEEECCCEEEECCCCEEEEECCEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MQQKANKTTLWEFLQSLGKTFMVPVALLAFSGILLGIGSSFSSAALKEAMPFFDNVIFQY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LFIWMTKIGLVAFIYLPVMFAIAIPMGLAREEKGVAAFSGLVGYAALNLAVNFYLTVNGV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEECCC
LDNEVLREAYGVKSILGTESIDTGILGAVIVGIIVAKLHVRFYTFKMPDALAFFGGARFV
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHCCCHHH
PIISTITLGVVGLLVPFIWPYFAAGINGIGHVIAGAGDFGPFLFGMSERLLLPIGLHHIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHH
VALIRFTEAGGTMEVCGDTVSGALNIFYSELSCSETQGFTPSVTAFLSQGKMPAFLGGLP
HHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHCCCC
GAALAMYHCAKVENRSKIKALLVSGVVACIVGGITEPLEFLFLFVAPVLYFIHVILTGFG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FMIMGMLDVTIGNTDGNIIDFLVFGVLQGMSTKWYLVPVVAGVWFAVYYFVFKFAILKFN
HHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
LKTPGREAEDIAMSREEAAIIATAGGKGKLILAALGGAENITSLDNCITRLRMTVEDMSL
CCCCCCCHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
VDDAQLKLYGALGVVKLDQHSLQVVIGAQVHIVKNEMQSLMSATA
HCCCHHEEEECCCEEEECCCCEEEEECCEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856179; 9097039; 9278503; 2670898 [H]