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The map label for this gene is fabA

Identifier: 209695059

GI number: 209695059

Start: 1667298

End: 1667816

Strand: Reverse

Name: fabA

Synonym: VSAL_I1556

Alternate gene names: 209695059

Gene position: 1667816-1667298 (Counterclockwise)

Preceding gene: 209695060

Following gene: 209695046

Centisome position: 50.16

GC content: 41.23

Gene sequence:

>519_bases
ATGCAAAACAAACCTAGTTCATATGATCGCGAAGATTTACTAGCATCAAGCCGTGGCGAACTATTTGGTCCAAATGGCCC
ACAATTACCAGCTCCAAACATGTTGATGATGGATCGTATTCCACTAATGTCTGAAACTGAAGGTTTATTTGGTAAAGGCA
AAGTTATCGCTGAACTAGATATTACTCCAGACTTATGGTTCTTTGATTGTCACTTCCCTGGTGATCCAGTAATGCCTGGT
TGTCTTGGTTTAGATGCGATGTGGCAACTTGTTGGCTTCTTCCTTGGTTGGGTTGGTGGTCAAGGTAAAGGGCGAGCTCT
TGGTGTTGGTGAAGTTAAATTCACAGGACAAGTACTCCCTACTGCTAAAAAAGTAACGTATGAAATCGACTTTAAACGTG
TTATCAATCGTAAATTGGTAATGGGTTTAGCTGATGGCCGCGTTCTTGTGGATGGCAAAGAAATCTATGTTGCAAAAGAT
TTAAAAGTGGGCCTTTTCCAAGATACGTCTGCATTCTAA

Upstream 100 bases:

>100_bases
TTTGTCGTATTAAGAACTGGTTTAACCAGAGCTGATCAGACTTGATAAGCGTACAAGTGTTCGCTAGAATATCCATAACT
TATTTAGGAGTAATACTTTA

Downstream 100 bases:

>100_bases
TTAAATCATTATTGATTGAATTACTTAAAGCTAGCACTATGGTAGCTTTATTTTTGGAACACACAAGCAAGTTATAGTGC
GCTAGTTAAACTAGTTTAAT

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MQNKPSSYDREDLLASSRGELFGPNGPQLPAPNMLMMDRIPLMSETEGLFGKGKVIAELDITPDLWFFDCHFPGDPVMPG
CLGLDAMWQLVGFFLGWVGGQGKGRALGVGEVKFTGQVLPTAKKVTYEIDFKRVINRKLVMGLADGRVLVDGKEIYVAKD
LKVGLFQDTSAF

Sequences:

>Translated_172_residues
MQNKPSSYDREDLLASSRGELFGPNGPQLPAPNMLMMDRIPLMSETEGLFGKGKVIAELDITPDLWFFDCHFPGDPVMPG
CLGLDAMWQLVGFFLGWVGGQGKGRALGVGEVKFTGQVLPTAKKVTYEIDFKRVINRKLVMGLADGRVLVDGKEIYVAKD
LKVGLFQDTSAF
>Mature_172_residues
MQNKPSSYDREDLLASSRGELFGPNGPQLPAPNMLMMDRIPLMSETEGLFGKGKVIAELDITPDLWFFDCHFPGDPVMPG
CLGLDAMWQLVGFFLGWVGGQGKGRALGVGEVKFTGQVLPTAKKVTYEIDFKRVINRKLVMGLADGRVLVDGKEIYVAKD
LKVGLFQDTSAF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily

Homologues:

Organism=Escherichia coli, GI1787187, Length=172, Percent_Identity=79.6511627906977, Blast_Score=282, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABA_ALISL (B6ELS3)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262988.1
- GeneID:   6989114
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I1556
- HOGENOM:   HBG433282
- OMA:   CHFKGDP
- ProtClustDB:   PRK05174
- GO:   GO:0005737
- HAMAP:   MF_00405
- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114
- PANTHER:   PTHR11712
- TIGRFAMs:   TIGR01749

Pfam domain/function: PF07977 FabA

EC number: =4.2.1.60

Molecular weight: Translated: 18886; Mature: 18886

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: ACT_SITE 71-71

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNKPSSYDREDLLASSRGELFGPNGPQLPAPNMLMMDRIPLMSETEGLFGKGKVIAELD
CCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEE
ITPDLWFFDCHFPGDPVMPGCLGLDAMWQLVGFFLGWVGGQGKGRALGVGEVKFTGQVLP
CCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEECCEECC
TAKKVTYEIDFKRVINRKLVMGLADGRVLVDGKEIYVAKDLKVGLFQDTSAF
CCEEEEEEEHHHHHHCHHEEEEECCCEEEEECCEEEEEECCEEEEECCCCCC
>Mature Secondary Structure
MQNKPSSYDREDLLASSRGELFGPNGPQLPAPNMLMMDRIPLMSETEGLFGKGKVIAELD
CCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEE
ITPDLWFFDCHFPGDPVMPGCLGLDAMWQLVGFFLGWVGGQGKGRALGVGEVKFTGQVLP
CCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEECCEECC
TAKKVTYEIDFKRVINRKLVMGLADGRVLVDGKEIYVAKDLKVGLFQDTSAF
CCEEEEEEEHHHHHHCHHEEEEECCCEEEEECCEEEEEECCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA