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The map label for this gene is sdaC [H]

Identifier: 209694873

GI number: 209694873

Start: 1459080

End: 1460330

Strand: Reverse

Name: sdaC [H]

Synonym: VSAL_I1344

Alternate gene names: 209694873

Gene position: 1460330-1459080 (Counterclockwise)

Preceding gene: 209694874

Following gene: 209694872

Centisome position: 43.92

GC content: 42.05

Gene sequence:

>1251_bases
ATGCAAACAACAACGACTGCATCGACAGGTGCAAAAAAAGCAAAGTGGACTTATAAAGACTTCACTTGGTGTCTTTCTCT
ATTCGGTACAGCCGTAGGTGCTGGTGTTTTATTCCTTCCAATTAAAGCGGGTGCGGGTGGTTTTTGGCCTCTTGTTATTC
TTGCTCTAATCGCTGCACCAATGACTTGGTTTGCACACAAAAGTTTGGCTCGTTTTGTTCTTTCTGCTAAGAACCCAGAC
GCTGATATTACCGATACGGTAGAAGAGCATTTTGGTAAAACTGGCGCAAACCTAATCACTTTTGCTTACTTTTTTGCGAT
TTACCCAATTGTATTAATTTACGGTGTTGGTATTACCAATACAGTCGACTCTTTCATGGTTAACCAAATGGGGATGGAAT
CCATTCCTCGTTGGTTATTATCAGGTGTTCTTATCACTCTGATGACATGTGGCGTTGTATTTGGTAAAGAACTTATGCTG
AAAGCAACATCAGCAATGGTTTACCCTCTTGTTTTCATTTTGATGGTTCTTTCTGTATACCTAATCCCTGAGTGGAACAC
ATCAATGGCGTCTGTAGCACCAGATTGGAGCGCAATGCCTTCTGTTGTTTGGTTAGCGATTCCAATCATCGTTTTCTCTT
TTAACCACAGCCCAGTGATCAGCCAGTTCTCTAAAGAACAACGTCGTGTTTACGGTGAAAATGCAGTAGCAAAAACTGAC
ATGATCACTGGCGGTGCAGCAATGATGCTAATGAGCTTTGTTATGTTCTTCGTTTTCTCTGTGGTTCTTTCTTTATCTCC
AGAGCAACTAGCACAAGCACAAGCACAGAACATCTCTGTTCTTTCTTACCTAGCTAACGTTCACGAATCTCCAATGATTT
CTATCATGGGTCCTGTTGTTGCATTTGCAGCGATTACTTCAAGCTACTTCGGTCACTTCCTTGGCGCTCATGAAGGTCTT
GTTGGTTTAACTAAGTCTCACACAAAAGCACCTCTTGCTACTGTTGAGAAAGGGTCTCTAATCTTCATCGTTGTGACTAC
TTGGATCGTTTCTATCGTTAACCCAAGCATCTTGGGTATGATTGAAACAATGGGTGCACCAATGATTGCCGCTATCCTAT
TCCTAATGCCTGTATTCGCAATGCGTAAAGTACCAGCAATGGCGAAGTACAAAACTTCAGCACCTGTACAAATCTTCACA
GCATTATGTGGTGTTGCTGCGATTACTTCTGTAATCTACGGCGCTCTTTAA

Upstream 100 bases:

>100_bases
TTTCATTTGTCGATCTGGGTCAAGGTTTTTCTTGTCAAAATAACGACAATAGCGCCGTTCCCAAAATTCCTGTTCTAAAA
AAATTAAGAGTATAATAACT

Downstream 100 bases:

>100_bases
TCGTCATTCTATATGTTGATATAGACATCGATTATTCGAAGTAATAATAATGATAATAAAAGCCCCCTATTAATGGGGGC
TTATTCGAGGTAACAACATG

Product: serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MQTTTTASTGAKKAKWTYKDFTWCLSLFGTAVGAGVLFLPIKAGAGGFWPLVILALIAAPMTWFAHKSLARFVLSAKNPD
ADITDTVEEHFGKTGANLITFAYFFAIYPIVLIYGVGITNTVDSFMVNQMGMESIPRWLLSGVLITLMTCGVVFGKELML
KATSAMVYPLVFILMVLSVYLIPEWNTSMASVAPDWSAMPSVVWLAIPIIVFSFNHSPVISQFSKEQRRVYGENAVAKTD
MITGGAAMMLMSFVMFFVFSVVLSLSPEQLAQAQAQNISVLSYLANVHESPMISIMGPVVAFAAITSSYFGHFLGAHEGL
VGLTKSHTKAPLATVEKGSLIFIVVTTWIVSIVNPSILGMIETMGAPMIAAILFLMPVFAMRKVPAMAKYKTSAPVQIFT
ALCGVAAITSVIYGAL

Sequences:

>Translated_416_residues
MQTTTTASTGAKKAKWTYKDFTWCLSLFGTAVGAGVLFLPIKAGAGGFWPLVILALIAAPMTWFAHKSLARFVLSAKNPD
ADITDTVEEHFGKTGANLITFAYFFAIYPIVLIYGVGITNTVDSFMVNQMGMESIPRWLLSGVLITLMTCGVVFGKELML
KATSAMVYPLVFILMVLSVYLIPEWNTSMASVAPDWSAMPSVVWLAIPIIVFSFNHSPVISQFSKEQRRVYGENAVAKTD
MITGGAAMMLMSFVMFFVFSVVLSLSPEQLAQAQAQNISVLSYLANVHESPMISIMGPVVAFAAITSSYFGHFLGAHEGL
VGLTKSHTKAPLATVEKGSLIFIVVTTWIVSIVNPSILGMIETMGAPMIAAILFLMPVFAMRKVPAMAKYKTSAPVQIFT
ALCGVAAITSVIYGAL
>Mature_416_residues
MQTTTTASTGAKKAKWTYKDFTWCLSLFGTAVGAGVLFLPIKAGAGGFWPLVILALIAAPMTWFAHKSLARFVLSAKNPD
ADITDTVEEHFGKTGANLITFAYFFAIYPIVLIYGVGITNTVDSFMVNQMGMESIPRWLLSGVLITLMTCGVVFGKELML
KATSAMVYPLVFILMVLSVYLIPEWNTSMASVAPDWSAMPSVVWLAIPIIVFSFNHSPVISQFSKEQRRVYGENAVAKTD
MITGGAAMMLMSFVMFFVFSVVLSLSPEQLAQAQAQNISVLSYLANVHESPMISIMGPVVAFAAITSSYFGHFLGAHEGL
VGLTKSHTKAPLATVEKGSLIFIVVTTWIVSIVNPSILGMIETMGAPMIAAILFLMPVFAMRKVPAMAKYKTSAPVQIFT
ALCGVAAITSVIYGAL

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=426, Percent_Identity=50.2347417840376, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1789504, Length=441, Percent_Identity=41.7233560090703, Blast_Score=331, Evalue=6e-92,
Organism=Escherichia coli, GI1789211, Length=385, Percent_Identity=33.5064935064935, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1789961, Length=402, Percent_Identity=27.8606965174129, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI145693183, Length=414, Percent_Identity=22.463768115942, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 44873; Mature: 44873

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]