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The map label for this gene is fecD [H]

Identifier: 209693762

GI number: 209693762

Start: 179607

End: 180632

Strand: Direct

Name: fecD [H]

Synonym: VSAL_I0140

Alternate gene names: 209693762

Gene position: 179607-180632 (Clockwise)

Preceding gene: 209693761

Following gene: 209693763

Centisome position: 5.4

GC content: 46.0

Gene sequence:

>1026_bases
ATGAAAACTAATTTAGTCTCAACATGGCAGTTAGGGTCAATCGTAATACTGGCCCCAAGCAAAAGGACACTCAACGCCGT
AATCATGGCGATGATATTAATCACCCTATCTCTGGTTTTTAGTTTAATGTTAGGCAAGAATGGCATAACACCTGATGATT
TTATAACGCTATTTAAAGGTGAAGCGTCCCCATACCAAGATTGGTTGTTTTGGCAATCCAGATTACCAAGGGTTTTGTGT
GCCATCGGAGCCGGTGCCGCACTCGGTATTTCTGGGGCAGTATTTCAAACGTTAACTAAAAATCCATTAGGCAGCCCTGA
CATTATTGGTATAAACGCCGGAGCAAGTGCTGGCGCAGTATTGTGGTTATGGTTTTTGCCGAATCAACCAATAGCTATTG
GTGCCTTACTCGGTGCCGTCTCTGTTTTAACAATCATGCTGATCGCATTAGGGAAATCGTGGCAATTATCACGACAACTG
GTTCTGCTTGGGATCGCCATCAATGCCTTTGCTGTCGCGACCGTTCAACTCATTTTAACTCTGGTTCAACGAGAACAAGC
TCAGCAGCTTTTTGGTTACCTTAGTGGCAGTTTAGCCAACCGAAATTGGCAAGACGTTTCCGTCATCTTCATGACTCTTA
TTATTTTTGTTCCACTGCTTCTTCTGCTCGCTCGTCGCCTGTCTCTTCTTACCCAAGGTTATGATAGTGCAATCGTGCTA
GGAAGCCGCGTCGATACAGCACAATGGCAAGCGCTGCTTCTTGCTTCTGGACTTGCGCTTGGTGCCGTTCTGACTGTTGG
GCCAGTTGCCTTTGTTGCTTTAGTCGCTCCGCATCTTGCACGTTTTGGTCACAGCCGATTGGCGCTCTTAAGATCAGCCA
TTTATGGCAGCCTACTCCTTCTTGTTTCTGACACAATAACCCTCACCCTGCCCGGTTTATTTCGAATGCCAGTAGGCGTA
CTCACCGCATTGATTGGTGGACTCTATCTCGTGGGTTTATTAAGCCGACAAGTCACCAATAAATAA

Upstream 100 bases:

>100_bases
ATGCTCGGCGCTCCTTTTCTCTACCTCGCAGTGAGAAGAGATCAAATGAAAAAGTCGTCATCAGTAACACCTTGTAAACG
ACGTCTGAAGAGAAACTCAA

Downstream 100 bases:

>100_bases
GGATGGATGAATAAATGCAAAACAATAACGAAATAACCAAAACATTATCGGCTCATCACGTTTCATTAAGCTACAGTGAA
GGGCAAATAATCAACCGCAT

Product: iron-siderophore ABC transporter membrane permease component

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKTNLVSTWQLGSIVILAPSKRTLNAVIMAMILITLSLVFSLMLGKNGITPDDFITLFKGEASPYQDWLFWQSRLPRVLC
AIGAGAALGISGAVFQTLTKNPLGSPDIIGINAGASAGAVLWLWFLPNQPIAIGALLGAVSVLTIMLIALGKSWQLSRQL
VLLGIAINAFAVATVQLILTLVQREQAQQLFGYLSGSLANRNWQDVSVIFMTLIIFVPLLLLLARRLSLLTQGYDSAIVL
GSRVDTAQWQALLLASGLALGAVLTVGPVAFVALVAPHLARFGHSRLALLRSAIYGSLLLLVSDTITLTLPGLFRMPVGV
LTALIGGLYLVGLLSRQVTNK

Sequences:

>Translated_341_residues
MKTNLVSTWQLGSIVILAPSKRTLNAVIMAMILITLSLVFSLMLGKNGITPDDFITLFKGEASPYQDWLFWQSRLPRVLC
AIGAGAALGISGAVFQTLTKNPLGSPDIIGINAGASAGAVLWLWFLPNQPIAIGALLGAVSVLTIMLIALGKSWQLSRQL
VLLGIAINAFAVATVQLILTLVQREQAQQLFGYLSGSLANRNWQDVSVIFMTLIIFVPLLLLLARRLSLLTQGYDSAIVL
GSRVDTAQWQALLLASGLALGAVLTVGPVAFVALVAPHLARFGHSRLALLRSAIYGSLLLLVSDTITLTLPGLFRMPVGV
LTALIGGLYLVGLLSRQVTNK
>Mature_341_residues
MKTNLVSTWQLGSIVILAPSKRTLNAVIMAMILITLSLVFSLMLGKNGITPDDFITLFKGEASPYQDWLFWQSRLPRVLC
AIGAGAALGISGAVFQTLTKNPLGSPDIIGINAGASAGAVLWLWFLPNQPIAIGALLGAVSVLTIMLIALGKSWQLSRQL
VLLGIAINAFAVATVQLILTLVQREQAQQLFGYLSGSLANRNWQDVSVIFMTLIIFVPLLLLLARRLSLLTQGYDSAIVL
GSRVDTAQWQALLLASGLALGAVLTVGPVAFVALVAPHLARFGHSRLALLRSAIYGSLLLLVSDTITLTLPGLFRMPVGV
LTALIGGLYLVGLLSRQVTNK

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=314, Percent_Identity=35.3503184713376, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1786804, Length=327, Percent_Identity=33.9449541284404, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786347, Length=280, Percent_Identity=32.8571428571429, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790741, Length=298, Percent_Identity=34.8993288590604, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786805, Length=307, Percent_Identity=34.5276872964169, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788004, Length=299, Percent_Identity=29.0969899665552, Blast_Score=88, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36331; Mature: 36331

Theoretical pI: Translated: 10.97; Mature: 10.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNLVSTWQLGSIVILAPSKRTLNAVIMAMILITLSLVFSLMLGKNGITPDDFITLFKG
CCCCCCCEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEECC
EASPYQDWLFWQSRLPRVLCAIGAGAALGISGAVFQTLTKNPLGSPDIIGINAGASAGAV
CCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCE
LWLWFLPNQPIAIGALLGAVSVLTIMLIALGKSWQLSRQLVLLGIAINAFAVATVQLILT
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LVQREQAQQLFGYLSGSLANRNWQDVSVIFMTLIIFVPLLLLLARRLSLLTQGYDSAIVL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
GSRVDTAQWQALLLASGLALGAVLTVGPVAFVALVAPHLARFGHSRLALLRSAIYGSLLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
LVSDTITLTLPGLFRMPVGVLTALIGGLYLVGLLSRQVTNK
HHHCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTNLVSTWQLGSIVILAPSKRTLNAVIMAMILITLSLVFSLMLGKNGITPDDFITLFKG
CCCCCCCEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEECC
EASPYQDWLFWQSRLPRVLCAIGAGAALGISGAVFQTLTKNPLGSPDIIGINAGASAGAV
CCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCE
LWLWFLPNQPIAIGALLGAVSVLTIMLIALGKSWQLSRQLVLLGIAINAFAVATVQLILT
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LVQREQAQQLFGYLSGSLANRNWQDVSVIFMTLIIFVPLLLLLARRLSLLTQGYDSAIVL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
GSRVDTAQWQALLLASGLALGAVLTVGPVAFVALVAPHLARFGHSRLALLRSAIYGSLLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
LVSDTITLTLPGLFRMPVGVLTALIGGLYLVGLLSRQVTNK
HHHCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]