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The map label for this gene is oxaA

Identifier: 209693637

GI number: 209693637

Start: 2277

End: 3902

Strand: Reverse

Name: oxaA

Synonym: VSAL_I0003

Alternate gene names: 209693637

Gene position: 3902-2277 (Counterclockwise)

Preceding gene: 209693638

Following gene: 209693636

Centisome position: 0.12

GC content: 40.59

Gene sequence:

>1626_bases
ATGGATACCCAACGTAATATTCTGTTGCTTGCACTGGCTTTAGTTTCTTTTTTACTTTTCCAACAATGGCAAGTAGAAAC
TAATCCGCAGCAACCAGCTACAGTTAGTACCGTTCAACAGACACACAAGAACGGTGATGTTCCAACTTCGTCAACAGCAA
ACAGTGATGCACCAGTGGATTCAGCTCAGTCTGATAAACTGATCACAATTACGACTGATGTGCTTACTTTAAAAGTAGAT
ACATTAGGCGGTGACATTATTGAATCTGTTCTTAATAAATACGATGCTGAATTAGACTCTAAAGCAAAATTCGTTCTTCT
TAAGAATGATGCTGATCATAGCTATATTGCTCAAAGTGGTTTGATCGGTCCTCAAGGTATTGATTCAAATACCGGCCGTG
CACAATTTACGGCTAAAAAAACAGATTACGTTTTAGCTGATGGCCAAAACGAATTACGCATTCCTTTAACATTAGAGAAA
AACGGTATTACTTATACTAAAACTCTAATCGTTAAGCGTGACAGCTACGCAATTGATGTTGAATATACGGTGAACAACCA
ATCTTCAGCACCAGCGACAGTAGAAATGTACGCAAACTTAAAGCAAAACTTATTGGATGACGGTGGCAGTTTAACAATGC
CTACGTACCGTGGTGGTGCTTATTCAACTGAAGACACTCGCTATAAAAAATACAGCTTTGATGACATGGAAGATAAGAAC
TTATCTATCGACATGACAAATGGTCAAGGTTGGGCTGGTATGTTGCAACATTATTTTGCATCCGCTTGGATCCCTCGTAA
CGTTAATGACGCAACACTGACGACTCGTGTTGCTGGTGATTACGGTTACATTGGCGTTCGTATGCCTTCAGTAACGATTC
CTGCAGGTCAAGAAGATACGTTGACTGCTACGCTTTGGACAGGTCCAAAACTTCAACCACAAATGGCAGCGACTGCTAAA
TACTTAGATTTAAGTGTTGATTACGGTTGGTTATGGTTCATCGCTTCTCCACTTCACAAACTATTGTCTTTCATTCAAAG
CATCGTTGGAAACTGGGGTCTAGCAATTATGATCCTGACGTTCATCGTTCGTGGTGCAATGTACCCGCTAACGAAAGCAC
AATATACATCAATGGCTAAAATGCGCATGCTTCAACCTAAGTTGGCAGCAATGCGTGAACGCATTGGCGATGACCGTCAA
CGCATGAGCCAAGAAATGATGGAGCTTTATAAGAAAGAAAAAGTAAACCCACTAGGTGGTTGTTTACCTATCGTTCTTCA
AATGCCAATCTTTATTTCGCTATATTGGGCACTAATGGAATCCGTTGAACTTCGTCATGCACCATTCTTTGGTTGGATCA
CGGATTTATCAGCACAAGACCCATACTACATCCTGCCATTGTTAATGGGTGCGAGTATGTTCTTAATCCAGAAAATGAGC
CCAACAACAGTAACGGATCCAATGCAACAGAAGATCATGACATTCATTCCTGTTATGTTCACCGTGTTCTTCTTATGGTT
CCCAGCTGGCCTAGTTCTTTACTGGTTAGTATCAAACGTCGTAACGTTAATTCAGCAAACTCTGATTTATCGTGCACTTG
AGAAAAAAGGCTTACATTCTAAGTAA

Upstream 100 bases:

>100_bases
GTTGGCTAACTGGCAAACGTCTATTAAAATGTCATCCTTTGAATGATGGGGGCTATGACCCCGTCCCACCCAAGCAGCAT
AAAGACAGAGAACAATAACG

Downstream 100 bases:

>100_bases
GTTAACTTTCTAAAGAAATAAACAAAAGGCGGCCATTGGTCGCCTTTTTTGTTTTATCGGCTTACAATATGCTCAAGCAA
TAGACATTAAGAATAATCAT

Product: protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MDTQRNILLLALALVSFLLFQQWQVETNPQQPATVSTVQQTHKNGDVPTSSTANSDAPVDSAQSDKLITITTDVLTLKVD
TLGGDIIESVLNKYDAELDSKAKFVLLKNDADHSYIAQSGLIGPQGIDSNTGRAQFTAKKTDYVLADGQNELRIPLTLEK
NGITYTKTLIVKRDSYAIDVEYTVNNQSSAPATVEMYANLKQNLLDDGGSLTMPTYRGGAYSTEDTRYKKYSFDDMEDKN
LSIDMTNGQGWAGMLQHYFASAWIPRNVNDATLTTRVAGDYGYIGVRMPSVTIPAGQEDTLTATLWTGPKLQPQMAATAK
YLDLSVDYGWLWFIASPLHKLLSFIQSIVGNWGLAIMILTFIVRGAMYPLTKAQYTSMAKMRMLQPKLAAMRERIGDDRQ
RMSQEMMELYKKEKVNPLGGCLPIVLQMPIFISLYWALMESVELRHAPFFGWITDLSAQDPYYILPLLMGASMFLIQKMS
PTTVTDPMQQKIMTFIPVMFTVFFLWFPAGLVLYWLVSNVVTLIQQTLIYRALEKKGLHSK

Sequences:

>Translated_541_residues
MDTQRNILLLALALVSFLLFQQWQVETNPQQPATVSTVQQTHKNGDVPTSSTANSDAPVDSAQSDKLITITTDVLTLKVD
TLGGDIIESVLNKYDAELDSKAKFVLLKNDADHSYIAQSGLIGPQGIDSNTGRAQFTAKKTDYVLADGQNELRIPLTLEK
NGITYTKTLIVKRDSYAIDVEYTVNNQSSAPATVEMYANLKQNLLDDGGSLTMPTYRGGAYSTEDTRYKKYSFDDMEDKN
LSIDMTNGQGWAGMLQHYFASAWIPRNVNDATLTTRVAGDYGYIGVRMPSVTIPAGQEDTLTATLWTGPKLQPQMAATAK
YLDLSVDYGWLWFIASPLHKLLSFIQSIVGNWGLAIMILTFIVRGAMYPLTKAQYTSMAKMRMLQPKLAAMRERIGDDRQ
RMSQEMMELYKKEKVNPLGGCLPIVLQMPIFISLYWALMESVELRHAPFFGWITDLSAQDPYYILPLLMGASMFLIQKMS
PTTVTDPMQQKIMTFIPVMFTVFFLWFPAGLVLYWLVSNVVTLIQQTLIYRALEKKGLHSK
>Mature_541_residues
MDTQRNILLLALALVSFLLFQQWQVETNPQQPATVSTVQQTHKNGDVPTSSTANSDAPVDSAQSDKLITITTDVLTLKVD
TLGGDIIESVLNKYDAELDSKAKFVLLKNDADHSYIAQSGLIGPQGIDSNTGRAQFTAKKTDYVLADGQNELRIPLTLEK
NGITYTKTLIVKRDSYAIDVEYTVNNQSSAPATVEMYANLKQNLLDDGGSLTMPTYRGGAYSTEDTRYKKYSFDDMEDKN
LSIDMTNGQGWAGMLQHYFASAWIPRNVNDATLTTRVAGDYGYIGVRMPSVTIPAGQEDTLTATLWTGPKLQPQMAATAK
YLDLSVDYGWLWFIASPLHKLLSFIQSIVGNWGLAIMILTFIVRGAMYPLTKAQYTSMAKMRMLQPKLAAMRERIGDDRQ
RMSQEMMELYKKEKVNPLGGCLPIVLQMPIFISLYWALMESVELRHAPFFGWITDLSAQDPYYILPLLMGASMFLIQKMS
PTTVTDPMQQKIMTFIPVMFTVFFLWFPAGLVLYWLVSNVVTLIQQTLIYRALEKKGLHSK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI223718097, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1790140, Length=551, Percent_Identity=54.9909255898367, Blast_Score=595, Evalue=1e-171,
Organism=Drosophila melanogaster, GI24662345, Length=214, Percent_Identity=29.4392523364486, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21356443, Length=214, Percent_Identity=29.4392523364486, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_ALISL (B6EP40)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002261565.1
- GeneID:   6989323
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I0003
- HOGENOM:   HBG507812
- OMA:   TYRGAAF
- ProtClustDB:   PRK01318
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 60628; Mature: 60628

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c20c370)-; HASH(0x1d663e08)-; HASH(0x1d65b8e8)-; HASH(0x1d668260)-; HASH(0x1d663d84)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQRNILLLALALVSFLLFQQWQVETNPQQPATVSTVQQTHKNGDVPTSSTANSDAPVD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
SAQSDKLITITTDVLTLKVDTLGGDIIESVLNKYDAELDSKAKFVLLKNDADHSYIAQSG
CCCCCCEEEEEEEEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHCC
LIGPQGIDSNTGRAQFTAKKTDYVLADGQNELRIPLTLEKNGITYTKTLIVKRDSYAIDV
CCCCCCCCCCCCCEEEEECCCCEEEECCCCCEEEEEEEECCCCEEEEEEEEEECCEEEEE
EYTVNNQSSAPATVEMYANLKQNLLDDGGSLTMPTYRGGAYSTEDTRYKKYSFDDMEDKN
EEEECCCCCCCCHHHHHHHHHHHHHCCCCCEECCEECCCCCCCCCCCEEECCCCCCCCCC
LSIDMTNGQGWAGMLQHYFASAWIPRNVNDATLTTRVAGDYGYIGVRMPSVTIPAGQEDT
EEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECCEEECCCCCCCC
LTATLWTGPKLQPQMAATAKYLDLSVDYGWLWFIASPLHKLLSFIQSIVGNWGLAIMILT
EEEEEECCCCCCHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FIVRGAMYPLTKAQYTSMAKMRMLQPKLAAMRERIGDDRQRMSQEMMELYKKEKVNPLGG
HHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
CLPIVLQMPIFISLYWALMESVELRHAPFFGWITDLSAQDPYYILPLLMGASMFLIQKMS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHCCHHHHHCCCC
PTTVTDPMQQKIMTFIPVMFTVFFLWFPAGLVLYWLVSNVVTLIQQTLIYRALEKKGLHS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
K
H
>Mature Secondary Structure
MDTQRNILLLALALVSFLLFQQWQVETNPQQPATVSTVQQTHKNGDVPTSSTANSDAPVD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
SAQSDKLITITTDVLTLKVDTLGGDIIESVLNKYDAELDSKAKFVLLKNDADHSYIAQSG
CCCCCCEEEEEEEEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHCC
LIGPQGIDSNTGRAQFTAKKTDYVLADGQNELRIPLTLEKNGITYTKTLIVKRDSYAIDV
CCCCCCCCCCCCCEEEEECCCCEEEECCCCCEEEEEEEECCCCEEEEEEEEEECCEEEEE
EYTVNNQSSAPATVEMYANLKQNLLDDGGSLTMPTYRGGAYSTEDTRYKKYSFDDMEDKN
EEEECCCCCCCCHHHHHHHHHHHHHCCCCCEECCEECCCCCCCCCCCEEECCCCCCCCCC
LSIDMTNGQGWAGMLQHYFASAWIPRNVNDATLTTRVAGDYGYIGVRMPSVTIPAGQEDT
EEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECCEEECCCCCCCC
LTATLWTGPKLQPQMAATAKYLDLSVDYGWLWFIASPLHKLLSFIQSIVGNWGLAIMILT
EEEEEECCCCCCHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FIVRGAMYPLTKAQYTSMAKMRMLQPKLAAMRERIGDDRQRMSQEMMELYKKEKVNPLGG
HHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
CLPIVLQMPIFISLYWALMESVELRHAPFFGWITDLSAQDPYYILPLLMGASMFLIQKMS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHCCHHHHHCCCC
PTTVTDPMQQKIMTFIPVMFTVFFLWFPAGLVLYWLVSNVVTLIQQTLIYRALEKKGLHS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
K
H

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA