| Definition | Borrelia duttonii Ly, complete genome. |
|---|---|
| Accession | NC_011229 |
| Length | 931,674 |
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The map label for this gene is pbp-3 [H]
Identifier: 203284627
GI number: 203284627
Start: 783703
End: 786480
Strand: Reverse
Name: pbp-3 [H]
Synonym: BDU_735
Alternate gene names: 203284627
Gene position: 786480-783703 (Counterclockwise)
Preceding gene: 203284630
Following gene: 203284626
Centisome position: 84.42
GC content: 30.09
Gene sequence:
>2778_bases TTGAAAAGGGTTAATTTTAGCAAAAAAGCTAACATGCTAGTTTATTTTACCTATTTTATTATCAGTTTTTCAATCATTTT TTTATCAATTACCATAGTTGAAACTATAAATATTCAAAAAGATAAAAAATTTGGAAATATAAACCCTGCTATACCATCAA AACTTTTTGATACCAATGGCAAGCTCATAACACAATTTATATCTGATGAGAATAGAGAATTATTACCGTTAAGAGAAATG CCTAATAATTTAATAAATACACTCTTGATACGAGAAGATCTCAGCTTTTTTTTTCACAGAGGCTTCTCATTAATGGGAAT TTTAAGAGCTGCATTTAACATTGTTCTTGGAAGATATTTCTCAGGTGGTAGTACTCTAACACAACAATTAGCAAAACTGC TCTACACAAATCAAGCAAAAAGATCTGTTTTAAGAAAATTAAATGAAATTTGGTGGGCAATACAGCTTGAAAAAAAATTA TCAAAATATGAAATACTTGAAAAATATTTAAACAAAGTCTATTTTGGAAATGGAAATTATGGCGTAGTAGCAGCTTCAAA GTTTTTCTTCAACAAAAGTGTTAAAGATATTAACACCGCAGAAGCTGTTTTAATGATTATACAGTTACCCAATGCAAAAC TTTATTCACCATTTTATAATCCAAAATTCGCAAAAAAAATACAAAGAGCTGTATTAAATCAGGTAGTATCTCATGGCATT ATCACCCCTGAATTAGCTGAATCAGAATTTAATGAATATTGGCAAAATTATGACTGGACTCGTATGGCAGATACACCAGC TATATCTGACAAAGAAGATCATGCTCCTTATTTTTCAGAATATGTAAGACAAAGAATAACTAAATATCTACCATCAGAAG CCAATATATACAAAGATGGATACTCAATATATACAACACTTGATCTTGAAGCACAAAAACATGCAAATGAAATTACACAA GAAATGATTACAAAAGCAAGAAAAATGTATAATTCTACAAAATCATCTGAAACATTAGTAATAAATTCAGAAATAGTACC AATAATTGATACAATGGCCGATTTATTTGGCATAAGAAATACTAGAATAAATGGTAGACAATATACAAAATTAAAAACAA GAAAATTTTATGAGGATAATATTGATCTTCTTGCAAGCTTTGCTGCAATTTTAGGTATTGATAAAATAGACAAAGCAACA AGAGCTTACACAATAAACAATAAAACAAACCCAAACTTACTTGTGCAACCAGAAGGTGCATTAATATCACTAGACACCAC AACAGGAGCCATCAAAGCAATGGTTGGAGGAAGTGGTTATAGAAAGGGAAGCGAATTTAATAGAGCAACTCAAGCAAAAA TTCAACCTGGAAGCGCATTTAAAGTTTTATATTTCTCAGCGGCTATTGAATTAAAAAAAATAACAGCTGCAACAATGCTC TCAGATTCTCCAGTAGCCTTTTTTAATCAGGAAGGAGAGGTGTATGCCCCTGAAAATTATGGAGGGAAATGGCGAGGAAA TGTCTTAACACGCAAAGCACTAGCTTTATCTCTAAATATTCCCGCCCTTAGAATACTTGATAAATTGGGTTTTGACAATG CAATTAAATATTCGGCTAAATTACTAGGAATCAAAGATCAAAATGAAATAAACAAAATATTCCCTAAAGTATATCCCCTT GCACTTGGAGTCACATCAACATCTCCAATACAAATGGCAAGAGCATTTGCTATTTTAGGAAATAATGGAAAAGAAGTAGA ACCATATGGAATTAAATATATAGAAGATCGAAATGGAAAAGTAATAGCAAATGTAGAATCTGAAATACTAACATCAATCA AAAATAAAGGTGCTAATGCACAAATAGTATCTCCTCAAACTGCTTACATTATGACAGATATGATGAAATCAACAATTCAA TATGGTACTCTATCAAATCAAAGATATACAAATCTTAAAAATTTTAAATCTGATATTGTAGGTAAATCAGGAACAACCCA AAATTGGGCCGACGGATGGACAATAGGATATTCACCTTATATAACAACAGCTATATGGGTTGGTTTTGACAAAAAAGGAT ATTCATTGGGAACTGCAGGAACAGGAACAGCACTAGCTGGCCCTACTTGGGGTAAGTTTATGGCAGAATATCATAAAAAC TTACCCCAAAAGGTATTTATACGACCCAAAGGAATAATTAATGTACAAGTCCAATCAGAAACAGGTCTATTACCAGAAGG TGTACCTAATGAAACAATAATAAATGAAATATTCATTACAGGAAGCCAACCATTTGAAAAATCAAAATACTATGAAAACA AATCTGAATTTTTAAATAAAATGGAATTCAATATTTATGGTATCGACAACATTAATGACAATGATGAACTAAACTTCGAT ACTACCGAATTTGAATATCTCACAAACGATTTTCATCAATACAATAAAACAGAAAATGAAAAAATTCATGAAAATAATAC TAATACAATTAATAATGATAAATTTAATGATAATATTAATATGGATATACAAAATGATGATTTTGAATACGACAATCAAG AGGAAAACATGCAACATAGTATCCAAGATGCTAATAAAACAGAGAACGAAACCAACAACACAATAACAGATGACAATAAC AATGTAGATGATAGTATTAAAACTACAGATCAACCAAATAATACAGAACCTAAAAAAAATCCTCTTATCAGTGATGAAAA ACAAGATAATGAAATTGAACATAAAGATGTCAATGGAGAAAATATACAATTGGATTAA
Upstream 100 bases:
>100_bases GCATTATAACAATATTTTTATACTAATAACAACTTGCAAAATGTTAAGTTTATCATATTTTATAGTATAATTACGTTGAA AGACGTTAGAAGGATACAAT
Downstream 100 bases:
>100_bases TAAAATATGTTAATAGATTTAGAACAAATAAAAATCAAAAAACGAATCAGAAAAAATATAGGAGATACAACAACTCTTAA AGAAAGCATTAAAAAACATG
Product: penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 925; Mature: 925
Protein sequence:
>925_residues MKRVNFSKKANMLVYFTYFIISFSIIFLSITIVETINIQKDKKFGNINPAIPSKLFDTNGKLITQFISDENRELLPLREM PNNLINTLLIREDLSFFFHRGFSLMGILRAAFNIVLGRYFSGGSTLTQQLAKLLYTNQAKRSVLRKLNEIWWAIQLEKKL SKYEILEKYLNKVYFGNGNYGVVAASKFFFNKSVKDINTAEAVLMIIQLPNAKLYSPFYNPKFAKKIQRAVLNQVVSHGI ITPELAESEFNEYWQNYDWTRMADTPAISDKEDHAPYFSEYVRQRITKYLPSEANIYKDGYSIYTTLDLEAQKHANEITQ EMITKARKMYNSTKSSETLVINSEIVPIIDTMADLFGIRNTRINGRQYTKLKTRKFYEDNIDLLASFAAILGIDKIDKAT RAYTINNKTNPNLLVQPEGALISLDTTTGAIKAMVGGSGYRKGSEFNRATQAKIQPGSAFKVLYFSAAIELKKITAATML SDSPVAFFNQEGEVYAPENYGGKWRGNVLTRKALALSLNIPALRILDKLGFDNAIKYSAKLLGIKDQNEINKIFPKVYPL ALGVTSTSPIQMARAFAILGNNGKEVEPYGIKYIEDRNGKVIANVESEILTSIKNKGANAQIVSPQTAYIMTDMMKSTIQ YGTLSNQRYTNLKNFKSDIVGKSGTTQNWADGWTIGYSPYITTAIWVGFDKKGYSLGTAGTGTALAGPTWGKFMAEYHKN LPQKVFIRPKGIINVQVQSETGLLPEGVPNETIINEIFITGSQPFEKSKYYENKSEFLNKMEFNIYGIDNINDNDELNFD TTEFEYLTNDFHQYNKTENEKIHENNTNTINNDKFNDNINMDIQNDDFEYDNQEENMQHSIQDANKTENETNNTITDDNN NVDDSIKTTDQPNNTEPKKNPLISDEKQDNEIEHKDVNGENIQLD
Sequences:
>Translated_925_residues MKRVNFSKKANMLVYFTYFIISFSIIFLSITIVETINIQKDKKFGNINPAIPSKLFDTNGKLITQFISDENRELLPLREM PNNLINTLLIREDLSFFFHRGFSLMGILRAAFNIVLGRYFSGGSTLTQQLAKLLYTNQAKRSVLRKLNEIWWAIQLEKKL SKYEILEKYLNKVYFGNGNYGVVAASKFFFNKSVKDINTAEAVLMIIQLPNAKLYSPFYNPKFAKKIQRAVLNQVVSHGI ITPELAESEFNEYWQNYDWTRMADTPAISDKEDHAPYFSEYVRQRITKYLPSEANIYKDGYSIYTTLDLEAQKHANEITQ EMITKARKMYNSTKSSETLVINSEIVPIIDTMADLFGIRNTRINGRQYTKLKTRKFYEDNIDLLASFAAILGIDKIDKAT RAYTINNKTNPNLLVQPEGALISLDTTTGAIKAMVGGSGYRKGSEFNRATQAKIQPGSAFKVLYFSAAIELKKITAATML SDSPVAFFNQEGEVYAPENYGGKWRGNVLTRKALALSLNIPALRILDKLGFDNAIKYSAKLLGIKDQNEINKIFPKVYPL ALGVTSTSPIQMARAFAILGNNGKEVEPYGIKYIEDRNGKVIANVESEILTSIKNKGANAQIVSPQTAYIMTDMMKSTIQ YGTLSNQRYTNLKNFKSDIVGKSGTTQNWADGWTIGYSPYITTAIWVGFDKKGYSLGTAGTGTALAGPTWGKFMAEYHKN LPQKVFIRPKGIINVQVQSETGLLPEGVPNETIINEIFITGSQPFEKSKYYENKSEFLNKMEFNIYGIDNINDNDELNFD TTEFEYLTNDFHQYNKTENEKIHENNTNTINNDKFNDNINMDIQNDDFEYDNQEENMQHSIQDANKTENETNNTITDDNN NVDDSIKTTDQPNNTEPKKNPLISDEKQDNEIEHKDVNGENIQLD >Mature_925_residues MKRVNFSKKANMLVYFTYFIISFSIIFLSITIVETINIQKDKKFGNINPAIPSKLFDTNGKLITQFISDENRELLPLREM PNNLINTLLIREDLSFFFHRGFSLMGILRAAFNIVLGRYFSGGSTLTQQLAKLLYTNQAKRSVLRKLNEIWWAIQLEKKL SKYEILEKYLNKVYFGNGNYGVVAASKFFFNKSVKDINTAEAVLMIIQLPNAKLYSPFYNPKFAKKIQRAVLNQVVSHGI ITPELAESEFNEYWQNYDWTRMADTPAISDKEDHAPYFSEYVRQRITKYLPSEANIYKDGYSIYTTLDLEAQKHANEITQ EMITKARKMYNSTKSSETLVINSEIVPIIDTMADLFGIRNTRINGRQYTKLKTRKFYEDNIDLLASFAAILGIDKIDKAT RAYTINNKTNPNLLVQPEGALISLDTTTGAIKAMVGGSGYRKGSEFNRATQAKIQPGSAFKVLYFSAAIELKKITAATML SDSPVAFFNQEGEVYAPENYGGKWRGNVLTRKALALSLNIPALRILDKLGFDNAIKYSAKLLGIKDQNEINKIFPKVYPL ALGVTSTSPIQMARAFAILGNNGKEVEPYGIKYIEDRNGKVIANVESEILTSIKNKGANAQIVSPQTAYIMTDMMKSTIQ YGTLSNQRYTNLKNFKSDIVGKSGTTQNWADGWTIGYSPYITTAIWVGFDKKGYSLGTAGTGTALAGPTWGKFMAEYHKN LPQKVFIRPKGIINVQVQSETGLLPEGVPNETIINEIFITGSQPFEKSKYYENKSEFLNKMEFNIYGIDNINDNDELNFD TTEFEYLTNDFHQYNKTENEKIHENNTNTINNDKFNDNINMDIQNDDFEYDNQEENMQHSIQDANKTENETNNTITDDNN NVDDSIKTTDQPNNTEPKKNPLISDEKQDNEIEHKDVNGENIQLD
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=604, Percent_Identity=29.635761589404, Blast_Score=214, Evalue=2e-56, Organism=Escherichia coli, GI1786343, Length=321, Percent_Identity=30.5295950155763, Blast_Score=114, Evalue=3e-26, Organism=Escherichia coli, GI1788867, Length=239, Percent_Identity=31.7991631799163, Blast_Score=89, Evalue=1e-18, Organism=Escherichia coli, GI1789601, Length=149, Percent_Identity=33.5570469798658, Blast_Score=66, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 105021; Mature: 105021
Theoretical pI: Translated: 7.05; Mature: 7.05
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRVNFSKKANMLVYFTYFIISFSIIFLSITIVETINIQKDKKFGNINPAIPSKLFDTNG CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHCCCC KLITQFISDENRELLPLREMPNNLINTLLIREDLSFFFHRGFSLMGILRAAFNIVLGRYF HHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC SGGSTLTQQLAKLLYTNQAKRSVLRKLNEIWWAIQLEKKLSKYEILEKYLNKVYFGNGNY CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHEEECCCCE GVVAASKFFFNKSVKDINTAEAVLMIIQLPNAKLYSPFYNPKFAKKIQRAVLNQVVSHGI EEEEEHHHHHCCCCCCCCHHHEEEEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHCCC ITPELAESEFNEYWQNYDWTRMADTPAISDKEDHAPYFSEYVRQRITKYLPSEANIYKDG CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECC YSIYTTLDLEAQKHANEITQEMITKARKMYNSTKSSETLVINSEIVPIIDTMADLFGIRN EEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCC TRINGRQYTKLKTRKFYEDNIDLLASFAAILGIDKIDKATRAYTINNKTNPNLLVQPEGA CCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCC LISLDTTTGAIKAMVGGSGYRKGSEFNRATQAKIQPGSAFKVLYFSAAIELKKITAATML EEEEECCCCHHHHEECCCCCCCCCHHCCCHHCEECCCCCEEEEEEHHHHHHHHHHHHHHC SDSPVAFFNQEGEVYAPENYGGKWRGNVLTRKALALSLNIPALRILDKLGFDNAIKYSAK CCCCEEEECCCCCEECCCCCCCCCCCCHHEEEEEEEEECCCHHHHHHHHCCCCHHEEHEE LLGIKDQNEINKIFPKVYPLALGVTSTSPIQMARAFAILGNNGKEVEPYGIKYIEDRNGK EECCCCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHEEECCCCCCCCCCCCEEEECCCCE VIANVESEILTSIKNKGANAQIVSPQTAYIMTDMMKSTIQYGTLSNQRYTNLKNFKSDIV EEEECHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC GKSGTTQNWADGWTIGYSPYITTAIWVGFDKKGYSLGTAGTGTALAGPTWGKFMAEYHKN CCCCCCCCCCCCEEECCCHHEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC LPQKVFIRPKGIINVQVQSETGLLPEGVPNETIINEIFITGSQPFEKSKYYENKSEFLNK CCCEEEECCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHCCHHHHHHH MEFNIYGIDNINDNDELNFDTTEFEYLTNDFHQYNKTENEKIHENNTNTINNDKFNDNIN HEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEE MDIQNDDFEYDNQEENMQHSIQDANKTENETNNTITDDNNNVDDSIKTTDQPNNTEPKKN EEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PLISDEKQDNEIEHKDVNGENIQLD CCCCCCCCCCCCCCCCCCCCEEEEC >Mature Secondary Structure MKRVNFSKKANMLVYFTYFIISFSIIFLSITIVETINIQKDKKFGNINPAIPSKLFDTNG CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHCCCC KLITQFISDENRELLPLREMPNNLINTLLIREDLSFFFHRGFSLMGILRAAFNIVLGRYF HHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC SGGSTLTQQLAKLLYTNQAKRSVLRKLNEIWWAIQLEKKLSKYEILEKYLNKVYFGNGNY CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHEEECCCCE GVVAASKFFFNKSVKDINTAEAVLMIIQLPNAKLYSPFYNPKFAKKIQRAVLNQVVSHGI EEEEEHHHHHCCCCCCCCHHHEEEEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHCCC ITPELAESEFNEYWQNYDWTRMADTPAISDKEDHAPYFSEYVRQRITKYLPSEANIYKDG CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECC YSIYTTLDLEAQKHANEITQEMITKARKMYNSTKSSETLVINSEIVPIIDTMADLFGIRN EEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCC TRINGRQYTKLKTRKFYEDNIDLLASFAAILGIDKIDKATRAYTINNKTNPNLLVQPEGA CCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCC LISLDTTTGAIKAMVGGSGYRKGSEFNRATQAKIQPGSAFKVLYFSAAIELKKITAATML EEEEECCCCHHHHEECCCCCCCCCHHCCCHHCEECCCCCEEEEEEHHHHHHHHHHHHHHC SDSPVAFFNQEGEVYAPENYGGKWRGNVLTRKALALSLNIPALRILDKLGFDNAIKYSAK CCCCEEEECCCCCEECCCCCCCCCCCCHHEEEEEEEEECCCHHHHHHHHCCCCHHEEHEE LLGIKDQNEINKIFPKVYPLALGVTSTSPIQMARAFAILGNNGKEVEPYGIKYIEDRNGK EECCCCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHEEECCCCCCCCCCCCEEEECCCCE VIANVESEILTSIKNKGANAQIVSPQTAYIMTDMMKSTIQYGTLSNQRYTNLKNFKSDIV EEEECHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC GKSGTTQNWADGWTIGYSPYITTAIWVGFDKKGYSLGTAGTGTALAGPTWGKFMAEYHKN CCCCCCCCCCCCEEECCCHHEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC LPQKVFIRPKGIINVQVQSETGLLPEGVPNETIINEIFITGSQPFEKSKYYENKSEFLNK CCCEEEECCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHCCHHHHHHH MEFNIYGIDNINDNDELNFDTTEFEYLTNDFHQYNKTENEKIHENNTNTINNDKFNDNIN HEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEE MDIQNDDFEYDNQEENMQHSIQDANKTENETNNTITDDNNNVDDSIKTTDQPNNTEPKKN EEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PLISDEKQDNEIEHKDVNGENIQLD CCCCCCCCCCCCCCCCCCCCEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA