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The map label for this gene is nox [C]

Identifier: 203284623

GI number: 203284623

Start: 778914

End: 780245

Strand: Reverse

Name: nox [C]

Synonym: BDU_731

Alternate gene names: 203284623

Gene position: 780245-778914 (Counterclockwise)

Preceding gene: 203284624

Following gene: 203284618

Centisome position: 83.75

GC content: 30.11

Gene sequence:

>1332_bases
ATGAAAATAATAATTATTGGAGGAACTGCAGCAGGAACAAGCGCTGCAGCAAAAGCAAAACGAATAAACAAAGAATTAAA
TATAGTTATTTACGAGAAAACAAATACCACATCCTTTGGTGCTTGTGGACTACCTTATTTCATTGGAAAATTTTTTGACG
AACCAAATAATATGATAGCCCGGACACCTGAACAATTTAAACAGAATGGAATATCAGTATTTCCTAAACACGAAGTCACT
AAAGTAGATATCAAAAATAATATTCTTCAAGTAAAAAATCTTCAAACACAAGAAATATTCAATGATACCTATGATAAATT
AATGATTGCAACTGGGGGAACCCCTATAATTCCACCAATTAACAATATTAAACTAAAAAATTTTTATACTTTAAGAAATA
TGAAAGATGGTAAGGAAATCAGAGAACTCTTAAACAAACAAGAAATAAAAAACATCATAATAATTGGGGCTGGATATATT
GGAATTGAAATGGTAGAAGCTACTAAAGCACGAGAAAAAAATGTAAGAATTATTCAATTGGATAAACGAATATTAACAGA
ATCATTTGACAAAGAAATCACAAATATAATGGAAGAAGAGCTTATAAAAAACAACGTTTTACTTCATACAAATGAATTCG
TAACAAGTTTAATAGGAAAAGACAAAGTTGAAGGAATTATTACAAACAAATCTGAATACAAAGCAGATCTTGTAATACTC
TCTACAGGCATAAAACCTGCAACTGAATTTTTAGAAGGTCAACTTGATACATTAAAAAACGGTGCAATAATTGTAAATGA
ATACGGTGAAACCAGTGCAAAAAACATTTTTGCTGCAGGAGATTGTGCCACAATATATAACATTATAAGCAATCAAAATG
ATTATATTCCTCTTGCAACAACAGCTAATAAATTGGGAAAAATAATTGGTGAAAACCTAGCAGGAAAACGAGTATCTTTT
AAAGGCACATTGGGATCTGCATCTATTAAAGTTTTATCACTAGAAGCAGCTAGATCTGGTCTTACTGAAGAGATGGCATT
AAAACTTGGAATCCAATATAAAACGGTATTTATCAAAGATAAAAACCATACAAACTATTATCCCAATCAAGAAGATTTAT
ATATTAAGCTAATCTATAATCAAGATACAAAAGAAATTCTTGGTGCACAAATAATTGGAAAAAATGGAGCTGCACTAAGA
ATGCACGCATTATCCCTTGCTATTTATTCAAAACTTAAAATAAATGAACTTGGAATGATGGATTTTGCATATTCTCCACC
ATTCTCCAAAACTTGGGATGCATTAAATATTGCTGGTAATGCAGCAAAATAA

Upstream 100 bases:

>100_bases
TAGTGACTCAATGGTTGCAGGGGTCATAACAGCCAAAAATCTTAATCAATTAGATAAAAACATTTACAATAATCAAAATA
CTAAATAAAAGGTAATTCTT

Downstream 100 bases:

>100_bases
ATAAAAAAACTTAAATTACTTTTTGGTTAATTTTTCATACTAAATGGCTGACCAGTACTTGCAAGAACATCCCTCCAGAA
AGAACCATTCACATTAACTT

Product: coenzyme A disulfide reductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKIIIIGGTAAGTSAAAKAKRINKELNIVIYEKTNTTSFGACGLPYFIGKFFDEPNNMIARTPEQFKQNGISVFPKHEVT
KVDIKNNILQVKNLQTQEIFNDTYDKLMIATGGTPIIPPINNIKLKNFYTLRNMKDGKEIRELLNKQEIKNIIIIGAGYI
GIEMVEATKAREKNVRIIQLDKRILTESFDKEITNIMEEELIKNNVLLHTNEFVTSLIGKDKVEGIITNKSEYKADLVIL
STGIKPATEFLEGQLDTLKNGAIIVNEYGETSAKNIFAAGDCATIYNIISNQNDYIPLATTANKLGKIIGENLAGKRVSF
KGTLGSASIKVLSLEAARSGLTEEMALKLGIQYKTVFIKDKNHTNYYPNQEDLYIKLIYNQDTKEILGAQIIGKNGAALR
MHALSLAIYSKLKINELGMMDFAYSPPFSKTWDALNIAGNAAK

Sequences:

>Translated_443_residues
MKIIIIGGTAAGTSAAAKAKRINKELNIVIYEKTNTTSFGACGLPYFIGKFFDEPNNMIARTPEQFKQNGISVFPKHEVT
KVDIKNNILQVKNLQTQEIFNDTYDKLMIATGGTPIIPPINNIKLKNFYTLRNMKDGKEIRELLNKQEIKNIIIIGAGYI
GIEMVEATKAREKNVRIIQLDKRILTESFDKEITNIMEEELIKNNVLLHTNEFVTSLIGKDKVEGIITNKSEYKADLVIL
STGIKPATEFLEGQLDTLKNGAIIVNEYGETSAKNIFAAGDCATIYNIISNQNDYIPLATTANKLGKIIGENLAGKRVSF
KGTLGSASIKVLSLEAARSGLTEEMALKLGIQYKTVFIKDKNHTNYYPNQEDLYIKLIYNQDTKEILGAQIIGKNGAALR
MHALSLAIYSKLKINELGMMDFAYSPPFSKTWDALNIAGNAAK
>Mature_443_residues
MKIIIIGGTAAGTSAAAKAKRINKELNIVIYEKTNTTSFGACGLPYFIGKFFDEPNNMIARTPEQFKQNGISVFPKHEVT
KVDIKNNILQVKNLQTQEIFNDTYDKLMIATGGTPIIPPINNIKLKNFYTLRNMKDGKEIRELLNKQEIKNIIIIGAGYI
GIEMVEATKAREKNVRIIQLDKRILTESFDKEITNIMEEELIKNNVLLHTNEFVTSLIGKDKVEGIITNKSEYKADLVIL
STGIKPATEFLEGQLDTLKNGAIIVNEYGETSAKNIFAAGDCATIYNIISNQNDYIPLATTANKLGKIIGENLAGKRVSF
KGTLGSASIKVLSLEAARSGLTEEMALKLGIQYKTVFIKDKNHTNYYPNQEDLYIKLIYNQDTKEILGAQIIGKNGAALR
MHALSLAIYSKLKINELGMMDFAYSPPFSKTWDALNIAGNAAK

Specific function: Nitrate assimilation (denitrification); second step. [C]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=325, Percent_Identity=25.2307692307692, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI65787454, Length=325, Percent_Identity=25.2307692307692, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226437568, Length=325, Percent_Identity=25.2307692307692, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI22202629, Length=278, Percent_Identity=26.6187050359712, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4757732, Length=278, Percent_Identity=26.6187050359712, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789065, Length=351, Percent_Identity=22.7920227920228, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789765, Length=333, Percent_Identity=23.7237237237237, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788892, Length=182, Percent_Identity=30.2197802197802, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786307, Length=348, Percent_Identity=24.4252873563218, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17559934, Length=259, Percent_Identity=27.7992277992278, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24585130, Length=329, Percent_Identity=24.0121580547112, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24639257, Length=230, Percent_Identity=23.9130434782609, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281359715, Length=230, Percent_Identity=23.9130434782609, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281359713, Length=230, Percent_Identity=23.9130434782609, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639250, Length=230, Percent_Identity=23.9130434782609, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI18543267, Length=230, Percent_Identity=23.9130434782609, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639252, Length=230, Percent_Identity=23.9130434782609, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 49145; Mature: 49145

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIIIGGTAAGTSAAAKAKRINKELNIVIYEKTNTTSFGACGLPYFIGKFFDEPNNMIA
CEEEEEECCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEE
RTPEQFKQNGISVFPKHEVTKVDIKNNILQVKNLQTQEIFNDTYDKLMIATGGTPIIPPI
CCCHHHHHCCCEECCCCCEEEEECCCCEEEECCCCHHHHHHCCCCEEEEEECCCCCCCCC
NNIKLKNFYTLRNMKDGKEIRELLNKQEIKNIIIIGAGYIGIEMVEATKAREKNVRIIQL
CCEEEEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCEEEEEHHHHHHHCCCEEEEE
DKRILTESFDKEITNIMEEELIKNNVLLHTNEFVTSLIGKDKVEGIITNKSEYKADLVIL
CHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCHHCCEEEECCCCCEEEEEEE
STGIKPATEFLEGQLDTLKNGAIIVNEYGETSAKNIFAAGDCATIYNIISNQNDYIPLAT
ECCCCHHHHHHCCCHHHCCCCEEEEECCCCCCCCCEEECCCHHHHHHHHCCCCCEEEEEE
TANKLGKIIGENLAGKRVSFKGTLGSASIKVLSLEAARSGLTEEMALKLGIQYKTVFIKD
CHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEHHHHCCCCHHHHHHCCCEEEEEEEEC
KNHTNYYPNQEDLYIKLIYNQDTKEILGAQIIGKNGAALRMHALSLAIYSKLKINELGMM
CCCCCCCCCCCCEEEEEEECCCHHHHHCEEEECCCCCEEEHHHHHHHHHHHEEECCCCCE
DFAYSPPFSKTWDALNIAGNAAK
EEECCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure
MKIIIIGGTAAGTSAAAKAKRINKELNIVIYEKTNTTSFGACGLPYFIGKFFDEPNNMIA
CEEEEEECCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEE
RTPEQFKQNGISVFPKHEVTKVDIKNNILQVKNLQTQEIFNDTYDKLMIATGGTPIIPPI
CCCHHHHHCCCEECCCCCEEEEECCCCEEEECCCCHHHHHHCCCCEEEEEECCCCCCCCC
NNIKLKNFYTLRNMKDGKEIRELLNKQEIKNIIIIGAGYIGIEMVEATKAREKNVRIIQL
CCEEEEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCEEEEEHHHHHHHCCCEEEEE
DKRILTESFDKEITNIMEEELIKNNVLLHTNEFVTSLIGKDKVEGIITNKSEYKADLVIL
CHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCHHCCEEEECCCCCEEEEEEE
STGIKPATEFLEGQLDTLKNGAIIVNEYGETSAKNIFAAGDCATIYNIISNQNDYIPLAT
ECCCCHHHHHHCCCHHHCCCCEEEEECCCCCCCCCEEECCCHHHHHHHHCCCCCEEEEEE
TANKLGKIIGENLAGKRVSFKGTLGSASIKVLSLEAARSGLTEEMALKLGIQYKTVFIKD
CHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEHHHHCCCCHHHHHHCCCEEEEEEEEC
KNHTNYYPNQEDLYIKLIYNQDTKEILGAQIIGKNGAALRMHALSLAIYSKLKINELGMM
CCCCCCCCCCCCEEEEEEECCCHHHHHCEEEECCCCCEEEHHHHHHHHHHHEEECCCCCE
DFAYSPPFSKTWDALNIAGNAAK
EEECCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA