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The map label for this gene is htpG [H]

Identifier: 203284466

GI number: 203284466

Start: 588021

End: 589868

Strand: Reverse

Name: htpG [H]

Synonym: BDU_562

Alternate gene names: 203284466

Gene position: 589868-588021 (Counterclockwise)

Preceding gene: 203284468

Following gene: 203284459

Centisome position: 63.31

GC content: 26.35

Gene sequence:

>1848_bases
ATGAAAAAACAATTTGATACAGAAGTCAATGATTTACTTTATTTAATCATACATTCTCTTTACTCACATAAAGAAATATT
TTTAAGAGAATTAATATCAAATGCTTCTGATGCCATTGATAAACTTAAATTTTTAAACATCACAGATGAAAAATTTAAAG
ACATAAAATTAGATCCTCGAATAGATATAAATTTTGATGAAAAATCCATCACAATAAAAGATAATGGAATTGGAATGAAT
AGAGAGGATTTAATTAGTCACCTCGGAACAATTGCAAAATCAGGCACTAAAGAATTTATTAACAACTTAAAAAAAGATGA
AAAAAAAGCTTCAAGCCTAATTGGACAATTTGGTGTTGGTTTTTACAGTGCTTTTATTGTAGCAGACAAAGTTGAAGTTA
TAACAAAAAAAGCTCTAGATAATATTGCATATATTTGGTCTAGTGATGGAAAAACAGGATATGAAATCAATGAAACAAAT
AAAGATGAGAATGGAACTGAAATAATACTTCACCTTAATAAAGAGGGAACCGAATATGCTAACAAATGGAAAATTCAAGA
AATTATAAAAAAATACTCAAATCATATAAGCTATCCTATTTTTATTAAATATAGAGAACCTATAATGAAGGATGGCAAAC
AAGAAGGATTTGAAGAGAAAGAAGATAAATTAAATGATACAACAGCTATTTGGACAAAAAATAAAAATGAAATCTCTAAT
GAAGAATATAATGAATTTTATAAAAATTTAGCTTTTGATTATGAAAATCCATTAATTCATATTCATACAAAAGCCGAGGG
AAGTATTGAATACACAAATCTTTTCTACGTTCCAAGTAAAGCTTCCTATGACCTATATTATCCAAATACTAAACCTGGGG
TAAAATTATTTATAAATAGAATTTTTATTTCAGATTCTGCTGACAGCTTACTTCCAAATTACCTAAGATTTATAAAAGGA
ATAATAGATTGCCAAGATTTACCCCTAAATGTAAGTAGAGAAATTTTACAAAAAAATAAAACATTAGCCAAAATAAAGGC
ATCTTCTGTAAAAAAAATACTTAGCGAACTTGAAAAATTAAGTGAAAACGACCCCACTAAATTCAATGAATTTTCTAAAG
AATTTGGAAGATGCTTAAAAGAAGGGGTTTATTCCGATTTTGATAATAGAAATAAGCTAATATCTCTAATTAGATTCAAA
TCTTCTAATGTAAATGGATTTGTATCACTAAAAGAATATAAAGATAGAATGCCTGCAGAACAAAAAAGCATATATTACAT
CACTGGAGGCAAAGAAAATATTCTTAAAATCAACCCTATTGTAAATGCTTATAAAGATAGAGGATATGAAACTCTCATTA
TGGATGATGAGATTGACGAAGCTATTTTAAATTTCATAACAGAATATGAGGGCATTAAATTAAAAGCAATAAATAAAAAT
GAAACAAGTGATGAATTAAAAGATGAAAATTTCAAAAAAATAGAAGAAGAATTTCAAGACATACTGTCTAAAATAAAAGA
AATATTAAAAGATCATGTTAAAGATGTTTCATTATCAGCAACCCTCGTACAAGAACCATCAGCAATAATAATTGACAGCA
CTGATCCTACTTATCAAATGCAAAAAATCATGCTATCAATGGGACAAGAAGTTAAAGAAACAAAACCCATTCTTGAACTT
AATCCAAACAACAAAATTATTCAAAATTTAAAAAATTTAGATGATACAACCTTAGAAAAAATAAGCATCATTCTTCTTGA
AGAAGCAATAATAACTTCAGGACTGCCAAGCAAAAACCCAAATCAATTTATAAACATAATAAATGAAATGTTAGAAAAAA
ATATATAA

Upstream 100 bases:

>100_bases
TCGTATTTTTTTCATAGAAAAATTATTTATTCATTATTTTTAGATTATGTTATATTATAAAAAAAGTAAAGATTAAACGA
ATACAAGATAGGAGAATTCT

Downstream 100 bases:

>100_bases
ATAAAAGTAAGTTCGCATACTCATGAGTATGCGAACTTACTTTTTAACTCTAAGAACTATATCTTTACCCGCTTCAACAG
GACTAGCTTGTAATATTTTA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MKKQFDTEVNDLLYLIIHSLYSHKEIFLRELISNASDAIDKLKFLNITDEKFKDIKLDPRIDINFDEKSITIKDNGIGMN
REDLISHLGTIAKSGTKEFINNLKKDEKKASSLIGQFGVGFYSAFIVADKVEVITKKALDNIAYIWSSDGKTGYEINETN
KDENGTEIILHLNKEGTEYANKWKIQEIIKKYSNHISYPIFIKYREPIMKDGKQEGFEEKEDKLNDTTAIWTKNKNEISN
EEYNEFYKNLAFDYENPLIHIHTKAEGSIEYTNLFYVPSKASYDLYYPNTKPGVKLFINRIFISDSADSLLPNYLRFIKG
IIDCQDLPLNVSREILQKNKTLAKIKASSVKKILSELEKLSENDPTKFNEFSKEFGRCLKEGVYSDFDNRNKLISLIRFK
SSNVNGFVSLKEYKDRMPAEQKSIYYITGGKENILKINPIVNAYKDRGYETLIMDDEIDEAILNFITEYEGIKLKAINKN
ETSDELKDENFKKIEEEFQDILSKIKEILKDHVKDVSLSATLVQEPSAIIIDSTDPTYQMQKIMLSMGQEVKETKPILEL
NPNNKIIQNLKNLDDTTLEKISIILLEEAIITSGLPSKNPNQFINIINEMLEKNI

Sequences:

>Translated_615_residues
MKKQFDTEVNDLLYLIIHSLYSHKEIFLRELISNASDAIDKLKFLNITDEKFKDIKLDPRIDINFDEKSITIKDNGIGMN
REDLISHLGTIAKSGTKEFINNLKKDEKKASSLIGQFGVGFYSAFIVADKVEVITKKALDNIAYIWSSDGKTGYEINETN
KDENGTEIILHLNKEGTEYANKWKIQEIIKKYSNHISYPIFIKYREPIMKDGKQEGFEEKEDKLNDTTAIWTKNKNEISN
EEYNEFYKNLAFDYENPLIHIHTKAEGSIEYTNLFYVPSKASYDLYYPNTKPGVKLFINRIFISDSADSLLPNYLRFIKG
IIDCQDLPLNVSREILQKNKTLAKIKASSVKKILSELEKLSENDPTKFNEFSKEFGRCLKEGVYSDFDNRNKLISLIRFK
SSNVNGFVSLKEYKDRMPAEQKSIYYITGGKENILKINPIVNAYKDRGYETLIMDDEIDEAILNFITEYEGIKLKAINKN
ETSDELKDENFKKIEEEFQDILSKIKEILKDHVKDVSLSATLVQEPSAIIIDSTDPTYQMQKIMLSMGQEVKETKPILEL
NPNNKIIQNLKNLDDTTLEKISIILLEEAIITSGLPSKNPNQFINIINEMLEKNI
>Mature_615_residues
MKKQFDTEVNDLLYLIIHSLYSHKEIFLRELISNASDAIDKLKFLNITDEKFKDIKLDPRIDINFDEKSITIKDNGIGMN
REDLISHLGTIAKSGTKEFINNLKKDEKKASSLIGQFGVGFYSAFIVADKVEVITKKALDNIAYIWSSDGKTGYEINETN
KDENGTEIILHLNKEGTEYANKWKIQEIIKKYSNHISYPIFIKYREPIMKDGKQEGFEEKEDKLNDTTAIWTKNKNEISN
EEYNEFYKNLAFDYENPLIHIHTKAEGSIEYTNLFYVPSKASYDLYYPNTKPGVKLFINRIFISDSADSLLPNYLRFIKG
IIDCQDLPLNVSREILQKNKTLAKIKASSVKKILSELEKLSENDPTKFNEFSKEFGRCLKEGVYSDFDNRNKLISLIRFK
SSNVNGFVSLKEYKDRMPAEQKSIYYITGGKENILKINPIVNAYKDRGYETLIMDDEIDEAILNFITEYEGIKLKAINKN
ETSDELKDENFKKIEEEFQDILSKIKEILKDHVKDVSLSATLVQEPSAIIIDSTDPTYQMQKIMLSMGQEVKETKPILEL
NPNNKIIQNLKNLDDTTLEKISIILLEEAIITSGLPSKNPNQFINIINEMLEKNI

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=672, Percent_Identity=36.1607142857143, Blast_Score=381, Evalue=1e-105,
Organism=Homo sapiens, GI155722983, Length=634, Percent_Identity=30.2839116719243, Blast_Score=339, Evalue=4e-93,
Organism=Homo sapiens, GI154146191, Length=407, Percent_Identity=34.6437346437346, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI153792590, Length=407, Percent_Identity=34.6437346437346, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI4507677, Length=411, Percent_Identity=29.9270072992701, Blast_Score=213, Evalue=3e-55,
Organism=Escherichia coli, GI1786679, Length=622, Percent_Identity=41.9614147909968, Blast_Score=505, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17559162, Length=657, Percent_Identity=37.1385083713851, Blast_Score=397, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17542208, Length=667, Percent_Identity=35.832083958021, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI115535205, Length=641, Percent_Identity=31.8252730109204, Blast_Score=303, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI115535167, Length=430, Percent_Identity=37.6744186046512, Blast_Score=273, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6323840, Length=672, Percent_Identity=35.7142857142857, Blast_Score=388, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6325016, Length=407, Percent_Identity=35.3808353808354, Blast_Score=253, Evalue=6e-68,
Organism=Drosophila melanogaster, GI17647529, Length=679, Percent_Identity=35.7879234167894, Blast_Score=380, Evalue=1e-105,
Organism=Drosophila melanogaster, GI21357739, Length=677, Percent_Identity=34.2688330871492, Blast_Score=373, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24586016, Length=655, Percent_Identity=31.6030534351145, Blast_Score=333, Evalue=3e-91,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 70938; Mature: 70938

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQFDTEVNDLLYLIIHSLYSHKEIFLRELISNASDAIDKLKFLNITDEKFKDIKLDPR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHCCCCCCC
IDINFDEKSITIKDNGIGMNREDLISHLGTIAKSGTKEFINNLKKDEKKASSLIGQFGVG
EEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FYSAFIVADKVEVITKKALDNIAYIWSSDGKTGYEINETNKDENGTEIILHLNKEGTEYA
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEECCCCCCCCCCEEEEEECCCCCHHH
NKWKIQEIIKKYSNHISYPIFIKYREPIMKDGKQEGFEEKEDKLNDTTAIWTKNKNEISN
HHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCHHCCCHHHHHHCCCCEEEEECCCCCCCC
EEYNEFYKNLAFDYENPLIHIHTKAEGSIEYTNLFYVPSKASYDLYYPNTKPGVKLFINR
HHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCEEEECCCCCCCHHHHEEH
IFISDSADSLLPNYLRFIKGIIDCQDLPLNVSREILQKNKTLAKIKASSVKKILSELEKL
HEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SENDPTKFNEFSKEFGRCLKEGVYSDFDNRNKLISLIRFKSSNVNGFVSLKEYKDRMPAE
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHCCCC
QKSIYYITGGKENILKINPIVNAYKDRGYETLIMDDEIDEAILNFITEYEGIKLKAINKN
CCEEEEEECCCCCEEEECHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCC
ETSDELKDENFKKIEEEFQDILSKIKEILKDHVKDVSLSATLVQEPSAIIIDSTDPTYQM
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCCEEEEECCCCHHHH
QKIMLSMGQEVKETKPILELNPNNKIIQNLKNLDDTTLEKISIILLEEAIITSGLPSKNP
HHHHHHHCHHHHHCCCCEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCH
NQFINIINEMLEKNI
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKQFDTEVNDLLYLIIHSLYSHKEIFLRELISNASDAIDKLKFLNITDEKFKDIKLDPR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHCCCCCCC
IDINFDEKSITIKDNGIGMNREDLISHLGTIAKSGTKEFINNLKKDEKKASSLIGQFGVG
EEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FYSAFIVADKVEVITKKALDNIAYIWSSDGKTGYEINETNKDENGTEIILHLNKEGTEYA
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEECCCCCCCCCCEEEEEECCCCCHHH
NKWKIQEIIKKYSNHISYPIFIKYREPIMKDGKQEGFEEKEDKLNDTTAIWTKNKNEISN
HHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCHHCCCHHHHHHCCCCEEEEECCCCCCCC
EEYNEFYKNLAFDYENPLIHIHTKAEGSIEYTNLFYVPSKASYDLYYPNTKPGVKLFINR
HHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCEEEECCCCCCCHHHHEEH
IFISDSADSLLPNYLRFIKGIIDCQDLPLNVSREILQKNKTLAKIKASSVKKILSELEKL
HEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SENDPTKFNEFSKEFGRCLKEGVYSDFDNRNKLISLIRFKSSNVNGFVSLKEYKDRMPAE
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHCCCC
QKSIYYITGGKENILKINPIVNAYKDRGYETLIMDDEIDEAILNFITEYEGIKLKAINKN
CCEEEEEECCCCCEEEECHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCC
ETSDELKDENFKKIEEEFQDILSKIKEILKDHVKDVSLSATLVQEPSAIIIDSTDPTYQM
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCCEEEEECCCCHHHH
QKIMLSMGQEVKETKPILELNPNNKIIQNLKNLDDTTLEKISIILLEEAIITSGLPSKNP
HHHHHHHCHHHHHCCCCEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCH
NQFINIINEMLEKNI
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA