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The map label for this gene is trsA [H]

Identifier: 203283935

GI number: 203283935

Start: 17216

End: 18268

Strand: Reverse

Name: trsA [H]

Synonym: BDU_11

Alternate gene names: 203283935

Gene position: 18268-17216 (Counterclockwise)

Preceding gene: 203283936

Following gene: 203283933

Centisome position: 1.96

GC content: 30.2

Gene sequence:

>1053_bases
TTGATGCAAAAAAAAGTTATTCTTACAGGTGATAGACCTACAGGTTCTCTTCATTTGGGGCATTATGTGGGATCTATTGT
TAACAGATTAAAGTATCAGGAAGAGTATGAGACTTATATTATTATAGCGGATTTACATACTCTTACTACACAATCAGACC
TAAAGAGCATTAATGAGATATCAATTAATGTTAGAGAAATAGTTTTGGATTATTTGTCTTGTGGAATTGATCCTGAGAGA
GTTAATATTTATTTGCAATCAGCAATACCTGAGCTTTTAGAGTTAAATTTAATATTATCAATGATTGTTATGGTTAATCG
TTTGCAAAGAATTCCTAGTATAAAAGATATGAGCATTAATGCTGGACTGAGTGAAATTCCTTATGGGCTATTAGGTTATC
CTGTTTTAATGAGTGCAGATATTTTAATGGCAAAGGCTGATTTTGTTCCTGTTGGACGTGATAATGAATCTCATATTGAG
CTTACAAGAGAACTTGCTAGAAAATTTAATTTTCTTTATGGTGAGAATTTTTTTCCAATTCCTGAAGCTATATTTACGGA
TTTTCATACTCTTGTGGGAATTGATGGTAAAACTAAGATGAGTAAAAGTCTTGGTAATGCAATATTTTTAAATGATGATG
AAAAATCATTACGCAAAAAAGTTATGTCTATGTTTACAGATCCAAAAAGAATAAGAGCGGATATACCGGGAGAAGTTGAT
GGTAATCCTGTTTTTATTTATCATGATCTTTTTAATAGTGATATGGATGAGCTTTGTGAACTTAAGAGTAGATATAAAAA
AGGTACAATTGGAGATATTGAAGTTAAAGAGAGACTTTTTAATGTTTTAAATCAATTCTTAATTCCAATTAGGGAGAGAA
GAGAATTCTTTAAAGCTAAGAAGGGTTATGTTGATGAGATAATTTTTGAAGGTACAAATAAGGCTCGAAAGGTTGCATTA
GAAACTGTAAGAGATGCTAAGAATTTAATGGGTATATCAAAAACATGGAATGGAATTAGAAGGAATATAGAAAAAATGGC
GAAATATAAATAA

Upstream 100 bases:

>100_bases
TAGATAATATAGTATATTTGCGACCTTTTTCTGTATTTTTAAGTGGTTCTAAGATATTAACCCTTGATAATATTGATAAT
AATTTTAATAATAAGGAAAA

Downstream 100 bases:

>100_bases
AAAAGTAATTTTGAGTATTAATTGTTTTAATTGTGGCTATAAAGTAAATTGTTAATTTTTATTTTCAGTGTTGAGATTAT
ATTATTGAGTTTGCACTTTT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MMQKKVILTGDRPTGSLHLGHYVGSIVNRLKYQEEYETYIIIADLHTLTTQSDLKSINEISINVREIVLDYLSCGIDPER
VNIYLQSAIPELLELNLILSMIVMVNRLQRIPSIKDMSINAGLSEIPYGLLGYPVLMSADILMAKADFVPVGRDNESHIE
LTRELARKFNFLYGENFFPIPEAIFTDFHTLVGIDGKTKMSKSLGNAIFLNDDEKSLRKKVMSMFTDPKRIRADIPGEVD
GNPVFIYHDLFNSDMDELCELKSRYKKGTIGDIEVKERLFNVLNQFLIPIRERREFFKAKKGYVDEIIFEGTNKARKVAL
ETVRDAKNLMGISKTWNGIRRNIEKMAKYK

Sequences:

>Translated_350_residues
MMQKKVILTGDRPTGSLHLGHYVGSIVNRLKYQEEYETYIIIADLHTLTTQSDLKSINEISINVREIVLDYLSCGIDPER
VNIYLQSAIPELLELNLILSMIVMVNRLQRIPSIKDMSINAGLSEIPYGLLGYPVLMSADILMAKADFVPVGRDNESHIE
LTRELARKFNFLYGENFFPIPEAIFTDFHTLVGIDGKTKMSKSLGNAIFLNDDEKSLRKKVMSMFTDPKRIRADIPGEVD
GNPVFIYHDLFNSDMDELCELKSRYKKGTIGDIEVKERLFNVLNQFLIPIRERREFFKAKKGYVDEIIFEGTNKARKVAL
ETVRDAKNLMGISKTWNGIRRNIEKMAKYK
>Mature_350_residues
MMQKKVILTGDRPTGSLHLGHYVGSIVNRLKYQEEYETYIIIADLHTLTTQSDLKSINEISINVREIVLDYLSCGIDPER
VNIYLQSAIPELLELNLILSMIVMVNRLQRIPSIKDMSINAGLSEIPYGLLGYPVLMSADILMAKADFVPVGRDNESHIE
LTRELARKFNFLYGENFFPIPEAIFTDFHTLVGIDGKTKMSKSLGNAIFLNDDEKSLRKKVMSMFTDPKRIRADIPGEVD
GNPVFIYHDLFNSDMDELCELKSRYKKGTIGDIEVKERLFNVLNQFLIPIRERREFFKAKKGYVDEIIFEGTNKARKVAL
ETVRDAKNLMGISKTWNGIRRNIEKMAKYK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=335, Percent_Identity=30.4477611940298, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI41352700, Length=184, Percent_Identity=39.6739130434783, Blast_Score=136, Evalue=4e-32,
Organism=Escherichia coli, GI1789786, Length=339, Percent_Identity=29.4985250737463, Blast_Score=162, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI71982800, Length=343, Percent_Identity=27.9883381924198, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI71982793, Length=343, Percent_Identity=27.9883381924198, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320474, Length=353, Percent_Identity=32.0113314447592, Blast_Score=143, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24666151, Length=343, Percent_Identity=32.3615160349854, Blast_Score=157, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 40139; Mature: 40139

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQKKVILTGDRPTGSLHLGHYVGSIVNRLKYQEEYETYIIIADLHTLTTQSDLKSINEI
CCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHH
SINVREIVLDYLSCGIDPERVNIYLQSAIPELLELNLILSMIVMVNRLQRIPSIKDMSIN
HHHHHHHHHHHHHCCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AGLSEIPYGLLGYPVLMSADILMAKADFVPVGRDNESHIELTRELARKFNFLYGENFFPI
CCHHHCCHHHHHHHHHHHHHHHEECCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PEAIFTDFHTLVGIDGKTKMSKSLGNAIFLNDDEKSLRKKVMSMFTDPKRIRADIPGEVD
HHHHHHHHHHHHCCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCHHHHCCCCCCCC
GNPVFIYHDLFNSDMDELCELKSRYKKGTIGDIEVKERLFNVLNQFLIPIRERREFFKAK
CCEEEEEHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGYVDEIIFEGTNKARKVALETVRDAKNLMGISKTWNGIRRNIEKMAKYK
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMQKKVILTGDRPTGSLHLGHYVGSIVNRLKYQEEYETYIIIADLHTLTTQSDLKSINEI
CCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHH
SINVREIVLDYLSCGIDPERVNIYLQSAIPELLELNLILSMIVMVNRLQRIPSIKDMSIN
HHHHHHHHHHHHHCCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AGLSEIPYGLLGYPVLMSADILMAKADFVPVGRDNESHIELTRELARKFNFLYGENFFPI
CCHHHCCHHHHHHHHHHHHHHHEECCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PEAIFTDFHTLVGIDGKTKMSKSLGNAIFLNDDEKSLRKKVMSMFTDPKRIRADIPGEVD
HHHHHHHHHHHHCCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCHHHHCCCCCCCC
GNPVFIYHDLFNSDMDELCELKSRYKKGTIGDIEVKERLFNVLNQFLIPIRERREFFKAK
CCEEEEEHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGYVDEIIFEGTNKARKVALETVRDAKNLMGISKTWNGIRRNIEKMAKYK
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]