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The map label for this gene is yabD [H]

Identifier: 197120298

GI number: 197120298

Start: 4474433

End: 4475212

Strand: Direct

Name: yabD [H]

Synonym: Gbem_3937

Alternate gene names: 197120298

Gene position: 4474433-4475212 (Clockwise)

Preceding gene: 197120297

Following gene: 197120299

Centisome position: 96.95

GC content: 64.49

Gene sequence:

>780_bases
GTGCTTTTCGACAGCCACTGCCACCTGGACGACCCGCGGCTCCTCCCCCACCTGGAGAGGCTCCTCCCGGAGGCAGAGGC
GGCAGGGGTCACCGCTTTCCTCGTCCCAGGTGTCGCGCCTCAGGGATGGCACCGGATCAGGACATTATCCGCAGCATATC
CCCAAATCTACCCCGCCTACGGCGTGCACCCCATGCACGCAGAACTACTCACCCCTCAGGCAGTGTCGGATTTATTCCAG
CTTGCCACCGGCGCCAGCGCCATCGGCGAAATAGGCCTCGACTACCTCCTCCCCTCCCCCTCGCGGCAGGTCCAGCAGCA
GGCCTTCAGGGTGCAGTTGCGCCTTGCCGCTGAAGCCCGGCTGCCGGTACTGCTTCATTGCCGCAAGGCGTTCGAGGACC
TTTTGGCAATCATCAGGGAAGAGGGCATTTGCGGCGGCGTCATGCACGCCTTCTCCGGTAGCCTCGATAGCGCCCGCAGT
TGCCTGCGCCTCGGCCTGCACATATCCCTCGCCGGGAGCGTCACCTACGCCAACGCTCGACGGCCGTTGGAGGTTGCCGC
AGGGATTCCGCTGGAGCGCCTGCTTTTGGAGACTGACGCCCCCGACCTGGCTCCGGAGCCCCACAGAGGAAGTGTCAACC
GTCCCTCCTATCTCCTGGAAACGGCTACCAGAGTGGCGCGCATCAAGGGTTTATCCCTCGAGGAGCTGGGTCGCGCCACC
ACCGGGAACGCAACCCGCCTCTTCCGGCTCCAAGGAAACACCTCCCAGCTAAACCTTTGA

Upstream 100 bases:

>100_bases
TTCACGTCCCGCCGAAGTTAGCATCTCGCAGTACATCTTTCAGCGCCAGGTCGAGATCATCAAGGAACTGAAGGAACATC
CGGCCATAGGCGGGTAAGCC

Downstream 100 bases:

>100_bases
ATTAACAAGCATTAACGTCCAAATTCCTCTCATTGACCTTGACATGCTCTCCGCTATACTCATTGCCAAGCAGTCCCACT
GAAGCCTACGGAGGTGCAGC

Product: TatD family magnesium-dependent deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLFDSHCHLDDPRLLPHLERLLPEAEAAGVTAFLVPGVAPQGWHRIRTLSAAYPQIYPAYGVHPMHAELLTPQAVSDLFQ
LATGASAIGEIGLDYLLPSPSRQVQQQAFRVQLRLAAEARLPVLLHCRKAFEDLLAIIREEGICGGVMHAFSGSLDSARS
CLRLGLHISLAGSVTYANARRPLEVAAGIPLERLLLETDAPDLAPEPHRGSVNRPSYLLETATRVARIKGLSLEELGRAT
TGNATRLFRLQGNTSQLNL

Sequences:

>Translated_259_residues
MLFDSHCHLDDPRLLPHLERLLPEAEAAGVTAFLVPGVAPQGWHRIRTLSAAYPQIYPAYGVHPMHAELLTPQAVSDLFQ
LATGASAIGEIGLDYLLPSPSRQVQQQAFRVQLRLAAEARLPVLLHCRKAFEDLLAIIREEGICGGVMHAFSGSLDSARS
CLRLGLHISLAGSVTYANARRPLEVAAGIPLERLLLETDAPDLAPEPHRGSVNRPSYLLETATRVARIKGLSLEELGRAT
TGNATRLFRLQGNTSQLNL
>Mature_259_residues
MLFDSHCHLDDPRLLPHLERLLPEAEAAGVTAFLVPGVAPQGWHRIRTLSAAYPQIYPAYGVHPMHAELLTPQAVSDLFQ
LATGASAIGEIGLDYLLPSPSRQVQQQAFRVQLRLAAEARLPVLLHCRKAFEDLLAIIREEGICGGVMHAFSGSLDSARS
CLRLGLHISLAGSVTYANARRPLEVAAGIPLERLLLETDAPDLAPEPHRGSVNRPSYLLETATRVARIKGLSLEELGRAT
TGNATRLFRLQGNTSQLNL

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=265, Percent_Identity=30.9433962264151, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI110349734, Length=265, Percent_Identity=30.5660377358491, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=30, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI226061614, Length=255, Percent_Identity=30.5882352941176, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI14042943, Length=205, Percent_Identity=30.7317073170732, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI225903424, Length=208, Percent_Identity=31.7307692307692, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI225903439, Length=164, Percent_Identity=32.3170731707317, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI226061595, Length=236, Percent_Identity=28.3898305084746, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1787342, Length=263, Percent_Identity=38.4030418250951, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI87082439, Length=254, Percent_Identity=33.4645669291339, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=30.1158301158301, Blast_Score=114, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=27.0462633451957, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71980746, Length=266, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17543026, Length=180, Percent_Identity=30, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17565396, Length=219, Percent_Identity=28.7671232876712, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24586117, Length=217, Percent_Identity=32.258064516129, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221330018, Length=217, Percent_Identity=32.258064516129, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648690, Length=284, Percent_Identity=29.5774647887324, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28165; Mature: 28165

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDSHCHLDDPRLLPHLERLLPEAEAAGVTAFLVPGVAPQGWHRIRTLSAAYPQIYPAY
CCCCCCCCCCCCHHHHHHHHHCCCHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCC
GVHPMHAELLTPQAVSDLFQLATGASAIGEIGLDYLLPSPSRQVQQQAFRVQLRLAAEAR
CCCCHHHHHCCHHHHHHHHHHHHCHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHCCC
LPVLLHCRKAFEDLLAIIREEGICGGVMHAFSGSLDSARSCLRLGLHISLAGSVTYANAR
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCEEEEECCEEECCCC
RPLEVAAGIPLERLLLETDAPDLAPEPHRGSVNRPSYLLETATRVARIKGLSLEELGRAT
CCHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
TGNATRLFRLQGNTSQLNL
CCCCEEEEEEECCCCCCCC
>Mature Secondary Structure
MLFDSHCHLDDPRLLPHLERLLPEAEAAGVTAFLVPGVAPQGWHRIRTLSAAYPQIYPAY
CCCCCCCCCCCCHHHHHHHHHCCCHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCC
GVHPMHAELLTPQAVSDLFQLATGASAIGEIGLDYLLPSPSRQVQQQAFRVQLRLAAEAR
CCCCHHHHHCCHHHHHHHHHHHHCHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHCCC
LPVLLHCRKAFEDLLAIIREEGICGGVMHAFSGSLDSARSCLRLGLHISLAGSVTYANAR
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCEEEEECCEEECCCC
RPLEVAAGIPLERLLLETDAPDLAPEPHRGSVNRPSYLLETATRVARIKGLSLEELGRAT
CCHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
TGNATRLFRLQGNTSQLNL
CCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]