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The map label for this gene is 197119237

Identifier: 197119237

GI number: 197119237

Start: 3293907

End: 3295097

Strand: Direct

Name: 197119237

Synonym: Gbem_2864

Alternate gene names: NA

Gene position: 3293907-3295097 (Clockwise)

Preceding gene: 197119235

Following gene: 197119238

Centisome position: 71.37

GC content: 61.29

Gene sequence:

>1191_bases
ATGGGTACGTCAGTTGGAATAGGCTTCAGCACCCGGAAAAGCCCGATGGATGCCGGGAATGAGGCAGCCCGGACGGCACT
GGAACAGGCCGGCATCGCCAAGCCGGACCTCGTCCTCGTCTTCGCCACGGTAGGCTACCACCAGCAGCAGTTGATCGGCG
CCATCCGCGAGGCGACGTCCGGGGCGCCTCTTTGCGGCTGTTCCGGCGAGGGGATCATCGTGCAGGATGCCGTGGTGGAA
ACGAATTTCGCTGTCGGTGTCATGGTGATCGCCTCCGACGAAGTAAGCTTCGGCATCACCTCCGTCACCGGGATAGGCGA
AGAGCCTTGCGCGGCCGGCAAGAAGCTGGCAGCGCAGATCACCCCGCTTCTGGCAGACGACAGCCGCGCCTTTTTCCTGC
TGGCGGACGGCCTGGCATTCGATTTCGATCCCTTTGTGGCAGCCTTCGAGTCGGTTCTCCCCTCTTCCGCCAAGCTCCCG
ATCTTCGGAGGCCTCGCCGCGGACAACTGGGCTTCCCGCAGGACCTACCAGTACCACGACGGCGAGATATTGAGCCAAGG
CGCCTGCTGTATCGTCATGTCGGGCAGGTGCCGCGTCGCCTGGGGCATCAACCACGGCTGCGTTCCGGTCGGGGCGAAGC
GCACCATCACGCGCAGCAAGGGAAACATCATCTACGAGATCGATGGGACCCCGGCCTTGGATGTGCTCAAGGAATACGTA
GACGAGGACTGGGCGGTCAAGTGGAACAAGGCGACCCTGAACCTCGGGCTCGGGTTCAAGACACCGGAGCACCTAAGGGA
GCGGTACGACGAGTACTACGTGCGGTACATAATGGCAAAGGACGACGAGGCAGGCTCCGTCACCATCCAGTCCGACGTCA
CGGACGGAACCCCCCTCTGGATCGTCCGCCGCGACAAGGAACTGATGATGGACGGCCTCAAGTCCATTCCACGGCAGATC
AAAGAAGATCTTGCCGGACAAAAGCCCAAACTGGTGCTGCAGTTCGAGTGCATGGGACGGGGCCGGGTCGTATTCAAGGA
GCAGGAACGCATGGACCTGGTGAAATGCCTCCAGCGCGACCTGGGCGAGGACCTCCCCTGGCTCGGCTTTTATACCTATG
GGGAAATAGGTCCGATCAGCAGGTACAACTGCTTCCACAACTTCACCTCAGTCGTAGCGGTAGTCTACTAA

Upstream 100 bases:

>100_bases
TCATCCGTTTTTGCCCCTGGAATACAGGCAGTTCCGGGCAAGGGAACAAGCAGTCGAGCCAGCGGGGTTCGTAGAGAGCG
CCTGCAGCAGGAGTAAACCC

Downstream 100 bases:

>100_bases
GGTCGGGCGGTCGGGTACATGGACAAAATGAATAGAGATACGCTGACGGTGGAACTGGAAAGGCTGCGGCAGGAAAACGA
GGTCCTCTCCGGGCAGGTCA

Product: FIST domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MGTSVGIGFSTRKSPMDAGNEAARTALEQAGIAKPDLVLVFATVGYHQQQLIGAIREATSGAPLCGCSGEGIIVQDAVVE
TNFAVGVMVIASDEVSFGITSVTGIGEEPCAAGKKLAAQITPLLADDSRAFFLLADGLAFDFDPFVAAFESVLPSSAKLP
IFGGLAADNWASRRTYQYHDGEILSQGACCIVMSGRCRVAWGINHGCVPVGAKRTITRSKGNIIYEIDGTPALDVLKEYV
DEDWAVKWNKATLNLGLGFKTPEHLRERYDEYYVRYIMAKDDEAGSVTIQSDVTDGTPLWIVRRDKELMMDGLKSIPRQI
KEDLAGQKPKLVLQFECMGRGRVVFKEQERMDLVKCLQRDLGEDLPWLGFYTYGEIGPISRYNCFHNFTSVVAVVY

Sequences:

>Translated_396_residues
MGTSVGIGFSTRKSPMDAGNEAARTALEQAGIAKPDLVLVFATVGYHQQQLIGAIREATSGAPLCGCSGEGIIVQDAVVE
TNFAVGVMVIASDEVSFGITSVTGIGEEPCAAGKKLAAQITPLLADDSRAFFLLADGLAFDFDPFVAAFESVLPSSAKLP
IFGGLAADNWASRRTYQYHDGEILSQGACCIVMSGRCRVAWGINHGCVPVGAKRTITRSKGNIIYEIDGTPALDVLKEYV
DEDWAVKWNKATLNLGLGFKTPEHLRERYDEYYVRYIMAKDDEAGSVTIQSDVTDGTPLWIVRRDKELMMDGLKSIPRQI
KEDLAGQKPKLVLQFECMGRGRVVFKEQERMDLVKCLQRDLGEDLPWLGFYTYGEIGPISRYNCFHNFTSVVAVVY
>Mature_395_residues
GTSVGIGFSTRKSPMDAGNEAARTALEQAGIAKPDLVLVFATVGYHQQQLIGAIREATSGAPLCGCSGEGIIVQDAVVET
NFAVGVMVIASDEVSFGITSVTGIGEEPCAAGKKLAAQITPLLADDSRAFFLLADGLAFDFDPFVAAFESVLPSSAKLPI
FGGLAADNWASRRTYQYHDGEILSQGACCIVMSGRCRVAWGINHGCVPVGAKRTITRSKGNIIYEIDGTPALDVLKEYVD
EDWAVKWNKATLNLGLGFKTPEHLRERYDEYYVRYIMAKDDEAGSVTIQSDVTDGTPLWIVRRDKELMMDGLKSIPRQIK
EDLAGQKPKLVLQFECMGRGRVVFKEQERMDLVKCLQRDLGEDLPWLGFYTYGEIGPISRYNCFHNFTSVVAVVY

Specific function: Unknown

COG id: COG3287

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv0874c [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019494
- InterPro:   IPR013702
- InterPro:   IPR016741 [H]

Pfam domain/function: PF08495 FIST; PF10442 FIST_C [H]

EC number: NA

Molecular weight: Translated: 43265; Mature: 43134

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTSVGIGFSTRKSPMDAGNEAARTALEQAGIAKPDLVLVFATVGYHQQQLIGAIREATS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCC
GAPLCGCSGEGIIVQDAVVETNFAVGVMVIASDEVSFGITSVTGIGEEPCAAGKKLAAQI
CCCEECCCCCCEEEEEEEEECCCEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHH
TPLLADDSRAFFLLADGLAFDFDPFVAAFESVLPSSAKLPIFGGLAADNWASRRTYQYHD
CCEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCEEEECC
GEILSQGACCIVMSGRCRVAWGINHGCVPVGAKRTITRSKGNIIYEIDGTPALDVLKEYV
CCEECCCCEEEEECCCEEEEECCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHH
DEDWAVKWNKATLNLGLGFKTPEHLRERYDEYYVRYIMAKDDEAGSVTIQSDVTDGTPLW
CCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHEEEEEEECCCCCCEEEEECCCCCCCEEE
IVRRDKELMMDGLKSIPRQIKEDLAGQKPKLVLQFECMGRGRVVFKEQERMDLVKCLQRD
EEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHH
LGEDLPWLGFYTYGEIGPISRYNCFHNFTSVVAVVY
HCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHEEEC
>Mature Secondary Structure 
GTSVGIGFSTRKSPMDAGNEAARTALEQAGIAKPDLVLVFATVGYHQQQLIGAIREATS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCC
GAPLCGCSGEGIIVQDAVVETNFAVGVMVIASDEVSFGITSVTGIGEEPCAAGKKLAAQI
CCCEECCCCCCEEEEEEEEECCCEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHH
TPLLADDSRAFFLLADGLAFDFDPFVAAFESVLPSSAKLPIFGGLAADNWASRRTYQYHD
CCEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCEEEECC
GEILSQGACCIVMSGRCRVAWGINHGCVPVGAKRTITRSKGNIIYEIDGTPALDVLKEYV
CCEECCCCEEEEECCCEEEEECCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHH
DEDWAVKWNKATLNLGLGFKTPEHLRERYDEYYVRYIMAKDDEAGSVTIQSDVTDGTPLW
CCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHEEEEEEECCCCCCEEEEECCCCCCCEEE
IVRRDKELMMDGLKSIPRQIKEDLAGQKPKLVLQFECMGRGRVVFKEQERMDLVKCLQRD
EEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHH
LGEDLPWLGFYTYGEIGPISRYNCFHNFTSVVAVVY
HCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]