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The map label for this gene is apl-4 [H]

Identifier: 197119213

GI number: 197119213

Start: 3268932

End: 3270917

Strand: Reverse

Name: apl-4 [H]

Synonym: Gbem_2840

Alternate gene names: 197119213

Gene position: 3270917-3268932 (Counterclockwise)

Preceding gene: 197119214

Following gene: 197119212

Centisome position: 70.87

GC content: 64.1

Gene sequence:

>1986_bases
ATGAAAAAAAGAATCGCCGCCATAACGCTCGCTCTTACGTTCTCCGTTTGCGCCGCCGCTCCCCTCGCAGTCGCAGCCTC
GGTCGGCACCGCCGCACCGCAGTCACCGGCAATAGCAGCGCCTGCGGCAACAGTTGCACCTGCAGCCGCCACCGCGGCAG
CGCCCACCGCAGCCAAGGCCGCTCCGGCCAAGGGCGCGGACACCCAGCCCGCCAAGGTGACCCCCAACCGCGGCATCACC
ATCGGCATGTTCGCGCTCATCATCGCCATCACCATGGGGGTGGTGGTCTGGGCCGCGAAGAAGACGCAGACCGCCGCCGA
CTTCTACACCGCAGGCGGAGGGATCACCGGCCTCCAAAACGGCTGGGCCATAGCCGGCGACTACATGTCGGCCGCCTCTT
TCCTCGGCATGTCGGGGCTCATCTCGCTCTACGGCATCGACGGCTTCATGTACGCGGTGGGGCCGATGTTCTCGTTCATC
GCCATCCTGCTGGTCATCGCCGAGCCCTGCCGCAACGCCGGCAAGTACACGCTGGGCGACATCCTCTCCTTCAGGTCGTC
GCCCAAGGTGGTGCGCGGCGTAGCGGCGCTCTCCACCGTCACCGTCTCGATCTTCTACCTGATCGCGCAGATGGTCGGCG
CGGGGAAGCTGATGCAGATGCTGATCGGGATCCCTTACCGCGTCTCGGTCATCGGGGTCGGGGCCCTCATGGTCGCCTAC
GTCGTCTTCGGCGGCATGAAAGCCACTACCTGGGTCCAGATCATCAAGGCCTCGCTCTTGATGGGCGCCACCACGCTTTT
GTGCATCCTGGTCGCGGCGAAGGCGGGCTTCAACCCGGTCTCCTTCTTCACCGACATCGTGAACAACCCGGCCATCCAGG
ATCACGTCAGGCTGAACGTACTGAAGGACGCCATTCCCAAGGCGGGGGTGGATTACGGCCAGCGCTTCCTGGAGCCCGGG
CTCTTCCTGAAAAGCCCGCTGGATCAGATCTCGCTCGGTATCGCCTGGGCGCTTGGCGCAGCCGGCCTGCCGCACATCCT
GATGCGCTTTTTCACGGTTCCCAGCGCCAAGGAAGCGCGCAAGTCGATCATCATCGCCCTTTTCCTTAACTCCACCTTCT
TCTTCATGATCAGCATCATCGGCTTCGGCGCAGCGCTCTACCTGACCCCCCAGGGCATCCTGGCGGTGGACAAAGGTGGG
AACATGGCGACGCTCTTATTGGCACAGCACATGGGTGGGGGCGCCGGGAGCCTCGGCGGAGACGTCTTCCTGGCCTTCAT
CTGCGCCGTAGCCTTCGCCACTATCCTCGCCGTCGTCTCCGGTCTCGTGCTCGCAGCCTCCGCGGCCATCGCCCACGACG
TCTATGTCAACATCATCAAGGACGGCAAGGCCGACCAGCACCTGCAGGTGAAGGTGGCGCGCATCACCTCCCTTTTCGTC
GGCACCTCCGCCATCCTGATGGGGCTTGCCGCCGAGAAGGAGAACGTGGTCGCCCTGGTGGCGCTCGCCTTCGCGGTCGC
CGCCTCGGGGAACTTCCCGGTGGTCATGCTCTCGCTCTTCTGGAAGAAGTTCAACACCGCGGGGATCGTTTCCGGCCTCG
TGGTCGGGACCGTCACCGCCCTCGCGCTGGTGATGGTGTCGCCGGTGATGACCTATCCCAAGAAGGTCGCGGCCGACGCG
AAGAAGATCGTCGAGACCCTGGAAAAGAAGCAGGCAACGGGCGTGGCGCTGGCGGACAAGGAGCTGAAGACCCTGGAGAA
GTCCCGGGTGGAATATGAGAAGAACAAGGATGGCAGCTCCATGGTCGGGCTCGATAAGCCGATATTCCCGCTGAAGAACC
CGGGTATCGTCTCGGTGCCCCTCGGGTTCCTGGCCGCCGTATTTGGTTGCCTCTTGTTCCGCGACCGCCGCGCCGAAGAC
ATGTTCGCCGAGATCGACGTGCGGCAGAACACCGGCCTCGGGATAGCCAAGGCGACAGATCACTAG

Upstream 100 bases:

>100_bases
GCCATCGGCGTCGCGGCCTACTACGCCCACGTCGCCAACAAGGATTTCGACCGGCTGACCAAGCAGCTGCTTGACGTGCT
TAATTAAAGGAGGGGACAGC

Downstream 100 bases:

>100_bases
CAACTTCCCGCCCCCGGAGGGGGAGGGCCAGGGAGGGGGTATCATGCGCTCAAGGGGGACAGGCACCTGGCGGAGCCAGT
CCCCTCTTCCCCCCTCCCGG

Product: sodium/solute symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MKKRIAAITLALTFSVCAAAPLAVAASVGTAAPQSPAIAAPAATVAPAAATAAAPTAAKAAPAKGADTQPAKVTPNRGIT
IGMFALIIAITMGVVVWAAKKTQTAADFYTAGGGITGLQNGWAIAGDYMSAASFLGMSGLISLYGIDGFMYAVGPMFSFI
AILLVIAEPCRNAGKYTLGDILSFRSSPKVVRGVAALSTVTVSIFYLIAQMVGAGKLMQMLIGIPYRVSVIGVGALMVAY
VVFGGMKATTWVQIIKASLLMGATTLLCILVAAKAGFNPVSFFTDIVNNPAIQDHVRLNVLKDAIPKAGVDYGQRFLEPG
LFLKSPLDQISLGIAWALGAAGLPHILMRFFTVPSAKEARKSIIIALFLNSTFFFMISIIGFGAALYLTPQGILAVDKGG
NMATLLLAQHMGGGAGSLGGDVFLAFICAVAFATILAVVSGLVLAASAAIAHDVYVNIIKDGKADQHLQVKVARITSLFV
GTSAILMGLAAEKENVVALVALAFAVAASGNFPVVMLSLFWKKFNTAGIVSGLVVGTVTALALVMVSPVMTYPKKVAADA
KKIVETLEKKQATGVALADKELKTLEKSRVEYEKNKDGSSMVGLDKPIFPLKNPGIVSVPLGFLAAVFGCLLFRDRRAED
MFAEIDVRQNTGLGIAKATDH

Sequences:

>Translated_661_residues
MKKRIAAITLALTFSVCAAAPLAVAASVGTAAPQSPAIAAPAATVAPAAATAAAPTAAKAAPAKGADTQPAKVTPNRGIT
IGMFALIIAITMGVVVWAAKKTQTAADFYTAGGGITGLQNGWAIAGDYMSAASFLGMSGLISLYGIDGFMYAVGPMFSFI
AILLVIAEPCRNAGKYTLGDILSFRSSPKVVRGVAALSTVTVSIFYLIAQMVGAGKLMQMLIGIPYRVSVIGVGALMVAY
VVFGGMKATTWVQIIKASLLMGATTLLCILVAAKAGFNPVSFFTDIVNNPAIQDHVRLNVLKDAIPKAGVDYGQRFLEPG
LFLKSPLDQISLGIAWALGAAGLPHILMRFFTVPSAKEARKSIIIALFLNSTFFFMISIIGFGAALYLTPQGILAVDKGG
NMATLLLAQHMGGGAGSLGGDVFLAFICAVAFATILAVVSGLVLAASAAIAHDVYVNIIKDGKADQHLQVKVARITSLFV
GTSAILMGLAAEKENVVALVALAFAVAASGNFPVVMLSLFWKKFNTAGIVSGLVVGTVTALALVMVSPVMTYPKKVAADA
KKIVETLEKKQATGVALADKELKTLEKSRVEYEKNKDGSSMVGLDKPIFPLKNPGIVSVPLGFLAAVFGCLLFRDRRAED
MFAEIDVRQNTGLGIAKATDH
>Mature_661_residues
MKKRIAAITLALTFSVCAAAPLAVAASVGTAAPQSPAIAAPAATVAPAAATAAAPTAAKAAPAKGADTQPAKVTPNRGIT
IGMFALIIAITMGVVVWAAKKTQTAADFYTAGGGITGLQNGWAIAGDYMSAASFLGMSGLISLYGIDGFMYAVGPMFSFI
AILLVIAEPCRNAGKYTLGDILSFRSSPKVVRGVAALSTVTVSIFYLIAQMVGAGKLMQMLIGIPYRVSVIGVGALMVAY
VVFGGMKATTWVQIIKASLLMGATTLLCILVAAKAGFNPVSFFTDIVNNPAIQDHVRLNVLKDAIPKAGVDYGQRFLEPG
LFLKSPLDQISLGIAWALGAAGLPHILMRFFTVPSAKEARKSIIIALFLNSTFFFMISIIGFGAALYLTPQGILAVDKGG
NMATLLLAQHMGGGAGSLGGDVFLAFICAVAFATILAVVSGLVLAASAAIAHDVYVNIIKDGKADQHLQVKVARITSLFV
GTSAILMGLAAEKENVVALVALAFAVAASGNFPVVMLSLFWKKFNTAGIVSGLVVGTVTALALVMVSPVMTYPKKVAADA
KKIVETLEKKQATGVALADKELKTLEKSRVEYEKNKDGSSMVGLDKPIFPLKNPGIVSVPLGFLAAVFGCLLFRDRRAED
MFAEIDVRQNTGLGIAKATDH

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Escherichia coli, GI1790503, Length=623, Percent_Identity=38.3627608346709, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI87082237, Length=468, Percent_Identity=24.5726495726496, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787251, Length=475, Percent_Identity=25.0526315789474, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 68599; Mature: 68599

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3 ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRIAAITLALTFSVCAAAPLAVAASVGTAAPQSPAIAAPAATVAPAAATAAAPTAAKA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCHHHHHCCCCHHCC
APAKGADTQPAKVTPNRGITIGMFALIIAITMGVVVWAAKKTQTAADFYTAGGGITGLQN
CCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCC
GWAIAGDYMSAASFLGMSGLISLYGIDGFMYAVGPMFSFIAILLVIAEPCRNAGKYTLGD
CCEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ILSFRSSPKVVRGVAALSTVTVSIFYLIAQMVGAGKLMQMLIGIPYRVSVIGVGALMVAY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEHHHHHHHHHHHH
VVFGGMKATTWVQIIKASLLMGATTLLCILVAAKAGFNPVSFFTDIVNNPAIQDHVRLNV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
LKDAIPKAGVDYGQRFLEPGLFLKSPLDQISLGIAWALGAAGLPHILMRFFTVPSAKEAR
HHHHCCCCCHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHH
KSIIIALFLNSTFFFMISIIGFGAALYLTPQGILAVDKGGNMATLLLAQHMGGGAGSLGG
HHEEEEHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCEEHHHHHHHCCCCCCCCHH
DVFLAFICAVAFATILAVVSGLVLAASAAIAHDVYVNIIKDGKADQHLQVKVARITSLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHEEHHHHHHHHHH
GTSAILMGLAAEKENVVALVALAFAVAASGNFPVVMLSLFWKKFNTAGIVSGLVVGTVTA
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LALVMVSPVMTYPKKVAADAKKIVETLEKKQATGVALADKELKTLEKSRVEYEKNKDGSS
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHCCCCCCC
MVGLDKPIFPLKNPGIVSVPLGFLAAVFGCLLFRDRRAEDMFAEIDVRQNTGLGIAKATD
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHEEEECCCCCCCCCCCC
H
C
>Mature Secondary Structure
MKKRIAAITLALTFSVCAAAPLAVAASVGTAAPQSPAIAAPAATVAPAAATAAAPTAAKA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCHHHHHCCCCHHCC
APAKGADTQPAKVTPNRGITIGMFALIIAITMGVVVWAAKKTQTAADFYTAGGGITGLQN
CCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCC
GWAIAGDYMSAASFLGMSGLISLYGIDGFMYAVGPMFSFIAILLVIAEPCRNAGKYTLGD
CCEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ILSFRSSPKVVRGVAALSTVTVSIFYLIAQMVGAGKLMQMLIGIPYRVSVIGVGALMVAY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEHHHHHHHHHHHH
VVFGGMKATTWVQIIKASLLMGATTLLCILVAAKAGFNPVSFFTDIVNNPAIQDHVRLNV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
LKDAIPKAGVDYGQRFLEPGLFLKSPLDQISLGIAWALGAAGLPHILMRFFTVPSAKEAR
HHHHCCCCCHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHH
KSIIIALFLNSTFFFMISIIGFGAALYLTPQGILAVDKGGNMATLLLAQHMGGGAGSLGG
HHEEEEHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCEEHHHHHHHCCCCCCCCHH
DVFLAFICAVAFATILAVVSGLVLAASAAIAHDVYVNIIKDGKADQHLQVKVARITSLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHEEHHHHHHHHHH
GTSAILMGLAAEKENVVALVALAFAVAASGNFPVVMLSLFWKKFNTAGIVSGLVVGTVTA
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LALVMVSPVMTYPKKVAADAKKIVETLEKKQATGVALADKELKTLEKSRVEYEKNKDGSS
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHCCCCCCC
MVGLDKPIFPLKNPGIVSVPLGFLAAVFGCLLFRDRRAEDMFAEIDVRQNTGLGIAKATD
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHEEEECCCCCCCCCCCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]