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The map label for this gene is pepQ [H]

Identifier: 197119209

GI number: 197119209

Start: 3263035

End: 3264201

Strand: Reverse

Name: pepQ [H]

Synonym: Gbem_2836

Alternate gene names: 197119209

Gene position: 3264201-3263035 (Counterclockwise)

Preceding gene: 197119210

Following gene: 197119208

Centisome position: 70.73

GC content: 61.01

Gene sequence:

>1167_bases
ATGCTGAACAAGCAGGAATCGCAACAGAGAATCACCAGGCTGCAACAGGAACTTAAGGCAAAGGGTATCGACGGAGCGCT
CTTCATCTACCCCATCGACGTCTACTATTTCACCGGCACCCGCCAGAATTCGACGCTCTGGGTCCCGGCCGAGGGGAAAC
CGCGGCTGATGGTGCGGAAAAGCGTCTCCAGGGCGATCAAGGAAAGCTGCATCGAGGAGACTGTCCCCTTTCCGTCCAGT
AAGGAGTTTCCGGCGCTGTTTCCGCCCGAACTGCAGAAGATCGGCTTCACCTTCGACGTGGCGCCGGTGCAGCAGTACAA
CTACTACGCGAAGCTTTTGCCGGGGCGCGAGTTCGTCGACGTCTCTGCCATCAACCGCGAGATCCGCTCGGTGAAGTCTG
AGTGGGAACTGGGGCAGATGCGGAAAAGCGGCGACATGATCTGCCAGGTCTTCAGGGAGGTGCCGGGATTCCTGAAGGAG
GGGATGCGCGAAGTTGACCTGGCGGCGGAGTTCGAATGCCGGCTCAGAAAGGCGGGGAGCGAAGGTTACGTGCGCATGCG
CGCCTTCAATCAGGAACTGTTCCAGGGGCTTGCCGTTTCATCCGCGGCCTGCGACCCCGGCTTCTTCGACGGCGCAGTGA
CCGGGCAGGGGATGTCCAGCGCCTCCCCGCATGGTGCTTCCGCCGCAGTAATCAAAGCCAATACCCCGATCCTCGTCGAC
TATACCGGCATCTTCAACGGTTACATCGTGGACATAACGCGCTTTTTCGTCATCGGCAAGCTGGCGCCCGAGTTGGAGCA
CGGCTTCGCCACGGCGCTCGCCATCCAGAAATACCTGGTCGACAATCTGAAGCCGGGGGTGATCTGCGAGGAGCTGTTCC
TGAAGGCGGCCGAAATGGCGGAGGAAGCTGGCCTCGGCCGGAACTTCATGGGGGCCCCCGGGGAGAACGCCAAGTTCGTT
GGTCACGGCGTCGGTCTCGAACTGGACGAGTTCCCGGTGCTGGCGCAAGGGTTCAAGGTGCCGCTGCGGGATGGGCAGAC
CATTGCCATCGAACCGAAGTTCGTCTTCCCGGGTCAGGGTGTGGCCGGAATAGAGAACACCTTTGCGGTCGGCAAAAACG
GCGGCGTGAAGCTGACCGACATGCCGGACGAGGTCGTGTACCTGTAG

Upstream 100 bases:

>100_bases
ATCGGCGTGACCCCGCTCGGGTATCCCGACCAGGATCCCAAACAGCGCCCGCGCAAGGATTTGAATGAAATTGCCTACTA
CAACGATTGGGGGGTGACGG

Downstream 100 bases:

>100_bases
CAGGATCCCTTCGCACTGTGTCCATCACAGAGAATCAGCAGTTGCAGTTAAAGTGGGGGGAGGCTCAGCGGAGCTTCCCC
CCTTTTGAGTATTGCCTTTA

Product: aminopeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MLNKQESQQRITRLQQELKAKGIDGALFIYPIDVYYFTGTRQNSTLWVPAEGKPRLMVRKSVSRAIKESCIEETVPFPSS
KEFPALFPPELQKIGFTFDVAPVQQYNYYAKLLPGREFVDVSAINREIRSVKSEWELGQMRKSGDMICQVFREVPGFLKE
GMREVDLAAEFECRLRKAGSEGYVRMRAFNQELFQGLAVSSAACDPGFFDGAVTGQGMSSASPHGASAAVIKANTPILVD
YTGIFNGYIVDITRFFVIGKLAPELEHGFATALAIQKYLVDNLKPGVICEELFLKAAEMAEEAGLGRNFMGAPGENAKFV
GHGVGLELDEFPVLAQGFKVPLRDGQTIAIEPKFVFPGQGVAGIENTFAVGKNGGVKLTDMPDEVVYL

Sequences:

>Translated_388_residues
MLNKQESQQRITRLQQELKAKGIDGALFIYPIDVYYFTGTRQNSTLWVPAEGKPRLMVRKSVSRAIKESCIEETVPFPSS
KEFPALFPPELQKIGFTFDVAPVQQYNYYAKLLPGREFVDVSAINREIRSVKSEWELGQMRKSGDMICQVFREVPGFLKE
GMREVDLAAEFECRLRKAGSEGYVRMRAFNQELFQGLAVSSAACDPGFFDGAVTGQGMSSASPHGASAAVIKANTPILVD
YTGIFNGYIVDITRFFVIGKLAPELEHGFATALAIQKYLVDNLKPGVICEELFLKAAEMAEEAGLGRNFMGAPGENAKFV
GHGVGLELDEFPVLAQGFKVPLRDGQTIAIEPKFVFPGQGVAGIENTFAVGKNGGVKLTDMPDEVVYL
>Mature_388_residues
MLNKQESQQRITRLQQELKAKGIDGALFIYPIDVYYFTGTRQNSTLWVPAEGKPRLMVRKSVSRAIKESCIEETVPFPSS
KEFPALFPPELQKIGFTFDVAPVQQYNYYAKLLPGREFVDVSAINREIRSVKSEWELGQMRKSGDMICQVFREVPGFLKE
GMREVDLAAEFECRLRKAGSEGYVRMRAFNQELFQGLAVSSAACDPGFFDGAVTGQGMSSASPHGASAAVIKANTPILVD
YTGIFNGYIVDITRFFVIGKLAPELEHGFATALAIQKYLVDNLKPGVICEELFLKAAEMAEEAGLGRNFMGAPGENAKFV
GHGVGLELDEFPVLAQGFKVPLRDGQTIAIEPKFVFPGQGVAGIENTFAVGKNGGVKLTDMPDEVVYL

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=308, Percent_Identity=25.974025974026, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 42680; Mature: 42680

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKQESQQRITRLQQELKAKGIDGALFIYPIDVYYFTGTRQNSTLWVPAEGKPRLMVRK
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCCEEEEECCCCCCCHHHH
SVSRAIKESCIEETVPFPSSKEFPALFPPELQKIGFTFDVAPVQQYNYYAKLLPGREFVD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCEEEECCHHHCCCCEEECCCCCEEE
VSAINREIRSVKSEWELGQMRKSGDMICQVFREVPGFLKEGMREVDLAAEFECRLRKAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EGYVRMRAFNQELFQGLAVSSAACDPGFFDGAVTGQGMSSASPHGASAAVIKANTPILVD
CCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEE
YTGIFNGYIVDITRFFVIGKLAPELEHGFATALAIQKYLVDNLKPGVICEELFLKAAEMA
ECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
EEAGLGRNFMGAPGENAKFVGHGVGLELDEFPVLAQGFKVPLRDGQTIAIEPKFVFPGQG
HHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHCCCEEECCCCCEEEEECEEECCCCC
VAGIENTFAVGKNGGVKLTDMPDEVVYL
CCCCCCCEEECCCCCEEEECCCCCEEEC
>Mature Secondary Structure
MLNKQESQQRITRLQQELKAKGIDGALFIYPIDVYYFTGTRQNSTLWVPAEGKPRLMVRK
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCCEEEEECCCCCCCHHHH
SVSRAIKESCIEETVPFPSSKEFPALFPPELQKIGFTFDVAPVQQYNYYAKLLPGREFVD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCEEEECCHHHCCCCEEECCCCCEEE
VSAINREIRSVKSEWELGQMRKSGDMICQVFREVPGFLKEGMREVDLAAEFECRLRKAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EGYVRMRAFNQELFQGLAVSSAACDPGFFDGAVTGQGMSSASPHGASAAVIKANTPILVD
CCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEE
YTGIFNGYIVDITRFFVIGKLAPELEHGFATALAIQKYLVDNLKPGVICEELFLKAAEMA
ECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
EEAGLGRNFMGAPGENAKFVGHGVGLELDEFPVLAQGFKVPLRDGQTIAIEPKFVFPGQG
HHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHCCCEEECCCCCEEEEECEEECCCCC
VAGIENTFAVGKNGGVKLTDMPDEVVYL
CCCCCCCEEECCCCCEEEECCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]