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The map label for this gene is etfA-7 [H]

Identifier: 197119202

GI number: 197119202

Start: 3254543

End: 3255460

Strand: Reverse

Name: etfA-7 [H]

Synonym: Gbem_2829

Alternate gene names: 197119202

Gene position: 3255460-3254543 (Counterclockwise)

Preceding gene: 197119203

Following gene: 197119201

Centisome position: 70.54

GC content: 64.27

Gene sequence:

>918_bases
ATGAAAGCGTTGCTTATCGCGGAATACAGGCAGGGGAAACTGCTGGAGACCACCTATGAACTGCAGGCCTTTGCCGGCCT
GTTAGGCGCCGAGAGCGCCATGGTGCTGGTGGGAAGCCCAGCCGATCTCCCGAAGTTCGCCGGCAAGCTATACCTGGCTG
ACGTAGCCAAGTACGGCGAGTACAACCCCGACCTGCACAAGAAGCTGGTGCTGGAGGCGGTCGCCAAGGAGAACCCCGAC
TACATCGTATTCGTGCACTCGTCCTACGGCTGGGACCTGGCGCCTCGCGTGGCCGCCGCTCTCCGCATCGGCCAGGTGTC
CGAGGTGGTGGGGCTTCCCGACGGAAAATTTGAAGTGACCTGCTGCAACGCCAAGCTGCGCCGGACCGTCGCCCCCAAGA
GCGCGCGGACCGTGGTCACCATCCAGGCCGGTGCCTTCTCCCCCCAGGGTGAGCCGCAGGGTGCGCCCCAGGTTGAGGGG
ATTGACGTGGCGGACCCAGCCGGAAAGACCGAATTCGTAGGGTATGAGGCTGCTGAGCAAAAGGACGTCGATCTCACCAG
GGCCGAGGTGATCGTCAGTGCCGGGCGCGGCGTGGGGAAGAAAGAGAACGTCCAGGTGATCGCGCAGCTTGCCAAGGCGC
TCGGTGGGGAACTGGGCGCGAGCCGTCCCGTCGTCGACGCAGGATGGGCGCCCCACAGCCACCAAGTCGGGACCACCGGC
CAGACCGTCAGCCCGAAGCTCTACGTCGCCTGCGGCATCAGCGGCGCGATTCAGCACCTGGCGGGGATGAAAATGGCGGA
CTTCATAGTCGCCATCAACAAGGACAAGGATGCGCCCATAGGCGAGATAGCCGACGTCCTGATCGTGGCAGACGTGTTGC
AGTTCGTGCCGGCGATGACGGCAAGGTGCGCCAGATGA

Upstream 100 bases:

>100_bases
ATCGTCATCGAGGGCGAGGTGAACGACCAGCTCGACAAACTGATGGGGATTCTCAAGGAAAAGACCACCGTGTTGCGTGC
GGCCTGAAAGGAGAACAGCT

Downstream 100 bases:

>100_bases
GCCTGACGGAAGGGAAGGTACAGGTCTACACCGGCAACGGCAAGGGAAAGACCACCGCCGCCTTGGGGCTGGCGCTCCGG
GCGGTCGGGCGGGGGCTCAA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKALLIAEYRQGKLLETTYELQAFAGLLGAESAMVLVGSPADLPKFAGKLYLADVAKYGEYNPDLHKKLVLEAVAKENPD
YIVFVHSSYGWDLAPRVAAALRIGQVSEVVGLPDGKFEVTCCNAKLRRTVAPKSARTVVTIQAGAFSPQGEPQGAPQVEG
IDVADPAGKTEFVGYEAAEQKDVDLTRAEVIVSAGRGVGKKENVQVIAQLAKALGGELGASRPVVDAGWAPHSHQVGTTG
QTVSPKLYVACGISGAIQHLAGMKMADFIVAINKDKDAPIGEIADVLIVADVLQFVPAMTARCAR

Sequences:

>Translated_305_residues
MKALLIAEYRQGKLLETTYELQAFAGLLGAESAMVLVGSPADLPKFAGKLYLADVAKYGEYNPDLHKKLVLEAVAKENPD
YIVFVHSSYGWDLAPRVAAALRIGQVSEVVGLPDGKFEVTCCNAKLRRTVAPKSARTVVTIQAGAFSPQGEPQGAPQVEG
IDVADPAGKTEFVGYEAAEQKDVDLTRAEVIVSAGRGVGKKENVQVIAQLAKALGGELGASRPVVDAGWAPHSHQVGTTG
QTVSPKLYVACGISGAIQHLAGMKMADFIVAINKDKDAPIGEIADVLIVADVLQFVPAMTARCAR
>Mature_305_residues
MKALLIAEYRQGKLLETTYELQAFAGLLGAESAMVLVGSPADLPKFAGKLYLADVAKYGEYNPDLHKKLVLEAVAKENPD
YIVFVHSSYGWDLAPRVAAALRIGQVSEVVGLPDGKFEVTCCNAKLRRTVAPKSARTVVTIQAGAFSPQGEPQGAPQVEG
IDVADPAGKTEFVGYEAAEQKDVDLTRAEVIVSAGRGVGKKENVQVIAQLAKALGGELGASRPVVDAGWAPHSHQVGTTG
QTVSPKLYVACGISGAIQHLAGMKMADFIVAINKDKDAPIGEIADVLIVADVLQFVPAMTARCAR

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=306, Percent_Identity=36.6013071895425, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI189181759, Length=263, Percent_Identity=38.4030418250951, Blast_Score=155, Evalue=4e-38,
Organism=Escherichia coli, GI1786226, Length=170, Percent_Identity=41.1764705882353, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787990, Length=124, Percent_Identity=39.5161290322581, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87082157, Length=217, Percent_Identity=29.4930875576037, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17506929, Length=307, Percent_Identity=36.4820846905537, Blast_Score=163, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6325261, Length=232, Percent_Identity=34.9137931034483, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136898, Length=308, Percent_Identity=36.6883116883117, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24652801, Length=308, Percent_Identity=36.6883116883117, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32164; Mature: 32164

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLIAEYRQGKLLETTYELQAFAGLLGAESAMVLVGSPADLPKFAGKLYLADVAKYGE
CCEEEEEECCCCCEEHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC
YNPDLHKKLVLEAVAKENPDYIVFVHSSYGWDLAPRVAAALRIGQVSEVVGLPDGKFEVT
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHCCCCCCEEEE
CCNAKLRRTVAPKSARTVVTIQAGAFSPQGEPQGAPQVEGIDVADPAGKTEFVGYEAAEQ
EECHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
KDVDLTRAEVIVSAGRGVGKKENVQVIAQLAKALGGELGASRPVVDAGWAPHSHQVGTTG
CCCCHHHHHHHEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCC
QTVSPKLYVACGISGAIQHLAGMKMADFIVAINKDKDAPIGEIADVLIVADVLQFVPAMT
CCCCCEEEEEECCHHHHHHHHCCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
ARCAR
HHCCC
>Mature Secondary Structure
MKALLIAEYRQGKLLETTYELQAFAGLLGAESAMVLVGSPADLPKFAGKLYLADVAKYGE
CCEEEEEECCCCCEEHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC
YNPDLHKKLVLEAVAKENPDYIVFVHSSYGWDLAPRVAAALRIGQVSEVVGLPDGKFEVT
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHCCCCCCEEEE
CCNAKLRRTVAPKSARTVVTIQAGAFSPQGEPQGAPQVEGIDVADPAGKTEFVGYEAAEQ
EECHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
KDVDLTRAEVIVSAGRGVGKKENVQVIAQLAKALGGELGASRPVVDAGWAPHSHQVGTTG
CCCCHHHHHHHEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCC
QTVSPKLYVACGISGAIQHLAGMKMADFIVAINKDKDAPIGEIADVLIVADVLQFVPAMT
CCCCCEEEEEECCHHHHHHHHCCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
ARCAR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]