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The map label for this gene is cobO-2 [H]

Identifier: 197119201

GI number: 197119201

Start: 3254016

End: 3254546

Strand: Reverse

Name: cobO-2 [H]

Synonym: Gbem_2828

Alternate gene names: 197119201

Gene position: 3254546-3254016 (Counterclockwise)

Preceding gene: 197119202

Following gene: 308535321

Centisome position: 70.52

GC content: 64.41

Gene sequence:

>531_bases
ATGAGCCTGACGGAAGGGAAGGTACAGGTCTACACCGGCAACGGCAAGGGAAAGACCACCGCCGCCTTGGGGCTGGCGCT
CCGGGCGGTCGGGCGGGGGCTCAAGGTCTGCATGGTCCAGTTCATCAAAGGGGGAGGGGAGTACGGCGAGCATATAGCCG
CCGAGCGGCTGGCGCCGCTGCTCACCATCCATCAGACCGGGCGGGACTGCTGGATCTATAAGGACCGGCTGGACCCGCAG
GACGTAGCCATAGCCCGGGGAACGCTGAACCTCGCTCGCGAGACCCTGACCGGCGGCGAATACGACCTGGTCATCCTTGA
CGAAATCAACGGTGCGGCCTGGTTCGGCCTCATCACCGTCGAGGACATTCTTGACCTCATCAAGCTAAGGCCCGAGCAGG
TGGAGCTGGTGCTGACGGGAAGAAGCGCCGACCCCCGGGTCATCGAGGCAGCTGACCTGGTCACCGAGATGGTCGAGGTG
AAGCATTACTACCAGGCAGGCGTGCCGGCCCGGACCGGGATCGAGAAGTGA

Upstream 100 bases:

>100_bases
TCAACAAGGACAAGGATGCGCCCATAGGCGAGATAGCCGACGTCCTGATCGTGGCAGACGTGTTGCAGTTCGTGCCGGCG
ATGACGGCAAGGTGCGCCAG

Downstream 100 bases:

>100_bases
TAGGGGGGCGGGGAGGGGGACAAAGAGCGGCTTTCCACGCAATTTTCACGATGAACCAGTGATAAAGGGGAGAAGGATGA
AAATGCTCGCGGGGATAAAG

Product: cob(I)yrinate a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MSLTEGKVQVYTGNGKGKTTAALGLALRAVGRGLKVCMVQFIKGGGEYGEHIAAERLAPLLTIHQTGRDCWIYKDRLDPQ
DVAIARGTLNLARETLTGGEYDLVILDEINGAAWFGLITVEDILDLIKLRPEQVELVLTGRSADPRVIEAADLVTEMVEV
KHYYQAGVPARTGIEK

Sequences:

>Translated_176_residues
MSLTEGKVQVYTGNGKGKTTAALGLALRAVGRGLKVCMVQFIKGGGEYGEHIAAERLAPLLTIHQTGRDCWIYKDRLDPQ
DVAIARGTLNLARETLTGGEYDLVILDEINGAAWFGLITVEDILDLIKLRPEQVELVLTGRSADPRVIEAADLVTEMVEV
KHYYQAGVPARTGIEK
>Mature_175_residues
SLTEGKVQVYTGNGKGKTTAALGLALRAVGRGLKVCMVQFIKGGGEYGEHIAAERLAPLLTIHQTGRDCWIYKDRLDPQD
VAIARGTLNLARETLTGGEYDLVILDEINGAAWFGLITVEDILDLIKLRPEQVELVLTGRSADPRVIEAADLVTEMVEVK
HYYQAGVPARTGIEK

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=170, Percent_Identity=38.8235294117647, Blast_Score=109, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19161; Mature: 19030

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTEGKVQVYTGNGKGKTTAALGLALRAVGRGLKVCMVQFIKGGGEYGEHIAAERLAPL
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
LTIHQTGRDCWIYKDRLDPQDVAIARGTLNLARETLTGGEYDLVILDEINGAAWFGLITV
HEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEH
EDILDLIKLRPEQVELVLTGRSADPRVIEAADLVTEMVEVKHYYQAGVPARTGIEK
HHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SLTEGKVQVYTGNGKGKTTAALGLALRAVGRGLKVCMVQFIKGGGEYGEHIAAERLAPL
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
LTIHQTGRDCWIYKDRLDPQDVAIARGTLNLARETLTGGEYDLVILDEINGAAWFGLITV
HEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEH
EDILDLIKLRPEQVELVLTGRSADPRVIEAADLVTEMVEVKHYYQAGVPARTGIEK
HHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]