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The map label for this gene is helD [H]

Identifier: 197119045

GI number: 197119045

Start: 3087270

End: 3089159

Strand: Reverse

Name: helD [H]

Synonym: Gbem_2668

Alternate gene names: 197119045

Gene position: 3089159-3087270 (Counterclockwise)

Preceding gene: 197119046

Following gene: 197119044

Centisome position: 66.94

GC content: 59.47

Gene sequence:

>1890_bases
ATGGAAATTGTGCAACAGGAAGTGAAGCGGCTGGACGGGATTCATGAGGCAATAGAGCGGTACGCGGTCGACCGCCTGCG
GACGATAGCGAAGCACGAAGCATATACGAAGGAACTGGAACAGGAGCGCCTTAACGCGGTGGGGTGGCACGAGAAGAACG
ACCTCACCGAGAAGCTGGTTGAGCACGGCCACCACTCTCCACGCAAATACCTTCACGAATACACACAGCAAGCCTCCCCT
TACTTCGGCATTCTCGGCATCCACGACAACGATCGAAGGATCGGCAGAAAAGAATACCTGATCGGCAACCAGACGCTCAT
GGACGGTCAGCGGGTCGCCATCGTCGACTGGAGAAAGGCCGAGATCACCGGCCCCTTCTACGAGGGTTATGACGTGGGCG
AGGAGTACGAACTCACCATCAGAGGTGTCGAGAGGGAAGGGGTGATCACCCGCAGGGACAAGGTGACCATAAACAGGAAG
GCCCTGAACCGGATCGAGACACCTTCGGAGGTGTACGAGCTGCGCGGCGGGGAGTGGCATAACAACGGATCGGCCTGCGA
GACGAGCGCGGATACGAAGGAGCGGACCGAGGACCACCGGATGGTGGATTCGATTGCGTCCCTGATCTCCCCGGAGCAGT
TCCGGGCTATTACCAAGCAGAGGGAAGGGGTGGTGGTGATAAACGGAGCGGCCGGCGCGGGGAAGACCACTGTGGCGCTG
CACCGGCTTTCCTTTCTCATGTTCGACGCGCCGGAGAAGTACCGCCCGGAGCGCTGCGTCGTTCTCATGTTCAACCGGGT
GCTGCGCGACTACGTGAAGCAGAGCAGCGATACCCTTCTTGGACCGGTCCGGGTGGATACCTACAGCGCCTGGTCGCTGA
CGGCCCTTGCCGCTCTGGGTGTCCACTCGCTCAAAACGAGTTTCGACGACCCCTTTGGCGCGCAGAAGAAAAGCAGCATG
ATGCCGGCCATGCTGGCCAAGTACGTGAAGGAGACGGCAAAGATAGAACCAGTCACCGATCTTTGGCGTTTCCTGATGCA
GGAGTACGTGGTTGCCGCGCTGTTTCCTGATTCAGGGGAGGCGTTCCAGCAGGAGGCCCAAAGGAAGTTCGAAGCAAAGG
AGCGGGTGCTCTCTTTCTCGGATATCAGCATCCTGCTGCGTCTGGCACAACTGCGGCGACCTGCCGGGACCGTCGTCCTG
GGGGCGCTGAACGCCTACGACCACATCGTGGTCGATGAGGCGCAGGACCTCTCCTCGCTCGAACTGCGTACCATCGTGGC
CGCTACTTCCCCTGCGCGCAGCATCACCATATGTGCCGACGAGAAACAGCAGATCCTCAGCTTCCTCGATTCCCAAGGGT
TTTCGAGCGTCATGGCCCAGCTCCACTCGCAGGGGCTCGAAAAGGAGAACCTGACGGTTTCTTACCGTTGCCCCAAGGAA
ATCGTCGATCTCGCTGCCCAGGTCAGCGGCAGGAAGGTCGATACTTCGAAGGCTCACACCGGCGTGGTTGAGTTTCACGC
GACTAAGAACGCCGCGGAGTCGATGGCGAAGATCCGGCAGATCGTTGAAGGACTAGTACAGGCTGCTCCGGGCTCTCTTG
CCGGCGTAATTTGCAAGAAGAAAGCAGACGTAAAGGCACTTCATGCCGCGCTTGCCGGCGTCCAAGGGCTGCACCCGGAG
GGGGAGATATCCTTTTCGCCCGGCGTCCAGGTGATTCATGCTCATGCGATAAAGGGGGTCGAGTTCTCCCACGTCATCCT
CTACAACCCCAGCTCGTACGACTACCGCCAGACGGAGCCGGATAGGAACCTGCTTTACGTGGCGATTACACGCGCTTGCA
AGACCCTGCACATCGTTCACCATCAGGCGTTGGCGAAGGGGCTTGGTTGA

Upstream 100 bases:

>100_bases
AAGGATTGATGTCCGCCGCGAGATCTGACAAAATGCCGACCTTTCGAAAAGTAACGGCTGCGACGTATGCCGTCTGAGAC
ACGCTGCTGGTGGAGATTTG

Downstream 100 bases:

>100_bases
AAGGAAGCAAAAGGGATCAAAAAACCTTCCCTCACCCGCCCTTCGGGCACCCTCTCCCATCTCAAGCTCCAGCTTGGGAA
CCCAAGGATGCAAGCTTCAA

Product: helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MEIVQQEVKRLDGIHEAIERYAVDRLRTIAKHEAYTKELEQERLNAVGWHEKNDLTEKLVEHGHHSPRKYLHEYTQQASP
YFGILGIHDNDRRIGRKEYLIGNQTLMDGQRVAIVDWRKAEITGPFYEGYDVGEEYELTIRGVEREGVITRRDKVTINRK
ALNRIETPSEVYELRGGEWHNNGSACETSADTKERTEDHRMVDSIASLISPEQFRAITKQREGVVVINGAAGAGKTTVAL
HRLSFLMFDAPEKYRPERCVVLMFNRVLRDYVKQSSDTLLGPVRVDTYSAWSLTALAALGVHSLKTSFDDPFGAQKKSSM
MPAMLAKYVKETAKIEPVTDLWRFLMQEYVVAALFPDSGEAFQQEAQRKFEAKERVLSFSDISILLRLAQLRRPAGTVVL
GALNAYDHIVVDEAQDLSSLELRTIVAATSPARSITICADEKQQILSFLDSQGFSSVMAQLHSQGLEKENLTVSYRCPKE
IVDLAAQVSGRKVDTSKAHTGVVEFHATKNAAESMAKIRQIVEGLVQAAPGSLAGVICKKKADVKALHAALAGVQGLHPE
GEISFSPGVQVIHAHAIKGVEFSHVILYNPSSYDYRQTEPDRNLLYVAITRACKTLHIVHHQALAKGLG

Sequences:

>Translated_629_residues
MEIVQQEVKRLDGIHEAIERYAVDRLRTIAKHEAYTKELEQERLNAVGWHEKNDLTEKLVEHGHHSPRKYLHEYTQQASP
YFGILGIHDNDRRIGRKEYLIGNQTLMDGQRVAIVDWRKAEITGPFYEGYDVGEEYELTIRGVEREGVITRRDKVTINRK
ALNRIETPSEVYELRGGEWHNNGSACETSADTKERTEDHRMVDSIASLISPEQFRAITKQREGVVVINGAAGAGKTTVAL
HRLSFLMFDAPEKYRPERCVVLMFNRVLRDYVKQSSDTLLGPVRVDTYSAWSLTALAALGVHSLKTSFDDPFGAQKKSSM
MPAMLAKYVKETAKIEPVTDLWRFLMQEYVVAALFPDSGEAFQQEAQRKFEAKERVLSFSDISILLRLAQLRRPAGTVVL
GALNAYDHIVVDEAQDLSSLELRTIVAATSPARSITICADEKQQILSFLDSQGFSSVMAQLHSQGLEKENLTVSYRCPKE
IVDLAAQVSGRKVDTSKAHTGVVEFHATKNAAESMAKIRQIVEGLVQAAPGSLAGVICKKKADVKALHAALAGVQGLHPE
GEISFSPGVQVIHAHAIKGVEFSHVILYNPSSYDYRQTEPDRNLLYVAITRACKTLHIVHHQALAKGLG
>Mature_629_residues
MEIVQQEVKRLDGIHEAIERYAVDRLRTIAKHEAYTKELEQERLNAVGWHEKNDLTEKLVEHGHHSPRKYLHEYTQQASP
YFGILGIHDNDRRIGRKEYLIGNQTLMDGQRVAIVDWRKAEITGPFYEGYDVGEEYELTIRGVEREGVITRRDKVTINRK
ALNRIETPSEVYELRGGEWHNNGSACETSADTKERTEDHRMVDSIASLISPEQFRAITKQREGVVVINGAAGAGKTTVAL
HRLSFLMFDAPEKYRPERCVVLMFNRVLRDYVKQSSDTLLGPVRVDTYSAWSLTALAALGVHSLKTSFDDPFGAQKKSSM
MPAMLAKYVKETAKIEPVTDLWRFLMQEYVVAALFPDSGEAFQQEAQRKFEAKERVLSFSDISILLRLAQLRRPAGTVVL
GALNAYDHIVVDEAQDLSSLELRTIVAATSPARSITICADEKQQILSFLDSQGFSSVMAQLHSQGLEKENLTVSYRCPKE
IVDLAAQVSGRKVDTSKAHTGVVEFHATKNAAESMAKIRQIVEGLVQAAPGSLAGVICKKKADVKALHAALAGVQGLHPE
GEISFSPGVQVIHAHAIKGVEFSHVILYNPSSYDYRQTEPDRNLLYVAITRACKTLHIVHHQALAKGLG

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 70278; Mature: 70278

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIVQQEVKRLDGIHEAIERYAVDRLRTIAKHEAYTKELEQERLNAVGWHEKNDLTEKLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EHGHHSPRKYLHEYTQQASPYFGILGIHDNDRRIGRKEYLIGNQTLMDGQRVAIVDWRKA
HCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHEEECCCEEECCCEEEEEECCHH
EITGPFYEGYDVGEEYELTIRGVEREGVITRRDKVTINRKALNRIETPSEVYELRGGEWH
CCCCCCCCCCCCCCCEEEEEEECCCCCCEEECCCEEECHHHHHHCCCHHHHHHCCCCCCC
NNGSACETSADTKERTEDHRMVDSIASLISPEQFRAITKQREGVVVINGAAGAGKTTVAL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEECCCCCCHHHHHH
HRLSFLMFDAPEKYRPERCVVLMFNRVLRDYVKQSSDTLLGPVRVDTYSAWSLTALAALG
HHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCEECCEEECCCCHHHHHHHHHHH
VHSLKTSFDDPFGAQKKSSMMPAMLAKYVKETAKIEPVTDLWRFLMQEYVVAALFPDSGE
HHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCH
AFQQEAQRKFEAKERVLSFSDISILLRLAQLRRPAGTVVLGALNAYDHIVVDEAQDLSSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCCHHH
ELRTIVAATSPARSITICADEKQQILSFLDSQGFSSVMAQLHSQGLEKENLTVSYRCPKE
HHHHHEEECCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCHH
IVDLAAQVSGRKVDTSKAHTGVVEFHATKNAAESMAKIRQIVEGLVQAAPGSLAGVICKK
HHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
KADVKALHAALAGVQGLHPEGEISFSPGVQVIHAHAIKGVEFSHVILYNPSSYDYRQTEP
CCHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEHHHHCCCCEEEEEEECCCCCCCCCCCC
DRNLLYVAITRACKTLHIVHHQALAKGLG
CCCEEEEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIVQQEVKRLDGIHEAIERYAVDRLRTIAKHEAYTKELEQERLNAVGWHEKNDLTEKLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EHGHHSPRKYLHEYTQQASPYFGILGIHDNDRRIGRKEYLIGNQTLMDGQRVAIVDWRKA
HCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHEEECCCEEECCCEEEEEECCHH
EITGPFYEGYDVGEEYELTIRGVEREGVITRRDKVTINRKALNRIETPSEVYELRGGEWH
CCCCCCCCCCCCCCCEEEEEEECCCCCCEEECCCEEECHHHHHHCCCHHHHHHCCCCCCC
NNGSACETSADTKERTEDHRMVDSIASLISPEQFRAITKQREGVVVINGAAGAGKTTVAL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEECCCCCCHHHHHH
HRLSFLMFDAPEKYRPERCVVLMFNRVLRDYVKQSSDTLLGPVRVDTYSAWSLTALAALG
HHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCEECCEEECCCCHHHHHHHHHHH
VHSLKTSFDDPFGAQKKSSMMPAMLAKYVKETAKIEPVTDLWRFLMQEYVVAALFPDSGE
HHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCH
AFQQEAQRKFEAKERVLSFSDISILLRLAQLRRPAGTVVLGALNAYDHIVVDEAQDLSSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCCHHH
ELRTIVAATSPARSITICADEKQQILSFLDSQGFSSVMAQLHSQGLEKENLTVSYRCPKE
HHHHHEEECCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCHH
IVDLAAQVSGRKVDTSKAHTGVVEFHATKNAAESMAKIRQIVEGLVQAAPGSLAGVICKK
HHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
KADVKALHAALAGVQGLHPEGEISFSPGVQVIHAHAIKGVEFSHVILYNPSSYDYRQTEP
CCHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEHHHHCCCCEEEEEEECCCCCCCCCCCC
DRNLLYVAITRACKTLHIVHHQALAKGLG
CCCEEEEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]