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The map label for this gene is 197119023

Identifier: 197119023

GI number: 197119023

Start: 3063968

End: 3065524

Strand: Direct

Name: 197119023

Synonym: Gbem_2646

Alternate gene names: NA

Gene position: 3063968-3065524 (Clockwise)

Preceding gene: 197119008

Following gene: 197119024

Centisome position: 66.39

GC content: 63.78

Gene sequence:

>1557_bases
ATGGTTCGAAAGCTTATAAAATCGCTACTTGAAGCAAAGGCTTACCCCGAGCCCACGGCCGGGGTGCGCCTCATCGAGAC
CCACGTTTCATTCATCTTCGTTACCGACTCCTTCGTATACAAGGTCAAAAAGTCCGTCGATTACGGTTTTCTCGACTTCA
CCACGCTGGAGCGCCGGCGCTTTTACTGCGAGGAAGAGGTGCGGTTGAACCGGCGCCTCTGCCCGGACCTCTACCTGGGG
GTGGTGGAACTGCGGCGCAATTCCCAAGGAGCGTCCTTTGCCGGCGGGGGCGAGCTCCTTGACTACGCGGTGAAGATGAA
ACGGCTCCCCGAAGAGCGGATGCTGGTGCACCTTCTGGAACGGGGGGAAGCGGGCGTCGCCGACATGGACCGGATCGCCC
GGGTGGTGGCCGATTTCCATGCCAAGGCATTACGCAGCGCACAGATAGACGCCTGCGGCCAAACCGCCGTCATCCGCCGC
AACTGGGAGGAGAACTTCCGGCAGGCGGCACCATTCGCGGGGGTGACCATATCCGCCTGCGAACTTGCGGACATACGGCG
CTGGGCCGAGCGGTTCCTGGAGCAAAACGAGGAGCAATTCCGTCTGCGGGTGGCCAAAGGGTACATCAGGGAGTGCGACG
GCGACCTCCACTCCGGCAACATCTGCCTCACCGACAAAGTCTGCATCTTCGACTGCATCGAGTTCAACGAGCGGTTTCGC
TACATAGACACCGCGGCGGACCTCTCGTTCCTGCTGATGGACCTGGAGTACGCCGGGCGCCCGGACCTGTCGGAGGCGCT
CCTGTCGGCCTACCAAAAGGCCGCTGGGGATCGGGAAATAGGGAACCTGCTTCCGTTCTACAAGACCTACCGTGCCTTCG
TGCGCGGCAAGGTGACCAGCTTTCTGCTGAACGACCCCGACTTACCCTCCACGGAACTTGCCGTCAAAAGGGAGACGGCC
CGGCGTTATTTCCGCCTGGCCCGCGGCTATACGCTGAGGGACCGGCTCAAACCTTCCCTGGTGATCACCTGCGGCCTCAT
GGGAAGCGGCAAGAGCACCCTGGCCCGGGAACTCGCCCTGGAACTCGGGTTCCAGTTGCGGCGCTCGGACGTGCTGCGCA
AGGAAGTAGCCGGCCTTCCGCTGCAGCCGGTGGCGGAAGAGTACCGGGGGGGCATCTACAATGCCGATATGGACCGCGCC
ACTTACGCAGCTCTTTTAGCCGAGGCCGAAGAGGCGCTCAAGGCGGGCAAGGGGGTGGTGGCCGACGCCACATTCCGCCG
CGCCGCCGACCGGGAGGCCTTCCGGGCCTTGGCCGCGCAGCTTGGCGTTCCCTGCTACACGGTCGAGACCCGCTGCCCCG
AACTTATAATCCGGCAGCGGCTGGAGGCGCGCCGCGGCGACGCAAGCGAAGTCTCAGACGCCAGGTGGGAGCACTTCCAC
CGGCAACAGGCGGAGTTCGAGGCGCCGCAAGCGGGAGAGTCCATCCCGGTCGACTCCACCCTCCCCCTCTCCACCGAGGC
TGACCTGGTGTTGCGCGCAATGGGGTTACTGCCATGA

Upstream 100 bases:

>100_bases
GTAAAAGCGTCAAACAACAATTGCTGTATTTTATGCTATTGCGCCTGAAATGCTCTATGATAGTATTCTGTAGTCAAATC
ATCGGTTTAACGGCAAAAGC

Downstream 100 bases:

>100_bases
AGACGACCATCAGGGAGCTGCTCGTTAAAAGGCTCAAGCTGAAGGACACCTGGGTGATCTGCTTCGTCCTCGGCATGATC
ATGATGAACTACCCGTTCAT

Product: kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MVRKLIKSLLEAKAYPEPTAGVRLIETHVSFIFVTDSFVYKVKKSVDYGFLDFTTLERRRFYCEEEVRLNRRLCPDLYLG
VVELRRNSQGASFAGGGELLDYAVKMKRLPEERMLVHLLERGEAGVADMDRIARVVADFHAKALRSAQIDACGQTAVIRR
NWEENFRQAAPFAGVTISACELADIRRWAERFLEQNEEQFRLRVAKGYIRECDGDLHSGNICLTDKVCIFDCIEFNERFR
YIDTAADLSFLLMDLEYAGRPDLSEALLSAYQKAAGDREIGNLLPFYKTYRAFVRGKVTSFLLNDPDLPSTELAVKRETA
RRYFRLARGYTLRDRLKPSLVITCGLMGSGKSTLARELALELGFQLRRSDVLRKEVAGLPLQPVAEEYRGGIYNADMDRA
TYAALLAEAEEALKAGKGVVADATFRRAADREAFRALAAQLGVPCYTVETRCPELIIRQRLEARRGDASEVSDARWEHFH
RQQAEFEAPQAGESIPVDSTLPLSTEADLVLRAMGLLP

Sequences:

>Translated_518_residues
MVRKLIKSLLEAKAYPEPTAGVRLIETHVSFIFVTDSFVYKVKKSVDYGFLDFTTLERRRFYCEEEVRLNRRLCPDLYLG
VVELRRNSQGASFAGGGELLDYAVKMKRLPEERMLVHLLERGEAGVADMDRIARVVADFHAKALRSAQIDACGQTAVIRR
NWEENFRQAAPFAGVTISACELADIRRWAERFLEQNEEQFRLRVAKGYIRECDGDLHSGNICLTDKVCIFDCIEFNERFR
YIDTAADLSFLLMDLEYAGRPDLSEALLSAYQKAAGDREIGNLLPFYKTYRAFVRGKVTSFLLNDPDLPSTELAVKRETA
RRYFRLARGYTLRDRLKPSLVITCGLMGSGKSTLARELALELGFQLRRSDVLRKEVAGLPLQPVAEEYRGGIYNADMDRA
TYAALLAEAEEALKAGKGVVADATFRRAADREAFRALAAQLGVPCYTVETRCPELIIRQRLEARRGDASEVSDARWEHFH
RQQAEFEAPQAGESIPVDSTLPLSTEADLVLRAMGLLP
>Mature_518_residues
MVRKLIKSLLEAKAYPEPTAGVRLIETHVSFIFVTDSFVYKVKKSVDYGFLDFTTLERRRFYCEEEVRLNRRLCPDLYLG
VVELRRNSQGASFAGGGELLDYAVKMKRLPEERMLVHLLERGEAGVADMDRIARVVADFHAKALRSAQIDACGQTAVIRR
NWEENFRQAAPFAGVTISACELADIRRWAERFLEQNEEQFRLRVAKGYIRECDGDLHSGNICLTDKVCIFDCIEFNERFR
YIDTAADLSFLLMDLEYAGRPDLSEALLSAYQKAAGDREIGNLLPFYKTYRAFVRGKVTSFLLNDPDLPSTELAVKRETA
RRYFRLARGYTLRDRLKPSLVITCGLMGSGKSTLARELALELGFQLRRSDVLRKEVAGLPLQPVAEEYRGGIYNADMDRA
TYAALLAEAEEALKAGKGVVADATFRRAADREAFRALAAQLGVPCYTVETRCPELIIRQRLEARRGDASEVSDARWEHFH
RQQAEFEAPQAGESIPVDSTLPLSTEADLVLRAMGLLP

Specific function: Some isolated peptides of this protein are able to bind to human U937 monocytoblastic and A549 epithelial cell lines [H]

COG id: COG2187

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR010488 [H]

Pfam domain/function: PF06414 Zeta_toxin [H]

EC number: NA

Molecular weight: Translated: 58527; Mature: 58527

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRKLIKSLLEAKAYPEPTAGVRLIETHVSFIFVTDSFVYKVKKSVDYGFLDFTTLERRR
CHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEEEHHHHHHHHHHCCCCCEEHHHHHHHH
FYCEEEVRLNRRLCPDLYLGVVELRRNSQGASFAGGGELLDYAVKMKRLPEERMLVHLLE
HHCHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
RGEAGVADMDRIARVVADFHAKALRSAQIDACGQTAVIRRNWEENFRQAAPFAGVTISAC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHCCCCCCEEHHH
ELADIRRWAERFLEQNEEQFRLRVAKGYIRECDGDLHSGNICLTDKVCIFDCIEFNERFR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHH
YIDTAADLSFLLMDLEYAGRPDLSEALLSAYQKAAGDREIGNLLPFYKTYRAFVRGKVTS
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
FLLNDPDLPSTELAVKRETARRYFRLARGYTLRDRLKPSLVITCGLMGSGKSTLARELAL
HEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHH
ELGFQLRRSDVLRKEVAGLPLQPVAEEYRGGIYNADMDRATYAALLAEAEEALKAGKGVV
HHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCE
ADATFRRAADREAFRALAAQLGVPCYTVETRCPELIIRQRLEARRGDASEVSDARWEHFH
EHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RQQAEFEAPQAGESIPVDSTLPLSTEADLVLRAMGLLP
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MVRKLIKSLLEAKAYPEPTAGVRLIETHVSFIFVTDSFVYKVKKSVDYGFLDFTTLERRR
CHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEEEHHHHHHHHHHCCCCCEEHHHHHHHH
FYCEEEVRLNRRLCPDLYLGVVELRRNSQGASFAGGGELLDYAVKMKRLPEERMLVHLLE
HHCHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
RGEAGVADMDRIARVVADFHAKALRSAQIDACGQTAVIRRNWEENFRQAAPFAGVTISAC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHCCCCCCEEHHH
ELADIRRWAERFLEQNEEQFRLRVAKGYIRECDGDLHSGNICLTDKVCIFDCIEFNERFR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHH
YIDTAADLSFLLMDLEYAGRPDLSEALLSAYQKAAGDREIGNLLPFYKTYRAFVRGKVTS
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
FLLNDPDLPSTELAVKRETARRYFRLARGYTLRDRLKPSLVITCGLMGSGKSTLARELAL
HEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHH
ELGFQLRRSDVLRKEVAGLPLQPVAEEYRGGIYNADMDRATYAALLAEAEEALKAGKGVV
HHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCE
ADATFRRAADREAFRALAAQLGVPCYTVETRCPELIIRQRLEARRGDASEVSDARWEHFH
EHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RQQAEFEAPQAGESIPVDSTLPLSTEADLVLRAMGLLP
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]