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The map label for this gene is ppiC [H]

Identifier: 197119010

GI number: 197119010

Start: 3049442

End: 3049723

Strand: Reverse

Name: ppiC [H]

Synonym: Gbem_2633

Alternate gene names: 197119010

Gene position: 3049723-3049442 (Counterclockwise)

Preceding gene: 197119011

Following gene: 197119009

Centisome position: 66.08

GC content: 59.57

Gene sequence:

>282_bases
ATGACAAAAGCTAGTGCGCGTCACATTTTAGTAGCTACCGAACAGGAGTGCGTAGCGCTCAAGACCAAGATAGAATCGGG
AGCCGATTTCGGCGACTGCGCCCGCGAGAGTTCCCTTTGCCCCTCGGGGAATCAGGGTGGGCGTCTGGGCGAGTTCCGCC
CGGGGCAGATGGTGAGGGAATTCGACGAAGTGGTTTTCAGCGGCGAAGTCGGCAAGGTCCTCGGGCCGGTCAAGACCCAG
TTCGGCTACCACCTGATCGAGATCATGAGCCGCACCGCCTAA

Upstream 100 bases:

>100_bases
ATCCTGGTGGGACTGGACCGCGCCGTGCGCGACATGTCCGAGCTGGTGAGATACGCCTGAGCTTCAGGCGGGAAGAAAGC
ATCGAACAAAGGAGAAGCAG

Downstream 100 bases:

>100_bases
GGGTAGCTTTCACAGGCATCAAGGTAAAAGGGGAACCGATGGCAGAAACTCAGGAGAAACAGTCAGTAGTAGATCTCATC
TTCAGCGCACCCTTTTTGCT

Product: PpiC-type peptidylprolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase C; Parvulin; Rotamase C [H]

Number of amino acids: Translated: 93; Mature: 92

Protein sequence:

>93_residues
MTKASARHILVATEQECVALKTKIESGADFGDCARESSLCPSGNQGGRLGEFRPGQMVREFDEVVFSGEVGKVLGPVKTQ
FGYHLIEIMSRTA

Sequences:

>Translated_93_residues
MTKASARHILVATEQECVALKTKIESGADFGDCARESSLCPSGNQGGRLGEFRPGQMVREFDEVVFSGEVGKVLGPVKTQ
FGYHLIEIMSRTA
>Mature_92_residues
TKASARHILVATEQECVALKTKIESGADFGDCARESSLCPSGNQGGRLGEFRPGQMVREFDEVVFSGEVGKVLGPVKTQF
GYHLIEIMSRTA

Specific function: PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=89, Percent_Identity=53.9325842696629, Blast_Score=101, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 10063; Mature: 9931

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKASARHILVATEQECVALKTKIESGADFGDCARESSLCPSGNQGGRLGEFRPGQMVRE
CCCCCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
FDEVVFSGEVGKVLGPVKTQFGYHLIEIMSRTA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKASARHILVATEQECVALKTKIESGADFGDCARESSLCPSGNQGGRLGEFRPGQMVRE
CCCCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
FDEVVFSGEVGKVLGPVKTQFGYHLIEIMSRTA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]