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The map label for this gene is gacS [H]

Identifier: 197118872

GI number: 197118872

Start: 2890614

End: 2894702

Strand: Reverse

Name: gacS [H]

Synonym: Gbem_2495

Alternate gene names: 197118872

Gene position: 2894702-2890614 (Counterclockwise)

Preceding gene: 197118873

Following gene: 197118871

Centisome position: 62.72

GC content: 64.59

Gene sequence:

>4089_bases
ATGAAGAAATTGATTAAATTGCCGACGCTCAGGGCGCGGCTTGCCTTCTGGTTCACGGCGATCTGCCTCGTGCCTTTGTT
CCTGGTCACCACCATCATCTACATGCAGCGGGTCAAGTTGGCGCGGTCGCTGATGTTCGACAAGCTGAACGCGGTGACCT
CGCTGCGCCAGCAGCAGATCGGCAGCATCCTCGACAACATGATCGTGGACGCCTCCACCATCGCCTCCGACCACTCGGTG
CTGGAAACGGCAGAGCAGCTTCTGAGCGGGGCCGGCGGGGGGCGCGTTACCAGCGAGAGCCTGACCCTGCTTCGGGGGTA
TCAGAGCAGCAACGCCTCCGTAACCGACGTCTCCATAGTTTCACACGACGGCACCGTCGTGCTTTGCACCAGTGACAGCA
GGATCGGGACGCGCGTGGCGCGGCCCGAGATGGTGGGCAACGCGCTGCAGGATCTGGCGCCCACCTTCGGAGACGCCTAC
CTGGGGAGCGACGGCATCCCCAGCATCGACGTCGCCGTCCCGATCGGGGCGGCGACCAAATCGCGCGTCGGCGCCCTCCT
GGTAGCGCGCTACAACCTGCACACCCTGCTTTACGACATCACCGGCAACCGCACCGGCATGGGGGATACCGGCGAGACGG
TGCTGGTGAACCGGGAGGTGATGCCTCTCAACGAGCTGCGGGCCTTCTCCCAGGGGATACTGAAGGTGCCGCTCAAGGGG
AAACCGGCGCAGATGGCGGCGCGGGGAGAAAGCGGCATCGCGCAGACCACCGACTATCGCGGAGTGGATGTGCTGTCCGC
CTTTGTCCACATACCCCGCACCGGCTGGGGGCTCGTCTGCAAGCAGGACAGCCGCGAGATCCTGGCGCCGATCCGTAGCC
TCCTCTTCATAACCTATGGTCTCGCTGCGCTCATCTCGGTTTTTGCCTGCTTGCTCGCCTTCAGGCTGGCGCGATCCATA
GCCGATCCGCTGGTGAACCTGGCTGCCAGCGCGAAGGAGCTGGAAGATGGTGATTTCGACGCCCGGGCCGTCCCGGAGGG
TACCGACGAACAGAAGACCCTGGCGCGAAGTTTCAACAGCATGGCCCGGACGCTGCAGACGAAGATGGCGGCCCAGCAAG
GGATGTCGCGGCTCTCCCAGAACCTGGTAGTGGCCGAGGGGATGGACGACTTTTTCAGCAAGCTCCTCCCGGTCTTTTTG
GAGATCACCGGCGCCAGGATGGCGGTCGCCTACGTGGAGGAGCGGCAGACAGGGGAGTTTGCGCCCATGCATGCCATAGG
TCTCGATTCTTCCCTGCTGCGCCGGTTCCAACGCAGGCATCTGGAGGGAGAGTTGGGGGTGATCCTCGCCAGCGGCACCG
TGTCCTGCTATACGCCGCAGGAAGGGAGCCCGCTGCGCTTTGCCACCAGCTTCGGCGAGATCGTTCCCGCCGAGATAGCC
ACCGTCCCGATCTCGGTCGACGCCGAGATCCGCGCTTTCGTTTCCATCGCCTCGGAGCGCCCCTTCCCGCCGAAGGTGCA
CGAGATCCTGGAGCTGGTGCAGATGCCGCTGGGGGCGGCCTTCGCCAGGATACTCTCCGGCGAGGATGTCCGGTTGCTGG
CGAACGAACTGGCGCTTAAAAACGAGGAGCTGACCCAGCAGTCCGAGGAACTGGTGCAGCAGTCCACCGAGCTGGCCCAC
CAGTCGGAGGAGCTTTCCCGCCACAACCAGGTGCTGGACCTGCAAAAGCAGCAATTGGAAGAGGCGACCAGGCTCAAGAG
CGAATTCCTCTCCAACATGAGCCATGAGCTCAGAACCCCGCTCAACTCGGTGCTGGCGCTCTCCCGGGTGCTGGCGGTGC
AGGGAGGCTCGCGTCTCACCGAGGACGAGAAGGGGTACCTTTCCATCATCGAGAGAAACGGCAAGCACCTTTTGTCCCTG
ATCAACGACATCCTCGACCTGGCCAAGATCGAGTCCGGCCGCCAGGAGGTTTACCTGGAGACGGTCTCCCTGCAAAAGGT
CACAGCCGAAGTGGTGGACGGGCTTTCGGTGCTGGCCCGCGAAAAGGGGATTGCTATCTCGCTGGAGGCGCCCGAGGCGC
TCCCAACCGCGGTGATCGACGTGAAAAGGCTGCGCCAGATGCTGCAGAACCTGATCGGCAACGCGGTGAAGTTCACCGCC
GAGGGGGCGGTCACGGTGAGGCTCGGCGCCGAGGGGGAAGAGTTCCTGGTCGAGGTGGAGGATACCGGCATCGGCATAGC
GCCGCAGTACCTGGAAACCATTTTCCACGAATTCCGCCAGGCCGACGGCAGCACCTCCCGCTCCTTCGAGGGGACGGGGC
TTGGGCTTGCCATCGTGAAGAAGACGGCGCGCCTTTTGGGAGGGGACGTGTCGGTGCGAAGCGAGCTCGGCAAGGGGTCC
GTCTTCACCCTGCGGCTTCCTTGCGACGGCACCGGGAGCGTGCAGGGACCGCAGGCTTCGGGTAACGCCTCCTTCCCTGC
GGAGCGGGCGCAGGCTCCGATGCAGGGTAGGTCGGTCCTGGTGGTGGACGACGACCCCGAGGCCGTGTCGCTGATCGCGT
CGCATCTCTCTCAGGCGGGTTTCGAAACGCTTACCGCGCTAAACGGCGCCGACGCCCTGAGGCTCGCACGCGCCAAGAAG
CCTTTCGCCATCACGCTCGACATCATGATGCCGGACATGGACGGTTGGGAGGTGATGCGCGAGCTGAAGGACCAGCGCGA
AACGGCCGATATCCCCGTGGTGATCGTGTCGCTGTCGGACGACCGCGCGACGGGAATCGCCCTCGGCGCGGTCGGGGTGA
TAGCCAAACCGGTGAGCAGGGAACAGCTCATAGAGACCTTCACCAAGCTCGCCGGCGCGGGATGCCGGCTGGTGCTGGTG
GTCGACGACAGCGAATACGACCGGTTCTTCATCGCCTCGCTCTTCAAGGAGATGGGGATGGACGTGCTCTTGGCCGAGGA
CGGCGCGCAGGCCCTGGAAATCGCCGCAGCCGACCGGCCCGACCTGATCACTCTCGACCTGCTGATGCCCGGGATGGACG
GCGCGGCCGTGTTGGACAAGCTCAGGTCCAACCAGTCCACCGCGGCAATTCCTGTGGTGGTGATAACTTCCAAGGATCTG
AACTCGGCGGAGTTGGAGCGCCTCTCCTCCGGGGTGAGCGCCATCCTTTCCAAGGGGGGGCTCGAGCGCGAGGTGGTGCT
GGACGAATTGGTGCACAGCCTGGAGCGGATCGGCTGGCGCCTTCCCTGCGAGCAAAGCGCAAACGGGGCGAGGATCCTCA
TCGTCGAGGACAGCGAGGCGGCCACCATCCAGCTCCGCTTCGCGCTGGAAAGCGCCGGGTTCTGCGTCGACGCCGTCTCA
GGCGGCAGACATGCTCTTTCCTATCTGAAGACCCACGTGCCCGACGGTATCATCCTCGACCTGATGATGCCGGAGGTGGA
CGGCTTCGACGTGTTGAAAGCGGTGCGCGCCTCGCGGCTGACCGAACAGGTGCCGGTCATGGTGATGACGGCGAAGACCC
TTTCGCCGGGCGAGCACGACCGGTTGCGCCTGCTCGAGGTGAACCACCTGGTCCAAAAAGGGGACGTGGAGCAGCACGAA
CTGCTGCGGAGAGTCTACGAGATGCTCGGGGCGGTATGCCTGTTCAAGCCGGGCACCGCGTCGACGGCGACCGGCGCCGC
GCTTTTCCCCGGGGGCTGGCAGGGGGACGGGTCGGTGCTGGTGGTCGAGGACAACCCGGACAACCTGGTAACGCTTCGGG
CCGTTTTGGGGGAGGAGTACCGCCTGGTCGAGGCGACCGACGGCGAGTCCGGGCTTCTCCTGGCGCAGACAGGGTCCCCT
TCGCTGATCCTTTTGGACATGCATCTCCCCGGCATGGACGGACTCGCCGTACTAAGGCGCCTGAAGCAGGATAATGCCAC
GGCTCTCATCCCGGTGGTGGCCCTCACCGCGAGCGCCATGACGGGGGACCGGGAGATGCTGATGGAGGCGGGTTGCGTGG
CCTACGTCTCCAAGCCCTACCAGCCGGAAGAGTTGCAGGAACTGGTCACCAAATTCGTCGCAGCGGGGACTGCGCCAAAC
GGGAAGTAA

Upstream 100 bases:

>100_bases
CCATAAATCTAGCGATGCTGCGGGAGGTCATGGCTGACTCCGACAGGTACGCCCTGAGAGGGTTCGACTACCGCGGCAAT
ACCGAAACGGATGGAACAAG

Downstream 100 bases:

>100_bases
AACCGGCCCCCCTTTTAGCAGTCGAGGAAACCGTTAAATGAAAATTCTCGCCATAGACGACAACCACGACAATCTCCTCA
CGCTGAAGGCGCTGCTGAAG

Product: sensor histidine kinase response receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1362; Mature: 1362

Protein sequence:

>1362_residues
MKKLIKLPTLRARLAFWFTAICLVPLFLVTTIIYMQRVKLARSLMFDKLNAVTSLRQQQIGSILDNMIVDASTIASDHSV
LETAEQLLSGAGGGRVTSESLTLLRGYQSSNASVTDVSIVSHDGTVVLCTSDSRIGTRVARPEMVGNALQDLAPTFGDAY
LGSDGIPSIDVAVPIGAATKSRVGALLVARYNLHTLLYDITGNRTGMGDTGETVLVNREVMPLNELRAFSQGILKVPLKG
KPAQMAARGESGIAQTTDYRGVDVLSAFVHIPRTGWGLVCKQDSREILAPIRSLLFITYGLAALISVFACLLAFRLARSI
ADPLVNLAASAKELEDGDFDARAVPEGTDEQKTLARSFNSMARTLQTKMAAQQGMSRLSQNLVVAEGMDDFFSKLLPVFL
EITGARMAVAYVEERQTGEFAPMHAIGLDSSLLRRFQRRHLEGELGVILASGTVSCYTPQEGSPLRFATSFGEIVPAEIA
TVPISVDAEIRAFVSIASERPFPPKVHEILELVQMPLGAAFARILSGEDVRLLANELALKNEELTQQSEELVQQSTELAH
QSEELSRHNQVLDLQKQQLEEATRLKSEFLSNMSHELRTPLNSVLALSRVLAVQGGSRLTEDEKGYLSIIERNGKHLLSL
INDILDLAKIESGRQEVYLETVSLQKVTAEVVDGLSVLAREKGIAISLEAPEALPTAVIDVKRLRQMLQNLIGNAVKFTA
EGAVTVRLGAEGEEFLVEVEDTGIGIAPQYLETIFHEFRQADGSTSRSFEGTGLGLAIVKKTARLLGGDVSVRSELGKGS
VFTLRLPCDGTGSVQGPQASGNASFPAERAQAPMQGRSVLVVDDDPEAVSLIASHLSQAGFETLTALNGADALRLARAKK
PFAITLDIMMPDMDGWEVMRELKDQRETADIPVVIVSLSDDRATGIALGAVGVIAKPVSREQLIETFTKLAGAGCRLVLV
VDDSEYDRFFIASLFKEMGMDVLLAEDGAQALEIAAADRPDLITLDLLMPGMDGAAVLDKLRSNQSTAAIPVVVITSKDL
NSAELERLSSGVSAILSKGGLEREVVLDELVHSLERIGWRLPCEQSANGARILIVEDSEAATIQLRFALESAGFCVDAVS
GGRHALSYLKTHVPDGIILDLMMPEVDGFDVLKAVRASRLTEQVPVMVMTAKTLSPGEHDRLRLLEVNHLVQKGDVEQHE
LLRRVYEMLGAVCLFKPGTASTATGAALFPGGWQGDGSVLVVEDNPDNLVTLRAVLGEEYRLVEATDGESGLLLAQTGSP
SLILLDMHLPGMDGLAVLRRLKQDNATALIPVVALTASAMTGDREMLMEAGCVAYVSKPYQPEELQELVTKFVAAGTAPN
GK

Sequences:

>Translated_1362_residues
MKKLIKLPTLRARLAFWFTAICLVPLFLVTTIIYMQRVKLARSLMFDKLNAVTSLRQQQIGSILDNMIVDASTIASDHSV
LETAEQLLSGAGGGRVTSESLTLLRGYQSSNASVTDVSIVSHDGTVVLCTSDSRIGTRVARPEMVGNALQDLAPTFGDAY
LGSDGIPSIDVAVPIGAATKSRVGALLVARYNLHTLLYDITGNRTGMGDTGETVLVNREVMPLNELRAFSQGILKVPLKG
KPAQMAARGESGIAQTTDYRGVDVLSAFVHIPRTGWGLVCKQDSREILAPIRSLLFITYGLAALISVFACLLAFRLARSI
ADPLVNLAASAKELEDGDFDARAVPEGTDEQKTLARSFNSMARTLQTKMAAQQGMSRLSQNLVVAEGMDDFFSKLLPVFL
EITGARMAVAYVEERQTGEFAPMHAIGLDSSLLRRFQRRHLEGELGVILASGTVSCYTPQEGSPLRFATSFGEIVPAEIA
TVPISVDAEIRAFVSIASERPFPPKVHEILELVQMPLGAAFARILSGEDVRLLANELALKNEELTQQSEELVQQSTELAH
QSEELSRHNQVLDLQKQQLEEATRLKSEFLSNMSHELRTPLNSVLALSRVLAVQGGSRLTEDEKGYLSIIERNGKHLLSL
INDILDLAKIESGRQEVYLETVSLQKVTAEVVDGLSVLAREKGIAISLEAPEALPTAVIDVKRLRQMLQNLIGNAVKFTA
EGAVTVRLGAEGEEFLVEVEDTGIGIAPQYLETIFHEFRQADGSTSRSFEGTGLGLAIVKKTARLLGGDVSVRSELGKGS
VFTLRLPCDGTGSVQGPQASGNASFPAERAQAPMQGRSVLVVDDDPEAVSLIASHLSQAGFETLTALNGADALRLARAKK
PFAITLDIMMPDMDGWEVMRELKDQRETADIPVVIVSLSDDRATGIALGAVGVIAKPVSREQLIETFTKLAGAGCRLVLV
VDDSEYDRFFIASLFKEMGMDVLLAEDGAQALEIAAADRPDLITLDLLMPGMDGAAVLDKLRSNQSTAAIPVVVITSKDL
NSAELERLSSGVSAILSKGGLEREVVLDELVHSLERIGWRLPCEQSANGARILIVEDSEAATIQLRFALESAGFCVDAVS
GGRHALSYLKTHVPDGIILDLMMPEVDGFDVLKAVRASRLTEQVPVMVMTAKTLSPGEHDRLRLLEVNHLVQKGDVEQHE
LLRRVYEMLGAVCLFKPGTASTATGAALFPGGWQGDGSVLVVEDNPDNLVTLRAVLGEEYRLVEATDGESGLLLAQTGSP
SLILLDMHLPGMDGLAVLRRLKQDNATALIPVVALTASAMTGDREMLMEAGCVAYVSKPYQPEELQELVTKFVAAGTAPN
GK
>Mature_1362_residues
MKKLIKLPTLRARLAFWFTAICLVPLFLVTTIIYMQRVKLARSLMFDKLNAVTSLRQQQIGSILDNMIVDASTIASDHSV
LETAEQLLSGAGGGRVTSESLTLLRGYQSSNASVTDVSIVSHDGTVVLCTSDSRIGTRVARPEMVGNALQDLAPTFGDAY
LGSDGIPSIDVAVPIGAATKSRVGALLVARYNLHTLLYDITGNRTGMGDTGETVLVNREVMPLNELRAFSQGILKVPLKG
KPAQMAARGESGIAQTTDYRGVDVLSAFVHIPRTGWGLVCKQDSREILAPIRSLLFITYGLAALISVFACLLAFRLARSI
ADPLVNLAASAKELEDGDFDARAVPEGTDEQKTLARSFNSMARTLQTKMAAQQGMSRLSQNLVVAEGMDDFFSKLLPVFL
EITGARMAVAYVEERQTGEFAPMHAIGLDSSLLRRFQRRHLEGELGVILASGTVSCYTPQEGSPLRFATSFGEIVPAEIA
TVPISVDAEIRAFVSIASERPFPPKVHEILELVQMPLGAAFARILSGEDVRLLANELALKNEELTQQSEELVQQSTELAH
QSEELSRHNQVLDLQKQQLEEATRLKSEFLSNMSHELRTPLNSVLALSRVLAVQGGSRLTEDEKGYLSIIERNGKHLLSL
INDILDLAKIESGRQEVYLETVSLQKVTAEVVDGLSVLAREKGIAISLEAPEALPTAVIDVKRLRQMLQNLIGNAVKFTA
EGAVTVRLGAEGEEFLVEVEDTGIGIAPQYLETIFHEFRQADGSTSRSFEGTGLGLAIVKKTARLLGGDVSVRSELGKGS
VFTLRLPCDGTGSVQGPQASGNASFPAERAQAPMQGRSVLVVDDDPEAVSLIASHLSQAGFETLTALNGADALRLARAKK
PFAITLDIMMPDMDGWEVMRELKDQRETADIPVVIVSLSDDRATGIALGAVGVIAKPVSREQLIETFTKLAGAGCRLVLV
VDDSEYDRFFIASLFKEMGMDVLLAEDGAQALEIAAADRPDLITLDLLMPGMDGAAVLDKLRSNQSTAAIPVVVITSKDL
NSAELERLSSGVSAILSKGGLEREVVLDELVHSLERIGWRLPCEQSANGARILIVEDSEAATIQLRFALESAGFCVDAVS
GGRHALSYLKTHVPDGIILDLMMPEVDGFDVLKAVRASRLTEQVPVMVMTAKTLSPGEHDRLRLLEVNHLVQKGDVEQHE
LLRRVYEMLGAVCLFKPGTASTATGAALFPGGWQGDGSVLVVEDNPDNLVTLRAVLGEEYRLVEATDGESGLLLAQTGSP
SLILLDMHLPGMDGLAVLRRLKQDNATALIPVVALTASAMTGDREMLMEAGCVAYVSKPYQPEELQELVTKFVAAGTAPN
GK

Specific function: Forms part of a two-component regulatory system gacA/gacS(lemA). May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N- acyl-L-homoserine lactone (acyl-HSL). Required for pathogenicity on bean [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=560, Percent_Identity=29.6428571428571, Blast_Score=206, Evalue=8e-54,
Organism=Escherichia coli, GI48994928, Length=449, Percent_Identity=33.4075723830735, Blast_Score=197, Evalue=3e-51,
Organism=Escherichia coli, GI87081816, Length=392, Percent_Identity=33.9285714285714, Blast_Score=169, Evalue=1e-42,
Organism=Escherichia coli, GI145693157, Length=498, Percent_Identity=27.3092369477912, Blast_Score=167, Evalue=6e-42,
Organism=Escherichia coli, GI1788713, Length=390, Percent_Identity=30.2564102564103, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=29.2372881355932, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=31.1111111111111, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=32.6359832635983, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1786783, Length=233, Percent_Identity=27.4678111587983, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1790436, Length=249, Percent_Identity=29.3172690763052, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1790346, Length=202, Percent_Identity=28.7128712871287, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1788279, Length=223, Percent_Identity=31.390134529148, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=253, Percent_Identity=29.6442687747036, Blast_Score=84, Evalue=8e-17,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=30.0448430493274, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=25.4901960784314, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=201, Percent_Identity=28.8557213930348, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=27.5720164609054, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1786911, Length=127, Percent_Identity=37.7952755905512, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1786599, Length=108, Percent_Identity=38.8888888888889, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=353, Percent_Identity=27.1954674220963, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 146714; Mature: 146714

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50885 HAMP ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLIKLPTLRARLAFWFTAICLVPLFLVTTIIYMQRVKLARSLMFDKLNAVTSLRQQQI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSILDNMIVDASTIASDHSVLETAEQLLSGAGGGRVTSESLTLLRGYQSSNASVTDVSIV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCCCCCEEEEEEE
SHDGTVVLCTSDSRIGTRVARPEMVGNALQDLAPTFGDAYLGSDGIPSIDVAVPIGAATK
ECCCEEEEEECCCCCCCHHCCHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEEEECCCCCH
SRVGALLVARYNLHTLLYDITGNRTGMGDTGETVLVNREVMPLNELRAFSQGILKVPLKG
HHHCEEEEEEECEEEEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCEEECCCCC
KPAQMAARGESGIAQTTDYRGVDVLSAFVHIPRTGWGLVCKQDSREILAPIRSLLFITYG
CCHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
LAALISVFACLLAFRLARSIADPLVNLAASAKELEDGDFDARAVPEGTDEQKTLARSFNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
MARTLQTKMAAQQGMSRLSQNLVVAEGMDDFFSKLLPVFLEITGARMAVAYVEERQTGEF
HHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCC
APMHAIGLDSSLLRRFQRRHLEGELGVILASGTVSCYTPQEGSPLRFATSFGEIVPAEIA
CCCCEECCCHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCEEEEHHHCCCCCCHHE
TVPISVDAEIRAFVSIASERPFPPKVHEILELVQMPLGAAFARILSGEDVRLLANELALK
EEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHC
NEELTQQSEELVQQSTELAHQSEELSRHNQVLDLQKQQLEEATRLKSEFLSNMSHELRTP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
LNSVLALSRVLAVQGGSRLTEDEKGYLSIIERNGKHLLSLINDILDLAKIESGRQEVYLE
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEE
TVSLQKVTAEVVDGLSVLAREKGIAISLEAPEALPTAVIDVKRLRQMLQNLIGNAVKFTA
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEE
EGAVTVRLGAEGEEFLVEVEDTGIGIAPQYLETIFHEFRQADGSTSRSFEGTGLGLAIVK
CCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
KTARLLGGDVSVRSELGKGSVFTLRLPCDGTGSVQGPQASGNASFPAERAQAPMQGRSVL
HHHHHHCCCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEE
VVDDDPEAVSLIASHLSQAGFETLTALNGADALRLARAKKPFAITLDIMMPDMDGWEVMR
EECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEEEECCCCHHHHHH
ELKDQRETADIPVVIVSLSDDRATGIALGAVGVIAKPVSREQLIETFTKLAGAGCRLVLV
HHHHHHCCCCCCEEEEEECCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEE
VDDSEYDRFFIASLFKEMGMDVLLAEDGAQALEIAAADRPDLITLDLLMPGMDGAAVLDK
EECCCCCHHHHHHHHHHCCCEEEEECCCCHHEEEEECCCCCEEEEEEECCCCCHHHHHHH
LRSNQSTAAIPVVVITSKDLNSAELERLSSGVSAILSKGGLEREVVLDELVHSLERIGWR
HHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
LPCEQSANGARILIVEDSEAATIQLRFALESAGFCVDAVSGGRHALSYLKTHVPDGIILD
CCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCCEEEECCCCHHHHHHHHHHCCCCEEEE
LMMPEVDGFDVLKAVRASRLTEQVPVMVMTAKTLSPGEHDRLRLLEVNHLVQKGDVEQHE
EECCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEHHHHHHHCCCCHHHH
LLRRVYEMLGAVCLFKPGTASTATGAALFPGGWQGDGSVLVVEDNPDNLVTLRAVLGEEY
HHHHHHHHHCHHEEECCCCCCCCCCCEECCCCCCCCCCEEEEECCCCCEEEEHHHHCCCE
RLVEATDGESGLLLAQTGSPSLILLDMHLPGMDGLAVLRRLKQDNATALIPVVALTASAM
EEEEECCCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHC
TGDREMLMEAGCVAYVSKPYQPEELQELVTKFVAAGTAPNGK
CCCHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKKLIKLPTLRARLAFWFTAICLVPLFLVTTIIYMQRVKLARSLMFDKLNAVTSLRQQQI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSILDNMIVDASTIASDHSVLETAEQLLSGAGGGRVTSESLTLLRGYQSSNASVTDVSIV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCCCCCEEEEEEE
SHDGTVVLCTSDSRIGTRVARPEMVGNALQDLAPTFGDAYLGSDGIPSIDVAVPIGAATK
ECCCEEEEEECCCCCCCHHCCHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEEEECCCCCH
SRVGALLVARYNLHTLLYDITGNRTGMGDTGETVLVNREVMPLNELRAFSQGILKVPLKG
HHHCEEEEEEECEEEEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCEEECCCCC
KPAQMAARGESGIAQTTDYRGVDVLSAFVHIPRTGWGLVCKQDSREILAPIRSLLFITYG
CCHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
LAALISVFACLLAFRLARSIADPLVNLAASAKELEDGDFDARAVPEGTDEQKTLARSFNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
MARTLQTKMAAQQGMSRLSQNLVVAEGMDDFFSKLLPVFLEITGARMAVAYVEERQTGEF
HHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCC
APMHAIGLDSSLLRRFQRRHLEGELGVILASGTVSCYTPQEGSPLRFATSFGEIVPAEIA
CCCCEECCCHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCEEEEHHHCCCCCCHHE
TVPISVDAEIRAFVSIASERPFPPKVHEILELVQMPLGAAFARILSGEDVRLLANELALK
EEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHC
NEELTQQSEELVQQSTELAHQSEELSRHNQVLDLQKQQLEEATRLKSEFLSNMSHELRTP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
LNSVLALSRVLAVQGGSRLTEDEKGYLSIIERNGKHLLSLINDILDLAKIESGRQEVYLE
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEE
TVSLQKVTAEVVDGLSVLAREKGIAISLEAPEALPTAVIDVKRLRQMLQNLIGNAVKFTA
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEE
EGAVTVRLGAEGEEFLVEVEDTGIGIAPQYLETIFHEFRQADGSTSRSFEGTGLGLAIVK
CCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
KTARLLGGDVSVRSELGKGSVFTLRLPCDGTGSVQGPQASGNASFPAERAQAPMQGRSVL
HHHHHHCCCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEE
VVDDDPEAVSLIASHLSQAGFETLTALNGADALRLARAKKPFAITLDIMMPDMDGWEVMR
EECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEEEECCCCHHHHHH
ELKDQRETADIPVVIVSLSDDRATGIALGAVGVIAKPVSREQLIETFTKLAGAGCRLVLV
HHHHHHCCCCCCEEEEEECCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEE
VDDSEYDRFFIASLFKEMGMDVLLAEDGAQALEIAAADRPDLITLDLLMPGMDGAAVLDK
EECCCCCHHHHHHHHHHCCCEEEEECCCCHHEEEEECCCCCEEEEEEECCCCCHHHHHHH
LRSNQSTAAIPVVVITSKDLNSAELERLSSGVSAILSKGGLEREVVLDELVHSLERIGWR
HHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
LPCEQSANGARILIVEDSEAATIQLRFALESAGFCVDAVSGGRHALSYLKTHVPDGIILD
CCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCCEEEECCCCHHHHHHHHHHCCCCEEEE
LMMPEVDGFDVLKAVRASRLTEQVPVMVMTAKTLSPGEHDRLRLLEVNHLVQKGDVEQHE
EECCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEHHHHHHHCCCCHHHH
LLRRVYEMLGAVCLFKPGTASTATGAALFPGGWQGDGSVLVVEDNPDNLVTLRAVLGEEY
HHHHHHHHHCHHEEECCCCCCCCCCCEECCCCCCCCCCEEEEECCCCCEEEEHHHHCCCE
RLVEATDGESGLLLAQTGSPSLILLDMHLPGMDGLAVLRRLKQDNATALIPVVALTASAM
EEEEECCCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHC
TGDREMLMEAGCVAYVSKPYQPEELQELVTKFVAAGTAPNGK
CCCHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1314807 [H]