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The map label for this gene is cph1 [H]

Identifier: 197118832

GI number: 197118832

Start: 2843807

End: 2845195

Strand: Reverse

Name: cph1 [H]

Synonym: Gbem_2455

Alternate gene names: 197118832

Gene position: 2845195-2843807 (Counterclockwise)

Preceding gene: 197118833

Following gene: 197118831

Centisome position: 61.65

GC content: 63.07

Gene sequence:

>1389_bases
TTGGAGCTGAAGTCGCGCGTTTTTAGCTGGGCCAGGCTCTCCGAGCCCGGAGCCAAATCCTTCCTGCTCCAGGCGCTGCT
GGGGGGTGGGCTTACCTTCCTCTTCTGGCTGCTCCAGGCGGCCATCGACTATTTCCTTTTCGGCGGCAACTCCTTTTACA
AATACCTATTGCATCCGGACCGGCACCAGGCGGCGGAGTTTTCCCTGGTGGTCTTTCTGGTCTGCTGCCTGCTCCTTTAC
AGCAGGCACTCCCACCAGTTGCAGGCTCAACTGCAAGCGGCGCTTAAGACAGCGCTCGACAAGTCCGAGGACGACAAGGT
AAAACTGCGCGGCATCGTCGAGGCGATGGGAGACGCCATCTCCATCCAGGCGCCGGATATGACCATCGTCTACCAAAACC
GCGCCCACGTCGAGATGATGGGGCAGCATGTCGGAGAGCCTTGCTACCAGGCGTACCGCCAGGAAAAGGAAATCTGCCCC
GGCTGCCACCTGGCGGCGGCCTTCGCGGACGGCAAGGTGCACCGCGCCAAGGTGAGTCCGGAGCCTGGCAACGGCAACCG
CTACGTAGAGATAACGGGCTCGGTGCTGAACGGGGCCGACGGCAGGCCCGCCCTCGGCATAGAGGTGGTGCGGGACGTCA
CGGCGCAGCGGCTGGTAGAGCGCGAGGCGGCCCAGTTGAACCTGGCCCTCACCCGGCAGGCCACCGAACTGAAGCAGGTG
AACCGTGAGTTGGAGGCCTTCTGCCTGGCGGTTGCCCACGATCTGCGCGCGCCGCTTACCCGGATCTACAGTTCCGCCCA
GGAACTGCAGGGGTATTGCGATTTGCTGGACGAAAACGGCCGTTTCTTTGTGTCGCTCGTGAATGACGGCTGCGTCCATA
TGGAGTCGATGATCGAGGCGCTGATGATCCTTTGCCATGTGACGGAGATGGAGATGGCGCCCGCTCCGGTGGACCTGGCC
GAACTGGTGCAGGAACTGGCGGCGCAACTGCAGCTGGACCATCCCGGGCGCAAGGTGACCCTGCGCCTGCCCGAGCGGCT
CGTGGTCCAGGGGGACCGGGAGCTCTTGCGCATCGCCATGGAGAACCTCTTGTCCAACGCCTGGAAGTACACCTCCCACG
TGGCTATGCCCCTGATAGAACTCGGTTCTTTCGGTAGCGAGCAAGGGGAGCTCGTGATATTTCTGAGAGACAACGGCGCA
GGGTTCGACAACGCCCGTGCCGAGGAGCTCTTCAAACCGTTCAGGCGCCTACACTCCGCCCTGGAGTTTCCCGGTACCGG
CCTTGGGCTCGCCACGGTACGCCGCATCATTCGCCGGCACAACGGCCAGATCTGGGGAGACGGCACACCCGGGGCCGGCG
CGACTTTCTACTTTACCGTCAACGGGTGA

Upstream 100 bases:

>100_bases
GCTGCGGCGCGCTCGTCATCGCCAGGTACGGGTATGTGGTGGAGAAAAACCTCCTGGCGCAGGGGCGCTGTCCCGCCTGC
GGCGCCGGGGTGGAGGGAGT

Downstream 100 bases:

>100_bases
CTCACGGCTGGAAACGGTTGCCCCCGGTCGGCCATTCATGCTATAAATCATCGTTCCGCAATAAAATCCACTGCATGAAG
GGGTTTCTTCCTTGAAGGTT

Product: sensor histidine kinase heme-binding site

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MELKSRVFSWARLSEPGAKSFLLQALLGGGLTFLFWLLQAAIDYFLFGGNSFYKYLLHPDRHQAAEFSLVVFLVCCLLLY
SRHSHQLQAQLQAALKTALDKSEDDKVKLRGIVEAMGDAISIQAPDMTIVYQNRAHVEMMGQHVGEPCYQAYRQEKEICP
GCHLAAAFADGKVHRAKVSPEPGNGNRYVEITGSVLNGADGRPALGIEVVRDVTAQRLVEREAAQLNLALTRQATELKQV
NRELEAFCLAVAHDLRAPLTRIYSSAQELQGYCDLLDENGRFFVSLVNDGCVHMESMIEALMILCHVTEMEMAPAPVDLA
ELVQELAAQLQLDHPGRKVTLRLPERLVVQGDRELLRIAMENLLSNAWKYTSHVAMPLIELGSFGSEQGELVIFLRDNGA
GFDNARAEELFKPFRRLHSALEFPGTGLGLATVRRIIRRHNGQIWGDGTPGAGATFYFTVNG

Sequences:

>Translated_462_residues
MELKSRVFSWARLSEPGAKSFLLQALLGGGLTFLFWLLQAAIDYFLFGGNSFYKYLLHPDRHQAAEFSLVVFLVCCLLLY
SRHSHQLQAQLQAALKTALDKSEDDKVKLRGIVEAMGDAISIQAPDMTIVYQNRAHVEMMGQHVGEPCYQAYRQEKEICP
GCHLAAAFADGKVHRAKVSPEPGNGNRYVEITGSVLNGADGRPALGIEVVRDVTAQRLVEREAAQLNLALTRQATELKQV
NRELEAFCLAVAHDLRAPLTRIYSSAQELQGYCDLLDENGRFFVSLVNDGCVHMESMIEALMILCHVTEMEMAPAPVDLA
ELVQELAAQLQLDHPGRKVTLRLPERLVVQGDRELLRIAMENLLSNAWKYTSHVAMPLIELGSFGSEQGELVIFLRDNGA
GFDNARAEELFKPFRRLHSALEFPGTGLGLATVRRIIRRHNGQIWGDGTPGAGATFYFTVNG
>Mature_462_residues
MELKSRVFSWARLSEPGAKSFLLQALLGGGLTFLFWLLQAAIDYFLFGGNSFYKYLLHPDRHQAAEFSLVVFLVCCLLLY
SRHSHQLQAQLQAALKTALDKSEDDKVKLRGIVEAMGDAISIQAPDMTIVYQNRAHVEMMGQHVGEPCYQAYRQEKEICP
GCHLAAAFADGKVHRAKVSPEPGNGNRYVEITGSVLNGADGRPALGIEVVRDVTAQRLVEREAAQLNLALTRQATELKQV
NRELEAFCLAVAHDLRAPLTRIYSSAQELQGYCDLLDENGRFFVSLVNDGCVHMESMIEALMILCHVTEMEMAPAPVDLA
ELVQELAAQLQLDHPGRKVTLRLPERLVVQGDRELLRIAMENLLSNAWKYTSHVAMPLIELGSFGSEQGELVIFLRDNGA
GFDNARAEELFKPFRRLHSALEFPGTGLGLATVRRIIRRHNGQIWGDGTPGAGATFYFTVNG

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=30.379746835443, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=23.7885462555066, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788549, Length=318, Percent_Identity=27.6729559748428, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1789808, Length=227, Percent_Identity=27.7533039647577, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI48994928, Length=360, Percent_Identity=23.0555555555556, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=25.974025974026, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=112, Percent_Identity=38.3928571428571, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786600, Length=252, Percent_Identity=26.1904761904762, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87081816, Length=241, Percent_Identity=26.9709543568465, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=261, Percent_Identity=25.2873563218391, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=25, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788393, Length=244, Percent_Identity=25.4098360655738, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51290; Mature: 51290

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKSRVFSWARLSEPGAKSFLLQALLGGGLTFLFWLLQAAIDYFLFGGNSFYKYLLHPD
CCHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCHHHHEEECCC
RHQAAEFSLVVFLVCCLLLYSRHSHQLQAQLQAALKTALDKSEDDKVKLRGIVEAMGDAI
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEE
SIQAPDMTIVYQNRAHVEMMGQHVGEPCYQAYRQEKEICPGCHLAAAFADGKVHRAKVSP
EEECCCEEEEECCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCC
EPGNGNRYVEITGSVLNGADGRPALGIEVVRDVTAQRLVEREAAQLNLALTRQATELKQV
CCCCCCEEEEEECHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRELEAFCLAVAHDLRAPLTRIYSSAQELQGYCDLLDENGRFFVSLVNDGCVHMESMIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHH
LMILCHVTEMEMAPAPVDLAELVQELAAQLQLDHPGRKVTLRLPERLVVQGDRELLRIAM
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHCCCHHHHHHHH
ENLLSNAWKYTSHVAMPLIELGSFGSEQGELVIFLRDNGAGFDNARAEELFKPFRRLHSA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
LEFPGTGLGLATVRRIIRRHNGQIWGDGTPGAGATFYFTVNG
HCCCCCCCCHHHHHHHHHHHCCEEECCCCCCCCEEEEEEECC
>Mature Secondary Structure
MELKSRVFSWARLSEPGAKSFLLQALLGGGLTFLFWLLQAAIDYFLFGGNSFYKYLLHPD
CCHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCHHHHEEECCC
RHQAAEFSLVVFLVCCLLLYSRHSHQLQAQLQAALKTALDKSEDDKVKLRGIVEAMGDAI
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEE
SIQAPDMTIVYQNRAHVEMMGQHVGEPCYQAYRQEKEICPGCHLAAAFADGKVHRAKVSP
EEECCCEEEEECCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCC
EPGNGNRYVEITGSVLNGADGRPALGIEVVRDVTAQRLVEREAAQLNLALTRQATELKQV
CCCCCCEEEEEECHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRELEAFCLAVAHDLRAPLTRIYSSAQELQGYCDLLDENGRFFVSLVNDGCVHMESMIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHH
LMILCHVTEMEMAPAPVDLAELVQELAAQLQLDHPGRKVTLRLPERLVVQGDRELLRIAM
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHCCCHHHHHHHH
ENLLSNAWKYTSHVAMPLIELGSFGSEQGELVIFLRDNGAGFDNARAEELFKPFRRLHSA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
LEFPGTGLGLATVRRIIRRHNGQIWGDGTPGAGATFYFTVNG
HCCCCCCCCHHHHHHHHHHHCCEEECCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]