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The map label for this gene is pagR [H]

Identifier: 197118818

GI number: 197118818

Start: 2830854

End: 2831138

Strand: Direct

Name: pagR [H]

Synonym: Gbem_2441

Alternate gene names: 197118818

Gene position: 2830854-2831138 (Clockwise)

Preceding gene: 197118817

Following gene: 197118823

Centisome position: 61.34

GC content: 58.95

Gene sequence:

>285_bases
GTGGCATTCGACAAGACGAAGGATTATGGCAAGGAAGCGGAAATGCTGAAGGTGCTCGGGCACCCGATCCGCCTCAAAAT
AGTGGCTGGACTCTGCACGCAGGAGTGCAACGTCAAACACATCTGGGAGTGCCTGGGGCTGCCGCAGGCGACGGTCTCCC
AACACCTGGCGCTTTTGAAGAACAAGGGGATCATAGAGGGTACCCGCGACGGCGTCGAGGTCCGTTACGCCGTGGTGAGC
CCGTTCGTGCGCAGGTTGATCGAGATACTGCACCAAGAGCCCTAA

Upstream 100 bases:

>100_bases
GCCACTTCAGCAAAAGGATCTACCGCTCCTAGAAGCTTTCCTTGACAAGCCCCATCAGTATATATAGATTAGCCCAAGAA
GAATCTACCGGAGGATACAC

Downstream 100 bases:

>100_bases
GCTTCCCGGCGGTTGAAGAAATGAAAAAAGGCCGCACCCTTTACAGGTGCGGCCTTTTCATGCGTCTTAGCTGCCGCTGA
TCTCCAGCTCCGCGATCCTA

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: Protective antigen repressor [H]

Number of amino acids: Translated: 94; Mature: 93

Protein sequence:

>94_residues
MAFDKTKDYGKEAEMLKVLGHPIRLKIVAGLCTQECNVKHIWECLGLPQATVSQHLALLKNKGIIEGTRDGVEVRYAVVS
PFVRRLIEILHQEP

Sequences:

>Translated_94_residues
MAFDKTKDYGKEAEMLKVLGHPIRLKIVAGLCTQECNVKHIWECLGLPQATVSQHLALLKNKGIIEGTRDGVEVRYAVVS
PFVRRLIEILHQEP
>Mature_93_residues
AFDKTKDYGKEAEMLKVLGHPIRLKIVAGLCTQECNVKHIWECLGLPQATVSQHLALLKNKGIIEGTRDGVEVRYAVVSP
FVRRLIEILHQEP

Specific function: Represses the expression of the pagA and atxA genes [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 10593; Mature: 10461

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDKTKDYGKEAEMLKVLGHPIRLKIVAGLCTQECNVKHIWECLGLPQATVSQHLALLK
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHH
NKGIIEGTRDGVEVRYAVVSPFVRRLIEILHQEP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AFDKTKDYGKEAEMLKVLGHPIRLKIVAGLCTQECNVKHIWECLGLPQATVSQHLALLK
CCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHH
NKGIIEGTRDGVEVRYAVVSPFVRRLIEILHQEP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10419943; 10515943; 12004073; 12067380; 10475965 [H]