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The map label for this gene is fbp

Identifier: 197118789

GI number: 197118789

Start: 2789956

End: 2790936

Strand: Reverse

Name: fbp

Synonym: Gbem_2410

Alternate gene names: 197118789

Gene position: 2790936-2789956 (Counterclockwise)

Preceding gene: 197118790

Following gene: 197118788

Centisome position: 60.47

GC content: 60.24

Gene sequence:

>981_bases
ATGTCTAATGCACCGGGTACGTCCAAATTCCAAATAGATCTGCGCCGCCATCTGCGTGCCCAGAACATTTGCGATAACCT
CGTTCACCTCATGTGCGAAATTGCCGAGGCCAGCAAGTACGTCATCAACGCCGTACGCACCGGTGACCTCGGCGTCGCCG
GTACCTCCAACTTGTACGGCGAGGAGCAACTCGCGCTCGACGTACTCTCCGACCGCATCATGCGCAAGCGCCTGATCCAC
TCCGGCGTGGTCTGCAACATCGCCTCGGAGGAGATGGACGAGATCTACCAGTGTCAGGCCAGCGCCGACGGCCTCTATTC
CGTCGCCTACGATCCGCTTGACGGCTCGTCGCTCGTGGACGTGAACCTTGCGGTAGGTACCATCGTCTCCATCTACGCCG
GCTGCGATCTGCTCCAGCCCGGCCGCAATCAGGTCGCCGCCATGTACATCCTCTACGGACCGAGGGTTTCCCTGGTCTAC
ACCGTGGGCGACGGGGTGCACGAGTTCACCATGAACAACCTGATGGAGTTCACCCTGACCCGCGAGAACGTCAAGATGGC
TCCGGAAGGGAACATCTACGCCCCCGGCGGCCTGCGGAACAAGTACAACGCCGGCGACGAGAAGTTCATCCGCCATCTGG
AGGAGAAAGGGTGCAAGCTTCGCTACTCCGGCGGCTTCGTTCCCGATATCAACCAGGTCCTGATGAAGGGGAAAGGGCTC
TTCATGTACCCGGCGCTGAACGGTTCCCCCAACGGAAAGCTGCGCGTCCTTTTCGAACTGAACCCCATGGCTTTCATCAT
CGAGCATGCCGGCGGCGCCGCCAGCAACGGCAGCATCCCGATCCTCGACATCGTTCCCGAATCGCTCGACCAGAGGGCGC
CGATCTACATCGGCTGCAGGGAAGACGTAAAGACCGCGACCTCGTTCGTCAACGGCGGCAAGCAAGAGGTCAAGATGGCA
GGCTCATTTGTAAACGGGTAG

Upstream 100 bases:

>100_bases
GCTCTGCCTCGCGGTCCGGCCATTTTTTCCTTGATTTATACAGGCATTTGACATACTCTACGTGGCCGTAAAATAATTTT
AATTTAATCTGGAGGGAGCC

Downstream 100 bases:

>100_bases
AGCTTTGTTGTAAGATGGACCGTCCCGAGGCAACTTTTCCCTAAAGTTGTCTCGGGAAAGGTCGATAGTAATTAATTAGT
AATTCTCAGAGGTAACATGA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSNAPGTSKFQIDLRRHLRAQNICDNLVHLMCEIAEASKYVINAVRTGDLGVAGTSNLYGEEQLALDVLSDRIMRKRLIH
SGVVCNIASEEMDEIYQCQASADGLYSVAYDPLDGSSLVDVNLAVGTIVSIYAGCDLLQPGRNQVAAMYILYGPRVSLVY
TVGDGVHEFTMNNLMEFTLTRENVKMAPEGNIYAPGGLRNKYNAGDEKFIRHLEEKGCKLRYSGGFVPDINQVLMKGKGL
FMYPALNGSPNGKLRVLFELNPMAFIIEHAGGAASNGSIPILDIVPESLDQRAPIYIGCREDVKTATSFVNGGKQEVKMA
GSFVNG

Sequences:

>Translated_326_residues
MSNAPGTSKFQIDLRRHLRAQNICDNLVHLMCEIAEASKYVINAVRTGDLGVAGTSNLYGEEQLALDVLSDRIMRKRLIH
SGVVCNIASEEMDEIYQCQASADGLYSVAYDPLDGSSLVDVNLAVGTIVSIYAGCDLLQPGRNQVAAMYILYGPRVSLVY
TVGDGVHEFTMNNLMEFTLTRENVKMAPEGNIYAPGGLRNKYNAGDEKFIRHLEEKGCKLRYSGGFVPDINQVLMKGKGL
FMYPALNGSPNGKLRVLFELNPMAFIIEHAGGAASNGSIPILDIVPESLDQRAPIYIGCREDVKTATSFVNGGKQEVKMA
GSFVNG
>Mature_325_residues
SNAPGTSKFQIDLRRHLRAQNICDNLVHLMCEIAEASKYVINAVRTGDLGVAGTSNLYGEEQLALDVLSDRIMRKRLIHS
GVVCNIASEEMDEIYQCQASADGLYSVAYDPLDGSSLVDVNLAVGTIVSIYAGCDLLQPGRNQVAAMYILYGPRVSLVYT
VGDGVHEFTMNNLMEFTLTRENVKMAPEGNIYAPGGLRNKYNAGDEKFIRHLEEKGCKLRYSGGFVPDINQVLMKGKGLF
MYPALNGSPNGKLRVLFELNPMAFIIEHAGGAASNGSIPILDIVPESLDQRAPIYIGCREDVKTATSFVNGGKQEVKMAG
SFVNG

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=297, Percent_Identity=38.047138047138, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI189083692, Length=315, Percent_Identity=35.8730158730159, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI16579888, Length=315, Percent_Identity=35.8730158730159, Blast_Score=165, Evalue=5e-41,
Organism=Escherichia coli, GI1790679, Length=279, Percent_Identity=40.8602150537634, Blast_Score=192, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17508131, Length=336, Percent_Identity=37.202380952381, Blast_Score=202, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6323409, Length=317, Percent_Identity=35.6466876971609, Blast_Score=171, Evalue=1e-43,
Organism=Drosophila melanogaster, GI45550998, Length=328, Percent_Identity=35.9756097560976, Blast_Score=177, Evalue=6e-45,
Organism=Drosophila melanogaster, GI19921562, Length=328, Percent_Identity=35.9756097560976, Blast_Score=177, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_GEOBB (B5EFV5)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002139216.1
- ProteinModelPortal:   B5EFV5
- SMR:   B5EFV5
- GeneID:   6782408
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_2410
- HOGENOM:   HBG731261
- OMA:   AMSISPE
- ProtClustDB:   PRK09293
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR020548
- InterPro:   IPR023079
- PANTHER:   PTHR11556
- PRINTS:   PR01958

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 35482; Mature: 35351

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00124 FBPASE

Important sites: BINDING 222-222 BINDING 253-253

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAPGTSKFQIDLRRHLRAQNICDNLVHLMCEIAEASKYVINAVRTGDLGVAGTSNLYG
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC
EEQLALDVLSDRIMRKRLIHSGVVCNIASEEMDEIYQCQASADGLYSVAYDPLDGSSLVD
CHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEE
VNLAVGTIVSIYAGCDLLQPGRNQVAAMYILYGPRVSLVYTVGDGVHEFTMNNLMEFTLT
EEHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEEEEECCCHHHHHHHHHHEEEEE
RENVKMAPEGNIYAPGGLRNKYNAGDEKFIRHLEEKGCKLRYSGGFVPDINQVLMKGKGL
CCCEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHCCCCE
FMYPALNGSPNGKLRVLFELNPMAFIIEHAGGAASNGSIPILDIVPESLDQRAPIYIGCR
EEEECCCCCCCCCEEEEEEECCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCEEEECH
EDVKTATSFVNGGKQEVKMAGSFVNG
HHHHHHHHHHCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
SNAPGTSKFQIDLRRHLRAQNICDNLVHLMCEIAEASKYVINAVRTGDLGVAGTSNLYG
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC
EEQLALDVLSDRIMRKRLIHSGVVCNIASEEMDEIYQCQASADGLYSVAYDPLDGSSLVD
CHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEE
VNLAVGTIVSIYAGCDLLQPGRNQVAAMYILYGPRVSLVYTVGDGVHEFTMNNLMEFTLT
EEHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEEEEECCCHHHHHHHHHHEEEEE
RENVKMAPEGNIYAPGGLRNKYNAGDEKFIRHLEEKGCKLRYSGGFVPDINQVLMKGKGL
CCCEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHCCCCE
FMYPALNGSPNGKLRVLFELNPMAFIIEHAGGAASNGSIPILDIVPESLDQRAPIYIGCR
EEEECCCCCCCCCEEEEEEECCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCEEEECH
EDVKTATSFVNGGKQEVKMAGSFVNG
HHHHHHHHHHCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA