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The map label for this gene is trpS [H]

Identifier: 197118679

GI number: 197118679

Start: 2669573

End: 2670556

Strand: Reverse

Name: trpS [H]

Synonym: Gbem_2298

Alternate gene names: 197118679

Gene position: 2670556-2669573 (Counterclockwise)

Preceding gene: 197118680

Following gene: 197118678

Centisome position: 57.86

GC content: 61.28

Gene sequence:

>984_bases
ATGAGCAATAACCGTATCGTTAGCGGCATGAGACCGACTGGTAAACTGCATCTGGGCCATTACCACGGGGTGCTCTCCAA
CTGGCTTGAGTTGCAGCGTAACTTCGAGTGCTTCTTCTTCGCTGCCGACTGGCATTCGCTGACCACGGAATACGCCACTA
CGGACGGTATCAAGGACAACATCAAAGAGATGGTGCTGGATTGGCTCGCTTTCGGGATCGATCCCGAGCAGAGCGTCATC
TTCGAGCAGAGCAGGGTTCCGCAGCATGCCGAATTGAACCTGATCCTCGGCATGATCACTCCGGTCTCCTGGCTGGAGCG
CAACCCCACCTACAAGGAGATGCAGGAGAACCTCACCACCAAGGACCTCTCCACCTTCGGCTTCCTGGGGTACCCGGTGC
TGATGGCCTCCGACATCATCGTCTACAAGGCCTCGCGCGTCCCGGTAGGCCAGGACCAGATCCCGCACCTGGAGATCACC
AGGGAGATCGCCCGCCGCTTCAACTACCTCTACGGCGAGGTCTTCCCCGAACCGGCCGCGCTCCTCACCGAGACCCCGAA
GGTGCTCGGCACCGACGGCAGGAAGATGAGCAAGTCCTACGGCAACGCCATCTTCCTCTCCGACGACGCCGAGGAGACCA
GGAAGAAGGTGATGTCTTACGTGACCGACACACAGCGTCCCTTCAAGAAGGACCCGGGCGAGCCGGACCGCTGCGTCGCT
TTCACGCTGCACTCGCTTTACGTGGATCAGGCCAAACGCGAAGAGATCGTCGTCGGCTGCCGCGGCGCCCAGCTTGGCTG
CGTGGATTGCAAGAAGATCCTGGCCCAGGCTATGGTCGATACCCTGGCGCCGCTCAGGGCCAAGCGCGCTGAGCTGGCCG
AGAAGCCGGGGCTGGTGAGCGAGGTGTTGGCAGAGGGAAGCCGTAAGGCCGAGGTAGTCGCCCGCCAGACCATGGAAGAA
GCACGCGCGGCGCTCAAGGTTTAA

Upstream 100 bases:

>100_bases
TTGGCGGGGCCACACAGCAACCTCGTTTTCGGAGTAACCAGGCTCATGCTGAAATAGCAGGGCCAAGTAGATAGAGAAAT
CCAAAAGGAGTCCGCATTCT

Downstream 100 bases:

>100_bases
ACCGCCAAACGGCCGTTCAACGTTCCAGGTTCAAGGTTCAACTTTCTGCTCACTTCAAGGGGGCGGCATCTTGACGGCAC
CGGTCGAACTGCCGTTCAAG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSNNRIVSGMRPTGKLHLGHYHGVLSNWLELQRNFECFFFAADWHSLTTEYATTDGIKDNIKEMVLDWLAFGIDPEQSVI
FEQSRVPQHAELNLILGMITPVSWLERNPTYKEMQENLTTKDLSTFGFLGYPVLMASDIIVYKASRVPVGQDQIPHLEIT
REIARRFNYLYGEVFPEPAALLTETPKVLGTDGRKMSKSYGNAIFLSDDAEETRKKVMSYVTDTQRPFKKDPGEPDRCVA
FTLHSLYVDQAKREEIVVGCRGAQLGCVDCKKILAQAMVDTLAPLRAKRAELAEKPGLVSEVLAEGSRKAEVVARQTMEE
ARAALKV

Sequences:

>Translated_327_residues
MSNNRIVSGMRPTGKLHLGHYHGVLSNWLELQRNFECFFFAADWHSLTTEYATTDGIKDNIKEMVLDWLAFGIDPEQSVI
FEQSRVPQHAELNLILGMITPVSWLERNPTYKEMQENLTTKDLSTFGFLGYPVLMASDIIVYKASRVPVGQDQIPHLEIT
REIARRFNYLYGEVFPEPAALLTETPKVLGTDGRKMSKSYGNAIFLSDDAEETRKKVMSYVTDTQRPFKKDPGEPDRCVA
FTLHSLYVDQAKREEIVVGCRGAQLGCVDCKKILAQAMVDTLAPLRAKRAELAEKPGLVSEVLAEGSRKAEVVARQTMEE
ARAALKV
>Mature_326_residues
SNNRIVSGMRPTGKLHLGHYHGVLSNWLELQRNFECFFFAADWHSLTTEYATTDGIKDNIKEMVLDWLAFGIDPEQSVIF
EQSRVPQHAELNLILGMITPVSWLERNPTYKEMQENLTTKDLSTFGFLGYPVLMASDIIVYKASRVPVGQDQIPHLEITR
EIARRFNYLYGEVFPEPAALLTETPKVLGTDGRKMSKSYGNAIFLSDDAEETRKKVMSYVTDTQRPFKKDPGEPDRCVAF
TLHSLYVDQAKREEIVVGCRGAQLGCVDCKKILAQAMVDTLAPLRAKRAELAEKPGLVSEVLAEGSRKAEVVARQTMEEA
RAALKV

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=328, Percent_Identity=33.5365853658537, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI41352700, Length=183, Percent_Identity=38.2513661202186, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1789786, Length=237, Percent_Identity=37.5527426160338, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71982800, Length=331, Percent_Identity=32.9305135951662, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71982793, Length=331, Percent_Identity=32.9305135951662, Blast_Score=153, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320474, Length=341, Percent_Identity=31.6715542521994, Blast_Score=151, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24666151, Length=329, Percent_Identity=33.7386018237082, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36818; Mature: 36686

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNRIVSGMRPTGKLHLGHYHGVLSNWLELQRNFECFFFAADWHSLTTEYATTDGIKDN
CCCCCEEECCCCCCEEECHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHCCCHHHH
IKEMVLDWLAFGIDPEQSVIFEQSRVPQHAELNLILGMITPVSWLERNPTYKEMQENLTT
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCH
KDLSTFGFLGYPVLMASDIIVYKASRVPVGQDQIPHLEITREIARRFNYLYGEVFPEPAA
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
LLTETPKVLGTDGRKMSKSYGNAIFLSDDAEETRKKVMSYVTDTQRPFKKDPGEPDRCVA
HHHCCCHHHCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
FTLHSLYVDQAKREEIVVGCRGAQLGCVDCKKILAQAMVDTLAPLRAKRAELAEKPGLVS
HHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EVLAEGSRKAEVVARQTMEEARAALKV
HHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNNRIVSGMRPTGKLHLGHYHGVLSNWLELQRNFECFFFAADWHSLTTEYATTDGIKDN
CCCCEEECCCCCCEEECHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHCCCHHHH
IKEMVLDWLAFGIDPEQSVIFEQSRVPQHAELNLILGMITPVSWLERNPTYKEMQENLTT
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCH
KDLSTFGFLGYPVLMASDIIVYKASRVPVGQDQIPHLEITREIARRFNYLYGEVFPEPAA
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
LLTETPKVLGTDGRKMSKSYGNAIFLSDDAEETRKKVMSYVTDTQRPFKKDPGEPDRCVA
HHHCCCHHHCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
FTLHSLYVDQAKREEIVVGCRGAQLGCVDCKKILAQAMVDTLAPLRAKRAELAEKPGLVS
HHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EVLAEGSRKAEVVARQTMEEARAALKV
HHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]