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The map label for this gene is argS

Identifier: 197118664

GI number: 197118664

Start: 2653124

End: 2654788

Strand: Reverse

Name: argS

Synonym: Gbem_2283

Alternate gene names: 197118664

Gene position: 2654788-2653124 (Counterclockwise)

Preceding gene: 197118665

Following gene: 197118663

Centisome position: 57.52

GC content: 62.52

Gene sequence:

>1665_bases
ATGAAGGAGCAGCTGCGCGCATGCATCCTGAAGGGAATCGAGGGGTGTTTCGCCGACGGCACGCTCACCTCTGGTGAAGT
ACCGGCTATCAACGTGGAGAAGCCGGCGCATGCCGAGCATGGCGATTTCGCCACCAACGTCGCCATGCAGATGGCCAAGC
AGCAGAGAAAGGCGCCGCGCGCCGTGGCCGAGATCCTGGTGGCGAAGCTCGCCGGCGCCTCTGACCTGATCGAGAGCCTT
GAGATCGCGGGCCCTGGCTTCATCAACTTCTTCATAAAAGACAGCGCCTGGAGAAGGACCCTCACCGAGATCGACCGCGC
CGGCGACGCCTGGGGCAAAAGCGGCATCGGCCGCGGCAAGAAGGTGCAGGTCGAGTTCGTCAGCGCCAACCCGACCGGGC
CTTTGCACATAGGGCACGGTCGCGGCGCCGCGACAGGGGACGCCGTTGCCTCGCTTTTATCCGCGGCGGGCTTCGACGTG
CAGCGCGAGTACTACATAAACGACGCCGGGAACCAGATGAACACCCTGGGGCTTTCCGGGCTTTTGCGCTACAAGGAACT
CCTGGGGGAGAAGATCGACTTCCCCGAGACCTGCTACCAGGGCGACTACATGAAGGATATCGCCCGTGACGCGGTCACCA
AGTACGGGGACCGGTTCCTGAAGGTATCCCAGGAGGATGGGGTAGCCTTCTTCTCTAAGATGGGGGGGGACCTGATCCTC
GCCGGGATCGACCAGGACCTGCAGGACTTCGGCATCCGTTTCGACCACTGGTTCTCCGAACAGTCGCTCTTCGACGAGGG
TAAGGTGAAATCCGCCATCGAGGAGATGCAGGCCAAGGGGCTCATCTACGAGCAGGAGGGGGCGCTCTGGTTCCGCACCA
CCGACTACGGCGACGACAAGGACCGCGTCGTGGTGAGGAGCAACGGGGTCACCACCTATTTTGCCTCCGACATCGCCTAC
CACAGGGACAAGTTCGCCCGGGGCTTTGACTGGGTCATCGACGTCTGGGGCGCCGACCATCACGGCTACGTCCCGAGGCT
TAAGAGCGTGGTGCAGGGGCTTGGGCGCGACGCCTCCGACCTCGGCATCATTTTGGTGCAGCTCGTTTCGCTTTTGCGCG
ACGGGGTGCCGGTTGCCATGTCCACCAGAAGCGGCGAGTTCGTGACACTGAAGGAGGTCGTCGACGAGGTCGGGCGCGAT
GCGGCCCGCTTCTTCTTCCTGATGCGCCGCTCGGACAGCCAGCTCGATTTCGACCTGGAACTTGCCAAGCGCCAGAGTAA
CGACAACCCGGTCTACTACGTACAGTACGCCCACGCGAGGATCAAGAGCATCTTCGACACCGCTAGGGAAAGGGGGGTGG
AGCCGCGCTTCGACAGCGTGAAGCTGGAACTCCTGCAGACTCCCGAGGACCTGAGCCTGGTCAAGAAACTCTCCGTCTAC
CCGGAGATCCTGGAAGGGGGCGCGGTGAACTTCGAGCCGCACCGGATCACCTACTACCTGCAGGAGCTTGCCGGCGAATT
CCACAGCTTCTACAACAAAAGCCGCGTGATCACCCCCGAAGAGCCGGAGCTGACCCAGGCGAGGCTTTTCCTGCTGCATT
GCGTCGCCATCACCCTCAAAAACGCGCTCACCGTCCTCGGCATCTCGGCGCCGGAAAGGATGTAG

Upstream 100 bases:

>100_bases
TCTGCGTCGCCGACGGGGGAGCACGCTGCCCCGACTTCACGCGCGACGTCACCATAAAGTCCGTGCCAGCCACGGAGGAA
GAGAAAAGGGAGGAGAAGAT

Downstream 100 bases:

>100_bases
GGGAGTTTCATGCGGCTTGATTACAGCGATAAGGTCGCGGCCCTGAGGGAGAGCCCTGAGCGAAAACCGGTGCAGAAACC
TGCACCCAAGAACCGGCCGC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MKEQLRACILKGIEGCFADGTLTSGEVPAINVEKPAHAEHGDFATNVAMQMAKQQRKAPRAVAEILVAKLAGASDLIESL
EIAGPGFINFFIKDSAWRRTLTEIDRAGDAWGKSGIGRGKKVQVEFVSANPTGPLHIGHGRGAATGDAVASLLSAAGFDV
QREYYINDAGNQMNTLGLSGLLRYKELLGEKIDFPETCYQGDYMKDIARDAVTKYGDRFLKVSQEDGVAFFSKMGGDLIL
AGIDQDLQDFGIRFDHWFSEQSLFDEGKVKSAIEEMQAKGLIYEQEGALWFRTTDYGDDKDRVVVRSNGVTTYFASDIAY
HRDKFARGFDWVIDVWGADHHGYVPRLKSVVQGLGRDASDLGIILVQLVSLLRDGVPVAMSTRSGEFVTLKEVVDEVGRD
AARFFFLMRRSDSQLDFDLELAKRQSNDNPVYYVQYAHARIKSIFDTARERGVEPRFDSVKLELLQTPEDLSLVKKLSVY
PEILEGGAVNFEPHRITYYLQELAGEFHSFYNKSRVITPEEPELTQARLFLLHCVAITLKNALTVLGISAPERM

Sequences:

>Translated_554_residues
MKEQLRACILKGIEGCFADGTLTSGEVPAINVEKPAHAEHGDFATNVAMQMAKQQRKAPRAVAEILVAKLAGASDLIESL
EIAGPGFINFFIKDSAWRRTLTEIDRAGDAWGKSGIGRGKKVQVEFVSANPTGPLHIGHGRGAATGDAVASLLSAAGFDV
QREYYINDAGNQMNTLGLSGLLRYKELLGEKIDFPETCYQGDYMKDIARDAVTKYGDRFLKVSQEDGVAFFSKMGGDLIL
AGIDQDLQDFGIRFDHWFSEQSLFDEGKVKSAIEEMQAKGLIYEQEGALWFRTTDYGDDKDRVVVRSNGVTTYFASDIAY
HRDKFARGFDWVIDVWGADHHGYVPRLKSVVQGLGRDASDLGIILVQLVSLLRDGVPVAMSTRSGEFVTLKEVVDEVGRD
AARFFFLMRRSDSQLDFDLELAKRQSNDNPVYYVQYAHARIKSIFDTARERGVEPRFDSVKLELLQTPEDLSLVKKLSVY
PEILEGGAVNFEPHRITYYLQELAGEFHSFYNKSRVITPEEPELTQARLFLLHCVAITLKNALTVLGISAPERM
>Mature_554_residues
MKEQLRACILKGIEGCFADGTLTSGEVPAINVEKPAHAEHGDFATNVAMQMAKQQRKAPRAVAEILVAKLAGASDLIESL
EIAGPGFINFFIKDSAWRRTLTEIDRAGDAWGKSGIGRGKKVQVEFVSANPTGPLHIGHGRGAATGDAVASLLSAAGFDV
QREYYINDAGNQMNTLGLSGLLRYKELLGEKIDFPETCYQGDYMKDIARDAVTKYGDRFLKVSQEDGVAFFSKMGGDLIL
AGIDQDLQDFGIRFDHWFSEQSLFDEGKVKSAIEEMQAKGLIYEQEGALWFRTTDYGDDKDRVVVRSNGVTTYFASDIAY
HRDKFARGFDWVIDVWGADHHGYVPRLKSVVQGLGRDASDLGIILVQLVSLLRDGVPVAMSTRSGEFVTLKEVVDEVGRD
AARFFFLMRRSDSQLDFDLELAKRQSNDNPVYYVQYAHARIKSIFDTARERGVEPRFDSVKLELLQTPEDLSLVKKLSVY
PEILEGGAVNFEPHRITYYLQELAGEFHSFYNKSRVITPEEPELTQARLFLLHCVAITLKNALTVLGISAPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=594, Percent_Identity=24.0740740740741, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI197100773, Length=593, Percent_Identity=25.4637436762226, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1788184, Length=571, Percent_Identity=26.0945709281961, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71985061, Length=607, Percent_Identity=26.3591433278418, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71985068, Length=571, Percent_Identity=26.7950963222417, Blast_Score=114, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320548, Length=530, Percent_Identity=25.8490566037736, Blast_Score=118, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6321883, Length=543, Percent_Identity=25.7826887661142, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI18859963, Length=614, Percent_Identity=24.9185667752443, Blast_Score=101, Evalue=2e-21,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_GEOBB (B5EEF0)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002139091.1
- ProteinModelPortal:   B5EEF0
- GeneID:   6782279
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_2283
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 61653; Mature: 61653

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQLRACILKGIEGCFADGTLTSGEVPAINVEKPAHAEHGDFATNVAMQMAKQQRKAPR
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AVAEILVAKLAGASDLIESLEIAGPGFINFFIKDSAWRRTLTEIDRAGDAWGKSGIGRGK
HHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCC
KVQVEFVSANPTGPLHIGHGRGAATGDAVASLLSAAGFDVQREYYINDAGNQMNTLGLSG
EEEEEEEECCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHH
LLRYKELLGEKIDFPETCYQGDYMKDIARDAVTKYGDRFLKVSQEDGVAFFSKMGGDLIL
HHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHCCCCEEE
AGIDQDLQDFGIRFDHWFSEQSLFDEGKVKSAIEEMQAKGLIYEQEGALWFRTTDYGDDK
ECCCCCHHHHCCCHHHHCCHHHHHCCHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCCC
DRVVVRSNGVTTYFASDIAYHRDKFARGFDWVIDVWGADHHGYVPRLKSVVQGLGRDASD
CEEEEECCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHH
LGIILVQLVSLLRDGVPVAMSTRSGEFVTLKEVVDEVGRDAARFFFLMRRSDSQLDFDLE
HHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHCCHHHHHHHHHHCCCCCCCEEHH
LAKRQSNDNPVYYVQYAHARIKSIFDTARERGVEPRFDSVKLELLQTPEDLSLVKKLSVY
HHHCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCEEHEECCCCHHHHHHHHHHHH
PEILEGGAVNFEPHRITYYLQELAGEFHSFYNKSRVITPEEPELTQARLFLLHCVAITLK
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
NALTVLGISAPERM
HHHHEEECCCCCCC
>Mature Secondary Structure
MKEQLRACILKGIEGCFADGTLTSGEVPAINVEKPAHAEHGDFATNVAMQMAKQQRKAPR
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AVAEILVAKLAGASDLIESLEIAGPGFINFFIKDSAWRRTLTEIDRAGDAWGKSGIGRGK
HHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCC
KVQVEFVSANPTGPLHIGHGRGAATGDAVASLLSAAGFDVQREYYINDAGNQMNTLGLSG
EEEEEEEECCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHH
LLRYKELLGEKIDFPETCYQGDYMKDIARDAVTKYGDRFLKVSQEDGVAFFSKMGGDLIL
HHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHCCCCEEE
AGIDQDLQDFGIRFDHWFSEQSLFDEGKVKSAIEEMQAKGLIYEQEGALWFRTTDYGDDK
ECCCCCHHHHCCCHHHHCCHHHHHCCHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCCC
DRVVVRSNGVTTYFASDIAYHRDKFARGFDWVIDVWGADHHGYVPRLKSVVQGLGRDASD
CEEEEECCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHH
LGIILVQLVSLLRDGVPVAMSTRSGEFVTLKEVVDEVGRDAARFFFLMRRSDSQLDFDLE
HHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHCCHHHHHHHHHHCCCCCCCEEHH
LAKRQSNDNPVYYVQYAHARIKSIFDTARERGVEPRFDSVKLELLQTPEDLSLVKKLSVY
HHHCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCEEHEECCCCHHHHHHHHHHHH
PEILEGGAVNFEPHRITYYLQELAGEFHSFYNKSRVITPEEPELTQARLFLLHCVAITLK
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
NALTVLGISAPERM
HHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA